Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: First evidence of DNA methylation in Caenorhabditis elegans

Biochemical Journal

Volumn 465, Issue , 2015, Pages 39-47

  Hu, Chiung Wen ^a,b   Chen, Jian Lian ^c   Hsu, Yu Wen ^a   Yen, Cheng Chieh ^a   Chao, Mu Rong ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

5 hydroxymethyl 2 deoxycytidine; 5 methyl 2 deoxycytidine; Cadmium; Caenorhabditis elegans; Decitabine; Liquid chromatography tandem mass spectrometry

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; 5 HYDROXYMETHYLDEOXYURIDINE; 5 METHYLDEOXYCYTIDINE; CADMIUM; CYTOSINE; DNA METHYLTRANSFERASE; GENOMIC DNA; 5-HYDROXYMETHYLCYTOSINE; 5-METHYLDEOXYCYTIDINE; AZACITIDINE; DEOXYCYTIDINE; DNA;

ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; DNA EXTRACTION; DNA ISOLATION; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; GENETIC CONSERVATION; HYDROLYSIS; ISOTOPE DILUTION ASSAY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; NONHUMAN; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; ISOTOPE LABELING; METABOLISM; ONLINE SYSTEM; PROCEDURES; REPRODUCIBILITY;

CAENORHABDITIS ELEGANS; NEMATODA;

ANIMALS; AZACITIDINE; CADMIUM; CAENORHABDITIS ELEGANS; CHROMATOGRAPHY, LIQUID; CYTOSINE; DEOXYCYTIDINE; DNA; DNA METHYLATION; ISOTOPE LABELING; ONLINE SYSTEMS; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 84918547986     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140844     Document Type: Article

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