Subretinal injections in rodent eyes: Effects on electrophysiology and histology of rat retina

Molecular Vision

Volumn 7, Issue , 2001, Pages 131-137

  Timmers, Adrian M ^a   Zhang, Hong ^a   Squitieri, Alicia ^a   Gonzalez Pola, Carlos ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; B WAVE; CATARACT; CONTROLLED STUDY; CORNEA; ELECTROPHYSIOLOGY; ELECTRORETINOGRAPHY; HISTOLOGY; INJECTION; INTRAOCULAR DRUG ADMINISTRATION; NEEDLE; NONHUMAN; PHAGOCYTOSIS; PIGMENT EPITHELIUM; PUNCTURE; RAT; RELIABILITY; RETINA; RODENT; SUBRETINAL DRUG ADMINISTRATION; TECHNIQUE;

ANIMALS; ELECTRORETINOGRAPHY; FLUORESCEIN; FUNDUS OCULI; INJECTIONS; MALE; MICROSPHERES; OPHTHALMOLOGIC SURGICAL PROCEDURES; RATS; RATS, SPRAGUE-DAWLEY; RETINA;

EID: 0035789070     PISSN: 10900535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Hauswirth WW, Lewin AS, Zolotukhin S, Muzyczka N. Production and purification of recombinant adeno-associated virus. Methods Enzymol 2000; 316:743-61.
2. Guy J, Qi X, Muzyczka N, Hauswirth WW. Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve. Arch Ophthalmol 1999; 117:929-37.
3. Guy J, Qi X, Hauswirth WW. Adeno-associated viral-mediated catalase expression suppresses optic neuritis in experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A 1998; 95:13847-52.
4. Lewin AS, Drenser KA, Hauswirth WW, Nishikawa S, Yasumura D, Flannery JG, La Vail MM. Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nat Med 1998; 4:967-71.
5. Flannery JG, Zolotukhin S, Vaquero MI, La Vail MM, Muzyczka N, Hauswirth WW. Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus. Proc Natl Acad Sci U S A 1997; 94:6916-21.
6. Zolotukhin S, Potter M, Hauswirth WW, Guy J, Muzyczka N. A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells. J Virol 1996; 70:4646-54.
7. Bennett J, Maguire AM. Gene therapy for ocular disease. Mol Ther 2000; 1:501-5.
8. Bennett J, Anand V, Acland GM, Maguire AM. Cross-species comparison of in vivo reporter gene expression after recombinant adeno-associated virus-mediated retinal transduction. Methods Enzymol 2000; 316:777-89.
9. Anand V, Chirmule N, Fersh M, Maguire AM, Bennett J. Additional transduction events after subretinal readministration of recombinant adeno-associated virus. Hum Gene Ther 2000; 11:449-57.
10. Bennett J, Maguire AM, Cideciyan AV, Schnell M, Glover E, Anand V, Aleman TS, Chirmule N, Gupta AR, Huang Y, Gao GP, Nyberg WC, Tazelaar J, Hughes J, Wilson JM, Jacobson SG. Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. Proc Natl Acad Sci U S A 1999; 96:9920-5.
11. Bennett J, Duan D, Engelhardt JF, Maguire AM. Real-time, noninvasive in vivo assessment of adeno-associated virus-mediated retinal transduction. Invest Ophthalmol Vis Sci 1997; 38:2857-63.
12. Ali RR, Sarra GM, Stephens C, Alwis MD, Bainbridge JW, Munro PM, Fauser S, Reichel MB, Kinnon C, Hunt DM, Bhattacharya SS, Thrasher AJ. Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy. Nat Genet 2000; 25:306-10.
13. Ali RR, Reichel MB, De Alwis M, Kanuga N, Kinnon C, Levinsky RJ, Hunt DM, Bhattacharya SS, Thrasher AJ. Adeno-associated virus gene transfer to mouse retina. Hum Gene Ther 1998; 9:81-6.
14. Reichel MB, Ali RR, Hunt DM, Bhattacharya SS. Gene therapy for retinal degeneration. Ophthalmic Res 1997; 29:261-8.
15. Ali RR, Reichel MB, Thrasher AJ, Levinsky RJ, Kinnon C, Kanuga N, Hunt DM, Bhattacharya SS. Gene transfer into the mouse retina mediated by an adeno-associated viral vector. Hum Mol Genet 1996; 5:591-4.
16. Takahashi M, Miyoshi K, Verma IM, Gage FH. Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer. J Virol 1999; 73:7812-6.
17. Miyoshi H, Takahashi M, Gage FH, Verma IM. Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A 1997; 94:10319-23.
18. Cayouette M, Behn D, Sendtner M, Lachapelle P, Gravel C. Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. J Neurosci 1998; 18:9282-93.
19. Cayouette M, Gravel C. Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse. Hum Gene Ther 1997; 8:423-30.
20. Rakoczy PE, Shen WY, Lai M, Rolling F, Constable IJ. Development of gene therapy-based strategies for the treatment of eye diseases. Drug Development Research 1999; 46:277-85.
21. Rolling F, Shen WY, Tabarias H, Constable I, Kanagasingam Y, Barry CJ, Rakoczy PE. Evaluation of adeno-associated virus-mediated gene transfer into the rat retina by clinical fluorescence photography. Hum Gene Ther 1999; 10:641-8.
22. Rakoczy PE, Lai MC, Baines MG, Spilsbury K, Constable IJ. Expression of cathepsin S antisense transcripts by adenovirus in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1998; 39:2095-104.
23. da Cruz L, Rakoczy PE, Constable IJ. Expression of transgenes in human and rat retinal pigment epithelium in vitro using an adenoviral vector. Aust N Z J Ophthalmol 1996; 24:78-81.
24. da Cruz L, Rakoczy P, Perricaudet M, Constable IJ. Dynamics of gene transfer to retinal pigment epithelium. Invest Ophthalmol Vis Sci 1996; 37:2447-54.
25. Price J, Turner D, Cepko C. Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer. Proc Natl Acad Sci U S A 1987; 84:156-60.
26. Turner DL, Cepko CL. A common progenitor for neurons and glia persists in rat retina late in development. Nature 1987; 328:131-6.
27. Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, La Vail MM. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature 1990; 347:83-6.
28. Silverman MS, Hughes SE. Photoreceptor rescue in the RCS rat without pigment epithelium transplantation. Curr Eye Res 1990; 9:183-91.
29. Hawes NL, Smith RS, Chang B, Davisson M, Heckenlively JR, John SW. Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Mol Vis 1999; 5:22 .
30. Bayer AU, Mittag T, Cook P, Brodie SE, Podos SM, Maag KP. Comparisons of the amplitude size and the reproducibility of three different electrodes to record the corneal flash electroretinogram in rodents. Doc Ophthalmol 1999; 98:233-46.
31. Kirkness CM. Do ophthalmic instruments pose a hazard of light-induced damage to the eye? In: Cronly-Dillon J, Rosen ES, Marshall J, editors. Hazards of light: myths and reality. Eye and skin. Proceedings of the First International Symposium of the Northern Eye Institute; 1985 July; Manchester, England. Oxford: Pergamon Press; 1986. p. 179-86.