Prevention of artifactual oxidation in determination of cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction

Free Radical Biology and Medicine

Volumn 44, Issue 3, 2008, Pages 464-473

  Chao, Mu Rong ^a   Yen, Cheng Chieh ^a   Hu, Chiung Wen ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Antioxidant; Artifactual oxidation; Free radicals; LC MS MS; Online SPE; Oxidatively damaged DNA

Indexed keywords

2,2,6,6 TETRAMETHYLPIPERIDIN 1 OXYL; 8 HYDROXYDEOXYGUANOSINE; DEFEROXAMINE; DEOXYGUANOSINE; ISOTOPE; PIPERIDINE DERIVATIVE; PROTEIN HYDROLYSATE; UNCLASSIFIED DRUG;

ARTICLE; AUTOMATION; DNA PURIFICATION; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ONLINE ANALYSIS; OXIDATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SOLID PHASE EXTRACTION; STATISTICAL SIGNIFICANCE;

ANIMALS; ARTIFACTS; CHROMATOGRAPHY, LIQUID; CYCLIC N-OXIDES; DEFEROXAMINE; DEOXYGUANOSINE; DNA; HYDROLYSIS; MASS SPECTROMETRY; MICE; ONLINE SYSTEMS; OXIDATION-REDUCTION; RADIOISOTOPE DILUTION TECHNIQUE; SOLID PHASE EXTRACTION;

EID: 38149019198     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.10.003     Document Type: Article

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