Influence of a total parenteral nutrition enriched with ω-3 fatty acids on leukotriene synthesis of peripheral leukocytes and systemic cytokine levels in patients with major surgery

Journal of Trauma - Injury, Infection and Critical Care

Volumn 42, Issue 2, 1997, Pages 191-198

  Wachtler, P ^a   Konig W ^a   Senkal, M ^b   Kernen, M ^b   Koller M ^a,b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b ST JOSEF HOSPITAL   (Germany)

Author keywords

Cytokines; Eicosapentaenoic acid; Leukotrienes; Omega 3 fatty acids; Postoperative infection; Total parenteral nutrition

Indexed keywords

ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FAT INTAKE; FEMALE; HUMAN; IMMUNOMODULATION; LEUKOCYTE; LEUKOCYTE FUNCTION; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURGICAL PATIENT; TOTAL PARENTERAL NUTRITION;

EID: 0343923728     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/00005373-199702000-00004     Document Type: Article

References (40)

1. Baue AE: Nutrition and metabolism in sepsis and multisystem organ failure. Surg Clin North Am 71:549, 1991
2. Abraham E: Physiologic stress and cellular ischemia: Relationship to immuno-suppression and susceptibility to sepsis. Crit Care Med 19:613, 1991
3. Utoh J, Yamamoto T, Utsunomiya T, et al: Effect of surgery on neutrophil functions, superoxide and leukotriene production. Br J Surg 75:682, 1988
4. Curtis GE, McAtear CA, Formela L, et al: The effect of nutritional status on the cytokine and acute phase protein responses to elective surgery. Cytokine 7:380, 1995
5. Borgeat P, Samuelsson B: Arachidonic acid metabolism in polymorphonuclear leukocytes: Effects of ionophore 23187. Proc Natl Acad Sci USA 76:2148, 1979
6. König W, Schönfeld W, Raulf M, et al: The neutrophil and leukotrienes: Role in health and disease. Eicosanoids 3:1, 1990
7. 5 in complement receptor enhancement, lysozyme release and chemotaxis of human neutrophils. Clin Sci 74:467, 1988
8. 4 in human polymorphonuclear leukocytes. Biochem Biophys Res Commun 133:23, 1985
9. Sirois P, Brousseau Y, Salari H, et al: Correlation between the myotropic activity of leukotriene A4 on guinea-pig lung, trachea and ileum and its biotransformation in situ. Prostaglandins 30:21, 1985
10. 4 enhances interleukin-6 (IL-6) production and IL-6 messenger RNA accumulation in human monocytes in vitro: Transcriptional and posttranscriptional mechanisms. Blood 80:1004, 1992
11. Bates EJ, Ferrante A, Harvey DP, et al: Polyunsaturated fatty acids increase neutrophil adherence and integrin receptor expression. J Leukocyte Biol 53:420, 1993
12. κ B and NF -IL6. Eur J Immunol 22:2705, 1992
13. Vassali P: The pathophysiology of tumor necrosis factors. Annu Rev Immunol 10:411, 1992
14. Tang GJ, Kuo CD, Yen TC, et al: Perioperative plasma concentrations of tumor necrosis factor-alpha and interleukin-6 in infected patients. Crit Care Med 24:423, 1996
15. Dinarello CA: Interleukin-1 and the pathogenesis of the acute phase response. N Engl J Med 311:1413, 1984
16. Mizel SB: Interleukin 1 and T-cell activation. Immunol Rev 63:51, 1982
17. Tilg H, Atkins MB, Dinarello CA, et al.: Induction of interleukin-10 by interleukin-1 and interleukin-2 but not interleukin-6 immunotherapy. Cytokine 7:734, 1995
18. Nishimoto N, Yoshizaki K, Tagoh H, et al: Evaluation of serum interleukin-6 prior to acute phase proteins on the inflammation by surgical operation. Clin Immunol Immunopathol 50:399, 1989
19. Okzatott H, Yoshizaki K, Nishimoto N, et al: Interleukin-6 as a new indicator of inflammatory status: Detection of serum level of interleukin-6 and c-reactive protein after surgery. Surgery 111:201, 1992
20. Mosmann TR, Moore KW: Role of IL-10 in cross-regulation of Th1 and Th2 responses. Immunol Today 12:A49, 1991
21. De Waal Malefyt R, Yssel H, Roncarolo MG, et al.: Interleukin-10. Curr Opin Immunol 4:312, 1992
22. Sherry RM, Cue JI, Goddard JK, et al: Interleukin-10 is associated with the development of sepsis in trauma patients. J Trauma 40:613, 1996
23. van der Poll T, Coyle SM, Barbosa K, et al: Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. J Clin Invest 97:713, 1996
24. Daly JM, Lieberman MD, Goldfine J, et al: Enteral nutrition with supplemental arginine, RNA, and omega-3 fatty acids in patients after operation: Immunologic, metabolic, and clinical outcome. Surgery 112:56, 1992
25. Moore FA, Moore EE, Kudsk KA, et al: Clinical benefits of an immune-enhancing diet for early postinjury enteral feeding. J Trauma 37:607, 1994
26. Bower RH, Cerra FB, Bershadsky B, et al: Early enteral administration of a formula (Impact®) supplemented with arginine, nucleotides, and fish oil in intensive care unit patients: Results of a multicenter, prospective, randomized, clinical trial. Crit Care Med 23:436, 1995
27. Köller M, König W, Brom J, et al: Generation of leukotrienes from human polymorphonuclear granulocytes of severely burned patients. J Trauma 28:733, 1988
28. Fisher CJ, Opal SM, Dhainaut JF, et al: Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. Crit Care Med 21:318, 1993
29. Clevenger FW: Nutritional support in the patient with the systemic inflammatory response syndrome. Am J Surg 165:68s, 1993
30. Kemen M, Senkal M, Homann HH, et al: Early postoperative enterai nutrition with arginine-omega-3 fatty acids and ribonucleic acid-supplemented diet versus placebo in cancer patients: An immunologic evaluation of Impact. Crit Care Med 23:652, 1995
31. Wachtler P, Hilger RA, König W, et al: Influence of a preoperative enterai supplement on functional activities of peripheral leukocytes from patients with major surgery. Clin Nutr 14:275, 1995
32. Johnson JA, Griswold JA, Muakkassa FF: Essential fatty acids influence survival in sepsis. J Trauma 35:128, 1993
33. Sprecher H: (N-3), and (N-6) fatty acid metabolism. In Galli C, Simopoulos AP (eds): Dietary ω-3 and ω-6 Fatty Acids: Biological Effects and Nutritional Essentiality. NATO ASI Series A: Life Sciences, vol 171. Plenum Press, New York, pp 69-79, 1989
34. Marcus AJ, Hajjar DP: Vascular transcellular signalling. J Lipid Res 34:2017, 1993
35. Rola-Pleszczynski M: Leukotrienes and the immune system. J Lipid Mediators 1:149, 1989
36. Horiguchi J, Spriggs D, Imamura K, et al: Role of arachidonic acid metabolism in transcriptional induction of tumor necrosis factor gene expression by phorbol ester. Mol Cell Biol 9:252, 1989
37. 4 synthesis by a lipoxygenase inhibitor. J Leukocyte Biol 54:269, 1993
38. Endres S, Charbani R, Kelley VE, et al: The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin 1 and tumor necrosis factor by mononuclear cells. N Engl J Med 320:265, 1989
39. 5 by calcium ionophore-activated human eosinophils in vitro. J Immunol 150:3546, 1993
40. Kudsk KA: Clinical applications of enterai nutrition. Nutr Clin Pract 9:165, 1994