메뉴 건너뛰기




Volumn 749, Issue 2, 1997, Pages 188-199

Drug-free evaluation of rat models of parkinsonism and nigral grafts using a new automated rotarod test

Author keywords

6 hydroxydopamine lesion; behavioral test; Parkinson's disease; rotational behavior; transplantation

Indexed keywords

APOMORPHINE; DOPAMINE RECEPTOR STIMULATING AGENT; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

EID: 0031055595     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01162-6     Document Type: Article
Times cited : (104)

References (42)
  • 1
    • 0027452902 scopus 로고
    • Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: Effects on drug-induced behaviours and skilled paw-reaching
    • Abrous, D.N., Shallot, A.R.A., Torres, E.M. and Dunnett, S.B., Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching, Neuroscience, 53 (1993) 187-197.
    • (1993) Neuroscience , vol.53 , pp. 187-197
    • Abrous, D.N.1    Shallot, A.R.A.2    Torres, E.M.3    Dunnett, S.B.4
  • 3
    • 0002758838 scopus 로고
    • Parkinson's disease: Clinical features and etiopathology
    • P.J. Vinken, G.W. Bruyn and H.L. Klawans (Eds.), Elsevier, Amsterdam
    • Barbeau, A., Parkinson's disease: clinical features and etiopathology. In P.J. Vinken, G.W. Bruyn and H.L. Klawans (Eds.), Handbook of Clinical Neurology, Vol. 5 (49): Extrapyramidal Disorders, Elsevier, Amsterdam, 1986, pp. 87-15.
    • (1986) Handbook of Clinical Neurology, Vol. 5 (49): Extrapyramidal Disorders , vol.5 , Issue.49 , pp. 87-115
    • Barbeau, A.1
  • 5
    • 0029055932 scopus 로고
    • Elevated body swing test: A new behavioral parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism
    • Borlongan, C.V. and Sanberg, P.R., Elevated body swing test: a new behavioral parameter for rats with 6-hydroxydopamine-induced hemiparkinsonism, J. Neurosci., 15 (1995) 5372-5378.
    • (1995) J. Neurosci. , vol.15 , pp. 5372-5378
    • Borlongan, C.V.1    Sanberg, P.R.2
  • 6
    • 0003057732 scopus 로고
    • Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum
    • S.B. Dunnet and A. Björklund (Eds.), Raven Press, New York
    • Brundin, P., Duan, W.M. and Sauer, H., Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum. In S.B. Dunnet and A. Björklund (Eds.), Functional Neural Transplantation, Raven Press, New York, 1994, pp. 9-46.
    • (1994) Functional Neural Transplantation , pp. 9-46
    • Brundin, P.1    Duan, W.M.2    Sauer, H.3
  • 7
    • 0021954503 scopus 로고
    • Monitoring of cell viability of embryonic CNS tissue and its use as criterion for intracerebral graft survival
    • Brundin, P., Isacson, O. and Björklund, A., Monitoring of cell viability of embryonic CNS tissue and its use as criterion for intracerebral graft survival, Brain Res., 331 (1985) 251-259.
    • (1985) Brain Res. , vol.331 , pp. 251-259
    • Brundin, P.1    Isacson, O.2    Björklund, A.3
  • 8
    • 0026536649 scopus 로고
    • Dopaminergic transplants normalize amphetamine-and apomorphine-induced Fos expression in the 6-hydroxydopamine lesioned striatum
    • Cenci, M.A., Kalen, P., Mandel, R.J., Wictorin, K. and Björklund, A., Dopaminergic transplants normalize amphetamine-and apomorphine-induced Fos expression in the 6-hydroxydopamine lesioned striatum, Neuroscience, 46 (1992) 943-957.
    • (1992) Neuroscience , vol.46 , pp. 943-957
    • Cenci, M.A.1    Kalen, P.2    Mandel, R.J.3    Wictorin, K.4    Björklund, A.5
  • 9
    • 0016330069 scopus 로고
    • Effects of chronic 2g centrifugation on equilibrium behavior in the rat
    • Clark, D.L., Effects of chronic 2g centrifugation on equilibrium behavior in the rat, Behav. Biol., 12 (1974) 509-516.
    • (1974) Behav. Biol. , vol.12 , pp. 509-516
    • Clark, D.L.1
  • 10
    • 0001966999 scopus 로고
    • Pathophysiology of Parkinson's signs
    • J. Jankovic and E. Tolosa (Eds.), Williams and Wilkins, Baltimore
    • Delwaide, P.J. and Gonce, M., Pathophysiology of Parkinson's signs. In J. Jankovic and E. Tolosa (Eds.), Parkinson's Disease and Movement Disorders, Williams and Wilkins, Baltimore, 1993, pp. 77-92.
    • (1993) Parkinson's Disease and Movement Disorders , pp. 77-92
    • Delwaide, P.J.1    Gonce, M.2
  • 11
    • 70449177837 scopus 로고
    • A note on a simple apparatus for detecting neurological deficit in rats and mice
    • Dunham, N.W. and Miya, T.S., A note on a simple apparatus for detecting neurological deficit in rats and mice, J. Am. Pharma. Assoc., XLVI (1957) 208-209.
    • (1957) J. Am. Pharma. Assoc. , vol.46 , pp. 208-209
    • Dunham, N.W.1    Miya, T.S.2
  • 12
    • 0019990992 scopus 로고
    • Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum
    • Dunnett, S.B. and Iversen, S.D., Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum. Brain Res., 248 (1982) 121-127.
    • (1982) Brain Res. , vol.248 , pp. 121-127
    • Dunnett, S.B.1    Iversen, S.D.2
  • 13
    • 0023191549 scopus 로고
    • Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions
    • Dunnett, S.B., Whishaw, I.Q., Rogers, D.C. and Jones G.H., Dopamine-rich grafts ameliorate whole body motor asymmetry and sensory neglect but not independent limb use in rats with 6-hydroxydopamine lesions, Brain Res., 415 (1987) 63-78.
    • (1987) Brain Res. , vol.415 , pp. 63-78
    • Dunnett, S.B.1    Whishaw, I.Q.2    Rogers, D.C.3    Jones, G.H.4
  • 14
    • 0025912187 scopus 로고
    • Substantia nigra grafts and Parkinson's disease: From animal experiments to human therapeutic trials
    • Freed, W.J., Substantia nigra grafts and Parkinson's disease: from animal experiments to human therapeutic trials, Restor. Neural. Neurosci., 3 (1991) 109-134.
    • (1991) Restor. Neural. Neurosci. , vol.3 , pp. 109-134
    • Freed, W.J.1
  • 15
    • 0343238060 scopus 로고
    • Improvement in accuracy with practice: Effects of age and Parkinson's disease
    • Hening, W.A., Rolleri, M. and Gordon, J., Improvement in accuracy with practice: effects of age and Parkinson's disease, Soc. Neurosci. Abstr., 21 (1995) 488.12.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 48812
    • Hening, W.A.1    Gordon, J.2
  • 16
    • 0027423469 scopus 로고
    • A 16-channel automated rotometer system for reliable measurement of turning behavior in 6-hydroxydopamine lesioned and transplanted rats
    • Hudson, J.L., Levin, D.R. and Hoffer, B.J., A 16-channel automated rotometer system for reliable measurement of turning behavior in 6-hydroxydopamine lesioned and transplanted rats, Cell Transplant., 2 (1993) 507-514.
    • (1993) Cell Transplant. , vol.2 , pp. 507-514
    • Hudson, J.L.1    Levin, D.R.2    Hoffer, B.J.3
  • 17
    • 0027449341 scopus 로고
    • Correlation of apomorphine-and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats
    • Hudson, J.L., Van Horne, C.G., Stromberg, I., Brock, S., Clayton, J., Masserano, J., Hoffer, B.J. and Gerhardt G.A., Correlation of apomorphine-and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats, Brain Res., 626 (1993) 167-174.
    • (1993) Brain Res. , vol.626 , pp. 167-174
    • Hudson, J.L.1    Van Horne, C.G.2    Stromberg, I.3    Brock, S.4    Clayton, J.5    Masserano, J.6    Hoffer, B.J.7    Gerhardt, G.A.8
  • 18
    • 0027379396 scopus 로고
    • Long-term sensitization of apomorphine-induced rotation behavior in rats with dopamine deafferentation or excitotoxin lesions of the striatum
    • Klug, J.M. and Norman A.B., Long-term sensitization of apomorphine-induced rotation behavior in rats with dopamine deafferentation or excitotoxin lesions of the striatum, Pharmacol. Biochem. Behav., 46 (1993) 397-403.
    • (1993) Pharmacol. Biochem. Behav. , vol.46 , pp. 397-403
    • Klug, J.M.1    Norman, A.B.2
  • 19
    • 0030003742 scopus 로고    scopus 로고
    • Time course of striatal changes induced by 6-hydroxydopamine lesion of the nigrostriatal pathway, as studied by combined evaluation of rotational behaviour and of striatal Fos expression
    • Labandeira García, J.L., Rozas, G., López Martín, E., Liste, I. and Guerra, M.J., Time course of striatal changes induced by 6-hydroxydopamine lesion of the nigrostriatal pathway, as studied by combined evaluation of rotational behaviour and of striatal Fos expression, Exp. Brain Res., 108 (1996) 69-84.
    • (1996) Exp. Brain Res. , vol.108 , pp. 69-84
    • Labandeira García, J.L.1    Rozas, G.2    López Martín, E.3    Liste, I.4    Guerra, M.J.5
  • 20
    • 0025761794 scopus 로고
    • Development of intrastriatal striatal grafts and their afferent innervation from the host
    • Labandeira García, J.L., Wictorin, K., Cunningham, E.T. and Björklund, A., Development of intrastriatal striatal grafts and their afferent innervation from the host, Neuroscience, 42 (1991) 407-426.
    • (1991) Neuroscience , vol.42 , pp. 407-426
    • Labandeira García, J.L.1    Wictorin, K.2    Cunningham, E.T.3    Björklund, A.4
  • 21
    • 0003387428 scopus 로고
    • Assessment and measurement
    • G.M. Stern (Ed.), Chapman and Hall, London
    • Lakke, J.P.W.F., Assessment and measurement In G.M. Stern (Ed.), Parkinson's Disease, Chapman and Hall, London, 1990, pp. 467-491.
    • (1990) Parkinson's Disease , pp. 467-491
    • Lakke, J.P.W.F.1
  • 22
    • 0016343184 scopus 로고
    • Further analysis of sensory inattention following lateral hypothalamic damage in the rat
    • Marshall, J.F. and Teitelbaum, P., Further analysis of sensory inattention following lateral hypothalamic damage in the rat, J. Comp. Physiol. Psychol. 86 (1974) 375-395.
    • (1974) J. Comp. Physiol. Psychol. , vol.86 , pp. 375-395
    • Marshall, J.F.1    Teitelbaum, P.2
  • 24
    • 0027960192 scopus 로고
    • Inaccuracy and instability of sequential movements in Parkinson's disease
    • Martin, K.E., Phillips, J.G., Iansek, R. and Bradshaw, J.L., Inaccuracy and instability of sequential movements in Parkinson's disease, Exp. Brain Res., 102 (1994) 131-140.
    • (1994) Exp. Brain Res. , vol.102 , pp. 131-140
    • Martin, K.E.1    Phillips, J.G.2    Iansek, R.3    Bradshaw, J.L.4
  • 25
    • 0343238059 scopus 로고
    • Hemiparkinson rats display active support in the good limbs VS passive support in the bad limbs on a skilled reaching task of variable height
    • Miklyaeva, E.I. and Whishaw, I.O., Hemiparkinson rats display active support in the good limbs VS passive support in the bad limbs on a skilled reaching task of variable height, Soc. Neurosci. Abstr., 21 (1995) 487.20.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 48720
    • Miklyaeva, E.I.1    Whishaw, I.O.2
  • 26
    • 0026101797 scopus 로고
    • The 'staircase test': A measure of independent forelimb reaching and grasping abilities in rats
    • Montoya, C.P., Campbell, H.L., Pemberton, K.D. and Dunnett, S.B., The 'staircase test': a measure of independent forelimb reaching and grasping abilities in rats, J. Neurosci. Methods, 36 (1991) 2-3.
    • (1991) J. Neurosci. Methods , vol.36 , pp. 2-3
    • Montoya, C.P.1    Campbell, H.L.2    Pemberton, K.D.3    Dunnett, S.B.4
  • 27
    • 0027179844 scopus 로고
    • Restoration of complex sensorimotor behavior and skilled forelimb use by a modified nigral cell suspension transplantation approach in the rat Parkinson model
    • Nikkhah, G., Duan, W.M., Knappe, U., Jödicke, A. and Björklund, A., Restoration of complex sensorimotor behavior and skilled forelimb use by a modified nigral cell suspension transplantation approach in the rat Parkinson model, Neuroscience, 56 (1993) 33-43.
    • (1993) Neuroscience , vol.56 , pp. 33-43
    • Nikkhah, G.1    Duan, W.M.2    Knappe, U.3    Jödicke, A.4    Björklund, A.5
  • 29
    • 0029064091 scopus 로고
    • Forelimb akinesia in the rat Parkinson model: Differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
    • Olsson, M., Nikkhah, G., Bentlage, C. and Björklund, A., Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test, J. Neurosci., 15 (1995) 3863-3875.
    • (1995) J. Neurosci. , vol.15 , pp. 3863-3875
    • Olsson, M.1    Nikkhah, G.2    Bentlage, C.3    Björklund, A.4
  • 31
    • 0025759879 scopus 로고
    • Quantitative image analysis with densitometry for immunohistochemistry and autoradiography of receptor binding sites. Methodological considerations
    • Peretti-Renucci, R., Feurstein, C., Manbier, M., Lorimier, P., Savasta, M., Thibault, J., Mons, N. and Geffard M., Quantitative Image analysis with densitometry for immunohistochemistry and autoradiography of receptor binding sites. Methodological considerations, J. Neurosci. Res., 28 (1991) 583-600.
    • (1991) J. Neurosci. Res. , vol.28 , pp. 583-600
    • Peretti-Renucci, R.1    Feurstein, C.2    Manbier, M.3    Lorimier, P.4    Savasta, M.5    Thibault, J.6    Mons, N.7    Geffard, M.8
  • 32
    • 0029015394 scopus 로고
    • Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine
    • Przedborski, S., Levvier, M., Jiang, H., Ferreira, M., Jackson, V., Donaldson, D. and Togasaki, M., Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine, Neuroscience, 67 (1995) 631-647.
    • (1995) Neuroscience , vol.67 , pp. 631-647
    • Przedborski, S.1    Levvier, M.2    Jiang, H.3    Ferreira, M.4    Jackson, V.5    Donaldson, D.6    Togasaki, M.7
  • 33
    • 0023769265 scopus 로고
    • Disengage sensorimotor deficit following apparent recovery from unilateral dopamine depletion
    • Schallert, T. and Hall, S. Disengage sensorimotor deficit following apparent recovery from unilateral dopamine depletion, Behav. Brain. Res., 30 (1988) 15-24.
    • (1988) Behav. Brain. Res. , vol.30 , pp. 15-24
    • Schallert, T.1    Hall, S.2
  • 34
    • 0026969268 scopus 로고
    • A clinically relevant unilateral rat model of Parkinsonian akinesia
    • Schallert, T., Norton, D. and Jones, T.A., A clinically relevant unilateral rat model of Parkinsonian akinesia, J. Neural Transpl. Plast., 3 (1992) 332-333.
    • (1992) J. Neural Transpl. Plast. , vol.3 , pp. 332-333
    • Schallert, T.1    Norton, D.2    Jones, T.A.3
  • 35
    • 0021000670 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurement of dopamine synthesis and metabolism
    • Schmidt, R.H., Björklund, A., Stenevi, U., Dunnett, S.B. and Gage, F.H., Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurement of dopamine synthesis and metabolism, Acta Physiol. Scand., 522 (1983) 19-28.
    • (1983) Acta Physiol. Scand. , vol.522 , pp. 19-28
    • Schmidt, R.H.1    Björklund, A.2    Stenevi, U.3    Dunnett, S.B.4    Gage, F.H.5
  • 36
    • 0002423217 scopus 로고
    • Clinical features
    • G.M. Stern (Ed.), Chapman and Hall, London
    • Selby, G., Clinical features. In G.M. Stern (Ed.), Parkinson's Disease, Chapman and Hall, London, 1990, pp. 333-388.
    • (1990) Parkinson's Disease , pp. 333-388
    • Selby, G.1
  • 37
    • 0025231887 scopus 로고
    • Amphetamine sensitization of stress-induced turning in animals given unilateral dopamine transplants in infancy
    • Snyder-Keller, A.M. and Lund, R.D., Amphetamine sensitization of stress-induced turning in animals given unilateral dopamine transplants in infancy, Brain Res., 514 (1990) 143-146.
    • (1990) Brain Res. , vol.514 , pp. 143-146
    • Snyder-Keller, A.M.1    Lund, R.D.2
  • 38
    • 0028492688 scopus 로고
    • Physiological mechanisms and movement analysis in Parkinson's disease
    • Steg, G. and Johnels, B., Physiological mechanisms and movement analysis in Parkinson's disease, Mol. Neurobiol., 9 (1994) 143-147.
    • (1994) Mol. Neurobiol. , vol.9 , pp. 143-147
    • Steg, G.1    Johnels, B.2
  • 39
    • 0021012291 scopus 로고
    • Quantitative assessments of gait and mobility in Parkinson's disease
    • Stern, G.M., Franklyn, S.E. and Imms, F.J., Quantitative assessments of gait and mobility in Parkinson's disease, J. Neural Transm., 2 (Suppl. 19) (1983) 201-204.
    • (1983) J. Neural Transm. , vol.2 , Issue.SUPPL. 19 , pp. 201-204
    • Stern, G.M.1    Franklyn, S.E.2    Imms, F.J.3
  • 40
    • 0028054667 scopus 로고
    • Asymmetrical orientation to edges of an openfield: Modulation by striatal dopamine and relationship to motor asymmetries in the rat
    • Sullivan, R.M., Fraser, A. and Szechtman, H., Asymmetrical orientation to edges of an openfield: modulation by striatal dopamine and relationship to motor asymmetries in the rat, Brain Res., 637 (1994) 114-118.
    • (1994) Brain Res. , vol.637 , pp. 114-118
    • Sullivan, R.M.1    Fraser, A.2    Szechtman, H.3
  • 41
    • 0015184103 scopus 로고
    • Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system
    • Ungerstedt, U., Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system, Acta Physiol. Scand., Suppl. 367 (1971) 69-93.
    • (1971) Acta Physiol. Scand., Suppl. , vol.367 , pp. 69-93
    • Ungerstedt, U.1
  • 42
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt, U. and Arbuthnott, G.W. Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system, Brain Res., 24 (1970) 485-493.
    • (1970) Brain Res. , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.