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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 7, 2002, Pages 4708-4713

Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer

(7) Kirik, Deniz a Georgievska, Biljana a Burger, Corinna b,e Winkler, Christian a,c Muzyczka, Nicholas b,e Mandel, Ronald J d,e Björklund, Anders a

a LUND UNIVERSITY (Sweden)

b Department of Molecular Genetics and Microbiology ^* (United States)

c HANNOVER MEDICAL SCHOOL (Germany)

d UNIVERSITY OF FLORIDA (United States)

e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; LEVODOPA; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENERVATION; DOPAMINE RELEASE; DRUG ADMINISTRATION ROUTE; DRUG DELIVERY SYSTEM; DRUG INDUCED DISEASE; DYSKINESIA; FEMALE; GENE TRANSFER; GENETIC TRANSDUCTION; INTRASTRIATAL DRUG ADMINISTRATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; ON OFF PHENOMENON; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VIRUS RECOMBINANT;

ANIMALS; CORPUS STRIATUM; DEPENDOVIRUS; FEMALE; GENE THERAPY; GENE TRANSFER, HORIZONTAL; GTP CYCLOHYDROLASE; LEVODOPA; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE 3-MONOOXYGENASE;

ADENO-ASSOCIATED VIRUS; ANIMALIA; PARKINSONIA;

EID: 0037007106 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.062047599 Document Type: Article

Times cited : (136)

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