GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity

Circulation Research

Volumn 115, Issue 12, 2014, Pages 976-985

  Hullmann, Jonathan E ^a,b   Grisanti, Laurel A ^b   Makarewich, Catherine A ^b   Gao, Erhe ^b   Gold, Jessica I ^a,b   Chuprun, J Kurt ^b   Tilley, Douglas G ^b   Houser, Steven R ^b   Koch, Walter J ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

G proteincoupled receptor kinase; heart failure; nuclear factor of activated T cells

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 5; GPRK5 PROTEIN, MOUSE; NFATC3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NFAT;

ANIMAL; BINDING SITE; C57BL MOUSE; CARDIAC MUSCLE CELL; CARDIOMEGALY; CELL LINE; CELL NUCLEUS; DISEASE COURSE; DISEASE MODEL; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; MUTATION; PATHOLOGY; PROMOTER REGION; RAT; TIME FACTOR; TRANSGENIC MOUSE;

ANIMALS; BINDING SITES; CARDIOMEGALY; CELL LINE; CELL NUCLEUS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; G-PROTEIN-COUPLED RECEPTOR KINASE 5; GENE EXPRESSION REGULATION; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; RATS; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 84917732136     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.304475     Document Type: Article

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