Bioenergetics at low oxygen: Dependence of respiration and phosphorylation on oxygen and adenosine diphosphate supply

Respiration Physiology

Volumn 128, Issue 3, 2001, Pages 277-297

  Gnaiger, E ^a  

^a UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

Author keywords

adenosine diphosphate kinetics; adenosine diphosphate O2 ratio; Energy; heart; Hypoxia; liver; Mammals; Membrane; Mitochondria; mitochondrial O2 kinetics; oxidative phosphorylation; permeability; rat

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; OXYGEN;

AGING; BIOENERGY; BREATHING; CONFERENCE PAPER; HEART MUSCLE METABOLISM; HUMAN; LIVER METABOLISM; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN AFFINITY; OXYGEN CONCENTRATION; OXYGEN CONSUMPTION; OXYGEN DIFFUSION; OXYGEN TENSION; PRIORITY JOURNAL; RESPIRATION CONTROL; RESPIRATORY CHAIN; RESPIROMETRY;

ADENOSINE DIPHOSPHATE; ANIMALS; CELL RESPIRATION; ENERGY METABOLISM; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; OXYGEN; OXYGEN CONSUMPTION;

EID: 0035155343     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(01)00307-3     Document Type: Conference Paper

References (54)

1. The upper and lower limits of the mechanistic stoichiometry of mitochondrial oxidative phosphorylation. Stoichiometry of oxidative phosphorylation
2. Mitochondrial production of superoxide radical and hydrogen peroxide
3. 2 and NO
4. Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes
5. Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase
6. Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization
7. Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function
8. Mitochondrial function in the presence of myoglobin
9. Deciphering the mysteries of myoglobin in striated muscle
10. m for oxygen: implications for mitochondrial pathology
11. Active oxygen species in the liver of rats submitted to chronic hypobaric hypoxia
12. Oxygen dependence of mitochondrial function measured by high-resolution respirometry in long-term hypoxic rats
13. Mechanistic stoichiometry of yeast mitochondrial oxidative phosphorylation
14. The yield of oxidative phosphorylation is controlled both by force and flux
15. 1-sensitive electron spin resonance display
16. On the nature of ion leaks in energy-transducing membranes
17. Does redox slip contribute significantly to mitochondrial respiration?
18. O2 in individual cardiac myocytes in dogs, cats, rabbits, ferrets, and rats
19. Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox?
20. Control of mitochondrial and cellular respiration by oxygen
21. Mitochondrial respiration in the low oxygen environment of the cell. Effect of ADP on oxygen kinetics
22. Mitochondrial oxygen affinity, respiratory flux control, and excess capacity of cytochrome c oxidase
23. Mitochondria in the cold
24. High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia
25. A respirometer for investigating oxidative cell metabolism. Toward optimization of respiratory studies
26. Mechanistic stoichiometry of mitochondrial oxidative phosphorylation
27. Mitochondrial respiratory control. Evidence against the regulation of respiration by extramitochondrial phosphorylation potentials or by [ATP]/[ADP] ratios
28. 2 and ATP
29. Reversible uncoupling of oxidative phosphorylation at low oxygen tension
30. 1H nuclear magnetic resonance signal of myoglobin
31. Aerobic-anoxic transitions and regulation of mitochondrial oxygen flux
32. The ATP-to-oxygen stoichiometries of oxidative phosphorylation by rat liver mitochondria. An analysis of ADP-induced oxygen jumps by linear nonequilibrium thermodynamics
33. How does oxygen pressure control oxygen flux in isolated mitochondria? A methodological approach by high-resolution respirometry and digital data analysis
34. O2 and bioenergetic measurements in skeletal muscle: the role of exercise paradigm
35. High time resolution
36. Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR
37. Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat
38. Interaction of peroxynitrite with mitochondrial cytochrome oxidase: catalytic production of nitric oxide and irreversible inhibition of enzyme activity
39. Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
40. Mitochondrial physiology and pathology; concepts of programmed cell death of organelles, cells and organisms
41. Are mitochondria a permanent source of reactive oxygen species?
42. Oxygen dependence of respiration in coupled and uncoupled endothelial cells
43. Molecular architecture of the rotary motor in ATP synthase
44. - stoichiometries at the individual coupling sites in mitochondrial oxidative phosphorylation. Evidence for maximum values of 1.0, 0.5, and 1.0 at sites 1, 2 and 3
45. Mitochondria as ATP consumers: cellular treason in anoxia
46. 2 affinity of mitochondria in hypoxic hypometabolism
47. 2 supply to mitochondria in actively respiring single cardiomyocyte of rats
48. Kinetic trapping of oxygen in cell respiration
49. Proton translocation by cytochrome c oxidase
50. Quantitative dependence of mitochondrial oxidative phosphorylation on oxygen concentration: a mathematical model
51. Oxygen pressure gradients in isolated cardiac myocytes
52. Transport of oxygen in muscle