Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmissionblocking activity by methylene blue

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 47, 2011, Pages

  Adjalley, Sophie H ^a,d   Johnston, Geoffrey L ^a,b   Li, Tao ^c   Eastman, Richard T ^a,e   Ekland, Eric H ^a   Eappen, Abraham G ^c   Richman, Adam ^c   Sim, B Kim Lee ^c   Lee, Marcus C S ^a   Hoffman, Stephen L ^c   Fidock, David A ^a  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^b Howard Hughes Medical Institute   (United States)

^c SANARIA INC   (United States)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Artemisinin based combination therapies; Transfection

Indexed keywords

ATOVAQUONE; BENFLUMETOL; DEETHYLAMODIAQUINE; DIHYDROARTEMISININ; GREEN FLUORESCENT PROTEIN; LUCIFERASE; METHYLENE BLUE; PIPERAQUINE; PRIMAQUINE; PYRONARIDINE; TAFENOQUINE;

ANOPHELES; ANTIMALARIAL ACTIVITY; ARTICLE; CELL MATURATION; CELL TRANSPORT; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOSE TIME EFFECT RELATION; DRUG MECHANISM; DRUG POTENCY; FEMALE; GAMETOCYTE; GENE EXPRESSION; MALE; NONHUMAN; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; REPORTER GENE; SEXUAL DEVELOPMENT;

AMODIAQUINE; ANIMALS; ANOPHELES; ANTIMALARIALS; ARTEMISININS; BLOTTING, SOUTHERN; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOLAMINES; FLUORENES; GENETIC VECTORS; GERM CELLS, PLANT; GREEN FLUORESCENT PROTEINS; LUCIFERASES; MALARIA; METHYLENE BLUE; NAPHTHYRIDINES; PLASMODIUM FALCIPARUM; QUINOLINES; SEXUAL DEVELOPMENT;

EID: 82755197376     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112037108     Document Type: Article

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