P53-induced microRNA-107 inhibits proliferation of glioma cells and down-regulates the expression of CDK6 and Notch-2

Neuroscience Letters

Volumn 534, Issue 1, 2013, Pages 327-332

  Chen, Lei ^a,b   Zhang, Run ^a,b   Li, Peng ^a,b   Liu, Yi ^a,b   Qin, Kun ^a,b   Fa, Zhi qiang ^a,b   Liu, Yi jing ^a,b   Ke, Yi quan ^a,b   Jiang, Xiao dan ^a,b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

CDK6; Glioma; MiR 107; Notch 2; P53

Indexed keywords

CYCLIN DEPENDENT KINASE 6; MICRORNA 107; NOTCH2 RECEPTOR; PROTEIN P53;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CELL CYCLE G0 PHASE; CONTROLLED STUDY; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GLIOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 6; DOWN-REGULATION; GLIOMA; HUMANS; LENTIVIRUS; MICRORNAS; RECEPTOR, NOTCH2; TRANSDUCTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84873057852     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.11.047     Document Type: Article

References (32)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
2. Boominathan L. The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex. PLoS ONE 2010, 5:e10615.
3. Bryant R.J., Pawlowski T., Catto J.W., Marsden G., Vessella R.L., Rhees B., Kuslich C., Visakorpi T., Hamdy F.C. Changes in circulating microRNA levels associated with prostate cancer. British Journal of Cancer 2012, 106:768-774.
4. Buschges R., Weber R.G., Actor B., Lichter P., Collins V.P., Reifenberger G. Amplification and expression of cyclin D genes (CCND1, CCND2 and CCND3) in human malignant gliomas. Brain Pathology 1999, 9:435-442. (discussion 432-433).
5. Chen J., Kesari S., Rooney C., Strack P.R., Chen J., Shen H., Wu L., Griffin J.D. Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. Genes and Cancer 2010, 1:822-835.
6. Corsten M.F., Miranda R., Kasmieh R., Krichevsky A.M., Weissleder R., Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Research 2007, 67:8994-9000.
7. Cui J.G., Zhao Y., Sethi P., Li Y.Y., Mahta A., Culicchia F., Lukiw W.J. Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation. Journal of Neuro-Oncology 2010, 98:297-304.
8. Datta J., Smith A., Lang J.C., Islam M., Dutt D., Teknos T.N., Pan Q. microRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase Cvarepsilon. Oncogene 2012, 31:4045-4053.
9. Feng L., Xie Y., Zhang H., Wu Y. miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells. Medical Oncology 2012, 29:856-863.
10. Furnari F.B., Fenton T., Bachoo R.M., Mukasa A., Stommel J.M., Stegh A., Hahn W.C., Ligon K.L., Louis D.N., Brennan C., Chin L., DePinho R.A., Cavenee W.K. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes and Development 2007, 21:2683-2710.
11. Gartel A.L., Kandel E.S. miRNAs: little known mediators of oncogenesis. Seminars in Cancer Biology 2008, 18:103-110.
12. Gaur A., Jewell D.A., Liang Y., Ridzon D., Moore J.H., Chen C., Ambros V.R., Israel M.A. Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Research 2007, 67:2456-2468.
13. Hermeking H. p53 enters the microRNA world. Cancer Cell 2007, 12:414-418.
14. Lam P.Y., Di Tomaso E., Ng H.K., Pang J.C., Roussel M.F., Hjelm N.M. Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme. British Journal of Neurosurgery 2000, 14:28-32.
15. Lee K.H., Lotterman C., Karikari C., Omura N., Feldmann G., Habbe N., Goggins M.G., Mendell J.T., Maitra A. Epigenetic silencing of microRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology 2009, 9:293-301.
16. Lee S.T., Chu K., Oh H.J., Im W.S., Lim J.Y., Kim S.K., Park C.K., Jung K.H., Lee S.K., Kim M., Roh J.K. Let-7 microRNA inhibits the proliferation of human glioblastoma cells. Journal of Neuro-Oncology 2011, 102:19-24.
17. Lewis B.P., Burge C.B., Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120:15-20.
18. Li Y., Guessous F., Zhang Y., Dipierro C., Kefas B., Johnson E., Marcinkiewicz L., Jiang J., Yang Y., Schmittgen T.D., Lopes B., Schiff D., Purow B., Abounader R. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Research 2009, 69:7569-7576.
19. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
20. Mason W.P., Cairncross J.G. Drug insight: temozolomide as a treatment for malignant glioma-impact of a recent trial. Nature Clinical Practice Neurology 2005, 1:88-95.
21. Piao L., Zhang M., Datta J., Xie X., Su T., Li H., Teknos T.N., Pan Q. Lipid-based nanoparticle delivery of pre-miR-107 inhibits the tumorigenicity of head and neck squamous cell carcinoma. Molecular Therapy 2012, 20:1261-1269.
22. Sasayama T., Nishihara M., Kondoh T., Hosoda K., Kohmura E. MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC. International Journal of Cancer 2009, 125:1407-1413.
23. Shyu A.B., Wilkinson M.F., van Hoof A. Messenger RNA regulation: to translate or to degrade. EMBO Journal 2008, 27:471-481.
24. Sivasankaran B., Degen M., Ghaffari A., Hegi M.E., Hamou M.F., Ionescu M.C., Zweifel C., Tolnay M., Wasner M., Mergenthaler S., Miserez A.R., Kiss R., Lino M.M., Merlo A., Chiquet-Ehrismann R., Boulay J.L. Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas. Cancer Research 2009, 69:458-465.
25. Stupp R., Mason W.P., van den Bent M.J., Weller M., Fisher B., Taphoorn M.J., Belanger K., Brandes A.A., Marosi C., Bogdahn U., Curschmann J., Janzer R.C., Ludwin S.K., Gorlia T., Allgeier A., Lacombe D., Cairncross J.G., Eisenhauer E., Mirimanoff R.O. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. New England Journal of Medicine 2005, 352:987-996.
26. Suzuki H.I., Yamagata K., Sugimoto K., Iwamoto T., Kato S., Miyazono K. Modulation of microRNA processing by p53. Nature 2009, 460:529-533.
27. Takahashi Y., Forrest A.R., Maeno E., Hashimoto T., Daub C.O., Yasuda J. MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines. PLoS ONE 2009, 4:e6677.
28. Wen P.Y., Kesari S. Malignant gliomas in adults. New England Journal of Medicine 2008, 359:492-507.
29. Wiedemeyer W.R., Dunn I.F., Quayle S.N., Zhang J., Chheda M.G., Dunn G.P., Zhuang L., Rosenbluh J., Chen S., Xiao Y., Shapiro G.I., Hahn W.C., Chin L. Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:11501-11506.
30. Yamakuchi M., Lotterman C.D., Bao C., Hruban R.H., Karim B., Mendell J.T., Huso D., Lowenstein C.J. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:6334-6339.
31. Zamore P.D., Haley B. Ribo-gnome: the big world of small RNAs. Science 2005, 309:1519-1524.
32. Zhang B., Pan X., Cobb G.P., Anderson T.A. microRNAs as oncogenes and tumor suppressors. Developmental Biology 2007, 302:1-12.