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Volumn 20, Issue 1, 2015, Pages 105-118

MicroRNAs in human glioblastoma: From bench to beside

Author keywords

Biogenesis; Glioblastoma; miRNA; Review; Signaling pathway; Therapy

Indexed keywords

MICRORNA; TUMOR MARKER;

EID: 84918812634     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/4300     Document Type: Review
Times cited : (21)

References (101)
  • 1
    • 33747790218 scopus 로고    scopus 로고
    • Epidemiology and molecular pathology of glioma
    • quiz 1 p following 516 Doi not found
    • J. A. Schwartzbaum, J. L. Fisher, K. D. Aldape and M. Wrensch: Epidemiology and molecular pathology of glioma. Nat Clin Pract Neurol 2(9), 494-503; quiz 1 p following 516 (2006) Doi not found.
    • (2006) Nat Clin Pract Neurol , vol.2 , Issue.9 , pp. 494-503
    • Schwartzbaum, J.A.1    Fisher, J.L.2    Aldape, K.D.3    Wrensch, M.4
  • 2
    • 48249125791 scopus 로고    scopus 로고
    • Malignant Gliomas in Adults
    • Doi not found
    • S. K. Patrick Y. Wen: Malignant Gliomas in Adults. N Engl J Med (359), 492-507 (2008) Doi not found.
    • (2008) N Engl J Med , Issue.359 , pp. 492-507
    • Patrick, S.K.1    Wen, Y.2
  • 3
    • 79958849271 scopus 로고    scopus 로고
    • Heterogeneity maintenance in glioblastoma: A social network
    • R. Bonavia, M. M. Inda, W. K. Cavenee and F. B. Furnari: Heterogeneity maintenance in glioblastoma: a social network. Cancer Res 71(12), 4055-60 (2011) DOI: 10.1158/0008-5472.CAN-11-0153
    • (2011) Cancer Res , vol.71 , Issue.12 , pp. 4055-4060
    • Bonavia, R.1    Inda, M.M.2    Cavenee, W.K.3    Furnari, F.B.4
  • 4
    • 77952555038 scopus 로고    scopus 로고
    • Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
    • E. G. Van Meir, C. G. Hadjipanayis, A. D. Norden, H. K. Shu, P. Y. Wen and J. J. Olson: Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 60(3), 166-93 (2010) DOI: 10.3322/caac.20069
    • (2010) CA Cancer J Clin , vol.60 , Issue.3 , pp. 166-193
    • Van Meir, E.G.1    Hadjipanayis, C.G.2    Norden, A.D.3    Shu, H.K.4    Wen, P.Y.5    Olson, J.J.6
  • 5
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • L. He and G. J. Hannon: MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5(7), 522-31 (2004) DOI: 10.1038/nrg1379
    • (2004) Nat Rev Genet , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 6
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • D. P. Bartel: MicroRNAs: target recognition and regulatory functions. Cell 136(2), 215-33 (2009) DOI: 10.1016/j.cell.2009.01.002
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 7
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D. P. Bartel: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2), 281-97 (2004) DOI: 10.1016/S0092-8674(04)00045-5
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 8
    • 25444457833 scopus 로고    scopus 로고
    • MicroRNAs: Critical regulators of development, cellular physiology and malignancy
    • J. T. Mendell: MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle 4(9), 1179-84 (2005) DOI: 10.4161/cc.4.9.2032
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1179-1184
    • Mendell, J.T.1
  • 9
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative premRNA splicing
    • E. V. Makeyev, J. Zhang, M. A. Carrasco and T. Maniatis: The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative premRNA splicing. Mol Cell 27(3), 435-48 (2007) DOI: 10.1016/j.molcel.2007.07.015
    • (2007) Mol Cell , vol.27 , Issue.3 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 11
    • 84880524382 scopus 로고    scopus 로고
    • miRNAs in development and pathogenesis of the nervous system
    • J. S. Nowak and G. Michlewski: miRNAs in development and pathogenesis of the nervous system. Biochem Soc Trans 41(4), 815-20 (2013) DOI: 10.1042/BST20130044
    • (2013) Biochem Soc Trans , vol.41 , Issue.4 , pp. 815-820
    • Nowak, J.S.1    Michlewski, G.2
  • 12
    • 73349125465 scopus 로고    scopus 로고
    • MicroRNAs in cancer: Small molecules with a huge impact
    • M. V. Iorio and C. M. Croce: MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol 27(34), 5848-56 (2009) DOI: 10.1200/JCO.2009.24.0317
    • (2009) J Clin Oncol , vol.27 , Issue.34 , pp. 5848-5856
    • Iorio, M.V.1    Croce, C.M.2
  • 13
    • 84881409958 scopus 로고    scopus 로고
    • Friend or foe: The role of microRNA in chemotherapy resistance
    • H. Li and B. B. Yang: Friend or foe: the role of microRNA in chemotherapy resistance. Acta Pharmacol Sin 34(7), 870-9 (2013) DOI: 10.1038/aps.2013.35
    • (2013) Acta Pharmacol Sin , vol.34 , Issue.7 , pp. 870-879
    • Li, H.1    Yang, B.B.2
  • 14
    • 84881481364 scopus 로고    scopus 로고
    • MicroRNAs involved in chemo- and radioresistance of high-grade gliomas
    • A. Besse, J. Sana, P. Fadrus and O. Slaby: MicroRNAs involved in chemo- and radioresistance of high-grade gliomas. Tumour Biol 34(4), 1969-78 (2013) DOI: 10.1007/s13277-013-0772-5
    • (2013) Tumour Biol , vol.34 , Issue.4 , pp. 1969-1978
    • Besse, A.1    Sana, J.2    Fadrus, P.3    Slaby, O.4
  • 15
    • 84860344943 scopus 로고    scopus 로고
    • The role of microRNAs in glioma initiation and progression
    • Y. Zhang, A. Dutta and R. Abounader: The role of microRNAs in glioma initiation and progression. Front Biosci (Landmark Ed) 17, 700-12 (2012) DOI: 10.2741/3952
    • (2012) Front Biosci (Landmark Ed) , vol.17 , pp. 700-712
    • Zhang, Y.1    Dutta, A.2    Abounader, R.3
  • 16
    • 84866554223 scopus 로고    scopus 로고
    • Role of microRNAs in gliomagenesis: Targeting miRNAs in glioblastoma multiforme therapy
    • A. Nikaki, C. Piperi and A. G. Papavassiliou: Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy. Expert Opin Investig Drugs 21(10), 1475-88 (2012) DOI: 10.1517/13543784.2012.710199
    • (2012) Expert Opin Investig Drugs , vol.21 , Issue.10 , pp. 1475-1488
    • Nikaki, A.1    Piperi, C.2    Papavassiliou, A.G.3
  • 17
    • 33846188098 scopus 로고    scopus 로고
    • microRNAs as oncogenes and tumor suppressors
    • B. Zhang, X. Pan, G. P. Cobb and T. A. Anderson: microRNAs as oncogenes and tumor suppressors. Dev Biol 302(1), 1-12 (2007) DOI: 10.1016/j.ydbio.2006.08.028
    • (2007) Dev Biol , vol.302 , Issue.1 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 18
    • 22144461002 scopus 로고    scopus 로고
    • miRNAs, cancer, and stem cell division
    • C. M. Croce and G. A. Calin: miRNAs, cancer, and stem cell division. Cell 122(1), 6-7 (2005) DOI: 10.1016/j.cell.2005.06.036
    • (2005) Cell , vol.122 , Issue.1 , pp. 6-7
    • Croce, C.M.1    Calin, G.A.2
  • 19
    • 80052996141 scopus 로고    scopus 로고
    • Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants
    • J. S. Yang and E. C. Lai: Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Mol Cell 43(6), 892-903 (2011) DOI: 10.1016/j.molcel.2011.07.024
    • (2011) Mol Cell , vol.43 , Issue.6 , pp. 892-903
    • Yang, J.S.1    Lai, E.C.2
  • 20
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: MicroRNA biogenesis pathways and their regulation
    • J. Winter, S. Jung, S. Keller, R. I. Gregory and S. Diederichs: Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 11(3), 228-34 (2009) DOI: 10.1038/ncb0309-228
    • (2009) Nat Cell Biol , vol.11 , Issue.3 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederichs, S.5
  • 21
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • R. Yi, Y. Qin, I. G. Macara and B. R. Cullen: Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17(24), 3011-6 (2003) DOI: 10.1101/gad.1158803
    • (2003) Genes Dev , vol.17 , Issue.24 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 22
    • 79952199115 scopus 로고    scopus 로고
    • MicroRNA biogenesis and cancer
    • J. Winter and S. Diederichs: MicroRNA biogenesis and cancer. Methods Mol Biol 676, 3-22 (2011) DOI: 10.1007/978-1-60761-863-8-1
    • (2011) Methods Mol Biol , vol.676 , pp. 3-22
    • Winter, J.1    Diederichs, S.2
  • 24
    • 84878595514 scopus 로고    scopus 로고
    • Control of metastatic progression by microRNA regulatory networks
    • N. Pencheva and S. F. Tavazoie: Control of metastatic progression by microRNA regulatory networks. Nat Cell Biol 15(6), 546-54 (2013) DOI: 10.1038/ncb2769
    • (2013) Nat Cell Biol , vol.15 , Issue.6 , pp. 546-554
    • Pencheva, N.1    Tavazoie, S.F.2
  • 25
    • 84874629159 scopus 로고    scopus 로고
    • Hypoxia-regulated microRNAs in human cancer
    • G. Shen, X. Li, Y. F. Jia, G. A. Piazza and Y. Xi: Hypoxia-regulated microRNAs in human cancer. Acta Pharmacol Sin 34(3), 336-41 (2013) DOI: 10.1038/aps.2012.195
    • (2013) Acta Pharmacol Sin , vol.34 , Issue.3 , pp. 336-341
    • Shen, G.1    Li, X.2    Jia, Y.F.3    Piazza, G.A.4    Xi, Y.5
  • 26
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • N. Cancer Genome Atlas Research: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455(7216), 1061-8 (2008) DOI: 10.1038/nature07385
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 27
    • 84868661333 scopus 로고    scopus 로고
    • Current Progress on Understanding MicroRNAs in Glioblastoma Multiforme
    • M. Karsy, E. Arslan and F. Moy: Current Progress on Understanding MicroRNAs in Glioblastoma Multiforme. Genes Cancer 3(1), 3-15 (2012) DOI: 10.1177/1947601912448068
    • (2012) Genes Cancer , vol.3 , Issue.1 , pp. 3-15
    • Karsy, M.1    Arslan, E.2    Moy, F.3
  • 28
    • 67649202155 scopus 로고    scopus 로고
    • MicroRNA involvement in glioblastoma pathogenesis
    • J. Novakova, O. Slaby, R. Vyzula and J. Michalek: MicroRNA involvement in glioblastoma pathogenesis. Biochem Biophys Res Commun 386(1), 1-5 (2009) DOI: 10.1016/j.bbrc.2009.06.034
    • (2009) Biochem Biophys Res Commun , vol.386 , Issue.1 , pp. 1-5
    • Novakova, J.1    Slaby, O.2    Vyzula, R.3    Michalek, J.4
  • 29
    • 34447343798 scopus 로고    scopus 로고
    • Lessons learned in the development of targeted therapy for malignant gliomas
    • A. M. Omuro, S. Faivre and E. Raymond: Lessons learned in the development of targeted therapy for malignant gliomas. Mol Cancer Ther 6(7), 1909-19 (2007) DOI: 10.1158/1535-7163.MCT-07-0047
    • (2007) Mol Cancer Ther , vol.6 , Issue.7 , pp. 1909-1919
    • Omuro, A.M.1    Faivre, S.2    Raymond, E.3
  • 30
    • 84862895654 scopus 로고    scopus 로고
    • Current clinical development of PI3K pathway inhibitors in glioblastoma
    • P. Y. Wen, E. Q. Lee, D. A. Reardon, K. L. Ligon and W. K. Alfred Yung: Current clinical development of PI3K pathway inhibitors in glioblastoma. Neuro Oncol 14(7), 819-29 (2012) DOI: 10.1093/neuonc/nos117
    • (2012) Neuro Oncol , vol.14 , Issue.7 , pp. 819-829
    • Wen, P.Y.1    Lee, E.Q.2    Reardon, D.A.3    Ligon, K.L.4    Alfred Yung, W.K.5
  • 31
    • 77954341696 scopus 로고    scopus 로고
    • Survival signalling and apoptosis resistance in glioblastomas: Opportunities for targeted therapeutics
    • C. Krakstad and M. Chekenya: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics. Mol Cancer 9, 135 (2010) DOI: 10.1186/1476-4598-9-135
    • (2010) Mol Cancer , vol.9 , pp. 135
    • Krakstad, C.1    Chekenya, M.2
  • 32
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • J. A. Chan, A. M. Krichevsky and K. S. Kosik: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65(14), 6029-33 (2005) DOI: 10.1158/0008-5472.CAN-05-0137
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 33
    • 75949106927 scopus 로고    scopus 로고
    • Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status
    • X. Zhou, Y. Ren, L. Moore, M. Mei, Y. You, P. Xu, B. Wang, G. Wang, Z. Jia, P. Pu, W. Zhang and C. Kang: Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Invest 90(2), 144-55 (2010) DOI: 10.1038/labinvest.2009.126
    • (2010) Lab Invest , vol.90 , Issue.2 , pp. 144-155
    • Zhou, X.1    Ren, Y.2    Moore, L.3    Mei, M.4    You, Y.5    Xu, P.6    Wang, B.7    Wang, G.8    Jia, Z.9    Pu, P.10    Zhang, W.11    Kang, C.12
  • 34
    • 77349125856 scopus 로고    scopus 로고
    • MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol
    • Y. Ren, X. Zhou, M. Mei, X. B. Yuan, L. Han, G. X. Wang, Z. F. Jia, P. Xu, P. Y. Pu and C. S. Kang: MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol. BMC Cancer 10, 27 (2010) DOI: 10.1186/1471-2407-10-27
    • (2010) BMC Cancer , vol.10 , pp. 27
    • Ren, Y.1    Zhou, X.2    Mei, M.3    Yuan, X.B.4    Han, L.5    Wang, G.X.6    Jia, Z.F.7    Xu, P.8    Pu, P.Y.9    Kang, C.S.10
  • 36
    • 84872866274 scopus 로고    scopus 로고
    • MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells
    • Doi not found
    • Y. Lu, M. Chopp, X. Zheng, M. Katakowski, B. Buller and F. Jiang: MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells. Oncol Rep 29(1), 67-72 (2013) Doi not found.
    • (2013) Oncol Rep , vol.29 , Issue.1 , pp. 67-72
    • Lu, Y.1    Chopp, M.2    Zheng, X.3    Katakowski, M.4    Buller, B.5    Jiang, F.6
  • 38
    • 43949092082 scopus 로고    scopus 로고
    • Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion
    • X. Zheng, F. Jiang, M. Katakowski, X. Zhang, H. Jiang, Z. G. Zhang and M. Chopp: Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion. Cancer Lett 265(2), 177-87 (2008) DOI: 10.1016/j.canlet.2008.02.023
    • (2008) Cancer Lett , vol.265 , Issue.2 , pp. 177-187
    • Zheng, X.1    Jiang, F.2    Katakowski, M.3    Zhang, X.4    Jiang, H.5    Zhang, Z.G.6    Chopp, M.7
  • 39
    • 84855225471 scopus 로고    scopus 로고
    • ADAM17 promotes glioma cell malignant phenotype
    • X. Zheng, F. Jiang, M. Katakowski, Y. Lu and M. Chopp: ADAM17 promotes glioma cell malignant phenotype. Mol Carcinog 51(2), 150-64 (2012) DOI: 10.1002/mc.20772
    • (2012) Mol Carcinog , vol.51 , Issue.2 , pp. 150-164
    • Zheng, X.1    Jiang, F.2    Katakowski, M.3    Lu, Y.4    Chopp, M.5
  • 40
    • 0141753981 scopus 로고    scopus 로고
    • MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
    • J. Boudeau, A. F. Baas, M. Deak, N. A. Morrice, A. Kieloch, M. Schutkowski, A. R. Prescott, H. C. Clevers and D. R. Alessi: MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J 22(19), 5102-5114 (2003) DOI: 10.1093/emboj/cdg490
    • (2003) EMBO J , vol.22 , Issue.19 , pp. 5102-5114
    • Boudeau, J.1    Baas, A.F.2    Deak, M.3    Morrice, N.A.4    Kieloch, A.5    Schutkowski, M.6    Prescott, A.R.7    Clevers, H.C.8    Alessi, D.R.9
  • 41
    • 1842581909 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network
    • M. Brajenovic, G. Joberty, B. Kuster, T. Bouwmeester and G. Drewes: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. J Biol Chem 279(13), 12804-11 (2004) DOI: 10.1074/jbc.M312171200
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12804-12811
    • Brajenovic, M.1    Joberty, G.2    Kuster, B.3    Bouwmeester, T.4    Drewes, G.5
  • 42
    • 0038614742 scopus 로고    scopus 로고
    • Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD
    • A. F. Baas, J. Boudeau, G. P. Sapkota, L. Smit, R. Medema, N. A. Morrice, D. R. Alessi and H. C. Clevers: Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. EMBO J 22(12), 3062-72 (2003) DOI: 10.1093/emboj/cdg292
    • (2003) EMBO J , vol.22 , Issue.12 , pp. 3062-3072
    • Baas, A.F.1    Boudeau, J.2    Sapkota, G.P.3    Smit, L.4    Medema, R.5    Morrice, N.A.6    Alessi, D.R.7    Clevers, H.C.8
  • 43
    • 84863392564 scopus 로고    scopus 로고
    • MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma
    • Doi not found
    • Y. Tian, Y. Nan, L. Han, A. Zhang, G. Wang, Z. Jia, J. Hao, P. Pu, Y. Zhong and C. Kang: MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma. Int J Oncol 40(4), 1105-12 (2012) Doi not found.
    • (2012) Int J Oncol , vol.40 , Issue.4 , pp. 1105-1112
    • Tian, Y.1    Nan, Y.2    Han, L.3    Zhang, A.4    Wang, G.5    Jia, Z.6    Hao, J.7    Pu, P.8    Zhong, Y.9    Kang, C.10
  • 45
    • 45549089973 scopus 로고    scopus 로고
    • microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma
    • B. Kefas, J. Godlewski, L. Comeau, Y. Li, R. Abounader, M. Hawkinson, J. Lee, H. Fine, E. A. Chiocca, S. Lawler and B. Purow: microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 68(10), 3566-72 (2008) DOI: 10.1158/0008-5472.CAN-07-6639
    • (2008) Cancer Res , vol.68 , Issue.10 , pp. 3566-3572
    • Kefas, B.1    Godlewski, J.2    Comeau, L.3    Li, Y.4    Abounader, R.5    Hawkinson, M.6    Lee, J.7    Fine, H.8    Chiocca, E.A.9    Lawler, S.10    Purow, B.11
  • 46
    • 70449711757 scopus 로고    scopus 로고
    • Genetic alterations and signaling pathways in the evolution of gliomas
    • P. Ohgaki H Fau - Kleihues and P. Kleihues: Genetic alterations and signaling pathways in the evolution of gliomas. Cancer Sci 100(12), 2235-2241 (2009) DOI: 10.1111/j.1349-7006.2009.01308.x
    • (2009) Cancer Sci , vol.100 , Issue.12 , pp. 2235-2241
    • Ohgaki, P.1    Fau - Kleihues, H.2    Kleihues, P.3
  • 47
    • 84860790212 scopus 로고    scopus 로고
    • Review: Molecular pathology in adult high-grade gliomas: From molecular diagnostics to target therapies
    • T. F. Masui K Fau - Cloughesy, P. S. Cloughesy Tf Fau - Mischel and P. S. Mischel: Review: molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies. Neuropathol Appl Neurobiol 38(3): 271-91 (2012) DOI: 10.1111/j.1365-2990.2011.01238.x
    • (2012) Neuropathol Appl Neurobiol , vol.38 , Issue.3 , pp. 271-291
    • Masui, T.F.1    Fau - Cloughesy, K.2    Cloughesy, P.S.3    Fau - Mischel, T.4    Mischel, P.S.5
  • 48
    • 84873057852 scopus 로고    scopus 로고
    • P53-induced microRNA-107 inhibits proliferation of glioma cells and down-regulates the expression of CDK6 and Notch-2
    • L. Chen, R. Zhang, P. Li, Y. Liu, K. Qin, Z. Q. Fa, Y. J. Liu, Y. Q. Ke and X. D. Jiang: P53-induced microRNA-107 inhibits proliferation of glioma cells and down-regulates the expression of CDK6 and Notch-2. Neurosci Lett 534, 327-32 (2013) DOI: 10.1016/j.neulet.2012.11.047
    • (2013) Neurosci Lett , vol.534 , pp. 327-332
    • Chen, L.1    Zhang, R.2    Li, P.3    Liu, Y.4    Qin, K.5    Fa, Z.Q.6    Liu, Y.J.7    Ke, Y.Q.8    Jiang, X.D.9
  • 49
    • 2442495498 scopus 로고    scopus 로고
    • Development of novel targeted therapies in the treatment of malignant glioma
    • J. N. Rich and D. D. Bigner: Development of novel targeted therapies in the treatment of malignant glioma. Nat Rev Drug Discov 3(5), 430-46 (2004) DOI: 10.1038/nrd1380
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.5 , pp. 430-446
    • Rich, J.N.1    Bigner, D.D.2
  • 51
    • 84871617507 scopus 로고    scopus 로고
    • Diagnostic and therapeutic avenues for glioblastoma: No longer a dead end?
    • S. Tanaka, D. N. Louis, W. T. Curry, T. T. Batchelor and J. Dietrich: Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end? Nat Rev Clin Oncol 10(1), 14-26 (2013) DOI: 10.1038/nrclinonc.2012.204
    • (2013) Nat Rev Clin Oncol , vol.10 , Issue.1 , pp. 14-26
    • Tanaka, S.1    Louis, D.N.2    Curry, W.T.3    Batchelor, T.T.4    Dietrich, J.5
  • 52
    • 0028123442 scopus 로고
    • The p53 gene and protein in human brain tumors
    • D. N. Louis: The p53 gene and protein in human brain tumors. J Neuropathol Exp Neurol 53(1), 11-21 (1994) DOI: 10.1097/00005072-199401000-00002
    • (1994) J Neuropathol Exp Neurol , vol.53 , Issue.1 , pp. 11-21
    • Louis, D.N.1
  • 53
    • 77952778499 scopus 로고    scopus 로고
    • MicroRNA-34a: A novel tumor suppressor in p53-mutant glioma cell line U251
    • S. Luan, L. Sun and F. Huang: MicroRNA-34a: a novel tumor suppressor in p53-mutant glioma cell line U251. Arch Med Res 41(2), 67-74 (2010) DOI: 10.1016/j.arcmed.2010.02.007
    • (2010) Arch Med Res , vol.41 , Issue.2 , pp. 67-74
    • Luan, S.1    Sun, L.2    Huang, F.3
  • 57
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • T. Papagiannakopoulos, A. Shapiro and K. S. Kosik: MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 68(19), 8164-72 (2008) DOI: 10.1158/0008-5472.CAN-08-1305
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 58
    • 70349437076 scopus 로고    scopus 로고
    • p53 and E2f: Partners in life and death
    • S. Polager and D. Ginsberg: p53 and E2f: partners in life and death. Nat Rev Cancer 9(10), 738-48 (2009) DOI: 10.1038/nrc2718
    • (2009) Nat Rev Cancer , vol.9 , Issue.10 , pp. 738-748
    • Polager, S.1    Ginsberg, D.2
  • 59
    • 84873871667 scopus 로고    scopus 로고
    • MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1
    • W. Hui, L. Yuntao, L. Lun, L. WenSheng, L. ChaoFeng, H. HaiYong and B. Yueyang: MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1. PLoS One 8(1), e54932 (2013) DOI: 10.1371/journal.pone.0054932
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e54932
    • Hui, W.1    Yuntao, L.2    Lun, L.3    WenSheng, L.4    ChaoFeng, L.5    HaiYong, H.6    Yueyang, B.7
  • 60
    • 0032924467 scopus 로고    scopus 로고
    • Cyclins and cell cycle checkpoints
    • D. G. Johnson and C. L. Walker: Cyclins and cell cycle checkpoints. Annu Rev Pharmacol Toxicol 39, 295-312 (1999) DOI: 10.1146/annurev.pharmtox.39.1.295
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 295-312
    • Johnson, D.G.1    Walker, C.L.2
  • 61
    • 33644830944 scopus 로고    scopus 로고
    • Targeting the cell cycle: A new approach to cancer therapy
    • G. K. Schwartz and M. A. Shah: Targeting the cell cycle: a new approach to cancer therapy. J Clin Oncol 23(36), 9408-21 (2005) DOI: 10.1200/JCO.2005.01.5594
    • (2005) J Clin Oncol , vol.23 , Issue.36 , pp. 9408-9421
    • Schwartz, G.K.1    Shah, M.A.2
  • 62
    • 84883821549 scopus 로고    scopus 로고
    • Down-regulation of miR-106b suppresses the growth of human glioma cells
    • A. Zhang, J. Hao, K. Wang, Q. Huang, K. Yu, C. Kang, G. Wang, Z. Jia, L. Han and P. Pu: Down-regulation of miR-106b suppresses the growth of human glioma cells. J Neurooncol 112(2), 179-89 (2013) DOI: 10.1007/s11060-013-1061-2
    • (2013) J Neurooncol , vol.112 , Issue.2 , pp. 179-189
    • Zhang, A.1    Hao, J.2    Wang, K.3    Huang, Q.4    Yu, K.5    Kang, C.6    Wang, G.7    Jia, Z.8    Han, L.9    Pu, P.10
  • 64
    • 84879567465 scopus 로고    scopus 로고
    • Suppression of tumorigenicity by microRNA-138 through inhibition of EZH2-CDK4/6-pRb-E2F1 signal loop in glioblastoma multiforme
    • S. Qiu, D. Huang, D. Yin, F. Li, X. Li, H. F. Kung and Y. Peng: Suppression of tumorigenicity by microRNA-138 through inhibition of EZH2-CDK4/6-pRb-E2F1 signal loop in glioblastoma multiforme. Biochim Biophys Acta 1832(10), 1697-707 (2013) DOI: 10.1016/j.bbadis.2013.05.015
    • (2013) Biochim Biophys Acta , vol.1832 , Issue.10 , pp. 1697-1707
    • Qiu, S.1    Huang, D.2    Yin, D.3    Li, F.4    Li, X.5    Kung, H.F.6    Peng, Y.7
  • 65
    • 79952947661 scopus 로고    scopus 로고
    • Molecular heterogeneity in glioblastoma: Therapeutic opportunities and challenges
    • M. K. Nicholas, R. V. Lukas, S. Chmura, B. Yamini, M. Lesniak and P. Pytel: Molecular heterogeneity in glioblastoma: therapeutic opportunities and challenges. Semin Oncol 38(2), 243-53 (2011) DOI: 10.1053/j.seminoncol.2011.01.009
    • (2011) Semin Oncol , vol.38 , Issue.2 , pp. 243-253
    • Nicholas, M.K.1    Lukas, R.V.2    Chmura, S.3    Yamini, B.4    Lesniak, M.5    Pytel, P.6
  • 67
    • 84889030815 scopus 로고    scopus 로고
    • Increased expression of microRNA-9 predicts an unfavorable prognosis in human glioma
    • Z. Wu, L. Wang, G. Li, H. Liu, F. Fan, Z. Li, Y. Li and G. Gao: Increased expression of microRNA-9 predicts an unfavorable prognosis in human glioma. Mol Cell Biochem 384(1-2), 263-8 (2013) DOI: 10.1007/s11010-013-1805-5
    • (2013) Mol Cell Biochem , vol.384 , Issue.1-2 , pp. 263-268
    • Wu, Z.1    Wang, L.2    Li, G.3    Liu, H.4    Fan, F.5    Li, Z.6    Li, Y.7    Gao, G.8
  • 68
    • 84871366196 scopus 로고    scopus 로고
    • Increased expression of microRNA-17 predicts poor prognosis in human glioma
    • S. Lu, S. Wang, S. Geng, S. Ma, Z. Liang and B. Jiao: Increased expression of microRNA-17 predicts poor prognosis in human glioma. J Biomed Biotechnol 2012, 970761 (2012) DOI: 10.1155/2012/970761
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 970761
    • Lu, S.1    Wang, S.2    Geng, S.3    Ma, S.4    Liang, Z.5    Jiao, B.6
  • 69
    • 77954579109 scopus 로고    scopus 로고
    • miR-182 as a prognostic marker for glioma progression and patient survival
    • L. Jiang, P. Mao, L. Song, J. Wu, J. Huang, C. Lin, J. Yuan, L. Qu, S. Y. Cheng and J. Li: miR-182 as a prognostic marker for glioma progression and patient survival. Am J Pathol 177(1), 29-38 (2010) DOI: 10.2353/ajpath.2010.090812
    • (2010) Am J Pathol , vol.177 , Issue.1 , pp. 29-38
    • Jiang, L.1    Mao, P.2    Song, L.3    Wu, J.4    Huang, J.5    Lin, C.6    Yuan, J.7    Qu, L.8    Cheng, S.Y.9    Li, J.10
  • 70
    • 84879797916 scopus 로고    scopus 로고
    • Upregulation of microRNA-224 confers a poor prognosis in glioma patients
    • S. Lu, S. Wang, S. Geng, S. Ma, Z. Liang and B. Jiao: Upregulation of microRNA-224 confers a poor prognosis in glioma patients. Clin Transl Oncol 15(7), 569-74 (2013) DOI: 10.1007/s12094-012-0972-2
    • (2013) Clin Transl Oncol , vol.15 , Issue.7 , pp. 569-574
    • Lu, S.1    Wang, S.2    Geng, S.3    Ma, S.4    Liang, Z.5    Jiao, B.6
  • 72
    • 84871945711 scopus 로고    scopus 로고
    • Correlation of microRNA-372 upregulation with poor prognosis in human glioma
    • G. Li, Z. Zhang, Y. Tu, T. Jin, H. Liang, G. Cui, S. He and G. Gao: Correlation of microRNA-372 upregulation with poor prognosis in human glioma. Diagn Pathol 8, 1 (2013) DOI: 10.1186/1746-1596-8-1
    • (2013) Diagn Pathol , vol.8 , pp. 1
    • Li, G.1    Zhang, Z.2    Tu, Y.3    Jin, T.4    Liang, H.5    Cui, G.6    He, S.7    Gao, G.8
  • 73
    • 84890308961 scopus 로고    scopus 로고
    • MicroRNA-650 expression in glioma is associated with prognosis of patients
    • B. Sun, B. Pu, D. Chu, X. Chu, W. Li and D. Wei: MicroRNA-650 expression in glioma is associated with prognosis of patients. J Neurooncol 115(3), 375-80 (2013) DOI: 10.1007/s11060-013-1243-y
    • (2013) J Neurooncol , vol.115 , Issue.3 , pp. 375-380
    • Sun, B.1    Pu, B.2    Chu, D.3    Chu, X.4    Li, W.5    Wei, D.6
  • 74
    • 84880277772 scopus 로고    scopus 로고
    • MicroRNA-203 down-regulation is associated with unfavorable prognosis in human glioma
    • J. He, Y. Deng, G. Yang and W. Xie: MicroRNA-203 down-regulation is associated with unfavorable prognosis in human glioma. J Surg Oncol 108(2), 121-5 (2013) DOI: 10.1002/jso.23315
    • (2013) J Surg Oncol , vol.108 , Issue.2 , pp. 121-125
    • He, J.1    Deng, Y.2    Yang, G.3    Xie, W.4
  • 75
    • 84870402500 scopus 로고    scopus 로고
    • Correlation of microRNA-375 downregulation with unfavorable clinical outcome of patients with glioma
    • C. Chang, H. Shi, C. Wang, J. Wang, N. Geng, X. Jiang and X. Wang: Correlation of microRNA-375 downregulation with unfavorable clinical outcome of patients with glioma. Neurosci Lett 531(2), 204-8 (2012) DOI: 10.1016/j.neulet.2012.10.021
    • (2012) Neurosci Lett , vol.531 , Issue.2 , pp. 204-208
    • Chang, C.1    Shi, H.2    Wang, C.3    Wang, J.4    Geng, N.5    Jiang, X.6    Wang, X.7
  • 76
    • 84867433208 scopus 로고    scopus 로고
    • MiR-328 expression is decreased in high-grade gliomas and is associated with worse survival in primary glioblastoma
    • Z. Wu, L. Sun, H. Wang, J. Yao, C. Jiang, W. Xu and Z. Yang: MiR-328 expression is decreased in high-grade gliomas and is associated with worse survival in primary glioblastoma. PLoS One 7(10), e47270 (2012) DOI: 10.1371/journal.pone.0047270
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e47270
    • Wu, Z.1    Sun, L.2    Wang, H.3    Yao, J.4    Jiang, C.5    Xu, W.6    Yang, Z.7
  • 78
    • 81855192731 scopus 로고    scopus 로고
    • MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients
    • R. Lakomy, J. Sana, S. Hankeova, P. Fadrus, L. Kren, E. Lzicarova, M. Svoboda, H. Dolezelova, M. Smrcka, R. Vyzula, J. Michalek, M. Hajduch and O. Slaby: MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients. Cancer Sci 102(12), 2186-90 (2011) DOI: 10.1111/j.1349-7006.2011.02092.x
    • (2011) Cancer Sci , vol.102 , Issue.12 , pp. 2186-2190
    • Lakomy, R.1    Sana, J.2    Hankeova, S.3    Fadrus, P.4    Kren, L.5    Lzicarova, E.6    Svoboda, M.7    Dolezelova, H.8    Smrcka, M.9    Vyzula, R.10    Michalek, J.11    Hajduch, M.12    Slaby, O.13
  • 79
    • 84873342453 scopus 로고    scopus 로고
    • Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme
    • W. Zhang, J. Zhang, W. Yan, G. You, Z. Bao, S. Li, C. Kang, C. Jiang, Y. You, Y. Zhang, C. C. Chen, S. W. Song and T. Jiang: Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme. Cancer 119(4), 814-24 (2013) DOI: 10.1002/cncr.27826
    • (2013) Cancer , vol.119 , Issue.4 , pp. 814-824
    • Zhang, W.1    Zhang, J.2    Yan, W.3    You, G.4    Bao, Z.5    Li, S.6    Kang, C.7    Jiang, C.8    You, Y.9    Zhang, Y.10    Chen, C.C.11    Song, S.W.12    Jiang, T.13
  • 80
    • 79953309923 scopus 로고    scopus 로고
    • A ten-microRNA expression signature predicts survival in glioblastoma
    • S. Srinivasan, I. R. Patric and K. Somasundaram: A ten-microRNA expression signature predicts survival in glioblastoma. PLoS One 6(3), e17438 (2011) DOI: 10.1371/journal.pone.0017438
    • (2011) PLoS One , vol.6 , Issue.3 , pp. e17438
    • Srinivasan, S.1    Patric, I.R.2    Somasundaram, K.3
  • 81
    • 84892453256 scopus 로고    scopus 로고
    • Identification of intrinsic subtype-specific prognostic microRNAs in primary glioblastoma
    • R. Li, K. Gao, H. Luo, X. Wang, Y. Shi, Q. Dong, W. Luan and Y. You: Identification of intrinsic subtype-specific prognostic microRNAs in primary glioblastoma. J Exp Clin Cancer Res 33, 9 (2014) DOI: 10.1186/1756-9966-33-9
    • (2014) J Exp Clin Cancer Res , vol.33 , pp. 9
    • Li, R.1    Gao, K.2    Luo, H.3    Wang, X.4    Shi, Y.5    Dong, Q.6    Luan, W.7    You, Y.8
  • 82
    • 84887986474 scopus 로고    scopus 로고
    • Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1
    • S. Lian, R. Shi, T. Bai, Y. Liu, W. Miao, H. Wang, X. Liu and Y. Fan: Anti-miRNA-23a oligonucleotide suppresses glioma cells growth by targeting apoptotic protease activating factor-1. Curr Pharm Des 19(35), 6382-9 (2013) DOI: 10.2174/13816128113199990509
    • (2013) Curr Pharm des , vol.19 , Issue.35 , pp. 6382-6389
    • Lian, S.1    Shi, R.2    Bai, T.3    Liu, Y.4    Miao, W.5    Wang, H.6    Liu, X.7    Fan, Y.8
  • 83
    • 84873846295 scopus 로고    scopus 로고
    • MiR-30a-5p antisense oligonucleotide suppresses glioma cell growth by targeting SEPT7
    • Z. Jia, K. Wang, G. Wang, A. Zhang and P. Pu: MiR-30a-5p antisense oligonucleotide suppresses glioma cell growth by targeting SEPT7. PLoS One 8(1), e55008 (2013) DOI: 10.1371/journal.pone.0055008
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e55008
    • Jia, Z.1    Wang, K.2    Wang, G.3    Zhang, A.4    Pu, P.5
  • 84
    • 84865041580 scopus 로고    scopus 로고
    • Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells
    • Doi not found
    • C. G. Dong, W. K. Wu, S. Y. Feng, X. J. Wang, J. F. Shao and J. Qiao: Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells. Int J Oncol 41(3), 1005-12 (2012) Doi not found.
    • (2012) Int J Oncol , vol.41 , Issue.3 , pp. 1005-1012
    • Dong, C.G.1    Wu, W.K.2    Feng, S.Y.3    Wang, X.J.4    Shao, J.F.5    Qiao, J.6
  • 85
    • 84898815056 scopus 로고    scopus 로고
    • MicroRNA in Human Glioma
    • M. Li, J. Li, L. Liu, W. Li, Y. Yang and J. Yuan: MicroRNA in Human Glioma. Cancers (Basel) 5(4), 1306-31 (2013) DOI: 10.3390/cancers5041306
    • (2013) Cancers (Basel) , vol.5 , Issue.4 , pp. 1306-1331
    • Li, M.1    Li, J.2    Liu, L.3    Li, W.4    Yang, Y.5    Yuan, J.6
  • 87
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: Rationale, strategies and challenges
    • R. Garzon, G. Marcucci and C. M. Croce: Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 9(10), 775-89 (2010) DOI: 10.1038/nrd3179
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.10 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 89
    • 83355166283 scopus 로고    scopus 로고
    • Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI
    • Y. P. Yang, Y. Chien, G. Y. Chiou, J. Y. Cherng, M. L. Wang, W. L. Lo, Y. L. Chang, P. I. Huang, Y. W. Chen, Y. H. Shih, M. T. Chen and S. H. Chiou: Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI. Biomaterials 33(5), 1462-76 (2012) DOI: 10.1016/j.biomaterials.2011.10.071
    • (2012) Biomaterials , vol.33 , Issue.5 , pp. 1462-1476
    • Yang, Y.P.1    Chien, Y.2    Chiou, G.Y.3    Cherng, J.Y.4    Wang, M.L.5    Lo, W.L.6    Chang, Y.L.7    Huang, P.I.8    Chen, Y.W.9    Shih, Y.H.10    Chen, M.T.11    Chiou, S.H.12
  • 91
    • 84885351203 scopus 로고    scopus 로고
    • Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM
    • D. W. Dai, Q. Lu, L. X. Wang, W. Y. Zhao, Y. Q. Cao, Y. N. Li, G. S. Han, J. M. Liu and Z. J. Yue: Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM. BMC Cancer 13, 478 (2013) DOI: 10.1186/1471-2407-13-478
    • (2013) BMC Cancer , vol.13 , pp. 478
    • Dai, D.W.1    Lu, Q.2    Wang, L.X.3    Zhao, W.Y.4    Cao, Y.Q.5    Li, Y.N.6    Han, G.S.7    Liu, J.M.8    Yue, Z.J.9
  • 92
    • 84883625637 scopus 로고    scopus 로고
    • Low-expression of microRNA-107 inhibits cell apoptosis in glioma by upregulation of SALL4
    • J. He, W. Zhang, Q. Zhou, T. Zhao, Y. Song, L. Chai and Y. Li: Low-expression of microRNA-107 inhibits cell apoptosis in glioma by upregulation of SALL4. Int J Biochem Cell Biol 45(9), 1962-73 (2013) DOI: 10.1016/j.biocel.2013.06.008
    • (2013) Int J Biochem Cell Biol , vol.45 , Issue.9 , pp. 1962-1973
    • He, J.1    Zhang, W.2    Zhou, Q.3    Zhao, T.4    Song, Y.5    Chai, L.6    Li, Y.7
  • 93
    • 80655149145 scopus 로고    scopus 로고
    • microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling
    • K. M. Lee, E. J. Choi and I. A. Kim: microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling. Radiother Oncol 101(1), 171-6 (2011) DOI: 10.1016/j.radonc.2011.05.050
    • (2011) Radiother Oncol , vol.101 , Issue.1 , pp. 171-176
    • Lee, K.M.1    Choi, E.J.2    Kim, I.A.3
  • 94
    • 77956178738 scopus 로고    scopus 로고
    • MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity
    • L. Shi, J. Chen, J. Yang, T. Pan, S. Zhang and Z. Wang: MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res 1352, 255-64 (2010) DOI: 10.1016/j.brainres.2010.07.009
    • (2010) Brain Res , vol.1352 , pp. 255-264
    • Shi, L.1    Chen, J.2    Yang, J.3    Pan, T.4    Zhang, S.5    Wang, Z.6
  • 95
    • 84867500470 scopus 로고    scopus 로고
    • Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines
    • H. S. Gwak, T. H. Kim, G. H. Jo, Y. J. Kim, H. J. Kwak, J. H. Kim, J. Yin, H. Yoo, S. H. Lee and J. B. Park: Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines. PLoS One 7(10), e47449 (2012) DOI: 10.1371/journal.pone.0047449
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e47449
    • Gwak, H.S.1    Kim, T.H.2    Jo, G.H.3    Kim, Y.J.4    Kwak, H.J.5    Kim, J.H.6    Yin, J.7    Yoo, H.8    Lee, S.H.9    Park, J.B.10
  • 96
    • 78049414216 scopus 로고    scopus 로고
    • Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J
    • W. L. Ng, D. Yan, X. Zhang, Y. Y. Mo and Y. Wang: Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J. DNA Repair (Amst) 9(11), 1170-5 (2010) DOI: 10.1016/j.dnarep.2010.08.007
    • (2010) DNA Repair (Amst) , vol.9 , Issue.11 , pp. 1170-1175
    • Ng, W.L.1    Yan, D.2    Zhang, X.3    Mo, Y.Y.4    Wang, Y.5
  • 97
    • 84455194000 scopus 로고    scopus 로고
    • MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis
    • Doi not found
    • L. Shi, S. Zhang, K. Feng, F. Wu, Y. Wan, Z. Wang, J. Zhang, Y. Wang, W. Yan, Z. Fu and Y. You: MicroRNA-125b-2 confers human glioblastoma stem cells resistance to temozolomide through the mitochondrial pathway of apoptosis. Int J Oncol 40(1), 119-29 (2012) Doi not found.
    • (2012) Int J Oncol , vol.40 , Issue.1 , pp. 119-129
    • Shi, L.1    Zhang, S.2    Feng, K.3    Wu, F.4    Wan, Y.5    Wang, Z.6    Zhang, J.7    Wang, Y.8    Yan, W.9    Fu, Z.10    You, Y.11
  • 98
    • 77949445582 scopus 로고    scopus 로고
    • MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2
    • Doi not found
    • G. Chen, W. Zhu, D. Shi, L. Lv, C. Zhang, P. Liu and W. Hu: MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2. Oncol Rep 23(4), 997-1003 (2010) Doi not found.
    • (2010) Oncol Rep , vol.23 , Issue.4 , pp. 997-1003
    • Chen, G.1    Zhu, W.2    Shi, D.3    Lv, L.4    Zhang, C.5    Liu, P.6    Hu, W.7
  • 100
    • 78049303163 scopus 로고    scopus 로고
    • Downregulation of ABCG2 expression in glioblastoma cancer stem cells with miRNA-328 may decrease their chemoresistance
    • Doi not found
    • W. Q. Li, Y. M. Li, B. B. Tao, Y. C. Lu, G. H. Hu, H. M. Liu, J. He, Y. Xu and H. Y. Yu: Downregulation of ABCG2 expression in glioblastoma cancer stem cells with miRNA-328 may decrease their chemoresistance. Med Sci Monit 16(10), HY27-30 (2010) Doi not found.
    • (2010) Med Sci Monit , vol.16 , Issue.10 , pp. HY27-HY30
    • Li, W.Q.1    Li, Y.M.2    Tao, B.B.3    Lu, Y.C.4    Hu, G.H.5    Liu, H.M.6    He, J.7    Xu, Y.8    Yu, H.Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.