Protein supplementation with aging

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 18, Issue 1, 2015, Pages 24-31

  Bauer, Juergen M ^a   Diekmann, Rebecca ^a  

^a UNIVERSITY OF OLDENBURG   (Germany)

Author keywords

Amino acids; Elderly; Functionality; Protein; Supplementation

Indexed keywords

LEUCINE; MILK PROTEIN; MUSCLE PROTEIN; PROTEIN INTAKE;

AGING; CHRONIC KIDNEY DISEASE; COMORBIDITY; DIET SUPPLEMENTATION; EXERCISE; FRAIL ELDERLY; HUMAN; MUSCLE FUNCTION; MUSCLE MASS; MUSCLE STRENGTH; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PROTEIN INTAKE; PROTEIN SYNTHESIS; REVIEW; SARCOPENIA; WHEY; DRUG EFFECTS; METABOLISM; PHARMACOLOGY; SKELETAL MUSCLE; THERAPEUTIC USE;

AGING; DIETARY PROTEINS; DIETARY SUPPLEMENTS; EXERCISE; HUMANS; MUSCLE PROTEINS; MUSCLE STRENGTH; MUSCLE, SKELETAL; PROTEIN BIOSYNTHESIS;

EID: 84916614253     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0000000000000124     Document Type: Review

References (61)

1. Beasley JM, LaCroix AZ, Neuhouser ML, et al. Protein intake and incident frailty in the Women's Health Initiative observational study. J Am Geriatr Soc 2010; 58: 1063-1071.
2. Houston DK, Nicklas BJ, Ding J, et al. Dietary protein intake is associated with lean mass change in older, community-dwelling adults: The Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr 2008; 87: 150-155.
3. Bauer J, Biolo G, Cederholm T, et al. Evidence-based recommendations for optimal dietary protein intake in older people: A position paper from the PROT-AGE Study Group. J Am Med Dir Assoc 2013; 14: 542-559.
4. Deutz NE, Bauer JM, Barazzoni R, et al. Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group. Clin Nutr 2014. [Epub ahead of print
5. Rizzoli R, Stevenson JC, Bauer JM, et al. The role of dietary protein and vitaminD in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas 2014; 79: 122-132.
6. World Health Organization. Protein and amino acid requirements in human nutrition: Report of a Joint WHO/FAO/UNU expert consultation. WHO Press; 2007 ; http://whqlibdoc.who.int/trs/who-trs-935-eng.pdf. [Accessed 15 October 2014
7. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids (macronutrients). http://www.nap.edu/openbook.php?record-id=10490. [Accessed 4 August 2014
8. Deutsche Gesellschaft für Ernährung. D-A-CH Referenzwerte. Referenzwerte für die Nährstoffzufuhr. 1. Auflage, 5., korrigierter Nachdruck 2013. [German Society for Nutrition. D-A-C-H reference values
9. European Food Safety Authority. Scientific opinion on dietary reference values for protein. EFSA Journal 2012; 10: 2557. http://www.efsa.europa.eu/de/efsajournal/doc/2557.pdf.
10. Tang M, McCabe GP, Elango R, et al. Assessment of protein requirement in octogenarian women with use of the indicator amino acid oxidation technique. Am J Clin Nutr 2014; 99: 891-898.
11. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European WorkingGroup on Sarcopenia in Older People. Age Ageing 2010; 39: 412-423.
12. Beasley JM, Wertheim BC, LaCroix AZ, et al. Biomarker-calibrated protein intake and physical function in the Women's Health Initiative. J Am Geriatr Soc 2013; 61: 1863-1871.
13. Kanis JA, McCloskey EV, Johansson H, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 2013; 24: 23-57.
14. Beasley JM, LaCroix AZ, Larson JC, et al. Biomarker-calibrated protein intake and bone health in the Women's Health Initiative clinical trials and observational study. Am J Clin Nutr 2014; 99: 934-940.
15. Fulgoni VL 3rd. Current protein intake in America: Analysis of the National Health and Nutrition Examination Survey, 2003-2004. Am J Clin Nutr 2008; 87: 1554S-1557S.
16. EisingerM. MicrosoftWord -NVSII-Ergebnisbericht-Teil2-Sep08.doc.http://www.was-esse-ich.de/uploads/media/NVSII-Abschlussbericht-Teil-2.pdf.
17. Tieland M, Borgonjen-Van Den Berg KJ, van Loon LJ, de Groot LC. Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: Scope for improvement. Eur J Nutr 2012; 51: 173-179.
18. Vikstedt T, Suominen MH, Joki A, et al. Nutritional status, energy, protein, and micronutrient intake of older service house residents. J Am Med Dir Assoc 2011; 12: 302-307.
19. Volpi E, Campbell WW, Dwyer JT, et al. Is the optimal level of protein intake for older adults greater than the recommended dietary allowance? J Gerontol A Biol Sci Med Sci 2013; 68: 677-681.
20. Walrand S, Short KR, Bigelow ML, et al. Functional impact of high protein intake on healthy elderly people. Am J Physiol Endocrinol Metab 2008; 295: E921-E928.
21. Symons TB, Sheffield-Moore M, Wolfe RR, et al. A moderate serving of highquality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc 2009; 109: 1582-1586.
22. Mamerow MM, Mettler JA, English KL, et al. Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults. J Nutr 2014; 144: 876-880.
23. Bollwein J, Diekmann R, Kaiser MJ, et al. Distribution but not amount of protein intake is associated with frailty: A cross-sectional investigation in the region of Nurnberg. Nutr J 2013; 12: 109.
24. Deutz NE, Wolfe RR. Is there a maximal anabolic response to protein intake with a meal? Clin Nutr 2013; 32: 309-313.
25. Bouillanne O, Curis E, Hamon-Vilcot B, et al. Impact of protein pulse feeding on lean mass in malnourished and at-risk hospitalized elderly patients: A randomized controlled trial. Clin Nutr 2013; 32: 186-192.
26. Paddon-Jones D, Leidy H. Dietary protein and muscle in older persons. Curr Opin Clin Nutr Metab Care 2014; 17: 5-11.
27. Groen BB, Res PT, Pennings B, et al. Intragastric protein administration stimulates overnight muscle protein synthesis in elderly men. Am J Physiol Endocrinol Metab 2012; 302: E52-60.
28. Lustgarten MS, Price LL, Chale A, et al. Branched chain amino acids are associated with muscle mass in functionally limited older adults. J Gerontol A Biol Sci Med Sci 2013; 69: 717-724.
29. Gryson C, Walrand S, Giraudet C, et al. Fast proteins' with a unique essential amino acid content as an optimal nutrition in the elderly: Growing evidence. Clin Nutr 2014; 33: 642-648.
30. Wall BT, Hamer HM, Lange Ade, et al. Leucine co-ingestion improves postprandial muscle protein accretion in elderly men. Clin Nutr 2013; 32: 412-419.
31. Pennings B, Groen B, Lange A de, et al.Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men. Am J Physiol Endocrinol Metab 2012; 302: E992-E999.
32. McCormack WP, Stout JR, Emerson NS, et al. Oral nutritional supplement fortified with beta-alanine improves physical working capacity in older adults: A randomized, placebo-controlled study. Exp Gerontol 2013; 48: 933-939.
33. del Favero S, Roschel H, Solis MY, et al. Beta-alanine (Carnosyn) supplementation in elderly subjects (60-80 years): Effects on muscle carnosine content and physical capacity. Amino Acids 2012; 43: 49-56.
34. Dirks ML, Wall BT, Nilwik R, et al. Skeletal muscle disuse atrophy is not attenuated by dietary protein supplementation in healthy older men. J Nutr 2014; 144: 1196-1203.
35. Deutz NE, Pereira SL, Hays NP, et al. Effect of beta-hydroxy-beta-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults. Clin Nutr 2013; 32: 704-712.
36. Fukagawa NK. Protein and amino acid supplementation in older humans. Amino Acids 2013; 44: 1493-1509.
37. Burd NA, Gorissen SH, van Loon LJ. Anabolic resistance of muscle protein synthesis with aging. Exerc Sport Sci Rev 2013; 41: 169-173.
38. Cermak NM, Res PT, de Groot LC, et al. Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: A meta-analysis. Am J Clin Nutr 2012; 96: 1454-1464.
39. Daly RM, O'Connell SL, Mundell NL, et al. Protein-enriched diet, with the use of lean red meat, combined with progressive resistance training enhances lean tissue mass and muscle strength and reduces circulating IL-6 concentrations in elderly women: A cluster randomized controlled trial. Am J Clin Nutr 2014; 99: 899-910.
40. Leenders M, Verdijk LB, Van der HoevenF L, et al. Protein supplementation during resistance-type exercise training in the elderly. Med Sci Sports Exerc 2013; 45: 542-552.
41. Okazaki K, Yazawa D, Goto M, et al. Effects of macronutrient intake on thigh muscle mass during home-based walking training in middle-aged and older women. Scand J Med Sci Sports 2013; 23: E286-e292.
42. Witard OC, Jackman SR, Breen L, et al. Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise. Am J Clin Nutr 2014; 99: 86-95.
43. Reitelseder S, Agergaard J, Doessing S, et al. Whey and casein labeled with L-[1-13C]leucine and muscle protein synthesis: Effect of resistance exercise and protein ingestion. AJP: Endocrinology and Metabolism 2010; 300: E231-E242. http://ajpendo.physiology.org/content/ajpendo/300/1/E231.full.pdf# zoom=75.
44. Yang Y, Breen L, Burd NA, et al. Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. Br J Nutr 2012; 108: 1780-1788.
45. ChaléA, Cloutier GJ, Hau C, et al. Efficacy of whey protein supplementation on resistance exercise-induced changes in lean mass, muscle strength, and physical function in mobility-limited older adults. J Gerontol A Biol Sci Med Sci 2013; 68: 682-690.
46. Manninen AH. Protein hydrolysates in sports nutrition. Nutr Metab (Lond) 2009; 6: 38.
47. Burd NA, Yang Y, Moore DR, et al. Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. Br J Nutr 2012; 108: 958-962.
48. Shenoy S, Bedi R, Sandhu JS. Effect of soy isolate protein and resistance exercises on muscle performance and bone health of osteopenic/osteoporotic postmenopausal women. J Women Aging 2013; 25: 183-198.
49. Clegg A, Young J, Iliffe S, et al. Frailty in elderly people. Lancet 2013; 381: 752-762.
50. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56: M146-M156.
51. Kobayashi S, Asakura K, Suga H, et al. High protein intake is associated with low prevalence of frailty among old Japanese women: A multicenter crosssectional study. Nutr J 2013; 12: 164.
52. Shikany JM, Barrett-Connor E, Ensrud KE, et al. Macronutrients, diet quality, and frailty in older men. J Gerontol A Biol Sci Med Sci 2014; 69: 695-701.
53. Kim C, Lee K. Preventive effect of protein-energy supplementation on the functional decline of frail older adults with low socioeconomic status: A community-based randomized controlled study. J Gerontol A Biol Sci Med Sci 2013; 68: 309-316.
54. Cesari M. Perspective: Protein supplementation against sarcopenia and frailty: Future perspectives from novel data. J Am Med Dir Assoc 2013; 14: 62-63.
55. Tieland M, van de Rest O, Dirks ML, et al. Protein supplementation improves physical performance in frail elderly people: A randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc 2012; 13: 720-726.
56. Tieland M, Dirks ML, van der Zwaluw N, et al. Protein supplementation increases muscle mass gain during prolonged resistance-type exercise training in frail elderly people: A randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc 2012; 13: 713-719.
57. Drevet S, Bioteau C, Maziere S, et al. Prevalence of protein-energy malnutrition in hospital patients over 75years of age admitted for hip fracture. Orthop Traumatol Surg Res 2014; 100: 669-674.
58. Bell J, Bauer J, Capra S, et al. Barriers to nutritional intake in patients with acute hip fracture: Time to treat malnutrition as a disease and food as a medicine? Can J Physiol Pharmacol 2013; 91: 489-495.
59. Li H, Cheng H, Liang J, et al. Functional recovery of older people with hip fracture: Does malnutrition make a difference? J Adv Nurs 2013; 69: 1691-1703.
60. Myint MW, Wu J, Wong E, et al. Clinical benefits of oral nutritional supplementation for elderly hip fracture patients: A single blind randomised controlled trial. Age Ageing 2013; 42: 39-45.
61. Dreyer HC, Strycker LA, Senesac HA, et al. Essential amino acid supplementation in patients following total knee arthroplasty. J Clin Invest 2013; 123: 4654-4666.