Regulation of adhesive interaction between podocytes and glomerular basement membrane

Microscopy Research and Technique

Volumn 57, Issue 4, 2002, Pages 247-253

  Kretzler, Matthias ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Actin; Dystroglycan; Glomerular epithelial cell; Integrin linked kinase; Proteinuria

Indexed keywords

BUILDINGS; ENZYMES; TISSUE CULTURE;

ACTIN; DYSTROGLYCAN; GLOMERULAR BASEMENT MEMBRANE; GLOMERULAR EPITHELIAL CELLS; GLOMERULAR FILTRATION; IN-VITRO; INTEGRIN-LINKED KINASE; INTEGRINS; PODOCYTES; PROTEINURIA;

CELLS;

ACTIN; DYSTROGLYCAN; INTEGRIN; PROTEIN KINASE;

ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL CONTACT; CELL INTERACTION; CELL PROLIFERATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS EPITHELIUM; GLOMERULUS FILTRATION; PHENOTYPE; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEINURIA; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE CULTURE; TRANSGENE;

ANIMALIA;

EID: 0037093539     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.10083     Document Type: Article

References (94)

1. In progressive nephropathies, overload of tubular cells with filtered proteins translates glomerular permeability dysfunction into cellular signals of interstitial inflammation
2. Origin of the glomerular basement membrane visualized after in vivo labeling of laminin in newborn rat kidneys
3. Structure and development of the glomerular capillary wall and basement membrane
4. Characterization of glomerular epithelial cell matrix receptors
5. Integrin receptors in the glomerulus: Potential role in glomerular injury
6. Anti-FxlA antibody recognizes a β1-Integrin on glomerluar epithelial cells and inhibits adhesion and growth
7. Alteration of glomerular permeability to macromolecules induced by cross-linking of beta 1 integrin receptors
8. Cloning and expression of the rat nephrin homolog
9. A quantitative immunofluorescence study of glomerular cell adhesion proteins in proteinuric states
10. Very late activation-3 integrin is the dominant beta 1-integrin on the glomerular capillary wall: An immunofluorescence study in nephrotic syndrome
11. Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies
12. Bi-directional signal transduction by integrin receptors
13. Extracellular matrix as a determinant of signaling responses in glomerular epithelial cells
14. Extracellular matrix regulates proliferation and phospholipid turnover in glomerular epithelial cells
15. Role of extracellular matrix and Ras in regulation of glomerular epithelial cell proliferation
16. Glomerular permeability barrier in the rat. Functional assessment by in vitro methods
17. The receptor for the basement membrane glycoprotein entactin is the integrin alpha 3/beta 1
18. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
19. Activation of mitogenic pathways by albumin in kidney proximal tubule epithelial cells: Implications for the pathophysiology of proteinuric states
20. Structural determinants of glomerular hydraulic permeability
21. Distribution of dystroglycan in normal adult mouse tissues
22. Receptor functions for the integrin VLA-3: Fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations
23. Inside-out signaling through integrins
24. mRNA differential display analysis of nephrotic kidney glomeruli
25. Stretching mesangial cells stimulates tyrosine phosphorylation of focal adhesion kinase pp125FAK
26. Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase
27. Dystroglycan versatility
28. Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney
29. Altered gene expression and functions of mitochondria in human nephrotic syndrome
30. Nephrin localizes to the slit pore of the glomerular epithelial cell
31. Glomerular basement membrane antigens in congenital and acquired nephrotic syndrome in childhood
32. Distribution of integrin subunits in human diabetic kidneys
33. Cloning of rat nephrin: Expression in developing glomeruli and in proteinuric states
34. Podocytes loose their adhesive phenotype in focal segmental glomerulosclerosis
35. Polycation-induced dislocation of slit diaphragms and formation of cell junctions in rat kidney glomeruli: The effects of low temperature, divalent cations, colchicine, and cytochalasin B
36. A beta 1-integrin receptor for fibronectin in human kidney glomeruli
37. Positionally cloned gene for a novel glomerular protein-nephrin is mutated in congenital nephrotic syndrome
38. The alpha 1-alpha 6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron
39. Enhanced expression of the cytoskeleton-associated proteins paxillin and focal adhesion kinase in glomerular immune injury
40. Integrins in kidney development, function, and disease
41. Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis
42. Integrin linked kinase as a common downstream effector in proteinuria
43. Alterations in human glomerular epithelial cells interacting with nonenzymatically glycosylated matrix
44. A frequent pathway to glomerulosclerosis: Deterioration of tuft architecture-podocyte damage-segmental sclerosis
45. The altered glomerular filtration slits seen in puromycin aminonucleoside nephrosis and protamine sulfate-treated rats contain the tight junction protein ZO-1
46. Increased Tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes
47. Assembly of multiple dystrobrevin-containing complexes in the kidney
48. Differential regulation of matrix metalloproteinases and their inhibitors in human glomerular epithelial cells in vitro
49. Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase-9 with enhanced expression in a model of membranous nephropathy
50. Developmental biology of glomerular basement membrane components
51. Renal basement membrane components
52. Evaluation of a new tool for exploring podocyte biology: Mouse nphs1 5′ flanking region drives LacZ expression in podocytes
53. Glomerular overexpression and increased tyrosine phosphorylation of focal adhesion kinase p125FAK in lupus-prone MRL/MP-lpr/lpr mice
54. Phosphorylation of the beta1 integrin cytoplasmic domain: Toward an understanding of function and mechanism
55. Structure and function of podocytes: An update
56. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
57. Characterization of the interactions of alpha-catenin with alpha-actinin and beta-catenin/plakoglobin
58. The renal glomerulus of mice lacking s-laminin/laminin beta 2: Nephrosis despite molecular compensation by laminin beta 1
59. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
60. Nephrotoxic antiserum identifies a beta 1-integrin on rat glomerular epithelial cells
61. Integrin cytoplasmic domains mediate inside-out signal transduction
62. The charge for going by foot: Modifying the surface of podocytes
63. Differential expression of cell-cell and cell-substratum adhesion proteins along the kidney nephron
64. Expression of agrin, dystroglycan, and utrophin in normal renal tissue and in experimental glomerulopathies
65. Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression
66. Glomerular expression of dystroglycans is reduced in minimal change nephrosis but not in focal segmental glomerulosclerosis
67. Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus
68. Expression of beta1 integrins in glomerular tissue of Streptozotocin-induced diabetic rats
69. The glomerular slit diaphragm is a modified adherens junction
70. Regulation of mouse podocyte process dynamics by protein tyrosine phosphatases rapid communication
71. Porous substructure of the glomerular slit diaphragm in the rat and mouse
72. Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies
73. Incomplete fusion of the epithelial and endothelial basement membranes in interspecies hybrid glomeruli
74. Expression of chemokines and their receptors in nephrotoxic serum nephritis
75. Integrin signalling and tyrosine phosphorylation: Just the FAKs?
76. The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium
77. Analysis of mouse glomerular podocyte mRNA by single-cell reverse transcription-polymerase chain reaction
78. Glomerular epithelium: Structural alterations induced by polycations
79. Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: Role in podocyte proliferation and maturation
80. Congenital nephrotic syndrome in mice lacking CD2-associated protein
81. Distribution of extracellular matrix receptors in various forms of glomerulonephritis
82. Cytoskeletal changes in podocytes associated with foot process effacement in Masugi nephritis
83. Cytoskeletal changes in podocytes associates with foot process effacement in Masugi nephritis
84. Regulation of podocyte structure during the development of nephrotic syndrome
85. Podocyte alphaactinin induction precedes foot process effacement in experimental nephrotic syndrome
86. Getting a foothold in nephrotic syndrome
87. Integrin linked kinase regulates podocyte phenotype in vitro
88. Complement-mediated injury reversibly disrupts glomerular epithelial cell actin microfilaments and focal adhesions
89. The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9)
90. Pathological and quantitative morphological changes in the kidney of mice transgenic for growth hormone
91. Podocytic cytoskeletal disaggregation and basement-membrane detachment in puromycin aminonucleoside nephrosis
92. Identification and characterization of a glomerular-specific promoter from the human nephrin gene
93. Integrin-linked protein kinase regulates fibronectin matrix assembly. E-cadherin expression, and tumorigenicity
94. Integrin-linked protein kinase regulates fibronectin matrix assembly. E-cadherin expression, and tumorigenicity