Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome ten (PTEN) inhibition in a mouse model of temporal lobe epilepsy

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Grande, Valentina ^a   Manassero, Giusi ^a,b   Vercelli, Alessandro ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; DIAZEPAM; DIPOTASSIUM BISPEROXO OXOVANADATE; KAINIC ACID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; NERVE PROTEIN; NEUROPROTECTIVE AGENT; NEUROTOXIN; PHOSPHOPROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTOSIS; CENTRIFUGATION; CONTROLLED STUDY; CYTOPLASM; DISEASE CLASSIFICATION; DRUG EFFICACY; ENZYME INHIBITION; EXCITOTOXICITY; HETEROZYGOSITY; HIPPOCAMPAL CA3 REGION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION; MORPHOLOGY; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN CONTENT; PROTEIN DENATURATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TEMPORAL LOBE EPILEPSY; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL DEATH; DISEASE MODEL; DRUG EFFECTS; EPILEPSY, TEMPORAL LOBE; METABOLISM; NERVE CELL; PATHOLOGY; PROTEIN TRANSPORT;

MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CA3 REGION, HIPPOCAMPAL; CELL DEATH; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; EPILEPSY, TEMPORAL LOBE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KAINIC ACID; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PHOSPHOPROTEINS; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 84918827994     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114554     Document Type: Article

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