메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages

Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CARDIOVASCULAR AGENT; CHOLESTEROL; GAMMA INTERFERON; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 2; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN; MALATE DEHYDROGENASE; MICRORNA; MICRORNA 126; MICRORNA 126A; MICRORNA 132; MICRORNA 146; MICRORNA 155; MICRORNA 20A; MICRORNA 21; MICRORNA 26A; MICRORNA 92A; NOTOGINSENOSIDE R1; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE; GINSENOSIDE; LIPID;

EID: 84903135425     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099849     Document Type: Article
Times cited : (65)

References (35)
  • 1
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ (2000) Atherosclerosis. Nature 407: 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 2
    • 1942428112 scopus 로고    scopus 로고
    • Reverse cholesterol transport: High-density lipoprotein's magnificent mile
    • Toth PP (2003) Reverse cholesterol transport: high-density lipoprotein's magnificent mile. Curr Atheroscler Rep 5: 386-393.
    • (2003) Curr Atheroscler Rep , vol.5 , pp. 386-393
    • Toth, P.P.1
  • 3
    • 1942470461 scopus 로고    scopus 로고
    • High-Density Lipoprotein and Cardiovascular Risk
    • Toth PP (2004) High-Density Lipoprotein and Cardiovascular Risk. Circulation 109: 1809-1812.
    • (2004) Circulation , vol.109 , pp. 1809-1812
    • Toth, P.P.1
  • 4
    • 84867798454 scopus 로고    scopus 로고
    • Cardiovascular disease risk reduction by raising HDL cholesterol-current therapies and future opportunities
    • Mahdy Ali K, Wonnerth A, Huber K, Wojta J (2012) Cardiovascular disease risk reduction by raising HDL cholesterol-current therapies and future opportunities. Br J Pharmacol 167: 1177-1194.
    • (2012) Br J Pharmacol , vol.167 , pp. 1177-1194
    • Mahdy Ali, K.1    Wonnerth, A.2    Huber, K.3    Wojta, J.4
  • 5
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 7
    • 84865444770 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: A cause or a result of vascular disorders?
    • Manduteanu I, Simionescu M (2012) Inflammation in atherosclerosis: a cause or a result of vascular disorders? J Cell Mol Med 16: 1978-1990.
    • (2012) J Cell Mol Med , vol.16 , pp. 1978-1990
    • Manduteanu, I.1    Simionescu, M.2
  • 9
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • DOI 10.1038/nrg1379
    • He L, Hannon GJ (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-531. (Pubitemid 38868508)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 10
    • 79960175448 scopus 로고    scopus 로고
    • MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis
    • Hulsmans M, De Keyzer D, Holvoet P (2011) MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis. Faseb J 25: 2515-2527.
    • (2011) Faseb J , vol.25 , pp. 2515-2527
    • Hulsmans, M.1    De Keyzer, D.2    Holvoet, P.3
  • 11
    • 84885187417 scopus 로고    scopus 로고
    • Oxidative stress in atherosclerosis: The role of microRNAs in arterial remodeling
    • Zampetaki A, Dudek K, Mayr M (2013) Oxidative stress in atherosclerosis: the role of microRNAs in arterial remodeling. Free Radic Biol Med 64: 69-77.
    • (2013) Free Radic Biol Med , vol.64 , pp. 69-77
    • Zampetaki, A.1    Dudek, K.2    Mayr, M.3
  • 13
    • 48149106680 scopus 로고    scopus 로고
    • Effects of four medicinal herbs on human vascular endothelial cells in culture
    • Ling S, Nheu L, Dai A, Guo Z, Komesaroff P (2008) Effects of four medicinal herbs on human vascular endothelial cells in culture. Int J Cardiol 128: 350-358.
    • (2008) Int J Cardiol , vol.128 , pp. 350-358
    • Ling, S.1    Nheu, L.2    Dai, A.3    Guo, Z.4    Komesaroff, P.5
  • 14
    • 84861379440 scopus 로고    scopus 로고
    • Panax notogingseng saponins suppress RAGE/MAPK signaling and NF-kappaB activation in apolipoprotein-E-deficient atherosclerosis-prone mice
    • Dou L, Lu Y, Shen T, Huang X, Man Y, et al. (2012) Panax notogingseng saponins suppress RAGE/MAPK signaling and NF-kappaB activation in apolipoprotein-E-deficient atherosclerosis-prone mice. Cell Physiol Biochem 29: 875-882.
    • (2012) Cell Physiol Biochem , vol.29 , pp. 875-882
    • Dou, L.1    Lu, Y.2    Shen, T.3    Huang, X.4    Man, Y.5
  • 15
    • 68249118235 scopus 로고    scopus 로고
    • Panax notoginseng reduces atherosclerotic lesions in ApoE-deficient mice and inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion
    • Wan JB, Lee SM, Wang JD, Wang N, He CW, et al. (2009) Panax notoginseng reduces atherosclerotic lesions in ApoE-deficient mice and inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion. J Agric Food Chem 57: 6692-6697.
    • (2009) J Agric Food Chem , vol.57 , pp. 6692-6697
    • Wan, J.B.1    Lee, S.M.2    Wang, J.D.3    Wang, N.4    He, C.W.5
  • 16
    • 84875123671 scopus 로고    scopus 로고
    • Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: An insight into oestrogen receptor activation and PI3K/Akt signalling
    • Sun B, Xiao J, Sun XB, Wu Y (2013) Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into oestrogen receptor activation and PI3K/Akt signalling. Br J Pharmacol 168: 1758-1770.
    • (2013) Br J Pharmacol , vol.168 , pp. 1758-1770
    • Sun, B.1    Xiao, J.2    Sun, X.B.3    Wu, Y.4
  • 17
    • 77955977727 scopus 로고    scopus 로고
    • Notoginsenoside R1 attenuates renal ischemia-reperfusion injury in rats
    • Liu WJ, Tang HT, Jia YT, Ma B, Fu JF, et al. (2010) Notoginsenoside R1 attenuates renal ischemia-reperfusion injury in rats. Shock 34: 314-320.
    • (2010) Shock , vol.34 , pp. 314-320
    • Liu, W.J.1    Tang, H.T.2    Jia, Y.T.3    Ma, B.4    Fu, J.F.5
  • 18
    • 84892600718 scopus 로고    scopus 로고
    • Protective effects of Notoginsenoside R1 on intestinal ischemia-reperfusion injury in rats
    • Li C, Li Q, Liu YY, Wang MX, Pan CS, et al. (2014) Protective effects of Notoginsenoside R1 on intestinal ischemia-reperfusion injury in rats. Am J Physiol Gastrointest Liver Physiol 306: G111-122.
    • (2014) Am J Physiol Gastrointest Liver Physiol , vol.306
    • Li, C.1    Li, Q.2    Liu, Y.Y.3    Wang, M.X.4    Pan, C.S.5
  • 19
    • 0030978115 scopus 로고    scopus 로고
    • Notoginsenoside R1 counteracts endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo
    • Zhang WJ, Wojta J, Binder BR (1997) Notoginsenoside R1 counteracts endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo. Arterioscler Thromb Vasc Biol 17: 465-474. (Pubitemid 27133135)
    • (1997) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.17 , Issue.3 , pp. 465-474
    • Zhang, W.-J.1    Wojta, J.2    Binder, B.R.3
  • 21
    • 34547791216 scopus 로고    scopus 로고
    • Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats
    • DOI 10.1016/j.jep.2007.06.022, PII S0378874107003121
    • Ji W, Gong BQ (2007) Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats. J Ethnopharmacol 113: 318-324. (Pubitemid 47239259)
    • (2007) Journal of Ethnopharmacology , vol.113 , Issue.2 , pp. 318-324
    • Ji, W.1    Gong, B.Q.2
  • 22
    • 84902135938 scopus 로고    scopus 로고
    • Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways
    • Meng X, Wang M, Wang X, Sun G, Ye J, et al. (2014) Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways. Free Radic Res 7: 7.
    • (2014) Free Radic Res , vol.7 , pp. 7
    • Meng, X.1    Wang, M.2    Wang, X.3    Sun, G.4    Ye, J.5
  • 23
    • 84895762922 scopus 로고    scopus 로고
    • Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: A novel mechanism of Nrf2/ARE signaling activation
    • Meng X, Sun G, Ye J, Xu H, Wang H, et al. (2014) Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: a novel mechanism of Nrf2/ARE signaling activation. Free Radic Res 48: 445-460.
    • (2014) Free Radic Res , vol.48 , pp. 445-460
    • Meng, X.1    Sun, G.2    Ye, J.3    Xu, H.4    Wang, H.5
  • 26
    • 76749170274 scopus 로고    scopus 로고
    • Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation
    • Forrest AR, Kanamori-Katayama M, Tomaru Y, Lassmann T, Ninomiya N, et al. (2010) Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia 24: 460-466.
    • (2010) Leukemia , vol.24 , pp. 460-466
    • Forrest, A.R.1    Kanamori-Katayama, M.2    Tomaru, Y.3    Lassmann, T.4    Ninomiya, N.5
  • 28
    • 77957279894 scopus 로고    scopus 로고
    • MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts
    • Zheng L, Xu CC, Chen WD, Shen WL, Ruan CC, et al. (2010) MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts. Biochem Biophys Res Commun 400: 483-488.
    • (2010) Biochem Biophys Res Commun , vol.400 , pp. 483-488
    • Zheng, L.1    Xu, C.C.2    Chen, W.D.3    Shen, W.L.4    Ruan, C.C.5
  • 29
    • 67649349865 scopus 로고    scopus 로고
    • MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages
    • Chen T, Huang Z, Wang L, Wang Y, Wu F, et al. (2009) MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages. Cardiovasc Res 83: 131-139.
    • (2009) Cardiovasc Res , vol.83 , pp. 131-139
    • Chen, T.1    Huang, Z.2    Wang, L.3    Wang, Y.4    Wu, F.5
  • 30
    • 77954758345 scopus 로고    scopus 로고
    • Short communication: Asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism
    • Fleissner F, Jazbutyte V, Fiedler J, Gupta SK, Yin X, et al. (2010) Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21- dependent mechanism. Circ Res 107: 138-143.
    • (2010) Circ Res , vol.107 , pp. 138-143
    • Fleissner, F.1    Jazbutyte, V.2    Fiedler, J.3    Gupta, S.K.4    Yin, X.5
  • 31
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
    • DOI 10.1161/CIRCRESAHA.106.141986
    • Ji R, Cheng Y, Yue J, Yang J, Liu X, et al. (2007) MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res 100: 1579-1588. (Pubitemid 46897261)
    • (2007) Circulation Research , vol.100 , Issue.11 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 32
    • 79251520968 scopus 로고    scopus 로고
    • MicroRNA-26a is a novel regulator of vascular smooth muscle cell function
    • Leeper NJ, Raiesdana A, Kojima Y, Chun HJ, Azuma J, et al. (2011) MicroRNA-26a is a novel regulator of vascular smooth muscle cell function. J Cell Physiol 226: 1035-1043.
    • (2011) J Cell Physiol , vol.226 , pp. 1035-1043
    • Leeper, N.J.1    Raiesdana, A.2    Kojima, Y.3    Chun, H.J.4    Azuma, J.5
  • 33
    • 34447632218 scopus 로고    scopus 로고
    • Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis
    • DOI 10.1161/CIRCRESAHA.107.153916, PII 0000301220070706000008
    • Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S (2007) Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res 101: 59-68. (Pubitemid 47094624)
    • (2007) Circulation Research , vol.101 , Issue.1 , pp. 59-68
    • Kuehbacher, A.1    Urbich, C.2    Zeiher, A.M.3    Dimmeler, S.4
  • 34
    • 77955384669 scopus 로고    scopus 로고
    • MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
    • Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, et al. (2010) MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med 16: 909-914.
    • (2010) Nat Med , vol.16 , pp. 909-914
    • Anand, S.1    Majeti, B.K.2    Acevedo, L.M.3    Murphy, E.A.4    Mukthavaram, R.5
  • 35
    • 67649998366 scopus 로고    scopus 로고
    • MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice
    • Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, et al. (2009) MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science 324: 1710-1713.
    • (2009) Science , vol.324 , pp. 1710-1713
    • Bonauer, A.1    Carmona, G.2    Iwasaki, M.3    Mione, M.4    Koyanagi, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.