Notoginsenoside R1 ameliorates podocyte adhesion under diabetic condition through α 3 β 1 integrin upregulation in vitro and in vivo

Cellular Physiology and Biochemistry

Volumn 34, Issue 6, 2014, Pages 1849-1862

  Gui, Dingkun ^a   Wei, Li ^a   Jian, Guihua ^a   Guo, Yongping ^a   Yang, Jiajun ^a   Wang, Niansong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Diabetic condition; Notoginsenoside R1; Oxidative stress; Podocyte adhesion; 3 1 integrin

Indexed keywords

ANTIDIABETIC AGENT; CATALASE; GINSENOSIDE; GLUCOSE; GLUTATHIONE PEROXIDASE; INTEGRIN LINKED KINASE; MALONALDEHYDE; NOTOGINSENOSIDE R1; PROTECTIVE AGENT; STREPTOZOCIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 3;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOSE RESPONSE; DRUG MEGADOSE; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PODOCYTE; PODOCYTE ADHESION; PRIORITY JOURNAL; RAT; RENAL PROTECTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DRUG EFFECTS; GENE EXPRESSION REGULATION; GLOMERULUS BASEMENT MEMBRANE; METABOLISM; PATHOLOGY;

RATTUS;

ANIMALS; CELL ADHESION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; GENE EXPRESSION REGULATION; GINSENOSIDES; GLOMERULAR BASEMENT MEMBRANE; INTEGRIN ALPHA3BETA1; MICE; OXIDATIVE STRESS; PODOCYTES; RATS;

EID: 84917708829     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000366384     Document Type: Article

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