Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria

Free Radical Biology and Medicine

Volumn 77, Issue , 2014, Pages 317-330

  Tretter, L ^a   Horvath, G ^a   Holgyesi A ^a   Essek, F ^a   Adam Vizi, V ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Brain mitochondria; Free radicals; H2O2 generation; Methylene blue; Mitochondrial membrane potential; Reactive oxygen species; Respiration

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM; CYTOCHROME C; GLUTAMIC ACID DERIVATIVE; GLYCEROPHOSPHATE; HYDROGEN PEROXIDE; METHYLENE BLUE; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; UBIQUINOL CYTOCHROME C REDUCTASE; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ARTICLE; BIOENERGY; BRAIN MITOCHONDRION; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENCEPHALE ISOLE; EXPERIMENTAL GUINEA PIG; FLUOROMETRY; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; RESPIRATORY CHAIN; STEADY STATE; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; DRUG SCREENING; ENERGY METABOLISM; GUINEA PIG; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATION REDUCTION REACTION;

CAVIA;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; DRUG EVALUATION, PRECLINICAL; ENERGY METABOLISM; GUINEA PIGS; HYDROGEN PEROXIDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; METHYLENE BLUE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; OXIDATION-REDUCTION; OXYGEN CONSUMPTION;

EID: 84918495128     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.09.024     Document Type: Article

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