Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis

Neurobiology of Disease

Volumn 41, Issue 1, 2011, Pages 201-208

  Sury, Matthias D ^a   Vorlet Fawer, Lorianne ^a   Agarinis, Claudia ^a   Yousefi, Shida ^a   Grandgirard, Denis ^a   Leib, Stephen L ^a   Christen, Stephan ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Inflammation; Neuronal apoptosis; PI3K Akt survival pathway

Indexed keywords

BISPEROXOVANADIUM; CEFTRIAXONE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VANADIUM DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFECT; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; PNEUMOCOCCAL MENINGITIS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MENINGITIS, PNEUMOCOCCAL; NERVE DEGENERATION; ORGANOMETALLIC COMPOUNDS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR;

EID: 78349308125     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.09.007     Document Type: Article

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