Fatty acids, lipid emulsions and the immune and inflammatory systems

World Review of Nutrition and Dietetics

Volumn 112, Issue , 2015, Pages 17-30

  Miles, Elizabeth A ^a   Calder, Philip C ^a,b,c  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^c KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE MAX;

EMULSION; FAT INTAKE; FATTY ACID; FISH OIL; OLIVE OIL; OMEGA 6 FATTY ACID; SOYBEAN OIL;

ABDOMINAL SURGERY; ADMINISTRATION AND DOSAGE; CHEMISTRY; CRITICAL ILLNESS; DRUG EFFECTS; EMULSION; FAT INTAKE; HUMAN; IMMUNE SYSTEM; INFLAMMATION; PARENTERAL NUTRITION; POSTOPERATIVE COMPLICATIONS; PROCEDURES;

CRITICAL ILLNESS; DIETARY FATS; DIGESTIVE SYSTEM SURGICAL PROCEDURES; EMULSIONS; FATTY ACIDS; FATTY ACIDS, OMEGA-6; FISH OILS; HUMANS; IMMUNE SYSTEM; INFLAMMATION; OLIVE OIL; PARENTERAL NUTRITION; POSTOPERATIVE COMPLICATIONS; SOYBEAN OIL;

EID: 84918795210     PISSN: 00842230     EISSN: 16623975     Source Type: Book Series    
DOI: 10.1159/000365426     Document Type: Article

References (48)

1. Calder PC: The 2008 ESPEN Sir David Cuthbertson Lecture: fatty acids and inflammation - from the membrane to the nucleus and from the laboratory bench to the clinic. Clin Nutr 2010;29:5-12.
2. Kim W, Khan NA, McMurray DN, Prior IA, Wang N, Chapkin RS: Regulatory activity of polyunsaturated fatty acids in T-cell signaling. Prog Lipid Res 2010;49:250-261.
3. Calder PC: Fatty acids and inflammation: the cutting edge between food and pharma. Eur J Pharmacol 2011;668(suppl 1):S50-S58.
4. Calder PC: Long-chain fatty acids and inflammation. Proc Nutr Soc 2012;71:284-289.
5. Shaikh SR, Jolly CA, Chapkin RS: n-3 Polyunsaturated fatty acids exert immunomodulatory effects on lymphocytes by targeting plasma membrane molecular organization. Mol Aspects Med 2012;33:46-54.
6. Calder PC: n-3 fatty acids, inflammation and immunity: new mechanisms to explain old actions. Proc Nutr Soc 2013;72:326-336.
7. Calder PC: Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? Br J Clin Pharmacol 2013;75:645-662.
8. Calder PC: Use of fish oil in parenteral nutrition: rationale and reality. Proc Nutr Soc 2006;65:264-277.
9. Calder PC: Immunonutrition in surgical and critically ill patients. Br J Nutr 2007;98:S133-S139.
10. Calder PC: Rationale for using new lipid emulsions in parenteral nutrition and a review of the trials performed in adults. Proc Nutr Soc 2009;68:252-260.
11. Calder PC: Rationale and use of n-3 fatty acids in artificial nutrition. Proc Nutr Soc 2010;69:565-573.
12. Calder PC: Lipids for intravenous nutrition in hospitalised adult patients: a multiple choice of options. Proc Nutr Soc 2013;72:263-276.
13. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992;101:1644-1655.
14. Ward NS, Casserly B, Ayala A: The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients. Clin Chest Med 2008;29:617-625.
15. Wanten G: An update on parenteral lipids and immune function: only smoke, or is there any fire? Curr Opin Clin Nutr Metab Care 2006;9:79-83.
16. Calder PC, Yaqoob P, Newsholme EA: Triacylglycerol metabolism by lymphocytes and the effect of triacylglycerols on lymphocyte proliferation. Biochem J 1994;298:605-611.
17. Calder PC, Yaqoob P, Harvey DJ, Watts A, Newsholme EA: The incorporation of fatty acids by lymphocytes and the effect on fatty acid composition and membrane fluidity. Biochem J 1994;300:509-518.
18. Lewis RA, Austen KF, Soberman RJ: Leukotrienes and other products of the 5-lipoxygenase pathway: biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990;323:645-655.
19. Tilley SL, Coffman TM, Koller BH: Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. J Clin Invest 2001;108:15-23.
20. Heyland DK, MacDonald S, Keefe L, Drover JW: Total parenteral nutrition in the critically ill patient: a meta analysis. JAMA 1998;280:2013-2019.
21. Koch T, Heller AR: Auswirkungen einer parenteralen Ernährung mit n-3-Fettsäuren auf das Therapieergebnis - Eine multizentrische Analyse bei 661 Patienten. Aktuellle Ernährungsmedizin 2005;30:15-22.
22. Dionigi P, Dionigi R, Prati U, Pavesi F, Jemos V, Nazari S: Effect of Intralipid ® on some immunological parameters and leukocyte functions in patients with esophageal and gastric cancer. Clin Nutr 1985;4:229-234.
23. Monson JRT, Sedman PC, Ramsden CW, Brennan TG, Guillou PJ: Total parenteral nutrition adversely influences tumour-directed cellular cytotoxic responses in patients with gastrointestinal cancer. Eur J Surg Oncol 1988;14:435-443.
24. Gogos CA, Kalfarentzos FE, Zoumbos NC: Effect of different types of total parenteral nutrition on T-lymphocyte subpopulations and NK cells. Am J Clin Nutr 1990;51:119-122.
25. Sedman PC, Somers SS, Ramsden CW, Brennan TG, Guillou PJ: Effects of different lipid emulsions on lymphocyte function during total parenteral nutrition. Br J Surg 1991;78:1396-1399.
26. Battistella FD, Widergren JT, Anderson JT, Siepler JK, Weber JC, MacColl K: A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition. J Trauma 1997;43:52-58.
27. Lenssen P, Bruemmer BA, Bowden RA, Gooley T, Aker SN, Mattson D: Intravenous lipid dose and incidence of bacteremia and fungemia in patients undergoing bone marrow transplantation. Am J Clin Nutr 1998;67:927-933.
28. Furukawa K, Yamamori H, Takagi K, Hayashi N, Suzuki R, Nakajima N, Tashiro T: Influences of soybean oil emulsion on stress response and cell mediated immune function in moderately or severely stressed patients. Nutrition 2002;18:235-240.
29. Granato D, Blum S, Rossle C, Le Boucher J, Malnoë A, Dutot G: Effects of parenteral lipid emulsions with different fatty acid composition on immune cell functions in vitro. JPEN J Parenter Enteral Nutr 2000;24:113-118.
30. Reimund JM, Rahmi G, Escalin G, Pinna G, Finck G, Muller CD, Duclos B, Baumann R: Efficacy and safety of an olive oil-based intravenous fat emulsion in adult patients on home parenteral nutrition. Aliment Pharmacol Ther 2005;21:445-454.
31. Cano NJ, Saingra Y, Dupuy AM, Lorec-Penet AM, Portugal H, Lairon D, Cristol JP, Come A, Le Brun A, Atlan P, Leverve XM: Intradialytic parenteral nutrition: comparison of olive oil versus soybean oilbased lipid emulsions. Br J Nutr 2006;95:152-159.
32. Mateu-De Antonio J, Grau S, Luque S, Marín-Casino M, Albert I, Ribes E: Comparative effects of olive oilbased and soyabean oil-based emulsions on infection rate and leucocyte count in critically ill patients receiving parenteral nutrition. Br J Nutr 2008;99:846-854.
33. Garcia-De-Lorenzo A, Denia R, Atlan P, Martinez-Ratero S, Le Brun A, Evard D, Bereziat G: Parenteral nutrition providing a restricted amount of linoleic acid in severely burned patients: a randomised double-blind study of an olive oil-based lipid emulsion v. medium/long chain triacylglycerols. Br J Nutr 2005;94:221-230.
34. Umpierrez GE, Spiegelman R, Zhao V, Smiley DD, Pinzon I, Griffith DP, Peng L, Morris T, Luo M, Garcia H, Thomas C, Newton CA, Ziegler TR: A doubleblind, randomized clinical trial comparing soybean oil-based versus olive oil-based lipid emulsions in adult medical-surgical intensive care unit patients requiring parenteral nutrition. Crit Care Med 2012;40:1792-1798.
35. Serhan CN, Chiang N, Van Dyke TE: Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 2008;8:349-361.
36. Morlion BJ, Torwesten E, Lessire A, Sturm G, Peskar BM, Fürst P, Puchstein C: The effect of parenteral fish oil on leukocyte membrane fatty acid composition and leukotriene-synthesizing capacity in postoperative trauma. Metabolism 1996;45:1208-1213.
37. Wachtler P, Konig W, Senkal M, Kemen M, Köller M: Influence of a total parenteral nutrition enriched with w-3 fatty acids on leukotriene synthesis of peripheral leukocytes and systemic cytokine levels in patients with major surgery. J Trauma 1997;42:191-198.
38. Koller M, Senkal M, Kemen M, König W, Zumtobel V, Muhr G: Impact of omega-3 fatty acid enriched TPN on leukotriene synthesis by leukocytes after major surgery. Clin Nutr 2003;22:59-64.
39. Grimm H, Mertes N, Goeters C, Schlotzer E, Mayer K, Grimminger F, Fürst P: Improved fatty acid and leukotriene pattern with a novel lipid emulsion in surgical patients. Eur J Nutr 2006;45:55-60.
40. Weiss G, Meyer F, Matthies B, Pross M, Koenig W, Lippert H: Immunomodulation by perioperative administration of n-3 fatty acids. Br J Nutr 2002;87:S89-S94.
41. Schauder P, Rohn U, Schafer G, Korff G, Schenk HD: Impact of fish oil enriched total parenteral nutrition on DNA synthesis, cytokine release and receptor expression by lymphocytes in the postoperative period. Br J Nutr 2002;87:S103-S110.
42. Mayer K, Fegbeutel C, Hattar K, Sibelius U, Krämer HJ, Heuer KU, Temmesfeld-Wollbrück B, Gokorsch S, Grimminger F, Seeger W: Omega-3 vs omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation. Intens Care Med 2003;29:1472-1481.
43. Mayer K, Gokorsch S, Fegbeutel C, Hattar K, Rosseau S, Walmrath D, Seeger W, Grimminger F: Parenteral nutrition with fish oil modulates cytokine response in patients with sepsis. Am J Respir Crit Care Med 2003;167:1321-1328.
44. Wang X, Li W, Li N, Li J: Omega-3 fatty acids-supplemented parenteral nutrition decreases hyperinflammatory response and attenuates systemic disease sequelae in severe acute pancreatitis: a randomized and controlled study. JPEN J Parenter Enteral Nutr 2008;32:236-241.
45. Barbosa VM, Miles EA, Calhau C, Lafuente E, Calder PC: Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Crit Care 2010;14:R5.
46. Friesecke S, Lotze C, Kohler J, Heinrich A, Felix SB, Abel P: Fish oil supplementation in the parenteral nutrition of critically ill medical patients: a randomised controlled trial. Intens Care Med 2008;34:1411-1420.
47. Calder PC: Fishing for improved outcomes in the critically ill. Crit Care Med 2014;42:1306-1307.
48. Heller AR, Rossler S, Litz RJ, Stehr SN, Heller SC, Koch R, Koch T: Omega-3 fatty acids improve the diagnosis-related clinical outcome. Crit Care Med 2006;4:972-979.