Subretinal injection of amyloid-β peptide acceleratesRPE cell senescence and retinal degeneration

International Journal of Molecular Medicine

Volumn 35, Issue 1, 2015, Pages 169-176

  Liu, Chaoqi ^a   Cao, Lining ^a   Yang, Shuai ^a   Xu, Linxinyu ^a   Liu, Pei ^a   Wang, Fang ^a   Xu, Ding ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Age related macular degeneration; Inflammation; Retinal pigment epithelium; Senescence

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

A WAVE; AGE RELATED MACULAR DEGENERATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; B WAVE; BRUCH MEMBRANE; C WAVE; CELL AGING; CELL VACUOLE; CHOROID; CHRONIC INFLAMMATION; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EYE FUNDUS; EYE PHOTOGRAPHY; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INFLAMMATION; MORPHOLOGICAL TRAIT; MOUSE; NONHUMAN; PERFUSION; PHOTORECEPTOR INNER SEGMENT; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; PROTEIN FOLDING; REAL TIME POLYMERASE CHAIN REACTION; RETINA DEGENERATION; RETINA NEUROEPITHELIAL LAYER; RETINA ROD OUTER SEGMENT; RETINAL THICKNESS; SCANNING LASER OPHTHALMOSCOPY; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; VISION; WESTERN BLOTTING; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RETINAL DEGENERATION; ULTRASTRUCTURE;

AMYLOID BETA-PEPTIDES; ANIMALS; CELL AGING; CYTOKINES; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; GENE EXPRESSION; MICE; PEPTIDE FRAGMENTS; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER; VISION, OCULAR;

EID: 84917698555     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1993     Document Type: Article

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