Notoginsenoside R1 attenuates renal ischemia-reperfusion injury in rats

Shock

Volumn 34, Issue 3, 2010, Pages 314-320

  Liu, Wen Jun ^a,b   Tang, Hong Tai ^a   Jia, Yi Tao ^a   Ma, Bing ^a   Fu, Jin Feng ^b   Wang, Yu ^a   Lv, Kai Yang ^a   Xia, Zhao Fan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; bcl 2; inflammation; ischemia reperfusion injury; kidney; NF B; Notoginsenoside R1; p38MAPK

Indexed keywords

CREATININE; GINSENOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; NOTOGINSENOSIDE R1; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE COMPARISON; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HISTOLOGY; IMMUNOSTIMULATION; INFLAMMATION; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; MALE; NEPHRECTOMY; NONHUMAN; PANAX NOTOGINSENG; RAT; REPERFUSION INJURY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; CREATININE; CYTOKINES; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; GENES, BCL-2; GINSENOSIDES; KIDNEY; MALE; NEUTROPHILS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEROXIDASE; PROTO-ONCOGENE PROTEINS C-BCL-2; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; REPERFUSION INJURY;

EID: 77955977727     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181ceede4     Document Type: Article

References (38)

1. Boros P, Bromberg JS: New cellular and molecular immune pathways in ischemia/reperfusion injury. Am J Transplant 6:652-658, 2006.
2. Einecke G, Melk A, Ramassar V, Zhu LF, Bleackley RC, Famulski KS, Halloran PF: Expression of CTL associated transcripts precedes the development of tubulitis in T-cell mediated kidney graft rejection. Am J Transplant 5:1827-1836, 2005.
3. Thadhani R, Pascual M, Bonventre JV: Acute renal failure. N Engl J Med 334:1448-1460, 1996.
4. Xia ZF, He F, Barrow RE, Broemeling LD, Herndon DN: Reperfusion injury in burned rats after delayed fluid resuscitation. J Burn Care Rehabil 12:430-436, 1991.
5. Vinas JL, Hotter G, Pi F, Palacios L, Sola A: Role of peroxynitrite on cytoskeleton alterations and apoptosis in renal ischemia reperfusion. Am J Physiol Renal Physiol 292:F1673-F1680, 2007.
6. Chiang-Ting C, Tzu-Ching C, Ching-Yi T, Song-Kuen S, Ming-Kuen L: Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia/reperfusion induced tubular oxidative stress and apoptosis. Am J Transplant 5:1194-1203, 2005.
7. Rodriguez-Pena A, Garcia-Criado FG, Eleno N, Arevalo M, Lopez-Novoa JM: Intrarenal administration of molsidomine, a molecule releasing nitric oxide, reduces renal ischemia-reperfusion injury in rats. Am J Transplant 4:1605-1613, 2004.
8. Runembert I, Couette S, Federici P, Colucci-Guyon E, Babinet C, Briand P, Friedlander G, Terzi F: Recovery of Na-glucose cotransport activity after renal ischemia is impaired in mice lacking vimentin. Am J Physiol Renal Physiol 287:F960-F968, 2004.
9. Dragun D, Hoff U, Park JK, Qun Y, Schneider W, Luft FC, Haller H: Ischemia-reperfusion injury in renal transplantation is independent of the immunologic background. Kidney Int 58:2166-2177, 2004.
10. El-Sawy T, Miura M, Fairchild R: Early T cell response to allografts occurring prior to alloantigen priming up-regulates innate-mediated inflammation and graft necrosis. Am J Pathol 165:147-157, 2004.
11. Daemen MA, De Vries B, Buurman WA: Apoptosis and inflammation in renal reperfusion injury. Transplantation 73:1693-1700, 2002.
12. Xie J, Guo Q: Apoptosis antagonizing transcription factor protects renal tubule cells against oxidative damage and apoptosis induced by ischemia-reperfusion. J Am Soc Nephrol 17:3336-3346, 2006.
13. Feng L, Xiong Y, Cheng F, Zhang L, Li S, Li Y: Effect of ligustrazine on ischemia-reperfusion injury in murine kidney. Transplant Proc 36:1949-1951, 2004.
14. Chen WX, Wang F, Liu YY, Zeng QJ, Sun K, Xue X, Li X, Yang JY, An LH, Hu BH, et al.: Effect of notoginsenoside R1 on hepatic microcirculation disturbance induced by gut ischemia and reperfusion. World J Gastroenterol 14:29-37, 2008.
15. Zhang WJ, Wojta J, Binder BR: Notoginsenoside R1 counteracts endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo. Arterioscler Thromb Vasc Biol 17:465-474, 1997.
16. Zhang HS, Wang SQ: Notoginsenoside R1 inhibits TNF-alphaYinduced fibronectin production in smooth muscle cells via the ROS/ERK pathway. Free Radic Biol Med 40:1664-1674, 2006.
17. Sun K, Wang CS, Guo J, Liu YY, Wang F, Liu LY, He JG, Fan JY, Han JY: Effect of Panax notoginseng saponins on lipopolysaccharide-induced adhesion of leukocytes in rat mesenteric venules. Clin Hemorheol Microcirc 34:103-108, 2006.
18. Joo SS, Won TJ, Lee DI: Reciprocal activity of ginsenosides in the production of proinflammatory repertoire, and their potential roles in neuroprotection in vivo. Planta Med 71:476-481, 2005.
19. Wang Y, Peng D, Huang W, Zhou X, Liu J, Fang Y: Mechanism of altered TNF-alpha expression by macrophage and the modulatory effect of Panax notoginseng saponins in scald mice. Burns 32:846-852, 2006.
20. Chatterjee PK, Patel NS, Sivarajah A, Kvale EO, Dugo L, Cuzzocrea S, Brown PA, Stewart KN, Mota-Filipe H, Britti D, et al.: GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int 63:853-865, 2003
21. Patel NS, Sharples EJ, Cuzzocrea S, Chatterjee PK, Britti D, Yaqoob MM, Thiemermann C: Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. Kidney Int 66:983-989, 2004.
22. Jia YT, Ma B, Wei W, Xu Y, Wang Y, Tang HT, Xia ZF: Sustained activation of nuclear factor-kappaB by reactive oxygen species is involved in the patho-genesis of stress-induced gastric damage in rats. Crit Care Med 35:1582-1591, 2007.
23. Chen XL, Xia ZF, Ben DF, Wang GQ, Wei D: Role of p38 mitogen-activated protein kinase in lung injury after burn trauma. Shock 19:475-479, 2003.
24. Basile DP, Liapis H, Hammerman MR: Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury. Am J Physiol 272:F640-F647, 1997.
25. Ysebaert DK, De Greef KE, De Beuf A, Van Rompay AR, Vercauteren S, Persy VP, De Broe ME: T cells as mediators in renal ischemia/reperfusion injury. Kidney Int 66:491-496, 2004.
26. Azuma H, Nadeau K, Takada M, Mackenzie HS, Tilney NL: Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/reperfusion injury of a single kidney. Transplantation 64:190-197, 1997.
27. Donnahoo KK, Meng X, Ayala A, Cain MP, Harken AH, Meldrum DR: Early kidney TNF-alpha expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion. Am J Physiol 277:R922-R929, 1999.
28. Meldrum KK, Meldrum DR, Meng X, Ao L, Harken AH: TNF-alphaYdependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion. Am J Physiol Heart Circ Physiol 282:H540-H546, 2002.
29. Bilbao G, Contreras JL, Eckhoff DE, Mikheeva G, Krasnykh V, Douglas JT, Thomas FT, Thomas JM, Curiel DT: Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene. Ann Surg 230:185-193, 1999.
30. Loverre A, Ditonno P, Crovace A, Gesualdo L, Ranieri E, Pontrelli P, Stallone G, Infante B, Schena A, Di Paolo S, et al.: Ischemia-reperfusion induces glo-merular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin. J Am Soc Nephrol 15:2675-2686, 2004.
31. Birbach A, Gold P, Binder BR, Hofer E, De Martin R, Schmid JA: Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus. J Biol Chem 277:10842-10851, 2002.
32. Furuichi K, Wada T, Iwata Y, Sakai N, Yoshimoto K, Kobayashi Ki K, Mukaida N, Matsushima K, Yokoyama H: Administration of FR167653, a new anti-inflammatory compound, prevents renal ischaemia/reperfusion injury in mice. Nephrol Dial Transplant 17:399-407, 2002.
33. Kim JH, Yang JI, Jung MH, Hwa JS, Kang KR, Park DJ, Roh GS, Cho GJ, Choi WS, Chang SH: Heme oxygenase-1 protects rat kidney from ureteral obstruction via an antiapoptotic pathway. J Am Soc Nephrol 17:1373-1381, 2006.
34. Li J, Deane JA, Campanale NV, Bertram JF, Ricardo SD: Blockade of p38 mitogen-activated protein kinase and TGF-beta1/Smad signaling pathways rescues bone marrow-derived peritubular capillary endothelial cells in adriamycin-induced nephrosis. J Am Soc Nephrol 17:2799-2811, 2006.
35. Kang DG, Sohn EJ, Moon MK, Mun YJ, Woo WH, Kim MK, Lee HS: Yukmijihwang-tang ameliorates ischemia/reperfusionYinduced renal injury in rats. J Ethnopharmacol 104:47-53, 2006.
36. Callaghan CJ, Bradley JA: Current status of renal transplantation. Methods Mol Biol 333:1-28, 2006.
37. Kaplan B, Srinivas TR, Meier-Kriesche HU: Factors associated with long-term renal allograft survival. Ther Drug Monit 24:36-39, 2002.
38. McTaggart RA, Gottlieb D, Brooks J, Bacchetti P, Roberts JP, Tomlanovich S, Feng S: Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. Am J Transplant 3:416-423, 2003.