-
1
-
-
0033934144
-
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
-
Brundin P, Pogarell O, Hagell P, Piccini P, Widner H, Schrag A, Kupsch A, Crabb L, Odin P, Gustavii B, Bjorklund A, Brooks DJ, Marsden CD, Oertel WH, Quinn NP, Rehncrona S, Lindvall O (2000) Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain 123:1380-1390.
-
(2000)
Brain
, vol.123
, pp. 1380-1390
-
-
Brundin, P.1
Pogarell, O.2
Hagell, P.3
Piccini, P.4
Widner, H.5
Schrag, A.6
Kupsch, A.7
Crabb, L.8
Odin, P.9
Gustavii, B.10
Bjorklund, A.11
Brooks, D.J.12
Marsden, C.D.13
Oertel, W.H.14
Quinn, N.P.15
Rehncrona, S.16
Lindvall, O.17
-
2
-
-
10744219751
-
Transplantation in Parkinson's disease: PET changes correlate with the amount of grafted tissue
-
Cochen V, Ribeiro MJ, Nguyen JP, Gurruchaga JM, Villafane G, Loc'h C, Defer G, Samson Y, Peschanski M, Hantraye P, Cesaro P, Remy P (2003) Transplantation in Parkinson's disease: PET changes correlate with the amount of grafted tissue. Mov Disord 18:928-932.
-
(2003)
Mov Disord
, vol.18
, pp. 928-932
-
-
Cochen, V.1
Ribeiro, M.J.2
Nguyen, J.P.3
Gurruchaga, J.M.4
Villafane, G.5
Loc'h, C.6
Defer, G.7
Samson, Y.8
Peschanski, M.9
Hantraye, P.10
Cesaro, P.11
Remy, P.12
-
3
-
-
0032816549
-
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
-
Damier P, Hirsch EC, Agid Y, Graybiel AM (1999) The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 122:1437-1448.
-
(1999)
Brain
, vol.122
, pp. 1437-1448
-
-
Damier, P.1
Hirsch, E.C.2
Agid, Y.3
Graybiel, A.M.4
-
4
-
-
0027082006
-
The functional role of mesotelencephalic dopamine systems
-
Dunnett SB, Robbins TW (1992) The functional role of mesotelencephalic dopamine systems. Biol Rev Camb Philos Soc 67:491-518.
-
(1992)
Biol Rev Camb Philos Soc
, vol.67
, pp. 491-518
-
-
Dunnett, S.B.1
Robbins, T.W.2
-
5
-
-
0025954066
-
Ageing and Parkinson's disease: Substantia nigra regional selectivity
-
Fearnley JM, Lees AJ (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114:2283-2301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
6
-
-
0035826089
-
Transplantation of embryonic dopamine neurons for severe Parkinson's disease
-
Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R, Dillon S, Winfield H, Culver S, Trojanowski JQ, Eidelberg D, Fahn S (2001) Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 344:710-719.
-
(2001)
N Engl J Med
, vol.344
, pp. 710-719
-
-
Freed, C.R.1
Greene, P.E.2
Breeze, R.E.3
Tsai, W.Y.4
DuMouchel, W.5
Kao, R.6
Dillon, S.7
Winfield, H.8
Culver, S.9
Trojanowski, J.Q.10
Eidelberg, D.11
Fahn, S.12
-
7
-
-
0032692348
-
Sequential bilateral transplantation in Parkinson's disease: Effects of the second graft
-
Hagell P, Schrag A, Piccini P, Jahanshahi M, Brown R, Rehncrona S, Widner H, Brundin P, Rothwell JC, Odin P, Wenning GK, Morrish P, Gustavii B, Bjorklund A, Brooks DJ, Marsden CD, Quinn NP, Lindvall O (1999) Sequential bilateral transplantation in Parkinson's disease: effects of the second graft. Brain 122:1121-1132.
-
(1999)
Brain
, vol.122
, pp. 1121-1132
-
-
Hagell, P.1
Schrag, A.2
Piccini, P.3
Jahanshahi, M.4
Brown, R.5
Rehncrona, S.6
Widner, H.7
Brundin, P.8
Rothwell, J.C.9
Odin, P.10
Wenning, G.K.11
Morrish, P.12
Gustavii, B.13
Bjorklund, A.14
Brooks, D.J.15
Marsden, C.D.16
Quinn, N.P.17
Lindvall, O.18
-
8
-
-
0033053030
-
Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
-
Hauser RA, Freeman TB, Snow BJ, Nauert M, Gauger L, Kordower JH, Olanow CW (1999) Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease. Arch Neurol 56:179-187.
-
(1999)
Arch Neurol
, vol.56
, pp. 179-187
-
-
Hauser, R.A.1
Freeman, T.B.2
Snow, B.J.3
Nauert, M.4
Gauger, L.5
Kordower, J.H.6
Olanow, C.W.7
-
9
-
-
0023740954
-
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
-
Hirsch E, Graybiel AM, Agid YA (1988) Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334:345-348.
-
(1988)
Nature
, vol.334
, pp. 345-348
-
-
Hirsch, E.1
Graybiel, A.M.2
Agid, Y.A.3
-
10
-
-
0032143368
-
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
-
Kirik D, Rosenblad C, Bjorklund A (1998) Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp Neurol 152:259-277.
-
(1998)
Exp Neurol
, vol.152
, pp. 259-277
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
-
11
-
-
0035871386
-
Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration
-
Kirik D, Winkler C, Bjorklund A (2001) Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration. J Neurosci 21:2889-2896.
-
(2001)
J Neurosci
, vol.21
, pp. 2889-2896
-
-
Kirik, D.1
Winkler, C.2
Bjorklund, A.3
-
12
-
-
0023874410
-
Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
-
Kish SJ, Shannak K, Hornykiewicz O (1988) Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med 318:876-880.
-
(1988)
N Engl J Med
, vol.318
, pp. 876-880
-
-
Kish, S.J.1
Shannak, K.2
Hornykiewicz, O.3
-
13
-
-
0028911848
-
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
-
Kordower JH, Freeman TB, Snow BJ, Vingerhoets FJ, Mufson EJ, Sanberg PR, Hauser RA, Smith DA, Nauert GM, Perl DP, Olanow CW (1995) Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med 332:1118-1124.
-
(1995)
N Engl J Med
, vol.332
, pp. 1118-1124
-
-
Kordower, J.H.1
Freeman, T.B.2
Snow, B.J.3
Vingerhoets, F.J.4
Mufson, E.J.5
Sanberg, P.R.6
Hauser, R.A.7
Smith, D.A.8
Nauert, G.M.9
Perl, D.P.10
Olanow, C.W.11
-
14
-
-
0025058215
-
Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease
-
Lindvall O, Brundin P, Widner H, Rehncrona S, Gustavii B, Frackowiak R, Leenders KL, Sawle G, Rothwell JC, Marsden CD, Bjorklund A (1990) Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 247:574-577.
-
(1990)
Science
, vol.247
, pp. 574-577
-
-
Lindvall, O.1
Brundin, P.2
Widner, H.3
Rehncrona, S.4
Gustavii, B.5
Frackowiak, R.6
Leenders, K.L.7
Sawle, G.8
Rothwell, J.C.9
Marsden, C.D.10
Bjorklund, A.11
-
15
-
-
0034099045
-
Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line-derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical considerations
-
Mendez I, Dagher A, Hong M, Hebb A, Gaudet P, Law A, Weerasinghe S, King D, Desrosiers J, Darvesh S, Acorn T, Robertson H (2000) Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line-derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical considerations. J Neurosurg 92:863-869.
-
(2000)
J Neurosurg
, vol.92
, pp. 863-869
-
-
Mendez, I.1
Dagher, A.2
Hong, M.3
Hebb, A.4
Gaudet, P.5
Law, A.6
Weerasinghe, S.7
King, D.8
Desrosiers, J.9
Darvesh, S.10
Acorn, T.11
Robertson, H.12
-
16
-
-
21944436225
-
Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease
-
Mendez I, Sanchez-Pernaute R, Cooper O, Vinuela A, Ferrari D, Bjorklund L, Dagher A, Isacson O (2005) Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain 128:1498-1510.
-
(2005)
Brain
, vol.128
, pp. 1498-1510
-
-
Mendez, I.1
Sanchez-Pernaute, R.2
Cooper, O.3
Vinuela, A.4
Ferrari, D.5
Bjorklund, L.6
Dagher, A.7
Isacson, O.8
-
17
-
-
0028360140
-
Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model
-
Nikkhah G, Bentlage C, Cunningham MG, Bjorklund A (1994) Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. J Neurosci 14:3449-3461.
-
(1994)
J Neurosci
, vol.14
, pp. 3449-3461
-
-
Nikkhah, G.1
Bentlage, C.2
Cunningham, M.G.3
Bjorklund, A.4
-
18
-
-
51249181873
-
Dopaminergic deficiency is more pronounced in putamen than in nucleus caudatus in Parkinson's disease
-
Nyberg P, Nordberg A, Wester P, Winblad B (1983) Dopaminergic deficiency is more pronounced in putamen than in nucleus caudatus in Parkinson's disease. Neurochem Pathol 1:193-202.
-
(1983)
Neurochem Pathol
, vol.1
, pp. 193-202
-
-
Nyberg, P.1
Nordberg, A.2
Wester, P.3
Winblad, B.4
-
19
-
-
0042837887
-
A doubleblind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
-
Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, Brin MF, Shannon KM, Nauert GM, Perl DP, Godbold J, Freeman TB (2003) A doubleblind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol 54:403-414.
-
(2003)
Ann Neurol
, vol.54
, pp. 403-414
-
-
Olanow, C.W.1
Goetz, C.G.2
Kordower, J.H.3
Stoessl, A.J.4
Sossi, V.5
Brin, M.F.6
Shannon, K.M.7
Nauert, G.M.8
Perl, D.P.9
Godbold, J.10
Freeman, T.B.11
-
20
-
-
0029064091
-
Forelimb akinesia in the rat Parkinson model: Differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
-
Olsson M, Nikkhah G, Bentlage C, Bjorklund A (1995) Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test. J Neurosci 15:3863-3875.
-
(1995)
J Neurosci
, vol.15
, pp. 3863-3875
-
-
Olsson, M.1
Nikkhah, G.2
Bentlage, C.3
Bjorklund, A.4
-
22
-
-
0028360518
-
Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon
-
Peschanski M, Defer G, N-'Guyen JP, Ricolfi F, Monfort JC, Remy P, Geny C, Samson Y, Hantraye P, Jeny R, Gaston A, Kéravel Y, Degos JD, Cesaro P (1994) Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon. Brain 117:487-499.
-
(1994)
Brain
, vol.117
, pp. 487-499
-
-
Peschanski, M.1
Defer, G.2
N-'Guyen, J.P.3
Ricolfi, F.4
Monfort, J.C.5
Remy, P.6
Geny, C.7
Samson, Y.8
Hantraye, P.9
Jeny, R.10
Gaston, A.11
Kéravel, Y.12
Degos, J.D.13
Cesaro, P.14
-
23
-
-
0033491121
-
Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
-
Piccini P, Brooks DJ, Bjorklund A, Gunn RN, Grasby PM, Rimoldi O, Brundin P, Hagell P, Rehncrona S, Widner H, Lindvall O (1999) Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat Neurosci 2:1137-1140.
-
(1999)
Nat Neurosci
, vol.2
, pp. 1137-1140
-
-
Piccini, P.1
Brooks, D.J.2
Bjorklund, A.3
Gunn, R.N.4
Grasby, P.M.5
Rimoldi, O.6
Brundin, P.7
Hagell, P.8
Rehncrona, S.9
Widner, H.10
Lindvall, O.11
-
24
-
-
28544441892
-
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
-
Piccini P, Pavese N, Hagell P, Reimer J, Bjorklund A, Oertel WH, Quinn NP, Brooks DJ, Lindvall O (2005) Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain 128:2977-2986.
-
(2005)
Brain
, vol.128
, pp. 2977-2986
-
-
Piccini, P.1
Pavese, N.2
Hagell, P.3
Reimer, J.4
Bjorklund, A.5
Oertel, W.H.6
Quinn, N.P.7
Brooks, D.J.8
Lindvall, O.9
-
25
-
-
0000431473
-
Intervention strategies for degeneration of dopamine neurons in parkinsonism: Optimising behavioral assessment of outcome
-
Emerich DF, Dean III RL, Sandburg PR, eds, pp, Totowa, NJ: Humana
-
Schallert T, Tillerson J (1999) Intervention strategies for degeneration of dopamine neurons in parkinsonism: optimising behavioral assessment of outcome. In: Central nervous system diseases: innovative models of CNS disease: from molecule to therapy (Emerich DF, Dean III RL, Sandburg PR, eds), pp 131-151. Totowa, NJ: Humana.
-
(1999)
Central nervous system diseases: Innovative models of CNS disease: from molecule to therapy
, pp. 131-151
-
-
Schallert, T.1
Tillerson, J.2
-
26
-
-
0026969268
-
A clinically relevant unilateral rat model of Parkinsonian akinesia
-
Schallert T, Norton D, Jones TA (1992) A clinically relevant unilateral rat model of Parkinsonian akinesia. J Neural Transpl Plast 3:332-333.
-
(1992)
J Neural Transpl Plast
, vol.3
, pp. 332-333
-
-
Schallert, T.1
Norton, D.2
Jones, T.A.3
-
27
-
-
33749514780
-
An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections
-
Torres EM, Meldrum A, Kirik D, Dunnett SB (2006) An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections. J Neurosci Methods 158:64-74.
-
(2006)
J Neurosci Methods
, vol.158
, pp. 64-74
-
-
Torres, E.M.1
Meldrum, A.2
Kirik, D.3
Dunnett, S.B.4
-
28
-
-
0014954436
-
Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system
-
Ungerstedt U, Arbuthnott G (1970) Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system. Brain Res 24:485-493.
-
(1970)
Brain Res
, vol.24
, pp. 485-493
-
-
Ungerstedt, U.1
Arbuthnott, G.2
-
29
-
-
0033083082
-
Stereological methods for estimating the total number of neurons and synapses: Issues of precision and bias
-
West MJ (1999) Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias. Trends Neurosci 22:51-61.
-
(1999)
Trends Neurosci
, vol.22
, pp. 51-61
-
-
West, M.J.1
-
30
-
-
0033054208
-
Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants
-
Winkler C, Bentlage C, Nikkhah G, Samii M, Bjorklund A (1999) Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dopaminergic transplants. Exp Neurol 155:165-186.
-
(1999)
Exp Neurol
, vol.155
, pp. 165-186
-
-
Winkler, C.1
Bentlage, C.2
Nikkhah, G.3
Samii, M.4
Bjorklund, A.5
-
31
-
-
13144259693
-
Cell transplantation in Parkinson's disease: How can we make it work?
-
Winkler C, Kirik D, Bjorklund A (2005) Cell transplantation in Parkinson's disease: how can we make it work? Trends Neurosci 28:86-92.
-
(2005)
Trends Neurosci
, vol.28
, pp. 86-92
-
-
Winkler, C.1
Kirik, D.2
Bjorklund, A.3
|