Astragaloside IV improves high glucose-induced podocyte adhesion dysfunction via α3β1 integrin upregulation and integrin-linked kinase inhibition

Biochemical Pharmacology

Volumn 76, Issue 6, 2008, Pages 796-804

  Chen, Jianguo ^a   Gui, Dingkun ^a   Chen, Yifang ^a   Mou, Lijun ^a   Liu, Yi ^b   Huang, Jianhua ^b  

^a ZHEJIANG HOSPITAL   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

3 1 integrin; Astragaloside IV; Diabetic nephropathy; Integrin linked kinase; Podocyte adhesion

Indexed keywords

ASTRAGALOSIDE IV; GLUCOSE; INTEGRIN; MESSENGER RNA; PHOSPHOTRANSFERASE; PROTEIN SUBUNIT; VERY LATE ACTIVATION ANTIGEN 3;

ANIMAL CELL; ARTICLE; ASTRAGALUS MEMBRANACEUS; CELL ADHESION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GLOMERULUS BASEMENT MEMBRANE; IMMUNOBLOTTING; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; CELL ADHESION; CELL LINE, TRANSFORMED; CELLS, CULTURED; GLUCOSE; INTEGRIN ALPHA3BETA1; MICE; PODOCYTES; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; SAPONINS; TRITERPENES; UP-REGULATION;

EID: 50649092654     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.06.020     Document Type: Article

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