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Volumn , Issue , 2010, Pages

Transplantation of Dopamine Neurons: Extent and Mechanisms of Functional Recovery in Rodent Models of Parkinson's Disease

Author keywords

Dopamine neurons; Parkinson's disease; Transplantation

Indexed keywords


EID: 84918862063     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1093/acprof:oso/9780195373035.003.0032     Document Type: Chapter
Times cited : (7)

References (233)
  • 1
    • 0015444837 scopus 로고
    • Brain tissue transplanted to the anterior chamber of the eye. 1. Fluorescence histochemistry of immature catecholamine and 5-hydroxytryptamine neurons innervating the iris
    • Olson L, Seiger Å. Brain tissue transplanted to the anterior chamber of the eye. 1. Fluorescence histochemistry of immature catecholamine and 5-hydroxytryptamine neurons innervating the iris. Z Zellforsch. 1972;195: 175-194.
    • (1972) Z Zellforsch. , vol.195 , pp. 175-194
    • Olson, L.1    Å, S.2
  • 2
    • 0017119186 scopus 로고
    • Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path
    • Björklund A, Stenevi U, Svendgaard N-A. Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path. Nature. 1976;262: 787-790.
    • (1976) Nature. , vol.262 , pp. 787-790
    • Björklund, A.1    Stenevi, U.2    Svendgaard, N.-A.3
  • 3
    • 0017158756 scopus 로고
    • Transplantation of central and peripheral monoamine neurons to the adult rat brain: techniques and conditions for survival
    • Stenevi U, Björklund A, Svendgaard N-A. Transplantation of central and peripheral monoamine neurons to the adult rat brain: techniques and conditions for survival. Brain Re.s 1976;114: 1-20.
    • (1976) Brain Re.s , vol.114 , pp. 1-20
    • Stenevi, U.1    Björklund, A.2    Svendgaard, N.-A.3
  • 4
    • 0018778418 scopus 로고
    • Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system
    • Perlow MJ, Freed WJ, Hoffer BJ, Seiger Å, Olson L, Wyatt RJ. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science. 1979;204: 643-647.
    • (1979) Science. , vol.204 , pp. 643-647
    • Perlow, M.J.1    Freed, W.J.2    Hoffer, B.J.3    Å, S.4    Olson, L.5    Wyatt, R.J.6
  • 5
    • 0018695489 scopus 로고
    • Reconstruction of the nigrostriatal dopamine pathway by intracerebral transplants
    • Björklund A, Stenevi U. Reconstruction of the nigrostriatal dopamine pathway by intracerebral transplants. Brain Res. 1979;177: 555-560.
    • (1979) Brain Res. , vol.177 , pp. 555-560
    • Björklund, A.1    Stenevi, U.2
  • 6
    • 0014376793 scopus 로고
    • 6-Hydroxy-dopamine induced degeneration of central monoamine neurons
    • Ungerstedt U. 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. Eur J Pharmacol. 1968;5: 107-110.
    • (1968) Eur J Pharmacol. , vol.5 , pp. 107-110
    • Ungerstedt, U.1
  • 7
    • 0030175258 scopus 로고    scopus 로고
    • Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae
    • Schwarting RKW, Huston JP. Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae. Prog Neurobiol. 1996;49: 215-266.
    • (1996) Prog Neurobiol. , vol.49 , pp. 215-266
    • Schwarting, R.K.W.1    Huston, J.P.2
  • 8
    • 34247469020 scopus 로고    scopus 로고
    • Dopamine neuron systems in the brain: an update
    • Björklund A, Dunnett SB. Dopamine neuron systems in the brain: an update. Trends Neurosci. 2007;30: 194-202.
    • (2007) Trends Neurosci. , vol.30 , pp. 194-202
    • Björklund, A.1    Dunnett, S.B.2
  • 9
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behaviour in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt U, Arbuthnott GW. Quantitative recording of rotational behaviour in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system. Brain Res. 1970;24: 485-493.
    • (1970) Brain Res. , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2
  • 10
    • 0030272769 scopus 로고    scopus 로고
    • The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments
    • Schwarting RKW, Huston JP. The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments. Prog Neurobiol. 1996;50: 275-331.
    • (1996) Prog Neurobiol. , vol.50 , pp. 275-331
    • Schwarting, R.K.W.1    Huston, J.P.2
  • 11
    • 77957235600 scopus 로고    scopus 로고
    • Motor functions of the nigrostriatal dopamine system: studies of lesions and behaviour
    • Dunnett SB, Bentivoglio M, Björklund A, Hökfelt T, eds, Amsterdam: Elsevier
    • Dunnett SB. Motor functions of the nigrostriatal dopamine system: studies of lesions and behaviour. In: Dunnett SB, Bentivoglio M, Björklund A, Hökfelt T, eds. Handbook of Chemical Neuroanatomy. Vol. 21. Dopamine. Amsterdam: Elsevier; 2005;235-299.
    • (2005) Handbook of Chemical Neuroanatomy. Vol. 21. Dopamine. , pp. 235-299
    • Dunnett, S.B.1
  • 12
    • 0040368216 scopus 로고    scopus 로고
    • Parkinson's disease: prospects for novel restorative and neuroprotective treatments
    • Dunnett SB, Björklund A. Parkinson's disease: prospects for novel restorative and neuroprotective treatments. Nature Suppl. 1999;399: 32-39.
    • (1999) Nature Suppl. , vol.399 , pp. 32-39
    • Dunnett, S.B.1    Björklund, A.2
  • 13
    • 0032143368 scopus 로고    scopus 로고
    • Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
    • Kirik D, Rosenblad C, Björklund A. Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp Neurol. 1998;152: 259-277.
    • (1998) Exp Neurol. , vol.152 , pp. 259-277
    • Kirik, D.1    Rosenblad, C.2    Björklund, A.3
  • 14
    • 0025373167 scopus 로고
    • Compensations after lesions of central dopaminergic neurons: some clinical and basic implications
    • Zigmond MJ, Abercrombie ED, Berger TW, Grace AA, Stricker EM. Compensations after lesions of central dopaminergic neurons: some clinical and basic implications. Trends Neurosci. 1990;13: 290-296.
    • (1990) Trends Neurosci. , vol.13 , pp. 290-296
    • Zigmond, M.J.1    Abercrombie, E.D.2    Berger, T.W.3    Grace, A.A.4    Stricker, E.M.5
  • 15
    • 0001253251 scopus 로고
    • Intraocular transplantation in rodents: a detailed account of the procedure and examples of its use in neurobiology with special reference to brain tissue grafting
    • Olson L, Seiger Å, Strömberg I. Intraocular transplantation in rodents: a detailed account of the procedure and examples of its use in neurobiology with special reference to brain tissue grafting. Adv Cell Neurobiol. 1983;4: 407-442.
    • (1983) Adv Cell Neurobiol. , vol.4 , pp. 407-442
    • Olson, L.1    Å, S.2    Strömberg, I.3
  • 16
    • 0033453218 scopus 로고    scopus 로고
    • Dopamine cells in nigral grafts differentiate prior to implantation
    • Sinclair SR, Fawcett JW, Dunnett SB. Dopamine cells in nigral grafts differentiate prior to implantation. Eur J Neurosci. 1999;11: 4341-4348.
    • (1999) Eur J Neurosci. , vol.11 , pp. 4341-4348
    • Sinclair, S.R.1    Fawcett, J.W.2    Dunnett, S.B.3
  • 17
    • 0019135449 scopus 로고
    • Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra
    • Björklund A, Schmidt RH, Stenevi U. Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra. Cell Tissue Res. 1980;212: 39-45.
    • (1980) Cell Tissue Res. , vol.212 , pp. 39-45
    • Björklund, A.1    Schmidt, R.H.2    Stenevi, U.3
  • 19
    • 0019448060 scopus 로고
    • Intracerebral grafting of dissociated CNS tissue suspensions: a new approach for neuronal transplantation to deep brain sites
    • Schmidt RH, Björklund A, Stenevi U. Intracerebral grafting of dissociated CNS tissue suspensions: a new approach for neuronal transplantation to deep brain sites. Brain Res. 1981;218: 347-356.
    • (1981) Brain Res. , vol.218 , pp. 347-356
    • Schmidt, R.H.1    Björklund, A.2    Stenevi, U.3
  • 20
    • 0023933288 scopus 로고
    • Survival and function of dissociated rat dopamine neurons grafted at different developmental stages or after being cultured in vitro
    • Brundin P, Barbin G, Strecker RE, Isacson O, Prochiantz A, Björklund A. Survival and function of dissociated rat dopamine neurons grafted at different developmental stages or after being cultured in vitro. Dev Brain Res. 1988;467: 233-243.
    • (1988) Dev Brain Res. , vol.467 , pp. 233-243
    • Brundin, P.1    Barbin, G.2    Strecker, R.E.3    Isacson, O.4    Prochiantz, A.5    Björklund, A.6
  • 21
    • 28144438531 scopus 로고    scopus 로고
    • Delivery of the sonic hedgehog or glial derived neurotrophic factor to dopaminerich grafts in a rat model of Parkinson's disease using adenoviral vectors. Increased yield of dopamine cells is dependent on embryonic donor age
    • Torres EM, Monville C, Lowenstein PR, Castro MG, Dunnett SB. Delivery of the sonic hedgehog or glial derived neurotrophic factor to dopaminerich grafts in a rat model of Parkinson's disease using adenoviral vectors. Increased yield of dopamine cells is dependent on embryonic donor age. Brain Res Bull. 2005;68: 31-41.
    • (2005) Brain Res Bull. , vol.68 , pp. 31-41
    • Torres, E.M.1    Monville, C.2    Lowenstein, P.R.3    Castro, M.G.4    Dunnett, S.B.5
  • 22
    • 34248996634 scopus 로고    scopus 로고
    • Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease
    • Torres EM, Monville C, Gates MA, Bagga V, Dunnett SB. Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease. Neuroscience. 2007;146: 1606-1617.
    • (2007) Neuroscience. , vol.146 , pp. 1606-1617
    • Torres, E.M.1    Monville, C.2    Gates, M.A.3    Bagga, V.4    Dunnett, S.B.5
  • 23
    • 0021000270 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites
    • Björklund A, Stenevi U, Schmidt RH, Dunnett SB, Gage FH. Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites. Acta Physiol Scand Suppl. 1983;522: 9-18.
    • (1983) Acta Physiol Scand Suppl. , vol.522 , pp. 9-18
    • Björklund, A.1    Stenevi, U.2    Schmidt, R.H.3    Dunnett, S.B.4    Gage, F.H.5
  • 24
    • 0025214503 scopus 로고
    • Effect of prior dopamine denervation on survival and fiber outgrowth from intrastriatal fetal mesencephalic grafts
    • Doucet G, Brundin P, Descarries L, Björklund A. Effect of prior dopamine denervation on survival and fiber outgrowth from intrastriatal fetal mesencephalic grafts. Eur J Neurosci. 1990;2: 279-290.
    • (1990) Eur J Neurosci. , vol.2 , pp. 279-290
    • Doucet, G.1    Brundin, P.2    Descarries, L.3    Björklund, A.4
  • 25
    • 0025909551 scopus 로고
    • Increase of striatal methionin enkephalin content following lesion of the nigrostriatal dopaminergic pathway in adult rats and reversal following the implantation of embryonic dopaminergic neuron--a quantitative immunohistochemical analysis
    • Manier M, Abrous DN, Feuerstein C, Le Moal M, Herman JP. Increase of striatal methionin enkephalin content following lesion of the nigrostriatal dopaminergic pathway in adult rats and reversal following the implantation of embryonic dopaminergic neuron--a quantitative immunohistochemical analysis. Neuroscience. 1991;42: 427-439.
    • (1991) Neuroscience. , vol.42 , pp. 427-439
    • Manier, M.1    Abrous, D.N.2    Feuerstein, C.3    Le Moal, M.4    Herman, J.P.5
  • 26
    • 0028084486 scopus 로고
    • Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat parkinson model
    • Nikkhah G, Cunningham MG, Jödicke A, Knappe U, Björklund A. Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat parkinson model. Brain Res. 1994;633: 133-143.
    • (1994) Brain Res. , vol.633 , pp. 133-143
    • Nikkhah, G.1    Cunningham, M.G.2    Jödicke, A.3    Knappe, U.4    Björklund, A.5
  • 27
    • 0033054208 scopus 로고    scopus 로고
    • Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants
    • Winkler C, Bentlage C, Nikkhah G, Samii M, Björklund A. Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants. Exp Neurol. 1999;155: 165-186.
    • (1999) Exp Neurol. , vol.155 , pp. 165-186
    • Winkler, C.1    Bentlage, C.2    Nikkhah, G.3    Samii, M.4    Björklund, A.5
  • 28
    • 0027979793 scopus 로고
    • Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation
    • Hudson JL, Bickford P, Johansson M, Hoffer BJ, Strömberg I. Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation. J Neurosci. 1994;14: 283-290.
    • (1994) J Neurosci. , vol.14 , pp. 283-290
    • Hudson, J.L.1    Bickford, P.2    Johansson, M.3    Hoffer, B.J.4    Strömberg, I.5
  • 29
    • 0026011993 scopus 로고
    • Specific reinnervation of lesioned mouse striatum by grafted mesencephalic dopaminergic neurons
    • Zuddas A, Corsini GU, Barker JL, Kopin IJ, Di Porzio U. Specific reinnervation of lesioned mouse striatum by grafted mesencephalic dopaminergic neurons. Eur J Neurosci. 1991;3: 72-85.
    • (1991) Eur J Neurosci. , vol.3 , pp. 72-85
    • Zuddas, A.1    Corsini, G.U.2    Barker, J.L.3    Kopin, I.J.4    Di Porzio, U.5
  • 30
    • 0001989283 scopus 로고
    • Evidence for the existence of monoaminecontaining neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons
    • Dahlström A, Fuxe K. Evidence for the existence of monoaminecontaining neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons. Acta Physiol Scand Suppl. 1964;232: 1-55.
    • (1964) Acta Physiol Scand Suppl. , vol.232 , pp. 1-55
    • Dahlström, A.1    Fuxe, K.2
  • 31
    • 0030924631 scopus 로고    scopus 로고
    • Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons
    • Haque NSK, Borghesani P, Isacson O. Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons. Cell Transplant. 1997;6: 239-248.
    • (1997) Cell Transplant. , vol.6 , pp. 239-248
    • Haque, N.S.K.1    Borghesani, P.2    Isacson, O.3
  • 32
    • 0021229785 scopus 로고
    • Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: evidence for selective growth regulation
    • Schultzberg M, Dunnett SB, Björklund A, et al. Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: evidence for selective growth regulation. Neuroscience. 1984;12: 17-32.
    • (1984) Neuroscience. , vol.12 , pp. 17-32
    • Schultzberg, M.1    Dunnett, S.B.2    Björklund, A.3
  • 33
    • 21844454972 scopus 로고    scopus 로고
    • Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections
    • Thompson L, Barraud P, Andersson E, Kirik D, Björklund A. Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. J Neurosci. 2005;25: 6467-6477.
    • (2005) J Neurosci. , vol.25 , pp. 6467-6477
    • Thompson, L.1    Barraud, P.2    Andersson, E.3    Kirik, D.4    Björklund, A.5
  • 34
    • 0035371071 scopus 로고    scopus 로고
    • Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene
    • Sawamoto K, Nakao N, Kakishita K, et al. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci. 2001;21: 3895-3903.
    • (2001) J Neurosci. , vol.21 , pp. 3895-3903
    • Sawamoto, K.1    Nakao, N.2    Kakishita, K.3
  • 35
    • 0021864514 scopus 로고
    • The electrophysiological properties of single units in mesencephalic transplants in rat brain
    • Arbuthnott GW, Dunnett SB, MacLeod N. The electrophysiological properties of single units in mesencephalic transplants in rat brain. Neurosci Lett. 1985;57: 205-210.
    • (1985) Neurosci Lett. , vol.57 , pp. 205-210
    • Arbuthnott, G.W.1    Dunnett, S.B.2    MacLeod, N.3
  • 36
    • 0024431280 scopus 로고
    • Host afferents into intrastriatal transplants of fetal ventral mesencephalon
    • Doucet G, Murata Y, Brundin P, et al. Host afferents into intrastriatal transplants of fetal ventral mesencephalon. Exp Neurol. 1989;106: 1-9.
    • (1989) Exp Neurol. , vol.106 , pp. 1-9
    • Doucet, G.1    Murata, Y.2    Brundin, P.3
  • 37
    • 0026089918 scopus 로고
    • Electrophysiological characteristics of cells within mesencephalon suspension grafts
    • Fisher LJ, Young SJ, Tepper JM, Groves PM, Gage FH. Electrophysiological characteristics of cells within mesencephalon suspension grafts. Neuroscience. 1991;40: 109-122.
    • (1991) Neuroscience. , vol.40 , pp. 109-122
    • Fisher, L.J.1    Young, S.J.2    Tepper, J.M.3    Groves, P.M.4    Gage, F.H.5
  • 38
    • 0021916279 scopus 로고
    • Efferent synaptic connections of grafted dopaminergic-neurons reinnervating the host neostriatum: a tyrosine hydroxylase immunocytochemical study
    • Freund TF, Bolam JP, Björklund A, et al. Efferent synaptic connections of grafted dopaminergic-neurons reinnervating the host neostriatum: a tyrosine hydroxylase immunocytochemical study. J Neurosci. 1985;5: 603-616.
    • (1985) J Neurosci. , vol.5 , pp. 603-616
    • Freund, T.F.1    Bolam, J.P.2    Björklund, A.3
  • 39
    • 0021930728 scopus 로고
    • Substantia nigra transplants into denervated striatum of the rat: ultrastructure of graft and host interconnections
    • Mahalik TJ, Finger TE, Strömberg I, Olson L. Substantia nigra transplants into denervated striatum of the rat: ultrastructure of graft and host interconnections. J Comp Neurol. 1985;240: 60-70.
    • (1985) J Comp Neurol. , vol.240 , pp. 60-70
    • Mahalik, T.J.1    Finger, T.E.2    Strömberg, I.3    Olson, L.4
  • 40
    • 0026071568 scopus 로고
    • Correlation of functional recovery after a 6-hydroxydopamine lesion with survival of grafted fetal neurons and release of dopamine in the striatum of the rat
    • Rioux L, Gaudin DP, Bui LK, Grégoire L, DiPaolo T, Bédard PJ. Correlation of functional recovery after a 6-hydroxydopamine lesion with survival of grafted fetal neurons and release of dopamine in the striatum of the rat. Neuroscience. 1991;40: 123-131.
    • (1991) Neuroscience. , vol.40 , pp. 123-131
    • Rioux, L.1    Gaudin, D.P.2    Bui, L.K.3    Grégoire, L.4    DiPaolo, T.5    Bédard, P.J.6
  • 41
    • 0023193770 scopus 로고
    • Auto-regulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis
    • Strecker RE, Sharp T, Brundin P, Zetterström T, Ungerstedt U, Björklund A. Auto-regulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis. Neuroscience. 1987;22: 169-178.
    • (1987) Neuroscience. , vol.22 , pp. 169-178
    • Strecker, R.E.1    Sharp, T.2    Brundin, P.3    Zetterström, T.4    Ungerstedt, U.5    Björklund, A.6
  • 42
    • 0026652551 scopus 로고
    • Regional differences in the regulation of dopamine and noradrenaline release in medial frontal cortex, nucleus accumbens and caudate-putamen: a microdialysis study in the rat
    • Cenci MA, Kalén P, Mandel RJ, Björklund A. Regional differences in the regulation of dopamine and noradrenaline release in medial frontal cortex, nucleus accumbens and caudate-putamen: a microdialysis study in the rat. Brain Res. 1992;581: 217-228.
    • (1992) Brain Res. , vol.581 , pp. 217-228
    • Cenci, M.A.1    Kalén, P.2    Mandel, R.J.3    Björklund, A.4
  • 43
    • 0026536649 scopus 로고
    • Dopaminergic transplants normalize amphetamine-and apomorphine-induced fos expression in the 6-hydroxydopamine-lesioned striatum
    • Cenci MA, Kalén P, Mandel RJ, Wictorin K, Björklund A. Dopaminergic transplants normalize amphetamine-and apomorphine-induced fos expression in the 6-hydroxydopamine-lesioned striatum. Neuroscience. 1992;46: 943-957.
    • (1992) Neuroscience. , vol.46 , pp. 943-957
    • Cenci, M.A.1    Kalén, P.2    Mandel, R.J.3    Wictorin, K.4    Björklund, A.5
  • 44
    • 0030811490 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase gene expression in the dopamine-denervated striatum: effects of intrastriatal fetal nigral transplants or chronic apomorphine treatment
    • Cenci MA, Campbell K, Björklund A. Glutamic acid decarboxylase gene expression in the dopamine-denervated striatum: effects of intrastriatal fetal nigral transplants or chronic apomorphine treatment. Mol Brain Res. 1997;48: 149-155.
    • (1997) Mol Brain Res. , vol.48 , pp. 149-155
    • Cenci, M.A.1    Campbell, K.2    Björklund, A.3
  • 45
    • 0026642024 scopus 로고
    • Intrastriatal dopamine-rich implants reverse the increase of dopamine D2 receptor mRNA levels caused by lesion of the nigrostriatal pathway: a quantitative in situ hybridization study
    • Chritin M, Savasta M, Mennicken F, et al. Intrastriatal dopamine-rich implants reverse the increase of dopamine D2 receptor mRNA levels caused by lesion of the nigrostriatal pathway: a quantitative in situ hybridization study. Eur J Neurosci. 1992;4: 663-672.
    • (1992) Eur J Neurosci. , vol.4 , pp. 663-672
    • Chritin, M.1    Savasta, M.2    Mennicken, F.3
  • 46
    • 0025980942 scopus 로고
    • Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra
    • Dawson TM, Dawson VL, Gage FH, Fisher LJ, Hunt MA, Wamsley JK. Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. Exp Neurol. 1991;111: 282-292.
    • (1991) Exp Neurol. , vol.111 , pp. 282-292
    • Dawson, T.M.1    Dawson, V.L.2    Gage, F.H.3    Fisher, L.J.4    Hunt, M.A.5    Wamsley, J.K.6
  • 47
    • 0026543094 scopus 로고
    • Intrastriatal dopamine-rich implants reverse the changes in dopamine D2 receptor densities caused by 6-hydroxydopamine lesion of the nigrostriatal pathway in rats: an autoradiographic study
    • Savasta M, Mennicken F, Chritin M, et al. Intrastriatal dopamine-rich implants reverse the changes in dopamine D2 receptor densities caused by 6-hydroxydopamine lesion of the nigrostriatal pathway in rats: an autoradiographic study. Neuroscience. 1992;46: 729-738.
    • (1992) Neuroscience. , vol.46 , pp. 729-738
    • Savasta, M.1    Mennicken, F.2    Chritin, M.3
  • 48
    • 0026011093 scopus 로고
    • Increased proenkephalin mRNA levels in the rat neostriatum following lesion of the ipsilateral nigrostriatal dopamine pathway with 1-methyl-4-phenylpyridinium ion (MPP+): reversal by embryonic nigral dopamine grafts
    • Sirinathsinghji DJS, Dunnett SB. Increased proenkephalin mRNA levels in the rat neostriatum following lesion of the ipsilateral nigrostriatal dopamine pathway with 1-methyl-4-phenylpyridinium ion (MPP+): reversal by embryonic nigral dopamine grafts. Mol Brain Res. 1991;9: 263-269.
    • (1991) Mol Brain Res. , vol.9 , pp. 263-269
    • Sirinathsinghji, D.J.S.1    Dunnett, S.B.2
  • 49
    • 0032830445 scopus 로고    scopus 로고
    • Reformation of the nigrostriatal pathway by fetal dopaminergic micrografts into the substantia nigra is critically dependent on the age of the host
    • Bentlage C, Nikkhah G, Cunningham MG, Björklund A. Reformation of the nigrostriatal pathway by fetal dopaminergic micrografts into the substantia nigra is critically dependent on the age of the host. Exp Neurol. 1999;159: 177-190.
    • (1999) Exp Neurol. , vol.159 , pp. 177-190
    • Bentlage, C.1    Nikkhah, G.2    Cunningham, M.G.3    Björklund, A.4
  • 50
    • 0029832802 scopus 로고    scopus 로고
    • Reconstruction of the nigrostriatal pathway by simultaneous intrastriatal and intranigral dopaminergic transplants
    • Mendez I, Sadi D, Hong M. Reconstruction of the nigrostriatal pathway by simultaneous intrastriatal and intranigral dopaminergic transplants. J Neurosci. 1996;16: 7216-7227.
    • (1996) J Neurosci. , vol.16 , pp. 7216-7227
    • Mendez, I.1    Sadi, D.2    Hong, M.3
  • 51
    • 0035873719 scopus 로고    scopus 로고
    • Enhancement of sensorimotor behavioral recovery in hemiparkinsonian rats with intrastriatal, intranigral, and intrasubthalamic nucleus dopaminergic transplants
    • Mukhida K, Baker KA, Sadi D, Mendez I. Enhancement of sensorimotor behavioral recovery in hemiparkinsonian rats with intrastriatal, intranigral, and intrasubthalamic nucleus dopaminergic transplants. J Neurosci. 2001;21: 3521-3530.
    • (2001) J Neurosci. , vol.21 , pp. 3521-3530
    • Mukhida, K.1    Baker, K.A.2    Sadi, D.3    Mendez, I.4
  • 52
    • 0029070864 scopus 로고
    • Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. I. Evidence for anatomical reconstruction of the nigrostriatal pathway
    • Nikkhah G, Cunningham MG, Cenci MA, McKay RD, Björklund A. Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. I. Evidence for anatomical reconstruction of the nigrostriatal pathway. J Neurosci. 1995;15: 3548-3561.
    • (1995) J Neurosci. , vol.15 , pp. 3548-3561
    • Nikkhah, G.1    Cunningham, M.G.2    Cenci, M.A.3    McKay, R.D.4    Björklund, A.5
  • 53
    • 0028868574 scopus 로고
    • Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres
    • Isacson O, Deacon TW, Pakzaban P, Galpern WR, Dinsmore J, Burns LH. Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres. Nat Med. 1995;1: 1189-1194.
    • (1995) Nat Med. , vol.1 , pp. 1189-1194
    • Isacson, O.1    Deacon, T.W.2    Pakzaban, P.3    Galpern, W.R.4    Dinsmore, J.5    Burns, L.H.6
  • 54
    • 0025147417 scopus 로고
    • Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts
    • Wictorin K, Brundin P, Gustavii B, Lindvall O, Björklund A. Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts. Nature. 1990;347: 556-558.
    • (1990) Nature. , vol.347 , pp. 556-558
    • Wictorin, K.1    Brundin, P.2    Gustavii, B.3    Lindvall, O.4    Björklund, A.5
  • 55
    • 0026030407 scopus 로고
    • Efferent projections to the host brain from intrastriatal striatal mouse-to-rat grafts: time course and tissue-type specificity as revealed by a mouse specific neuronal marker
    • Wictorin K, Lagenaur CF, Lund RD, Björklund A. Efferent projections to the host brain from intrastriatal striatal mouse-to-rat grafts: time course and tissue-type specificity as revealed by a mouse specific neuronal marker. Eur J Neurosci. 1991;3: 86-101.
    • (1991) Eur J Neurosci. , vol.3 , pp. 86-101
    • Wictorin, K.1    Lagenaur, C.F.2    Lund, R.D.3    Björklund, A.4
  • 56
    • 0030561505 scopus 로고    scopus 로고
    • Specific axon guidance factors persist in the adult brain as demonstrated by pig neuroblasts transplanted to the rat
    • Isacson O, Deacon TW. Specific axon guidance factors persist in the adult brain as demonstrated by pig neuroblasts transplanted to the rat. Neuroscience. 1996;75: 827-837.
    • (1996) Neuroscience. , vol.75 , pp. 827-837
    • Isacson, O.1    Deacon, T.W.2
  • 57
    • 34748861854 scopus 로고    scopus 로고
    • Reestablishment of damaged adult motor pathways by grafted embryonic cortical neurons
    • Gaillard A, Prestoz L, Dumartin B, et al. Reestablishment of damaged adult motor pathways by grafted embryonic cortical neurons. Nat Neurosci. 2007;10: 1294-1299.
    • (2007) Nat Neurosci. , vol.10 , pp. 1294-1299
    • Gaillard, A.1    Prestoz, L.2    Dumartin, B.3
  • 58
    • 0028346532 scopus 로고
    • Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts
    • Davies SJA, Field PM, Raisman G. Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts. J Neurosci. 1994;14: 1596-1612.
    • (1994) J Neurosci. , vol.14 , pp. 1596-1612
    • Davies, S.J.A.1    Field, P.M.2    Raisman, G.3
  • 59
    • 0022515813 scopus 로고
    • Cell suspension grafts of noradrenergic locus coeruleus neurons in rat hippocampus and spinal cord--reinnervation and transmitter turnover
    • Björklund A, Nornes H, Gage FH. Cell suspension grafts of noradrenergic locus coeruleus neurons in rat hippocampus and spinal cord--reinnervation and transmitter turnover. Neuroscience. 1986;18: 685-698.
    • (1986) Neuroscience. , vol.18 , pp. 685-698
    • Björklund, A.1    Nornes, H.2    Gage, F.H.3
  • 60
    • 0027444869 scopus 로고
    • Long axon growth from embryonic neurons transplanted into myelinated tracts of the adult rat spinal cord
    • Li Y, Raisman G. Long axon growth from embryonic neurons transplanted into myelinated tracts of the adult rat spinal cord. Brain Res. 1993;629: 115-127.
    • (1993) Brain Res. , vol.629 , pp. 115-127
    • Li, Y.1    Raisman, G.2
  • 61
    • 0026701417 scopus 로고
    • Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats
    • Wictorin K, Brundin P, Sauer H, Lindvall O, Björklund A. Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats. J Comp Neurol. 1992;323: 475-494.
    • (1992) J Comp Neurol. , vol.323 , pp. 475-494
    • Wictorin, K.1    Brundin, P.2    Sauer, H.3    Lindvall, O.4    Björklund, A.5
  • 62
    • 69249109574 scopus 로고    scopus 로고
    • Reconstruction of the nigro-striatal dopamine pathway in the adult mouse brain
    • in press
    • Thompson LH, Grealish S, Kirik D, Björklund A. Reconstruction of the nigro-striatal dopamine pathway in the adult mouse brain J Neurosci. 2009; in press.
    • (2009) J Neurosci.
    • Thompson, L.H.1    Grealish, S.2    Kirik, D.3    Björklund, A.4
  • 63
    • 0015176277 scopus 로고
    • Striatal dopamine release after amphetamine or nerve degeneration revealed by rotational behaviour
    • Ungerstedt U. Striatal dopamine release after amphetamine or nerve degeneration revealed by rotational behaviour. Acta Physiol Scand Supp. 1971;367: 49-68.
    • (1971) Acta Physiol Scand Supp. , vol.367 , pp. 49-68
    • Ungerstedt, U.1
  • 64
    • 0020987866 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. IV. Behavioral recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites
    • Dunnett SB, Björklund A, Schmidt RH, Stenevi U, Iversen SD. Intracerebral grafting of neuronal cell suspensions. IV. Behavioral recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites. Acta Physiol Scand Suppl. 1983;522: 29-37.
    • (1983) Acta Physiol Scand Suppl. , vol.522 , pp. 29-37
    • Dunnett, S.B.1    Björklund, A.2    Schmidt, R.H.3    Stenevi, U.4    Iversen, S.D.5
  • 65
  • 66
    • 0021000670 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism
    • Schmidt RH, Björklund A, Stenevi U, Dunnett SB, Gage FH. Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. Acta Physiol Scand Suppl. 1983;522: 19-28.
    • (1983) Acta Physiol Scand Suppl. , vol.522 , pp. 19-28
    • Schmidt, R.H.1    Björklund, A.2    Stenevi, U.3    Dunnett, S.B.4    Gage, F.H.5
  • 67
    • 0024511225 scopus 로고
    • Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier
    • Brundin P, Widner H, Nilsson OG, Strecker RE, Björklund A. Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier. Exp Brain Res. 1989;75: 195-207.
    • (1989) Exp Brain Res. , vol.75 , pp. 195-207
    • Brundin, P.1    Widner, H.2    Nilsson, O.G.3    Strecker, R.E.4    Björklund, A.5
  • 68
    • 0018825573 scopus 로고
    • Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing
    • Björklund A, Dunnett SB, Stenevi U, Lewis ME, Iversen SD. Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing. Brain Res. 1980;199: 307-333.
    • (1980) Brain Res. , vol.199 , pp. 307-333
    • Björklund, A.1    Dunnett, S.B.2    Stenevi, U.3    Lewis, M.E.4    Iversen, S.D.5
  • 69
    • 0015184103 scopus 로고
    • Postsynaptic supersensitivity after 6-hydroxydopamineinduced degeneration of the nigro-striatal dopamine system
    • Ungerstedt U. Postsynaptic supersensitivity after 6-hydroxydopamineinduced degeneration of the nigro-striatal dopamine system. Acta Physiol Scand Suppl. 1971;367: 69-93.
    • (1971) Acta Physiol Scand Suppl. , vol.367 , pp. 69-93
    • Ungerstedt, U.1
  • 70
    • 0021029852 scopus 로고
    • Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra
    • Freed WJ, Ko GN, Niehoff DL, et al. Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra. Science. 1983;222: 937-939.
    • (1983) Science. , vol.222 , pp. 937-939
    • Freed, W.J.1    Ko, G.N.2    Niehoff, D.L.3
  • 71
    • 0024156714 scopus 로고
    • Comparison of adrenal medullary, carotid body and PC12 cell grafts in 6-OHDA lesioned rats
    • Bing G, Notter MFD, Hansen JT, Gash DM. Comparison of adrenal medullary, carotid body and PC12 cell grafts in 6-OHDA lesioned rats. Brain Res Bull. 1988;20: 399-406.
    • (1988) Brain Res Bull. , vol.20 , pp. 399-406
    • Bing, G.1    Notter, M.F.D.2    Hansen, J.T.3    Gash, D.M.4
  • 72
    • 0024404613 scopus 로고
    • Comparison of adrenal and fetal nigral grafts on drug-induced rotation in rats with 6-OHDA lesions
    • Brown VJ, Dunnett SB. Comparison of adrenal and fetal nigral grafts on drug-induced rotation in rats with 6-OHDA lesions. Exp Brain Res. 1989;78: 214-218.
    • (1989) Exp Brain Res. , vol.78 , pp. 214-218
    • Brown, V.J.1    Dunnett, S.B.2
  • 73
    • 0023148924 scopus 로고
    • Chronic intrastriatal dopamine infusions in rats with unilateral lesions of the substantia nigra
    • Hargraves RW, Freed WJ. Chronic intrastriatal dopamine infusions in rats with unilateral lesions of the substantia nigra. Life Sci. 1987;40: 959-966.
    • (1987) Life Sci. , vol.40 , pp. 959-966
    • Hargraves, R.W.1    Freed, W.J.2
  • 74
    • 0037007106 scopus 로고    scopus 로고
    • Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAVmediated gene transfer
    • Kirik D, Georgievska B, Burger C, et al. Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAVmediated gene transfer. Proc Natl Acad Sci USA. 2002;99: 4708-4713.
    • (2002) Proc Natl Acad Sci USA. , vol.99 , pp. 4708-4713
    • Kirik, D.1    Georgievska, B.2    Burger, C.3
  • 75
    • 0018894295 scopus 로고
    • Circling behavior in rats with partial, unilateral nigro-striatal lesions: effects of amphetamine, apomorphine, and DOPA
    • Hefti F, Melamed E, Sahakian BJ, Wurtman RJ. Circling behavior in rats with partial, unilateral nigro-striatal lesions: effects of amphetamine, apomorphine, and DOPA. Pharmacol Biochem Behav. 1980;12: 185-188.
    • (1980) Pharmacol Biochem Behav. , vol.12 , pp. 185-188
    • Hefti, F.1    Melamed, E.2    Sahakian, B.J.3    Wurtman, R.J.4
  • 76
    • 0025846973 scopus 로고
    • Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts
    • Sauer H, Brundin P. Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. Rest Neurol Neurosci. 1991;2: 123-135.
    • (1991) Rest Neurol Neurosci. , vol.2 , pp. 123-135
    • Sauer, H.1    Brundin, P.2
  • 77
    • 0028819620 scopus 로고
    • The influence of donor age on the survival of solid and suspension intraparenchymal human embryonic nigral grafts
    • Freeman TB, Sanberg PR, Nauert GM, et al. The influence of donor age on the survival of solid and suspension intraparenchymal human embryonic nigral grafts. Cell Transplant. 1995;4: 141-154.
    • (1995) Cell Transplant. , vol.4 , pp. 141-154
    • Freeman, T.B.1    Sanberg, P.R.2    Nauert, G.M.3
  • 78
    • 0027282716 scopus 로고
    • A comparison of solid intraventricular and dissociated intraparenchymal fetal substantia nigra grafts in a rat model of Parkinson's disease: impaired graft survival is associated with high baseline rotational behavior
    • Heim RC, Willingham G, Freed WJ. A comparison of solid intraventricular and dissociated intraparenchymal fetal substantia nigra grafts in a rat model of Parkinson's disease: impaired graft survival is associated with high baseline rotational behavior. Exp Neurol. 1993;122: 5-15.
    • (1993) Exp Neurol. , vol.122 , pp. 5-15
    • Heim, R.C.1    Willingham, G.2    Freed, W.J.3
  • 79
    • 0027957150 scopus 로고
    • Vascularization and microvascular permeability in solid versus cell-suspension embryonic neural grafts
    • Leigh K, Elisevich K, Rogers KA. Vascularization and microvascular permeability in solid versus cell-suspension embryonic neural grafts. J Neurosurg. 1994;81: 272-283.
    • (1994) J Neurosurg. , vol.81 , pp. 272-283
    • Leigh, K.1    Elisevich, K.2    Rogers, K.A.3
  • 80
    • 0031916018 scopus 로고    scopus 로고
    • Differences in acquisition and full performance in skilled forelimb use as measured by the "staircase test" in five rat strains
    • Nikkhah G, Rosenthal C, Hedrich HJ, Samii M. Differences in acquisition and full performance in skilled forelimb use as measured by the "staircase test" in five rat strains. Behav Brain Res. 1998;92: 85-95.
    • (1998) Behav Brain Res. , vol.92 , pp. 85-95
    • Nikkhah, G.1    Rosenthal, C.2    Hedrich, H.J.3    Samii, M.4
  • 81
    • 0030198586 scopus 로고    scopus 로고
    • Xenotransplantation of porcine fetal ventral mesencephalon in a rat model of Parkinson's disease: functional recovery and graft morphology
    • Galpern WR, Burns LH, Deacon TW, Dinsmore J, Isacson O. Xenotransplantation of porcine fetal ventral mesencephalon in a rat model of Parkinson's disease: functional recovery and graft morphology. Exp Neurol. 1996;140: 1-13.
    • (1996) Exp Neurol. , vol.140 , pp. 1-13
    • Galpern, W.R.1    Burns, L.H.2    Deacon, T.W.3    Dinsmore, J.4    Isacson, O.5
  • 82
    • 0032939002 scopus 로고    scopus 로고
    • Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
    • Rosenblad C, Kirik D, Devaux B, Moffat B, Phillips HS, Björklund A. Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle. Eur J Neurosci. 1999;11: 1554-1566.
    • (1999) Eur J Neurosci. , vol.11 , pp. 1554-1566
    • Rosenblad, C.1    Kirik, D.2    Devaux, B.3    Moffat, B.4    Phillips, H.S.5    Björklund, A.6
  • 83
    • 0033559401 scopus 로고    scopus 로고
    • A GDNF-secreting clone of the Schwann cell line SCTM41 enhances survival and fibre outgrowth from embryonic nigral neurones grafted to the striatum and the lesioned substantia nigra
    • Wilby M, Sinclair SR, Muir EM, et al. A GDNF-secreting clone of the Schwann cell line SCTM41 enhances survival and fibre outgrowth from embryonic nigral neurones grafted to the striatum and the lesioned substantia nigra. J Neurosci. 1999;19: 2301-2312.
    • (1999) J Neurosci. , vol.19 , pp. 2301-2312
    • Wilby, M.1    Sinclair, S.R.2    Muir, E.M.3
  • 84
    • 0034589036 scopus 로고    scopus 로고
    • Improving the survival of grafted embryonic dopamine neurons in rodent models of Parkinson's disease
    • Castilho RF, Hansson O, Brundin P. Improving the survival of grafted embryonic dopamine neurons in rodent models of Parkinson's disease. Prog Brain Res. 2000;127: 203-231.
    • (2000) Prog Brain Res. , vol.127 , pp. 203-231
    • Castilho, R.F.1    Hansson, O.2    Brundin, P.3
  • 86
    • 0027970324 scopus 로고
    • Ibotenic acid lesions of the striatum reduce druginduced rotation in the 6-hydroxydopamine-lesioned rat
    • Barker RA, Dunnett SB. Ibotenic acid lesions of the striatum reduce druginduced rotation in the 6-hydroxydopamine-lesioned rat. Exp Brain Res. 1994;101: 365-374.
    • (1994) Exp Brain Res. , vol.101 , pp. 365-374
    • Barker, R.A.1    Dunnett, S.B.2
  • 87
    • 0017159393 scopus 로고
    • Activation-induced restoration of sensorimotor functions in rats with dopamine-depleting brain lesions
    • Marshall JF, Levitan D, Stricker EM. Activation-induced restoration of sensorimotor functions in rats with dopamine-depleting brain lesions. J Comp Physiol Psychol. 1976;90: 536-546.
    • (1976) J Comp Physiol Psychol. , vol.90 , pp. 536-546
    • Marshall, J.F.1    Levitan, D.2    Stricker, E.M.3
  • 88
    • 0015182655 scopus 로고
    • Adipsia and aphagia after 6-hydroxydopamine-induced degeneration of the nigro-striatal dopamine system
    • Ungerstedt U. Adipsia and aphagia after 6-hydroxydopamine-induced degeneration of the nigro-striatal dopamine system. Acta Physiol Scand Suppl. 1971;367: 96-122.
    • (1971) Acta Physiol Scand Suppl. , vol.367 , pp. 96-122
    • Ungerstedt, U.1
  • 89
    • 0015528861 scopus 로고
    • Deficits in feeding behavior after intraventricular injection of 6-hydroxydopamine in rats
    • Zigmond MJ, Stricker EM. Deficits in feeding behavior after intraventricular injection of 6-hydroxydopamine in rats. Science. 1972;177: 1211-1214.
    • (1972) Science. , vol.177 , pp. 1211-1214
    • Zigmond, M.J.1    Stricker, E.M.2
  • 90
    • 0019858470 scopus 로고
    • Behavioral recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. 2. Bilateral lesions
    • Dunnett SB, Björklund A, Stenevi U, Iversen SD. Behavioral recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. 2. Bilateral lesions. Brain Res. 1981;229: 457-470.
    • (1981) Brain Res. , vol.229 , pp. 457-470
    • Dunnett, S.B.1    Björklund, A.2    Stenevi, U.3    Iversen, S.D.4
  • 91
    • 0019855516 scopus 로고
    • Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway
    • Dunnett SB, Björklund A, Stenevi U, Iversen SD. Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway. Brain Res. 1981;229: 209-217.
    • (1981) Brain Res. , vol.229 , pp. 209-217
    • Dunnett, S.B.1    Björklund, A.2    Stenevi, U.3    Iversen, S.D.4
  • 92
    • 0020989671 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. V. Behavioral recovery in rats with bilateral 6-OHDA lesions following implantation of nigral cell suspensions
    • Dunnett SB, Björklund A, Schmidt RH, Stenevi U, Iversen SD. Intracerebral grafting of neuronal cell suspensions. V. Behavioral recovery in rats with bilateral 6-OHDA lesions following implantation of nigral cell suspensions. Acta Physiol Scand Suppl. 1983;522: 39-47.
    • (1983) Acta Physiol Scand Suppl. , vol.522 , pp. 39-47
    • Dunnett, S.B.1    Björklund, A.2    Schmidt, R.H.3    Stenevi, U.4    Iversen, S.D.5
  • 93
    • 0023583618 scopus 로고
    • Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion
    • Brundin P, Strecker RE, Londos E, Björklund A. Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion. Exp Brain Res. 1987;69: 183-194.
    • (1987) Exp Brain Res. , vol.69 , pp. 183-194
    • Brundin, P.1    Strecker, R.E.2    Londos, E.3    Björklund, A.4
  • 94
    • 0023191549 scopus 로고
    • Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions
    • Dunnett SB, Whishaw IQ, Rogers DC, Jones GH. Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions. Brain Res. 1987;415: 63-78.
    • (1987) Brain Res. , vol.415 , pp. 63-78
    • Dunnett, S.B.1    Whishaw, I.Q.2    Rogers, D.C.3    Jones, G.H.4
  • 95
    • 0025108166 scopus 로고
    • Effects of nigral and striatal grafts on skilled forelimb use in the rat
    • Montoya CP, Astell S, Dunnett SB. Effects of nigral and striatal grafts on skilled forelimb use in the rat. Prog Brain Res. 1990;82: 459-466.
    • (1990) Prog Brain Res. , vol.82 , pp. 459-466
    • Montoya, C.P.1    Astell, S.2    Dunnett, S.B.3
  • 96
    • 0027319426 scopus 로고
    • Dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood
    • Abrous DN, Torres EM, Dunnett SB. Dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood. Neuroscience. 1993;54: 657-668.
    • (1993) Neuroscience. , vol.54 , pp. 657-668
    • Abrous, D.N.1    Torres, E.M.2    Dunnett, S.B.3
  • 97
    • 0029046161 scopus 로고
    • Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. II. Transplant-induced behavioral recovery
    • Nikkhah G, Cunningham MG, McKay R, Björklund A. Dopaminergic microtransplants into the substantia nigra of neonatal rats with bilateral 6-OHDA lesions. II. Transplant-induced behavioral recovery. J Neurosci. 1995;15: 3562-3570.
    • (1995) J Neurosci. , vol.15 , pp. 3562-3570
    • Nikkhah, G.1    Cunningham, M.G.2    McKay, R.3    Björklund, A.4
  • 98
    • 0024392390 scopus 로고
    • Nigrostriatal reconstruction after 6-OHDA lesions in rats: combination of dopamine-rich nigral grafts and nigrostriatal bridge grafts
    • Dunnett SB, Rogers DC, Richards SJ. Nigrostriatal reconstruction after 6-OHDA lesions in rats: combination of dopamine-rich nigral grafts and nigrostriatal bridge grafts. Exp Brain Res. 1989;75: 523-535.
    • (1989) Exp Brain Res. , vol.75 , pp. 523-535
    • Dunnett, S.B.1    Rogers, D.C.2    Richards, S.J.3
  • 99
    • 0029944565 scopus 로고    scopus 로고
    • Functional and anatomical reconstruction of the 6-hydroxydopamine lesioned nigrostriatal system of the adult rat
    • Brecknell JE, Haque NS, Du JS, et al. Functional and anatomical reconstruction of the 6-hydroxydopamine lesioned nigrostriatal system of the adult rat. Neuroscience. 1996;71: 913-925.
    • (1996) Neuroscience. , vol.71 , pp. 913-925
    • Brecknell, J.E.1    Haque, N.S.2    Du, J.S.3
  • 100
    • 0035871386 scopus 로고    scopus 로고
    • Growth and functional efficacy of intrastriatal nigral transplants depends on the extent of nigrostriatal degeneration
    • Kirik D, Winkler C, Björklund A. Growth and functional efficacy of intrastriatal nigral transplants depends on the extent of nigrostriatal degeneration. J Neurosci. 2001;21: 2889-2896.
    • (2001) J Neurosci. , vol.21 , pp. 2889-2896
    • Kirik, D.1    Winkler, C.2    Björklund, A.3
  • 101
    • 28144440866 scopus 로고    scopus 로고
    • The corridor task: a simple test of lateralised response selection and neglect sensitive to unilateral dopamine deafferentation and graft-derived replacement in the striatum
    • Dowd E, Monville C, Torres EM, Dunnett SB. The corridor task: a simple test of lateralised response selection and neglect sensitive to unilateral dopamine deafferentation and graft-derived replacement in the striatum. Brain Res Bull. 2005;68: 24-30.
    • (2005) Brain Res Bull. , vol.68 , pp. 24-30
    • Dowd, E.1    Monville, C.2    Torres, E.M.3    Dunnett, S.B.4
  • 102
    • 34249801477 scopus 로고    scopus 로고
    • The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease
    • Breysse N, Carlsson T, Winkler C, Björklund A, Kirik D. The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease. J Neurosci. 2007;27: 5849-5856.
    • (2007) J Neurosci. , vol.27 , pp. 5849-5856
    • Breysse, N.1    Carlsson, T.2    Winkler, C.3    Björklund, A.4    Kirik, D.5
  • 103
    • 0028360140 scopus 로고
    • Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model
    • Nikkhah G, Bentlage C, Cunningham MG, Björklund A. Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. J Neurosci. 1994;14: 3449-3461.
    • (1994) J Neurosci. , vol.14 , pp. 3449-3461
    • Nikkhah, G.1    Bentlage, C.2    Cunningham, M.G.3    Björklund, A.4
  • 104
    • 0034626625 scopus 로고    scopus 로고
    • Simultaneous intrastriatal and intranigral dopaminergic grafts in the Parkinsonian rat model: role of the intranigral graft
    • Baker KA, Sadi D, Hong M, Mendez I. Simultaneous intrastriatal and intranigral dopaminergic grafts in the Parkinsonian rat model: role of the intranigral graft. J Comp Neurol. 2000;426: 106-116.
    • (2000) J Comp Neurol. , vol.426 , pp. 106-116
    • Baker, K.A.1    Sadi, D.2    Hong, M.3    Mendez, I.4
  • 105
    • 0034589149 scopus 로고    scopus 로고
    • Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement
    • Winkler C, Kirik D, Björklund A, Dunnett SB. Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement. Prog Brain Res. 2000;127: 233-265.
    • (2000) Prog Brain Res. , vol.127 , pp. 233-265
    • Winkler, C.1    Kirik, D.2    Björklund, A.3    Dunnett, S.B.4
  • 106
    • 0031402010 scopus 로고    scopus 로고
    • An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism
    • Rozas G, Guerra MJ, Labandeira-García JL. An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism. Brain Res Prot. 1997;2: 75-84.
    • (1997) Brain Res Prot. , vol.2 , pp. 75-84
    • Rozas, G.1    Guerra, M.J.2    Labandeira-García, J.L.3
  • 107
    • 0000431473 scopus 로고    scopus 로고
    • Intervention strategies for degeneration of dopamine neurons in Parkinsonism: optimizing behavioral assessment of outcome
    • Emerich DF, Dean RL, Sanberg PR, eds, Totowa, NJ: Humana Press
    • Schallert T, Tillerson JL. Intervention strategies for degeneration of dopamine neurons in Parkinsonism: optimizing behavioral assessment of outcome. In: Emerich DF, Dean RL, Sanberg PR, eds. Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic. Totowa, NJ: Humana Press; 2000;131-151.
    • (2000) Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic. , pp. 131-151
    • Schallert, T.1    Tillerson, J.L.2
  • 108
    • 84882327552 scopus 로고    scopus 로고
    • Utility of 6-hydroxydopamine lesioned rats in the preclinical screening of novel treatments for Parkinson disease
    • LeDoux M, ed, Amsterdam, the Netherlands: Elsevier
    • Cenci MA, Lundblad M. Utility of 6-hydroxydopamine lesioned rats in the preclinical screening of novel treatments for Parkinson disease. In: LeDoux M, ed. Animal Models of Movement Disorders. Amsterdam, the Netherlands: Elsevier; 2005;193-209.
    • (2005) Animal Models of Movement Disorders. , pp. 193-209
    • Cenci, M.A.1    Lundblad, M.2
  • 109
    • 0029064091 scopus 로고
    • Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
    • Olsson M, Nikkhah G, Bentlage C, Björklund A. Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test. J Neurosci. 1995;15: 3863-3875.
    • (1995) J Neurosci. , vol.15 , pp. 3863-3875
    • Olsson, M.1    Nikkhah, G.2    Bentlage, C.3    Björklund, A.4
  • 110
    • 0031055595 scopus 로고    scopus 로고
    • Drug-free evaluation of rat models of parkinsonism and nigral grafts using a new automated rotarod test
    • Rozas G, Labandeira-García JL. Drug-free evaluation of rat models of parkinsonism and nigral grafts using a new automated rotarod test. Brain Res. 1997;749: 188-199.
    • (1997) Brain Res. , vol.749 , pp. 188-199
    • Rozas, G.1    Labandeira-García, J.L.2
  • 111
    • 0031863204 scopus 로고    scopus 로고
    • Dopaminergic graftinduced long-term recovery of complex sensorimotor behaviors in a rat model of Parkinson's disease
    • Nikkhah G, Rosenthal C, Falkenstein G, Samii M. Dopaminergic graftinduced long-term recovery of complex sensorimotor behaviors in a rat model of Parkinson's disease. Zentralbl Neurochi.r 1998;59: 97-103.
    • (1998) Zentralbl Neurochi.r , vol.59 , pp. 97-103
    • Nikkhah, G.1    Rosenthal, C.2    Falkenstein, G.3    Samii, M.4
  • 112
    • 0343674689 scopus 로고    scopus 로고
    • Complex sensorimotor behavioral changes after terminal striatal 6-OHDA lesion and transplantation of dopaminergic embryonic micrografts
    • Roedter A, Winkler C, Samii M, Nikkhah G. Complex sensorimotor behavioral changes after terminal striatal 6-OHDA lesion and transplantation of dopaminergic embryonic micrografts. Cell Transplant. 2001;9: 197-214.
    • (2001) Cell Transplant. , vol.9 , pp. 197-214
    • Roedter, A.1    Winkler, C.2    Samii, M.3    Nikkhah, G.4
  • 113
    • 46549086399 scopus 로고    scopus 로고
    • Recovery of functional deficits following early donor age (E12) ventral mesencephalic grafts in a rat model of Parkinson's disease
    • Torres EM, Dowd E, Dunnett SB. Recovery of functional deficits following early donor age (E12) ventral mesencephalic grafts in a rat model of Parkinson's disease. Neuroscience. 2008;154: 631-640.
    • (2008) Neuroscience. , vol.154 , pp. 631-640
    • Torres, E.M.1    Dowd, E.2    Dunnett, S.B.3
  • 114
    • 0029041475 scopus 로고
    • General cognitive ability following unilateral and bilateral fetal ventral mesencephalic tissue transplantation for treatment of Parkinson's disease
    • Sass KJ, Buchanan CP, Westerveld M, et al. General cognitive ability following unilateral and bilateral fetal ventral mesencephalic tissue transplantation for treatment of Parkinson's disease. Arch Neurol. 1995;52: 680-686.
    • (1995) Arch Neurol. , vol.52 , pp. 680-686
    • Sass, K.J.1    Buchanan, C.P.2    Westerveld, M.3
  • 115
    • 0038736561 scopus 로고    scopus 로고
    • [Neuropsychological testing of 5 patients with Parkinson's disease before and after neuron graft]
    • Leroy A, Michelet D, Mahieux F, et al. [Neuropsychological testing of 5 patients with Parkinson's disease before and after neuron graft]. Rev Neurol (Paris). 1996;152: 158-164.
    • (1996) Rev Neurol (Paris). , vol.152 , pp. 158-164
    • Leroy, A.1    Michelet, D.2    Mahieux, F.3
  • 117
    • 0019422901 scopus 로고
    • Dopaminergic A10 neurons and frontal system
    • Simon H. Dopaminergic A10 neurons and frontal system. J Physiol (Paris). 1981;77: 81-95.
    • (1981) J Physiol (Paris). , vol.77 , pp. 81-95
    • Simon, H.1
  • 118
    • 0020363241 scopus 로고
    • Neurotoxic lesions of ventrolateral but not anteromedial neostriatum in rats impair differential reinforcement of low rates (DRL) performance
    • Dunnett SB, Iversen SD. Neurotoxic lesions of ventrolateral but not anteromedial neostriatum in rats impair differential reinforcement of low rates (DRL) performance. Behav Brain Res. 1982;6: 213-226.
    • (1982) Behav Brain Res. , vol.6 , pp. 213-226
    • Dunnett, S.B.1    Iversen, S.D.2
  • 119
    • 0015794743 scopus 로고
    • Recovery of feeding and drinking by rats after intraventricular 6-hydroxydopamine or lateral hypothalamic lesions
    • Zigmond MJ, Stricker EM. Recovery of feeding and drinking by rats after intraventricular 6-hydroxydopamine or lateral hypothalamic lesions. Science. 1973;182: 717-720.
    • (1973) Science. , vol.182 , pp. 717-720
    • Zigmond, M.J.1    Stricker, E.M.2
  • 120
    • 0003010468 scopus 로고
    • Memories and habits: two neural systems
    • Lynch G, McGaugh JL, Weinberger NM, eds., New York, NY: Guilford Press
    • Mishkin M, Malamut B, Bachevalier J. Memories and habits: two neural systems. In: Lynch G, McGaugh JL, Weinberger NM, eds. Neurobiology of Learning and Memory. New York, NY: Guilford Press; 1984: 65-77.
    • (1984) Neurobiology of Learning and Memory. , pp. 65-77
    • Mishkin, M.1    Malamut, B.2    Bachevalier, J.3
  • 121
    • 0029980394 scopus 로고    scopus 로고
    • Memory, action and the corpus striatum--current developments in the memory-habit distinction
    • Gaffan D. Memory, action and the corpus striatum--current developments in the memory-habit distinction. Semin Neurosci. 1996;8: 33-38.
    • (1996) Semin Neurosci. , vol.8 , pp. 33-38
    • Gaffan, D.1
  • 122
    • 0030906428 scopus 로고    scopus 로고
    • Mnemonic functions of the basal ganglia
    • White NM. Mnemonic functions of the basal ganglia. Curr Opin Neurobiol. 1997;7: 164-169.
    • (1997) Curr Opin Neurobiol. , vol.7 , pp. 164-169
    • White, N.M.1
  • 123
    • 0037057755 scopus 로고    scopus 로고
    • Getting formal with dopamine and reward
    • Schultz W. Getting formal with dopamine and reward. Neuron. 2002;36: 241-263.
    • (2002) Neuron. , vol.36 , pp. 241-263
    • Schultz, W.1
  • 124
    • 34247469023 scopus 로고    scopus 로고
    • Dopamine-mediated regulation of corticostriatal synaptic plasticity
    • Calabresi P, Picconi B, Tozzi A, Di Filippo M. Dopamine-mediated regulation of corticostriatal synaptic plasticity. Trends Neurosci. 2007;30: 211-219.
    • (2007) Trends Neurosci. , vol.30 , pp. 211-219
    • Calabresi, P.1    Picconi, B.2    Tozzi, A.3    Di Filippo, M.4
  • 125
    • 0021995997 scopus 로고
    • Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention
    • Carli M, Evenden JL, Robbins TW. Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention. Nature. 1985;313: 679-682.
    • (1985) Nature. , vol.313 , pp. 679-682
    • Carli, M.1    Evenden, J.L.2    Robbins, T.W.3
  • 126
    • 8144229502 scopus 로고    scopus 로고
    • Deficits in a lateralised associative learning task in dopamine-depleted rats, with selective recovery by dopamine-rich transplants
    • Dowd E, Dunnett SB. Deficits in a lateralised associative learning task in dopamine-depleted rats, with selective recovery by dopamine-rich transplants. Eur J Neurosci. 2004;20: 1953-1959.
    • (2004) Eur J Neurosci. , vol.20 , pp. 1953-1959
    • Dowd, E.1    Dunnett, S.B.2
  • 127
    • 0020674685 scopus 로고
    • Nigral transplants reinnervating the dopamine-depleted neostriatum can sustain intracranial self-stimulation
    • Fray PJ, Dunnett SB, Iversen SD, Björklund A, Stenevi U. Nigral transplants reinnervating the dopamine-depleted neostriatum can sustain intracranial self-stimulation. Science. 1983;219: 416-419.
    • (1983) Science. , vol.219 , pp. 416-419
    • Fray, P.J.1    Dunnett, S.B.2    Iversen, S.D.3    Björklund, A.4    Stenevi, U.5
  • 128
    • 0024198705 scopus 로고
    • Transplant-induced recovery from 6-OHDA lesions of the nigrostriatal dopamine neurones in mice
    • Shimizu K, Tsuda N, Okamoto Y, et al. Transplant-induced recovery from 6-OHDA lesions of the nigrostriatal dopamine neurones in mice. Acta Neurochir Suppl. 1988;43: 149-153.
    • (1988) Acta Neurochir Suppl. , vol.43 , pp. 149-153
    • Shimizu, K.1    Tsuda, N.2    Okamoto, Y.3
  • 129
    • 0022633388 scopus 로고
    • The rotating 6-hydroxydopamine lesioned mouse as a model for assessing functional effects of neuronal grafting
    • Brundin P, Isacson O, Gage FH, Prochiantz A, Björklund A. The rotating 6-hydroxydopamine lesioned mouse as a model for assessing functional effects of neuronal grafting. Brain Res. 1986;366: 346-349.
    • (1986) Brain Res. , vol.366 , pp. 346-349
    • Brundin, P.1    Isacson, O.2    Gage, F.H.3    Prochiantz, A.4    Björklund, A.5
  • 130
    • 0029001585 scopus 로고
    • Transplantation of mesencephalic cell suspensions from wild-type and heterozygous weaver mice into the denervated striatum--assessing the role of graft-derived dopaminergic dendrites in the recovery of function
    • Witt TC, Triarhou LC. Transplantation of mesencephalic cell suspensions from wild-type and heterozygous weaver mice into the denervated striatum--assessing the role of graft-derived dopaminergic dendrites in the recovery of function. Cell Transplant. 1995;4: 323-333.
    • (1995) Cell Transplant. , vol.4 , pp. 323-333
    • Witt, T.C.1    Triarhou, L.C.2
  • 131
    • 0026603012 scopus 로고
    • Embryonic dopaminergic neuron transplants in MPTP lesioned mouse striatum
    • Di Porzio U, Zuddas A. Embryonic dopaminergic neuron transplants in MPTP lesioned mouse striatum. Neurochem Int. 1992;20(suppl): 309S-320S.
    • (1992) Neurochem Int. , vol.20 , Issue.SUPPL , pp. 309S-320S
    • Di Porzio, U.1    Zuddas, A.2
  • 132
    • 0025259520 scopus 로고
    • Bilateral recovery of striatal dopamine after unilateral adrenal grafting into the striatum of the 1-methyl-4-(2'methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-treated mice
    • Bohn MC, Kanuicki M. Bilateral recovery of striatal dopamine after unilateral adrenal grafting into the striatum of the 1-methyl-4-(2'methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-treated mice. J Neurosci Res. 1990;25: 281-286.
    • (1990) J Neurosci Res. , vol.25 , pp. 281-286
    • Bohn, M.C.1    Kanuicki, M.2
  • 133
    • 0023225802 scopus 로고
    • Adrenal grafts enhance recovery of striatal dopaminergic fibers
    • Bohn MC, Cupit L, Marciano F, Gash DM. Adrenal grafts enhance recovery of striatal dopaminergic fibers. Science. 1987;237: 913-916.
    • (1987) Science. , vol.237 , pp. 913-916
    • Bohn, M.C.1    Cupit, L.2    Marciano, F.3    Gash, D.M.4
  • 134
    • 41949130335 scopus 로고    scopus 로고
    • Transplantation of human amniotic cells exerts neuroprotection in MPTP-induced Parkinson disease mice
    • Kong XY, Cai Z, Pan L, et al. Transplantation of human amniotic cells exerts neuroprotection in MPTP-induced Parkinson disease mice. Brain Res. 2008;1205: 108-115.
    • (2008) Brain Res. , vol.1205 , pp. 108-115
    • Kong, X.Y.1    Cai, Z.2    Pan, L.3
  • 136
    • 0036844019 scopus 로고    scopus 로고
    • Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
    • Ourednik J, Ourednik V, Lynch WP, Schachner M, Snyder EY. Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat Biotechnol. 2002;20: 1103-1110.
    • (2002) Nat Biotechnol. , vol.20 , pp. 1103-1110
    • Ourednik, J.1    Ourednik, V.2    Lynch, W.P.3    Schachner, M.4    Snyder, E.Y.5
  • 137
    • 0035829368 scopus 로고    scopus 로고
    • Behavioral phenotyping of the MPTP mouse model of Parkinson's disease
    • Sedelis M, Schwarting RK, Huston JP. Behavioral phenotyping of the MPTP mouse model of Parkinson's disease. Behav Brain Res. 2001;125: 109-125.
    • (2001) Behav Brain Res. , vol.125 , pp. 109-125
    • Sedelis, M.1    Schwarting, R.K.2    Huston, J.P.3
  • 139
    • 0023031781 scopus 로고
    • Transplantation of ventral mesencephalic anlagen to hosts with genetic nigrostriatal dopamine deficiency
    • Triarhou LC, Low WC, Ghetti B. Transplantation of ventral mesencephalic anlagen to hosts with genetic nigrostriatal dopamine deficiency. Proc Natl Acad Sci USA. 1986;83: 8789-8793.
    • (1986) Proc Natl Acad Sci USA. , vol.83 , pp. 8789-8793
    • Triarhou, L.C.1    Low, W.C.2    Ghetti, B.3
  • 140
    • 0023951172 scopus 로고
    • Reinstatement of synaptic connectivity in the striatum of weaver mutant mice following transplantation of ventral mesencephalic anlagen
    • Triarhou LC, Low WC, Norton J, Ghetti B. Reinstatement of synaptic connectivity in the striatum of weaver mutant mice following transplantation of ventral mesencephalic anlagen. J Neurocytol. 1988;17: 233-243.
    • (1988) J Neurocytol. , vol.17 , pp. 233-243
    • Triarhou, L.C.1    Low, W.C.2    Norton, J.3    Ghetti, B.4
  • 141
    • 0029027869 scopus 로고
    • Amelioration of the behavioral phenotype in weaver mutant mice through bilateral intrastriatal grafting of fetal dopamine cells
    • Triarhou LC, Norton J, Hingtgen JN. Amelioration of the behavioral phenotype in weaver mutant mice through bilateral intrastriatal grafting of fetal dopamine cells. Exp Brain Res. 1995;104: 191-198.
    • (1995) Exp Brain Res. , vol.104 , pp. 191-198
    • Triarhou, L.C.1    Norton, J.2    Hingtgen, J.N.3
  • 142
    • 20644464349 scopus 로고    scopus 로고
    • Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts
    • Sorensen AT, Thompson L, Kirik D, Björklund A, Lindvall O, Kokaia M. Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts. Eur J Neurosci. 2005;21: 2793-2799.
    • (2005) Eur J Neurosci. , vol.21 , pp. 2793-2799
    • Sorensen, A.T.1    Thompson, L.2    Kirik, D.3    Björklund, A.4    Lindvall, O.5    Kokaia, M.6
  • 143
    • 0032515356 scopus 로고    scopus 로고
    • Use of GFAP-lacZ transgenic mice to determine astrocyte fate in grafts of embryonic ventral midbrain
    • Quintana JG, Lopez-Colberg I, Cunningham LA. Use of GFAP-lacZ transgenic mice to determine astrocyte fate in grafts of embryonic ventral midbrain. Dev Brain Res. 1998;105: 147-151.
    • (1998) Dev Brain Res. , vol.105 , pp. 147-151
    • Quintana, J.G.1    Lopez-Colberg, I.2    Cunningham, L.A.3
  • 144
    • 0028899401 scopus 로고
    • Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease
    • Nakao N, Frodl EM, Widner H, et al. Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nat Med. 1995;1: 226-231.
    • (1995) Nat Med. , vol.1 , pp. 226-231
    • Nakao, N.1    Frodl, E.M.2    Widner, H.3
  • 145
    • 48649111174 scopus 로고    scopus 로고
    • Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease
    • Hedlund E, Pruszak J, Lardaro T, et al. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem Cells. 2008;26: 1526-1536.
    • (2008) Stem Cells. , vol.26 , pp. 1526-1536
    • Hedlund, E.1    Pruszak, J.2    Lardaro, T.3
  • 146
    • 33244459813 scopus 로고    scopus 로고
    • Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia
    • Carlsson T, Winkler C, Lundblad M, Cenci MA, Björklund A, Kirik D. Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia. Neurobiol Dis. 2006;21: 657-668.
    • (2006) Neurobiol Dis. , vol.21 , pp. 657-668
    • Carlsson, T.1    Winkler, C.2    Lundblad, M.3    Cenci, M.A.4    Björklund, A.5    Kirik, D.6
  • 147
    • 33646140789 scopus 로고    scopus 로고
    • The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat
    • Lane EL, Winkler C, Brundin P, Cenci MA. The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat. Neurobiol Dis. 2006;22: 334-346.
    • (2006) Neurobiol Dis. , vol.22 , pp. 334-346
    • Lane, E.L.1    Winkler, C.2    Brundin, P.3    Cenci, M.A.4
  • 148
    • 0033932460 scopus 로고    scopus 로고
    • Embryonic ventral mesencephalic grafts improve levodopa-induced dyskinesia in a rat model of Parkinson's disease
    • Lee CS, Cenci MA, Schulzer M, Björklund A. Embryonic ventral mesencephalic grafts improve levodopa-induced dyskinesia in a rat model of Parkinson's disease. Brain. 2000;123: 1365-1379.
    • (2000) Brain. , vol.123 , pp. 1365-1379
    • Lee, C.S.1    Cenci, M.A.2    Schulzer, M.3    Björklund, A.4
  • 149
  • 150
    • 60149088032 scopus 로고    scopus 로고
    • Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration
    • Carlsson T, Carta M, Munoz A, et al. Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration. Brain 2008;132: 319-335.
    • (2008) Brain , vol.132 , pp. 319-335
    • Carlsson, T.1    Carta, M.2    Munoz, A.3
  • 151
    • 0029932534 scopus 로고    scopus 로고
    • Long-term outcome of unilaterally transplanted Parkinsonian patients. 1. Clinical approach
    • Defer GL, Gény C, Ricolfi F, et al. Long-term outcome of unilaterally transplanted Parkinsonian patients. 1. Clinical approach. Brain. 1996;119: 41-50.
    • (1996) Brain. , vol.119 , pp. 41-50
    • Defer, G.L.1    Gény, C.2    Ricolfi, F.3
  • 152
    • 0033053030 scopus 로고    scopus 로고
    • Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
    • Hauser RA, Freeman TB, Snow BJ, et al. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease. Arch Neurol. 1999;56: 179-187.
    • (1999) Arch Neurol. , vol.56 , pp. 179-187
    • Hauser, R.A.1    Freeman, T.B.2    Snow, B.J.3
  • 153
    • 0033934144 scopus 로고    scopus 로고
    • Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
    • Brundin P, Pogarell O, Hagell P, et al. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain. 2000;123: 1380-1390.
    • (2000) Brain. , vol.123 , pp. 1380-1390
    • Brundin, P.1    Pogarell, O.2    Hagell, P.3
  • 154
    • 0032692348 scopus 로고    scopus 로고
    • Sequential bilateral transplantation in Parkinson's disease--effects of the second graft
    • Hagell P, Schrag A, Piccini P, et al. Sequential bilateral transplantation in Parkinson's disease--effects of the second graft. Brain. 1999;122: 1121-1132.
    • (1999) Brain. , vol.122 , pp. 1121-1132
    • Hagell, P.1    Schrag, A.2    Piccini, P.3
  • 155
    • 0035826089 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med. 2001;344: 710-719.
    • (2001) N Engl J Med. , vol.344 , pp. 710-719
    • Freed, C.R.1    Greene, P.E.2    Breeze, R.E.3
  • 156
    • 0042837887 scopus 로고    scopus 로고
    • A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
    • Olanow CW, Goetz CG, Kordower JH, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol. 2003;54: 403-414.
    • (2003) Ann Neurol. , vol.54 , pp. 403-414
    • Olanow, C.W.1    Goetz, C.G.2    Kordower, J.H.3
  • 157
    • 67349088356 scopus 로고    scopus 로고
    • Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis
    • Olanow CW, Gracies JM, Goetz CG, et al. Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis. Mov Disord. 2009; 24: 335-343.
    • (2009) Mov Disord. , vol.24 , pp. 335-343
    • Olanow, C.W.1    Gracies, J.M.2    Goetz, C.G.3
  • 158
    • 0036830588 scopus 로고    scopus 로고
    • Dyskinesia after fetal cell transplantation for parkinsonism: a PET study
    • Ma YL, Feigin A, Dhawan V, et al. Dyskinesia after fetal cell transplantation for parkinsonism: a PET study. Ann Neurol. 2002;52: 628-634.
    • (2002) Ann Neurol. , vol.52 , pp. 628-634
    • Ma, Y.L.1    Feigin, A.2    Dhawan, V.3
  • 159
    • 29144490744 scopus 로고    scopus 로고
    • Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats
    • Maries E, Kordower JH, Chu Y, et al. Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats. Neurobiol Dis. 2006;21: 165-180.
    • (2006) Neurobiol Dis. , vol.21 , pp. 165-180
    • Maries, E.1    Kordower, J.H.2    Chu, Y.3
  • 161
    • 34547484764 scopus 로고    scopus 로고
    • Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease
    • Carlsson T, Carta M, Winkler C, Björklund A, Kirik D. Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. J Neurosci. 2007;27: 8011-8022.
    • (2007) J Neurosci. , vol.27 , pp. 8011-8022
    • Carlsson, T.1    Carta, M.2    Winkler, C.3    Björklund, A.4    Kirik, D.5
  • 162
    • 34447627504 scopus 로고    scopus 로고
    • Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats
    • Carta M, Carlsson T, Kirik D, Björklund A. Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats. Brain. 2007;130: 1819-1833.
    • (2007) Brain. , vol.130 , pp. 1819-1833
    • Carta, M.1    Carlsson, T.2    Kirik, D.3    Björklund, A.4
  • 163
    • 0021883870 scopus 로고
    • Repairing neuronal circuits with brain grafts: where can brain grafts be used as a therapy?
    • Freed WJ. Repairing neuronal circuits with brain grafts: where can brain grafts be used as a therapy? Neurobiol Aging. 1985;6: 153-156.
    • (1985) Neurobiol Aging. , vol.6 , pp. 153-156
    • Freed, W.J.1
  • 164
    • 0000837785 scopus 로고
    • Mechanisms of action of intracerebral neural implants--studies on nigral and striatal grafts to the lesioned striatum
    • Björklund A, Lindvall O, Isacson O, et al. Mechanisms of action of intracerebral neural implants--studies on nigral and striatal grafts to the lesioned striatum. Trends Neurosci. 1987;10: 509-516.
    • (1987) Trends Neurosci. , vol.10 , pp. 509-516
    • Björklund, A.1    Lindvall, O.2    Isacson, O.3
  • 165
    • 0012030574 scopus 로고
    • CNS grafting: potential mechanisms of action
    • Seil FJ, ed, New York, NY: Alan R. Liss
    • Gage FH, Buzsaki G. CNS grafting: potential mechanisms of action. In: Seil FJ, ed. Neural Regeneration and Transplantation. New York, NY: Alan R. Liss; 1989;211-226.
    • (1989) Neural Regeneration and Transplantation. , pp. 211-226
    • Gage, F.H.1    Buzsaki, G.2
  • 166
    • 80052552996 scopus 로고    scopus 로고
    • Cell replacement therapy: mechanisms of functional recovery
    • Squire LR, ed., Amsterdam, the Netherlands: Elsevier
    • Dunnett SB. Cell replacement therapy: mechanisms of functional recovery. In: Squire LR, ed. New Encyclopedia of Neuroscience. Amsterdam, the Netherlands: Elsevier; 2009; pp 643-647.
    • (2009) New Encyclopedia of Neuroscience. , pp. 643-647
    • Dunnett, S.B.1
  • 169
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • Albin RL, Young AB, Penney JB. The functional anatomy of basal ganglia disorders. Trends Neurosci. 1989;12: 366-375.
    • (1989) Trends Neurosci. , vol.12 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 170
    • 76549260621 scopus 로고
    • Surgical experiments in therapy of certain "extrapyramidal" diseases: current evaluation
    • Meyers R. Surgical experiments in therapy of certain "extrapyramidal" diseases: current evaluation. Acta Psychiatr Neurol Suppl 1951;67: 1-42.
    • (1951) Acta Psychiatr Neurol Suppl , vol.67 , pp. 1-42
    • Meyers, R.1
  • 171
    • 0032874242 scopus 로고    scopus 로고
    • Behavioral changes associated with grafts of embryonic ventral mesencephalon tissue into the striatum and/or substantia nigra in a rat model of Parkinson's disease
    • Johnston RE, Becker JB. Behavioral changes associated with grafts of embryonic ventral mesencephalon tissue into the striatum and/or substantia nigra in a rat model of Parkinson's disease. Behav Brain Res. 1999;104: 179-187.
    • (1999) Behav Brain Res. , vol.104 , pp. 179-187
    • Johnston, R.E.1    Becker, J.B.2
  • 172
    • 0024409802 scopus 로고
    • Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry
    • Forni C, Brundin P, Strecker RE, Elganouni S, Björklund A, Nieoullon A. Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry. Exp Brain Res. 1989;76: 75-87.
    • (1989) Exp Brain Res. , vol.76 , pp. 75-87
    • Forni, C.1    Brundin, P.2    Strecker, R.E.3    Elganouni, S.4    Björklund, A.5    Nieoullon, A.6
  • 173
    • 0029123177 scopus 로고
    • Long-term effects of human-to-rat mesencephalic xenografts on rotational behavior, striatal dopamine receptor binding, and mRNA levels
    • Strömberg I, Adams C, Bygdeman M, Hoffer B, Boyson S, Humpel C. Long-term effects of human-to-rat mesencephalic xenografts on rotational behavior, striatal dopamine receptor binding, and mRNA levels. Brain Res Bull. 1995;38: 221-233.
    • (1995) Brain Res Bull. , vol.38 , pp. 221-233
    • Strömberg, I.1    Adams, C.2    Bygdeman, M.3    Hoffer, B.4    Boyson, S.5    Humpel, C.6
  • 174
    • 0023755343 scopus 로고
    • Implantable microencapsulated dopamine (DA): a new approach for slow release DA delivery into brain tissue
    • McRae-Degueurce A, Hjorth S, Dillon DL, Mason DW, Tice TR. Implantable microencapsulated dopamine (DA): a new approach for slow release DA delivery into brain tissue. Neurosci Lett. 1988;92: 303-309.
    • (1988) Neurosci Lett. , vol.92 , pp. 303-309
    • McRae-Degueurce, A.1    Hjorth, S.2    Dillon, D.L.3    Mason, D.W.4    Tice, T.R.5
  • 175
    • 0019855957 scopus 로고
    • Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behavior
    • Freed WJ, Morihisa JM, Spoor E, et al. Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behavior. Nature. 1981;292: 351-352.
    • (1981) Nature. , vol.292 , pp. 351-352
    • Freed, W.J.1    Morihisa, J.M.2    Spoor, E.3
  • 176
    • 0036897235 scopus 로고    scopus 로고
    • Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease
    • Azzouz M, Martin-Rendon E, Barber RD, et al. Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease. J Neurosci. 2002;22: 10302-10312.
    • (2002) J Neurosci. , vol.22 , pp. 10302-10312
    • Azzouz, M.1    Martin-Rendon, E.2    Barber, R.D.3
  • 177
    • 0023076846 scopus 로고
    • Trophic and growth-regulating mechanisms in the central nervous system monitored by intracerebral neural transplants
    • Gage FH, Björklund A. Trophic and growth-regulating mechanisms in the central nervous system monitored by intracerebral neural transplants. Ciba Found Symp. 1987;126: 143-159.
    • (1987) Ciba Found Symp. , vol.126 , pp. 143-159
    • Gage, F.H.1    Björklund, A.2
  • 178
    • 0025217776 scopus 로고
    • Rescue of basal forebrain cholinergic neurons after implantation of genetically modified cells producing recombinant NGF
    • Strömberg I, Wetmore CJ, Ebendal T, Ernfors P, Persson H, Olson L. Rescue of basal forebrain cholinergic neurons after implantation of genetically modified cells producing recombinant NGF. J Neurosci Res. 1990;25: 405-411.
    • (1990) J Neurosci Res. , vol.25 , pp. 405-411
    • Strömberg, I.1    Wetmore, C.J.2    Ebendal, T.3    Ernfors, P.4    Persson, H.5    Olson, L.6
  • 179
    • 0031105522 scopus 로고    scopus 로고
    • Application of ex vivo gene therapy in the treatment of Parkinson's disease
    • Raymon HK, Thode S, Gage FH. Application of ex vivo gene therapy in the treatment of Parkinson's disease. Exp Neurol. 1997;144: 82-91.
    • (1997) Exp Neurol. , vol.144 , pp. 82-91
    • Raymon, H.K.1    Thode, S.2    Gage, F.H.3
  • 180
    • 0025078557 scopus 로고
    • Grafts, growth factors and grafts that make growth factors
    • Olson L, Ayer-LeLievre C, Ebendal T, et al. Grafts, growth factors and grafts that make growth factors. Prog Brain Res. 1990;82: 55-66.
    • (1990) Prog Brain Res. , vol.82 , pp. 55-66
    • Olson, L.1    Ayer-LeLievre, C.2    Ebendal, T.3
  • 181
    • 0010387233 scopus 로고
    • Neural grafts, growth factors and trophic mechanisms of recovery
    • Hunter AJ, Clarke M, eds., New York, NY: Academic Press
    • Dunnett SB, Mayer E. Neural grafts, growth factors and trophic mechanisms of recovery. In: Hunter AJ, Clarke M, eds. Neurodegeneration. New York, NY: Academic Press; 1992: 183-217.
    • (1992) Neurodegeneration. , pp. 183-217
    • Dunnett, S.B.1    Mayer, E.2
  • 182
    • 0034065380 scopus 로고    scopus 로고
    • Improving the survival of grafted dopaminergic neurons: a review over current approaches
    • Brundin P, Karlsson J, Emgård M, et al. Improving the survival of grafted dopaminergic neurons: a review over current approaches. Cell Transplant. 2000;9: 179-195.
    • (2000) Cell Transplant. , vol.9 , pp. 179-195
    • Brundin, P.1    Karlsson, J.2    Emgård, M.3
  • 183
    • 0027236053 scopus 로고
    • Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons. II. Effects on neural transplants in vivo
    • Mayer E, Fawcett JW, Dunnett SB. Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons. II. Effects on neural transplants in vivo. Neuroscience. 1993;56: 389-398.
    • (1993) Neuroscience. , vol.56 , pp. 389-398
    • Mayer, E.1    Fawcett, J.W.2    Dunnett, S.B.3
  • 184
    • 0027731592 scopus 로고
    • Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo
    • Strömberg I, Björklund L, Johansson M, et al. Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp Neurol. 1993;124: 401-412.
    • (1993) Exp Neurol. , vol.124 , pp. 401-412
    • Strömberg, I.1    Björklund, L.2    Johansson, M.3
  • 185
    • 0030298512 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts
    • Rosenblad C, Martinez-Serrano A, Björklund A. Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. Neuroscience. 1996;75: 979-985.
    • (1996) Neuroscience. , vol.75 , pp. 979-985
    • Rosenblad, C.1    Martinez-Serrano, A.2    Björklund, A.3
  • 187
    • 0033940543 scopus 로고    scopus 로고
    • Additive effects of caspase inhibitor and lazaroid on the survival of transplanted rat and human embryonic dopamine neurons
    • Hansson O, Castilho RF, Schierle GSK, et al. Additive effects of caspase inhibitor and lazaroid on the survival of transplanted rat and human embryonic dopamine neurons. Exp Neurol. 2000;164: 102-111.
    • (2000) Exp Neurol. , vol.164 , pp. 102-111
    • Hansson, O.1    Castilho, R.F.2    Schierle, G.S.K.3
  • 188
    • 0033551593 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of TGFb1 in the striatum decreases dopaminergic cell survival in embryonic nigral grafts
    • Sánchez-Capelo A, Corti O, Mallet J. Adenovirus-mediated overexpression of TGFb1 in the striatum decreases dopaminergic cell survival in embryonic nigral grafts. Neuroreport. 1999;10: 2169-2173.
    • (1999) Neuroreport. , vol.10 , pp. 2169-2173
    • Sánchez-Capelo, A.1    Corti, O.2    Mallet, J.3
  • 189
    • 0028953328 scopus 로고
    • Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease
    • Takayama H, Ray J, Raymon HK, et al. Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nat Med. 1995;1: 53-58.
    • (1995) Nat Med. , vol.1 , pp. 53-58
    • Takayama, H.1    Ray, J.2    Raymon, H.K.3
  • 190
    • 0030932056 scopus 로고    scopus 로고
    • Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase
    • Barkats M, Nakao N, Grasbon-Frodl EM, et al. Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase. Neuroscience. 1997;78: 703-713.
    • (1997) Neuroscience. , vol.78 , pp. 703-713
    • Barkats, M.1    Nakao, N.2    Grasbon-Frodl, E.M.3
  • 191
    • 0037106092 scopus 로고    scopus 로고
    • Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons
    • Ostenfeld T, Tai YT, Martin P, Déglon N, Aebischer P, Svendsen CN. Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons. J Neurosci Res. 2002;69: 955-965.
    • (2002) J Neurosci Res. , vol.69 , pp. 955-965
    • Ostenfeld, T.1    Tai, Y.T.2    Martin, P.3    Déglon, N.4    Aebischer, P.5    Svendsen, C.N.6
  • 192
    • 0035004246 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration
    • Connor B, Kozlowski DA, Unnerstall JR, et al. Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration. Exp Neurol. 2001;169: 83-95.
    • (2001) Exp Neurol. , vol.169 , pp. 83-95
    • Connor, B.1    Kozlowski, D.A.2    Unnerstall, J.R.3
  • 193
    • 0037148074 scopus 로고    scopus 로고
    • Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector
    • Georgievska B, Kirik D, Rosenblad C, Lundberg C, Björklund A. Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector. Neuroreport. 2002;13: 75-82.
    • (2002) Neuroreport. , vol.13 , pp. 75-82
    • Georgievska, B.1    Kirik, D.2    Rosenblad, C.3    Lundberg, C.4    Björklund, A.5
  • 194
    • 13144282676 scopus 로고    scopus 로고
    • Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study
    • Patel NK, Bunnage M, Plaha P, Svendsen CN, Gill SS. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann Neurol. 2005;57: 298-302.
    • (2005) Ann Neurol. , vol.57 , pp. 298-302
    • Patel, N.K.1    Bunnage, M.2    Plaha, P.3    Svendsen, C.N.4    Gill, S.S.5
  • 195
    • 85052608961 scopus 로고    scopus 로고
    • GDNF delivery for Parkinson's disease
    • Patel NK, Gill SS. GDNF delivery for Parkinson's disease. Acta Neurochir Suppl. 2007;97: 135-154.
    • (2007) Acta Neurochir Suppl. , vol.97 , pp. 135-154
    • Patel, N.K.1    Gill, S.S.2
  • 196
    • 0022648056 scopus 로고
    • Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells
    • Brundin P, Isacson O, Gage FH, Björklund A. Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells. Dev Brain Res. 1986;24: 77-84.
    • (1986) Dev Brain Res. , vol.24 , pp. 77-84
    • Brundin, P.1    Isacson, O.2    Gage, F.H.3    Björklund, A.4
  • 197
    • 0022587783 scopus 로고
    • Axon terminal clustering in nigrostriatal double grafts
    • Jaeger CB. Axon terminal clustering in nigrostriatal double grafts. Dev Brain Res. 1986;24: 309-314.
    • (1986) Dev Brain Res. , vol.24 , pp. 309-314
    • Jaeger, C.B.1
  • 198
    • 0023125859 scopus 로고
    • Embryonic substantia nigra grafts innervate embryonic striatal co-grafts in preference to mature host striatum
    • de Beaurepaire R, Freed WJ. Embryonic substantia nigra grafts innervate embryonic striatal co-grafts in preference to mature host striatum. Exp Neurol. 1987;95: 448-454.
    • (1987) Exp Neurol. , vol.95 , pp. 448-454
    • de Beaurepaire, R.1    Freed, W.J.2
  • 199
    • 0031016161 scopus 로고    scopus 로고
    • Intranigral transplants of fetal ventral mesencephalic tissue attenuate D1-agonist-induced rotational behavior
    • Yurek DM. Intranigral transplants of fetal ventral mesencephalic tissue attenuate D1-agonist-induced rotational behavior. Exp Neurol. 1997;143: 1-9.
    • (1997) Exp Neurol. , vol.143 , pp. 1-9
    • Yurek, D.M.1
  • 200
    • 0035951619 scopus 로고    scopus 로고
    • Intranigral transplantation of solid tissue ventral mesencephalon or striatal grafts induces behavioral recovery in 6-OHDA-lesioned rats
    • Palmer MR, Granholm AC, van Horne CG, et al. Intranigral transplantation of solid tissue ventral mesencephalon or striatal grafts induces behavioral recovery in 6-OHDA-lesioned rats. Brain Res. 2001;890: 86-99.
    • (2001) Brain Res. , vol.890 , pp. 86-99
    • Palmer, M.R.1    Granholm, A.C.2    van Horne, C.G.3
  • 201
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats
    • David S, Aguayo AJ. Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science. 1981;214: 931-933.
    • (1981) Science. , vol.214 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 202
    • 0031451444 scopus 로고    scopus 로고
    • Regeneration in the adult central nervous system: experimental repair strategies
    • Olson L. Regeneration in the adult central nervous system: experimental repair strategies. Nat Med. 1997;3: 1329-1335.
    • (1997) Nat Med. , vol.3 , pp. 1329-1335
    • Olson, L.1
  • 203
    • 0021138879 scopus 로고
    • Fetal mesencephalic neurons survive and extend long axons across peripheral nervous system grafts inserted into the adult rat striatum
    • Aguayo AJ, Björklund A, Stenevi U, Carlstedt T. Fetal mesencephalic neurons survive and extend long axons across peripheral nervous system grafts inserted into the adult rat striatum. Neurosci Lett. 1984;45: 53-58.
    • (1984) Neurosci Lett. , vol.45 , pp. 53-58
    • Aguayo, A.J.1    Björklund, A.2    Stenevi, U.3    Carlstedt, T.4
  • 204
    • 0022406755 scopus 로고
    • Anatomical and functional consequences of grafting mesencephalic neurons into a peripheral nerve bridge connected to the denervated striatum
    • Gage FH, Stenevi U, Carlstedt T, Foster G, Björklund A, Aguayo AJ. Anatomical and functional consequences of grafting mesencephalic neurons into a peripheral nerve bridge connected to the denervated striatum. Exp Brain Res. 1985;60: 584-589.
    • (1985) Exp Brain Res. , vol.60 , pp. 584-589
    • Gage, F.H.1    Stenevi, U.2    Carlstedt, T.3    Foster, G.4    Björklund, A.5    Aguayo, A.J.6
  • 205
    • 0029910963 scopus 로고    scopus 로고
    • Constructing a new nigrostriatal pathway in the Parkinsonian model with bridged neural transplantation in substantia nigra
    • Zhou FC, Chiang YH, Wang Y. Constructing a new nigrostriatal pathway in the Parkinsonian model with bridged neural transplantation in substantia nigra. J Neurosci. 1996;16: 6965-6974.
    • (1996) J Neurosci. , vol.16 , pp. 6965-6974
    • Zhou, F.C.1    Chiang, Y.H.2    Wang, Y.3
  • 206
    • 84918937581 scopus 로고    scopus 로고
    • Developing novel stem cell sources for transplantation in Parkinson's disease
    • Davis Sanberg C, Sanberg PR, eds., Totowa, NJ: Humana Press
    • Christophersen NS, Correia AS, Roybon L, Li JY, Brundin P. Developing novel stem cell sources for transplantation in Parkinson's disease. In: Davis Sanberg C, Sanberg PR, eds. Cell Therapy, Stem Cells, and Brain Repair. Totowa, NJ: Humana Press; 2006: 31-59.
    • (2006) Cell Therapy, Stem Cells, and Brain Repair. , pp. 31-59
    • Christophersen, N.S.1    Correia, A.S.2    Roybon, L.3    Li, J.Y.4    Brundin, P.5
  • 207
    • 0032005461 scopus 로고    scopus 로고
    • Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates
    • Espejo EF, Montoro RJ, Armengol JA, López-Barneo J. Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates. Neuron. 1998;20: 197-206.
    • (1998) Neuron. , vol.20 , pp. 197-206
    • Espejo, E.F.1    Montoro, R.J.2    Armengol, J.A.3    López-Barneo, J.4
  • 208
    • 0003057732 scopus 로고
    • Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum
    • Dunnett SB, Björklund A, eds., New York, NY: Raven Press
    • Brundin P, Duan WM, Sauer H. Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum. In: Dunnett SB, Björklund A, eds. Functional Neural Transplantation. New York, NY: Raven Press; 1994: 9-46.
    • (1994) Functional Neural Transplantation. , pp. 9-46
    • Brundin, P.1    Duan, W.M.2    Sauer, H.3
  • 209
    • 0025120490 scopus 로고
    • The clinical application of cell grafting techniques in patients with Parkinson's disease
    • Quinn NP. The clinical application of cell grafting techniques in patients with Parkinson's disease. Prog Brain Res. 1990;82: 619-625.
    • (1990) Prog Brain Res. , vol.82 , pp. 619-625
    • Quinn, N.P.1
  • 210
    • 0025935786 scopus 로고
    • United Parkinson Foundation neurotransplantation registry on adrenal medullary transplants: presurgical, and 1-year and 2-year follow-up
    • Goetz CG, Stebbins GT, Klawans HL, et al. United Parkinson Foundation neurotransplantation registry on adrenal medullary transplants: presurgical, and 1-year and 2-year follow-up. Neurology. 1991;41: 1719-1722.
    • (1991) Neurology. , vol.41 , pp. 1719-1722
    • Goetz, C.G.1    Stebbins, G.T.2    Klawans, H.L.3
  • 211
    • 0029966027 scopus 로고    scopus 로고
    • Characterization and transplantation of two neuronal cell lines with dopaminergic properties
    • Adams FS, La Rosa FG, Kumar S, et al. Characterization and transplantation of two neuronal cell lines with dopaminergic properties. Neurochem Res. 1996;21: 619-627.
    • (1996) Neurochem Res. , vol.21 , pp. 619-627
    • Adams, F.S.1    La Rosa, F.G.2    Kumar, S.3
  • 212
    • 0025119186 scopus 로고
    • In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum
    • Horellou P, Brundin P, Kalén P, Mallet J, Björklund A. In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum. Neuron. 1990;5: 393-402.
    • (1990) Neuron. , vol.5 , pp. 393-402
    • Horellou, P.1    Brundin, P.2    Kalén, P.3    Mallet, J.4    Björklund, A.5
  • 213
    • 0024371511 scopus 로고
    • Synthesis of L-3,4-dihydroxyphenylalanine by tryosine hydroxylase cDNA-transfected C6 cells: application for intracerebral grafting
    • Uchida K, Takamatsu K, Kaneda N, et al. Synthesis of L-3,4-dihydroxyphenylalanine by tryosine hydroxylase cDNA-transfected C6 cells: application for intracerebral grafting. J Neurochem. 1989;53: 728-732.
    • (1989) J Neurochem. , vol.53 , pp. 728-732
    • Uchida, K.1    Takamatsu, K.2    Kaneda, N.3
  • 214
    • 0021869116 scopus 로고
    • Immunocytochemical study of PC12 cells grafted to the brain of immature rats
    • Jaeger CB. Immunocytochemical study of PC12 cells grafted to the brain of immature rats. Exp Brain Res. 1985;59: 615-624.
    • (1985) Exp Brain Res. , vol.59 , pp. 615-624
    • Jaeger, C.B.1
  • 215
    • 0029895301 scopus 로고    scopus 로고
    • Survival and proliferation of non-neural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated with fetal allografts
    • Folkerth RD, Durso R. Survival and proliferation of non-neural tissues, with obstruction of cerebral ventricles, in a parkinsonian patient treated with fetal allografts. Neurology. 1996;46: 1219-1225.
    • (1996) Neurology. , vol.46 , pp. 1219-1225
    • Folkerth, R.D.1    Durso, R.2
  • 216
    • 0025169590 scopus 로고
    • Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
    • Bergman H, Wichmann T, DeLong MR. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science. 1990;249: 1436-1438.
    • (1990) Science. , vol.249 , pp. 1436-1438
    • Bergman, H.1    Wichmann, T.2    DeLong, M.R.3
  • 217
    • 0028796071 scopus 로고
    • Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation
    • Limousin P, Pollak P, Benazzouz A, et al. Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation. Lancet. 1995;345: 91-95.
    • (1995) Lancet. , vol.345 , pp. 91-95
    • Limousin, P.1    Pollak, P.2    Benazzouz, A.3
  • 219
    • 0035887595 scopus 로고    scopus 로고
    • Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease
    • Åkerud P, Canals JM, Snyder EY, Arenas E. Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. J Neurosci. 2001;21: 8108-8118.
    • (2001) J Neurosci. , vol.21 , pp. 8108-8118
    • Åkerud, P.1    Canals, J.M.2    Snyder, E.Y.3    Arenas, E.4
  • 220
    • 0027753815 scopus 로고
    • Trophism, transplantation, and animal models of Parkinson's disease
    • Bankiewicz KS, Mandel RJ, Sofroniew MV. Trophism, transplantation, and animal models of Parkinson's disease. Exp Neurol. 1993;124: 140-149.
    • (1993) Exp Neurol. , vol.124 , pp. 140-149
    • Bankiewicz, K.S.1    Mandel, R.J.2    Sofroniew, M.V.3
  • 221
    • 0025058215 scopus 로고
    • Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease
    • Lindvall O, Brundin P, Widner H, et al. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science. 1990;247: 574-577.
    • (1990) Science. , vol.247 , pp. 574-577
    • Lindvall, O.1    Brundin, P.2    Widner, H.3
  • 222
    • 0033370160 scopus 로고    scopus 로고
    • Fetal porcine dopaminergic cell survival in vitro and its relationship to embryonic age
    • Barker RA, Ratcliffe E, Richards A, Dunnett SB. Fetal porcine dopaminergic cell survival in vitro and its relationship to embryonic age. Cell Transplant. 1999;8: 593-599.
    • (1999) Cell Transplant. , vol.8 , pp. 593-599
    • Barker, R.A.1    Ratcliffe, E.2    Richards, A.3    Dunnett, S.B.4
  • 223
    • 17544400499 scopus 로고    scopus 로고
    • Transplantation of embryonic porcine mesencephalic tissue in patients with PD
    • Schumacher JM, Ellias SA, Palmer EP, et al. Transplantation of embryonic porcine mesencephalic tissue in patients with PD. Neurology. 2000;54: 1042-1050.
    • (2000) Neurology. , vol.54 , pp. 1042-1050
    • Schumacher, J.M.1    Ellias, S.A.2    Palmer, E.P.3
  • 224
    • 0021988433 scopus 로고
    • Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials
    • Backlund EO, Granberg PO, Hamberger B, et al. Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials. J Neurosurg. 1985;62: 169-173.
    • (1985) J Neurosurg. , vol.62 , pp. 169-173
    • Backlund, E.O.1    Granberg, P.O.2    Hamberger, B.3
  • 225
    • 0042125235 scopus 로고    scopus 로고
    • Autotransplantation of human carotid body cell aggregates for treatment of Parkinson's disease
    • Arjona V, Mínguez-Castellanos A, Montoro RJ, et al. Autotransplantation of human carotid body cell aggregates for treatment of Parkinson's disease. Neurosurgery. 2003;53: 321-328.
    • (2003) Neurosurgery. , vol.53 , pp. 321-328
    • Arjona, V.1    Mínguez-Castellanos, A.2    Montoro, R.J.3
  • 226
    • 0024326943 scopus 로고
    • Grafting fibroblasts genetically modified to produce l-DOPA in a rat model of Parkinson disease
    • Wolff JA, Fisher LJ, Xu L, et al. Grafting fibroblasts genetically modified to produce l-DOPA in a rat model of Parkinson disease. Proc Natl Acad Sci USA. 1989;86: 9011-9014.
    • (1989) Proc Natl Acad Sci USA. , vol.86 , pp. 9011-9014
    • Wolff, J.A.1    Fisher, L.J.2    Xu, L.3
  • 227
    • 0029874398 scopus 로고    scopus 로고
    • Survival and differentiation of rat and human EGF responsive precursor cells following grafting into the lesioned adult CNS
    • Svendsen CN, Clarke DJ, Rosser AE, Dunnett SB. Survival and differentiation of rat and human EGF responsive precursor cells following grafting into the lesioned adult CNS. Exp Neurol. 1996;137: 376-388.
    • (1996) Exp Neurol. , vol.137 , pp. 376-388
    • Svendsen, C.N.1    Clarke, D.J.2    Rosser, A.E.3    Dunnett, S.B.4
  • 228
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer L, Tabar V, McKay RDG. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci. 1998;1: 290-295.
    • (1998) Nat Neurosci. , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.G.3
  • 229
    • 0037133163 scopus 로고    scopus 로고
    • Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
    • Björklund L, Sánchez-Pernaute R, Chung S, et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA. 2002;99: 2344-2349.
    • (2002) Proc Natl Acad Sci USA. , vol.99 , pp. 2344-2349
    • Björklund, L.1    Sánchez-Pernaute, R.2    Chung, S.3
  • 230
    • 0037019332 scopus 로고    scopus 로고
    • Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease
    • Kim JH, Auerbach JM, Rodriguez-Gomez JA, et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature. 2002;418: 50-56.
    • (2002) Nature. , vol.418 , pp. 50-56
    • Kim, J.H.1    Auerbach, J.M.2    Rodriguez-Gomez, J.A.3
  • 231
    • 0141560443 scopus 로고    scopus 로고
    • Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats
    • Dziewczapolski G, Lie DC, Ray J, Gage FH, Shults CW. Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats. Exp Neurol. 2003;183: 653-664.
    • (2003) Exp Neurol. , vol.183 , pp. 653-664
    • Dziewczapolski, G.1    Lie, D.C.2    Ray, J.3    Gage, F.H.4    Shults, C.W.5
  • 232
    • 0041307092 scopus 로고    scopus 로고
    • Parkinson's disease mice and human umbilical cord blood
    • Ende N, Chen R. Parkinson's disease mice and human umbilical cord blood. J Med. 2002;33: 173-180.
    • (2002) J Med. , vol.33 , pp. 173-180
    • Ende, N.1    Chen, R.2
  • 233
    • 0028140614 scopus 로고
    • Transmitter release from transplants of fetal ventral mesencephalon and locus coeruleus in the rat frontal cortex and nucleus accumbens: effects of pharmacological and behavioural activating stimuli
    • Cenci MA, Kalén P, Duan WM, Björklund A. Transmitter release from transplants of fetal ventral mesencephalon and locus coeruleus in the rat frontal cortex and nucleus accumbens: effects of pharmacological and behavioural activating stimuli. Brain Res. 1994;641: 225-248.
    • (1994) Brain Res. , vol.641 , pp. 225-248
    • Cenci, M.A.1    Kalén, P.2    Duan, W.M.3    Björklund, A.4


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