-
1
-
-
0037416187
-
TACE is required for the activation of the EGFR by TGF-alpha in tumors
-
Borrell-Pages M, Rojo F, Albanell J, Baselga J, Arribas J. TACE is required for the activation of the EGFR by TGF-alpha in tumors. EMBO J 2003; 22: 1114-1124.
-
(2003)
EMBO J
, vol.22
, pp. 1114-1124
-
-
Borrell-Pages, M.1
Rojo, F.2
Albanell, J.3
Baselga, J.4
Arribas, J.5
-
2
-
-
0036133646
-
Tumor necrosis factor-alpha converting enzyme
-
Black RA. Tumor necrosis factor-alpha converting enzyme. Int J Biochem Cell Biol 2002; 34: 1-5.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1-5
-
-
Black, R.A.1
-
3
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
-
Black RA, Rauch CT, Kozlosky CJ, et al. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 1997; 385: 729-733.
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
-
4
-
-
14444272986
-
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor
-
Buxbaum JD, Liu KN, Luo Y, et al. Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor. J Biol Chem 1998; 273: 27765-27767.
-
(1998)
J Biol Chem
, vol.273
, pp. 27765-27767
-
-
Buxbaum, J.D.1
Liu, K.N.2
Luo, Y.3
-
5
-
-
27944500753
-
Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17
-
Zatovicova M, Sedlakova O, Svastova E, et al. Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17. Br J Cancer 2005; 93: 1267-1276.
-
(2005)
Br J Cancer
, vol.93
, pp. 1267-1276
-
-
Zatovicova, M.1
Sedlakova, O.2
Svastova, E.3
-
6
-
-
0028919856
-
A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes
-
Crowe PD, Walter BN, Mohler KM, Otten-Evans C, Black RA, Ware CF. A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes. J Exp Med 1995; 181: 1205-1210.
-
(1995)
J Exp Med
, vol.181
, pp. 1205-1210
-
-
Crowe, P.D.1
Walter, B.N.2
Mohler, K.M.3
Otten-Evans, C.4
Black, R.A.5
Ware, C.F.6
-
7
-
-
0028799113
-
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
-
Mullberg J, Durie FH, Otten-Evans C, et al. A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor. J Immunol 1995; 155: 5198-5205.
-
(1995)
J Immunol
, vol.155
, pp. 5198-5205
-
-
Mullberg, J.1
Durie, F.H.2
Otten-Evans, C.3
-
8
-
-
8044250278
-
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha
-
Moss ML, Jin SL, Milla ME, et al. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 1997; 385: 733-736.
-
(1997)
Nature
, vol.385
, pp. 733-736
-
-
Moss, M.L.1
Jin, S.L.2
Milla, M.E.3
-
9
-
-
0029975125
-
Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: Functional consequences for neutrophil aggregation
-
Bennett TA, Lynam EB, Sklar LA, Rogelj S. Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: Functional consequences for neutrophil aggregation. J Immunol 1996; 156: 3093-3097.
-
(1996)
J Immunol
, vol.156
, pp. 3093-3097
-
-
Bennett, T.A.1
Lynam, E.B.2
Sklar, L.A.3
Rogelj, S.4
-
10
-
-
70149102895
-
Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17
-
Katakowski M, Jiang F, Zheng X, Gutierrez JA, Szalad A, Chopp M. Tumorigenicity of cortical astrocyte cell line induced by the protease ADAM17. Cancer Sci 2009; 100: 1597-1604.
-
(2009)
Cancer Sci
, vol.100
, pp. 1597-1604
-
-
Katakowski, M.1
Jiang, F.2
Zheng, X.3
Gutierrez, J.A.4
Szalad, A.5
Chopp, M.6
-
11
-
-
56749133149
-
The ADAMs: Signalling scissors in the tumour microenvironment
-
Murphy G. The ADAMs: Signalling scissors in the tumour microenvironment. Nat Rev Cancer 2008; 8: 932-941.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 932-941
-
-
Murphy, G.1
-
12
-
-
34147169062
-
Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness
-
Zheng X, Jiang F, Katakowski M, et al. Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness. Cancer Sci 2007; 98: 674-684.
-
(2007)
Cancer Sci
, vol.98
, pp. 674-684
-
-
Zheng, X.1
Jiang, F.2
Katakowski, M.3
-
13
-
-
67649095267
-
ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation
-
Zheng X, Jiang F, Katakowski M, Zhang ZG, Lu QE, Chopp M. ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation. Cancer Biol Ther 2009; 8: 1045-1054.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1045-1054
-
-
Zheng, X.1
Jiang, F.2
Katakowski, M.3
Zhang, Z.G.4
Lu, Q.E.5
Chopp, M.6
-
14
-
-
11244261160
-
ADAMs: Key components in EGFR signalling and development
-
Blobel CP. ADAMs: Key components in EGFR signalling and development. Nat Rev Mol Cell Biol 2005; 6: 32-43.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 32-43
-
-
Blobel, C.P.1
-
15
-
-
33947532343
-
Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity
-
Katakowski M, Chen J, Zhang ZG, Santra M, Wang Y, Chopp M. Stroke-induced subventricular zone proliferation is promoted by tumor necrosis factor-alpha-converting enzyme protease activity. J Cereb Blood Flow Metab 2007; 27: 669-678.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 669-678
-
-
Katakowski, M.1
Chen, J.2
Zhang, Z.G.3
Santra, M.4
Wang, Y.5
Chopp, M.6
-
16
-
-
0036883358
-
Glioblastomas: Clinical study and search for prognostic factors
-
Mineo JF, Quintin-Roue I, Lucas B, Buburusan V, Besson G. Glioblastomas: Clinical study and search for prognostic factors. Neurochirurgie 2002; 48: 500-509.
-
(2002)
Neurochirurgie
, vol.48
, pp. 500-509
-
-
Mineo, J.F.1
Quintin-Roue, I.2
Lucas, B.3
Buburusan, V.4
Besson, G.5
-
17
-
-
0038806501
-
TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase
-
Lee DC, Sunnarborg SW, Hinkle CL, et al. TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase. Ann NY Acad Sci 2003; 995: 22-38.
-
(2003)
Ann NY Acad Sci
, vol.995
, pp. 22-38
-
-
Lee, D.C.1
Sunnarborg, S.W.2
Hinkle, C.L.3
-
18
-
-
0033573049
-
Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
-
Fan H, Derynck R. Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J 1999; 18: 6962-6972.
-
(1999)
EMBO J
, vol.18
, pp. 6962-6972
-
-
Fan, H.1
Derynck, R.2
-
20
-
-
0037096945
-
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion
-
Lal A, Glazer CA, Martinson HM, et al. Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion. Cancer Res 2002; 62: 3335-3339.
-
(2002)
Cancer Res
, vol.62
, pp. 3335-3339
-
-
Lal, A.1
Glazer, C.A.2
Martinson, H.M.3
-
21
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta SR, Brunet A, Greenberg ME. Cellular survival: A play in three Akts. Genes Dev 1999; 13: 2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
22
-
-
0034987702
-
Malignant glioma: Genetics and biology of a grave matter
-
Maher EA, Furnari FB, Bachoo RM, et al. Malignant glioma: Genetics and biology of a grave matter. Genes Dev 2001; 15: 1311-1333.
-
(2001)
Genes Dev
, vol.15
, pp. 1311-1333
-
-
Maher, E.A.1
Furnari, F.B.2
Bachoo, R.M.3
-
23
-
-
0034927062
-
The developmental biology of brain tumors
-
Wechsler-Reya R, Scott MP. The developmental biology of brain tumors. Annu Rev Neurosci 2001; 24: 385-428.
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 385-428
-
-
Wechsler-Reya, R.1
Scott, M.P.2
-
24
-
-
0029398189
-
Gene amplification in human gliomas
-
Collins VP. Gene amplification in human gliomas. Glia 1995; 15: 289-296.
-
(1995)
Glia
, vol.15
, pp. 289-296
-
-
Collins, V.P.1
-
25
-
-
0029146954
-
EGFR gene amplification-Rearrangement in human glioblastomas
-
Schwechheimer K, Huang S, Cavenee WK. EGFR gene amplification-Rearrangement in human glioblastomas. Int J Cancer 1995; 62: 145-148.
-
(1995)
Int J Cancer
, vol.62
, pp. 145-148
-
-
Schwechheimer, K.1
Huang, S.2
Cavenee, W.K.3
-
27
-
-
8544273759
-
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling
-
Skinner HD, Zheng JZ, Fang J, Agani F, Jiang BH. Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling. J Biol Chem 2004; 279: 45643-45651.
-
(2004)
J Biol Chem
, vol.279
, pp. 45643-45651
-
-
Skinner, H.D.1
Zheng, J.Z.2
Fang, J.3
Agani, F.4
Jiang, B.H.5
-
28
-
-
0034141195
-
The ADAM gene family: Surface proteins with adhesion and protease activity
-
Primakoff P, Myles DG. The ADAM gene family: Surface proteins with adhesion and protease activity. Trends Genet 2000; 16: 83-87.
-
(2000)
Trends Genet
, vol.16
, pp. 83-87
-
-
Primakoff, P.1
Myles, D.G.2
-
29
-
-
45549084638
-
UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes
-
He YY, Council SE, Feng L, Chignell CF. UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes. Cancer Res 2008; 68: 3752-3758.
-
(2008)
Cancer Res
, vol.68
, pp. 3752-3758
-
-
He, Y.Y.1
Council, S.E.2
Feng, L.3
Chignell, C.F.4
-
30
-
-
43949092082
-
Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion
-
Zheng X, Jiang F, Katakowski M, et al. Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion. Cancer Lett 2008; 265: 177-187.
-
(2008)
Cancer Lett
, vol.265
, pp. 177-187
-
-
Zheng, X.1
Jiang, F.2
Katakowski, M.3
-
31
-
-
4544221034
-
ADAM17 mRNA expression and pathological features of hepatocellular carcinoma
-
Ding X, Yang LY, Huang GW, Wang W, Lu WQ. ADAM17 mRNA expression and pathological features of hepatocellular carcinoma. World J Gastroenterol 2004; 10: 2735-2739.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 2735-2739
-
-
Ding, X.1
Yang, L.Y.2
Huang, G.W.3
Wang, W.4
Lu, W.Q.5
-
32
-
-
38149015503
-
PI3K/PTEN signaling in tumorigenesis and angiogenesis
-
Jiang BH, Liu LZ. PI3K/PTEN signaling in tumorigenesis and angiogenesis. Biochim Biophys Acta 2008; 1784: 150-158.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 150-158
-
-
Jiang, B.H.1
Liu, L.Z.2
-
33
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu Rev Med 2006; 57: 1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
34
-
-
33748284463
-
Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression
-
Xia C, Meng Q, Cao Z, Shi X, Jiang BH. Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression. J Cell Physiol 2006; 209: 56-66.
-
(2006)
J Cell Physiol
, vol.209
, pp. 56-66
-
-
Xia, C.1
Meng, Q.2
Cao, Z.3
Shi, X.4
Jiang, B.H.5
-
35
-
-
0034652392
-
Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells
-
Jiang BH, Zheng JZ, Aoki M, Vogt PK. Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. Proc Natl Acad Sci USA 2000; 97: 1749-1753.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1749-1753
-
-
Jiang, B.H.1
Zheng, J.Z.2
Aoki, M.3
Vogt, P.K.4
-
36
-
-
0033588816
-
A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group
-
Shand N, Weber F, Mariani L, et al. A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum Gene Ther 1999; 10: 2325-2335.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2325-2335
-
-
Shand, N.1
Weber, F.2
Mariani, L.3
-
37
-
-
1542510624
-
Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor
-
Hart S, Fischer OM, Ullrich A. Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor. Cancer Res 2004; 64: 1943-1950.
-
(2004)
Cancer Res
, vol.64
, pp. 1943-1950
-
-
Hart, S.1
Fischer, O.M.2
Ullrich, A.3
-
38
-
-
33744813041
-
EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing
-
Ruhe JE, Streit S, Hart S, Ullrich A. EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing. Cell Signal 2006; 18: 1515-1527.
-
(2006)
Cell Signal
, vol.18
, pp. 1515-1527
-
-
Ruhe, J.E.1
Streit, S.2
Hart, S.3
Ullrich, A.4
-
39
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984; 309: 418-425.
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
-
40
-
-
34548189041
-
Three-dimensional extracellular matrix culture models of EGFR signalling and drug response
-
Kenny PA. Three-dimensional extracellular matrix culture models of EGFR signalling and drug response. Biochem Soc Trans 2007; 35: 665-668.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 665-668
-
-
Kenny, P.A.1
-
41
-
-
36048938454
-
TACE: A new target in epidermal growth factor receptor dependent tumors
-
Kenny PA. TACE: A new target in epidermal growth factor receptor dependent tumors. Differentiation 2007; 75: 800-808.
-
(2007)
Differentiation
, vol.75
, pp. 800-808
-
-
Kenny, P.A.1
-
42
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000; 19: 6550-6565.
-
(2000)
Oncogene
, vol.19
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
43
-
-
1442358746
-
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
-
Sahin U, Weskamp G, Kelly K, et al. Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J Cell Biol 2004; 164: 769-779.
-
(2004)
J Cell Biol
, vol.164
, pp. 769-779
-
-
Sahin, U.1
Weskamp, G.2
Kelly, K.3
|