Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): A potential source for functional food ingredients and drug formulations

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Zengin, Gokhan ^a   Uysal, Ahmet ^a   Gunes, Erdogan ^a   Aktumsek, Abdurrahman ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBENZOIC ACID; ALPHA GLUCOSIDASE; AMYLASE; ANTIINFECTIVE AGENT; ANTIOXIDANT; APIGENIN; BENZOIC ACID; BETA CAROTENE; CAFFEIC ACID; CATECHIN; CHLOROGENIC ACID; CINNAMIC ACID; COTONEASTER NUMMULARIA EXTRACT; EPICATECHIN; FERULIC ACID; FLAVONOID; IRON; LINOLEIC ACID; LUTEOLIN; METHANOL; MONOPHENOL MONOOXYGENASE; PARA COUMARIC ACID; PHENOL; PLANT EXTRACT; PROTOCATECHUIC ACID; ROSMARINIC ACID; SYRINGIC ACID; UNCLASSIFIED DRUG; VANILLIN; WATER; ACETIC ACID DERIVATIVE; ACETIC ACID ETHYL ESTER; ANTIMUTAGENIC AGENT; ENZYME; ENZYME INHIBITOR; PHENOL DERIVATIVE; PROTEIN BINDING;

ABTS RADICAL SCAVENGING ASSAY; ANTIBACTERIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASSAY; BACILLUS CEREUS; BACTERIAL STRAIN; BETA CAROTENE LINOLEIC ACID ASSAY; BIOLOGICAL ACTIVITY; COLORIMETRY; CONTROLLED STUDY; COTONEASTER NUMMULARIA; CUPRIC ION REDUCING ASSAY; DPPH RADICAL SCAVENGING ASSAY; DRUG DETERMINATION; DRUG FORMULATION; DRUG IDENTIFICATION; ENTEROCOCCUS FAECALIS; ENZYME ACTIVITY; ESCHERICHIA COLI; FERRIC REDUCING POWER ASSAY; FUNCTIONAL FOOD; KLEBSIELLA PNEUMONIAE; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MUTAGENICITY; NONHUMAN; PHOSPHOMOLYBDENUM ASSAY; PHYTOCHEMISTRY; PSEUDOMONAS AERUGINOSA; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROSACEAE; SALMONELLA ENTERITIDIS; SALMONELLA TYPHIMURIUM; STREPTOCOCCUS PNEUMONIAE; CHEMISTRY; DRUG EFFECTS; GENETICS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOLATION AND PURIFICATION; MEDICINAL CHEMISTRY; METABOLISM; MICROBIAL SENSITIVITY TEST; MUTAGEN TESTING; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM;

COTONEASTER NUMMULARIA;

ACETATES; ANTI-BACTERIAL AGENTS; ANTIMUTAGENIC AGENTS; ANTIOXIDANTS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; ENZYMES; FLAVONOIDS; FUNCTIONAL FOOD; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; METHANOL; MICROBIAL SENSITIVITY TESTS; MUTAGENICITY TESTS; PHENOLS; PLANT EXTRACTS; PROTEIN BINDING; ROSACEAE; SALMONELLA TYPHIMURIUM; WATER;

EID: 84915746974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113527     Document Type: Article

References (61)

1. Leonti M (2012) The co-evolutinary perspective of the food-medicine continuum and wild gathered and cultivated vegetables. Gen. Res. Crop Evol 59: 1295-1302.
2. Suhaj M (2006) Spice antioxidants isolation and their antiradical activity: a review. J. Food Comp. and Anal 19: 531-537.
3. Fang L, Kraus B, Lehmann J, Heilmann J, Zhang Y, et al. (2008) Design and synthesis of tacrine-ferulic acid hybrids as multipotent anti-Alzheimer drug candidates. Bioorg. Med. Chem. Lett 18: 2905-2909.
4. Chakrabarti R, Rajagopalan R (2002) Diabetes and insulin resistance associated disorders: Disease and the therapy. Curr. Sci 83. 1533-1538.
5. Karioti A, Protopappa A, Megoulas N, Skaltsa H (2007) Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum. Bioorg. Med. Chem 15: 2708-2714.
6. Okombi S, Rival D, Bonnet S, Mariotte AM, Perrier E, et al. (2006) Analogues of N-hydroxycinnamoylphenalkylamides as inhibitors of human melanocyte-tyrosinase. Bioorg. Med. Chem. Lett 16(8): 2252-2255.
7. Kinghorn AD, Su BN, Jang DS, Chang LC, Lee D, et al. (2004) Natural inhibitors of carcinogenesis. Planta Med 70: 691-705.
8. Eldeen IMS, Elgorashi EE, Staden JV (2005) Antibacterial, anti-inflammatory, anti-cholinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine. J. Ethnopharmacol 102: 457-464.
9. Khan S, Riaz N, Afza N, Malik A, Rehman A, et al. (2009) Antioxidant constituents from Cotonester racemiflora, J. Asian Nat. Prod. Res 11: 44-48.
10. Davis PH (1972) Flora of Turkey and the East Aegean Islands, Edinburgh, 4.
11. Pala N, Negi A, Todaria N (2010) Traditional uses of medicinal plants of Pauri Garhwal, Uttrakhan. N. Y. Sci. J 8: 57-61.
12. Pandey MR (2007) Use of medicinal plants in Traditional Tibetan theraphy system in upper Mustang Nepal. Our Nat 4: 69-82.
13. Cakilcioglu U, Khatun S, Turkoglu I, Hayta S (2011) Ethnopharmacological survey of medicinal plants in Maden (Elazig-Turkey). J Ethnopharmocol 137: 469-486.
14. Ozgen U, Kaya Y, Houghton P (2012) Folk medicines in the villages of Ilica District (Erzurum-Turkey). Turk. J. Biol 36: 93-106.
15. Polat R, Cakilcioglu U, Satil F (2013) Traditional uses of medicinal plants in Solhan (Bingöl-Turkey). J. Ethnopharmocol 148: 951-963.
16. Caponio F, Alloggio V. Gomes T (1999) Phenolic compounds of virgin olive oil: influence of paste preperation techniques. Food Chem 64: 203-209.
17. Slinkard K, Singleton VL (1977) Total phenol analyses: Automation and comparison with manual methods. Am. J. Enol. Viticult 28: 49-55.
18. Berk S, Tepe B, Arslan S, Sarikurkcu C (2011) Screening of the antioxidant, antimicrobial and DNA damage protection potentials of the aqueous extract of Asplenium ceterach DC. Afr. J. Biotechnol 10: 8902-8908.
19. Sarikurkcu C, Eryigit F, Cengiz M, Tepe B, Cakir A, et al. (2012) Screening of the antioxidant activity of the essential oil and methanol extract of Mentha pulegium L. from Turkey. Spectrosc. Lett 45: 352-358.
20. Sarikurkcu C (2011) Antioxidant activities of solvent extracts from endemic Cyclamen mirabile Hildebr. tubers and leaves. Afr. J. Biotechnol 10: 831-839.
21. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, et al. (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Bio. Med 26: 1231-1237.
22. Dasgupta N, De B (2004) Antioxidant activity of Piper betel L. leaf extract in vitro. Food Chem 88: 219-224.
23. Apak R, Guclu K, Ozyurek M, Karademir SE, Ercag E (2006) The cupric ion reducing antioxidant capacity and polyphenolic content of some herbal teas. Int. J. Food Sci. Nutr 57: 292-304.
24. Oyaizu M (1986) Studies on products of browning reactions: antioxidative activities of browning reaction prepared from glucosamine. Jpn J. Nutr 44: 307-315.
25. Aktumsek A, Zengin G, Guler GO, Cakmak YS, Duran A (2013) Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species. Food Chem. Toxicol 55: 290-296.
26. Erdogan-Orhan I, Baki E, Senol S. Yilmaz G (2010) Sage-called plant species sold in Turkey and their antioxidant activities. J. Serb. Chem. Soc 75: 1491-1501.
27. Zengin G, Sarikurkcu C, Aktumsek A, Ceylan R, Ceylan O (2014) A comprehensive study on phytochemical characterization of Haplophyllum myrtifolium Boiss. endemic to Turkey and its inhibitory potential against key enzymes involved in Alzheimer, skin diseases and type II diabetes. Ind. Crops Prod 53: 244-251.
28. Dean BJ, Brooks TM, Hodson-Walker G, Hutson DH (1985) Genetic toxicology testing of 41 industrial chemicals, Mutat. Res 153: 57-77.
29. Maron DM, Ames BN (1983) Revised methods for the Salmonella mutagenicity test. Mutat Res 113: 173-215.
30. Mortelmans K, Zeiger E (2000) The Ames Salmonella/microsome mutagenicity assay. Mutat. Res. Fund. Mol. M 455(1): 29-60.
31. Rajaei A, Berzegar M, Mobarez AM, Sahari MA, Esfahani ZH (2010) Antioxidant, Anti-Microbial and Antimutagenicity Activities of Pistachio (Pistachia vera) Green Hull Extract. Food Chem Toxicol 48: 107-112.
32. Negi Ps, Jayaprakasha GK, Jena BS (2003) Antioxidant and antimutagenic activities of pomegranate peel extracts. Food Chem 80: 393-397.
33. Koç ZE, Aladag MO, Uysal A (2013) Synthesis of novel dopamine derived multidirectional ligands from cyanuric chloride structural and antimicrobial studies. EXCLIJ 12: 396-403.
34. Manian R, Anusuya N, Siddhuraju P, Manian S (2008) The antioxidant activity and free radical scavenging potential of two different solvent extracts of Camellia sinensis (L.) O. Kuntz, Ficus bengalensis L. and Ficus racemosa L. Food Chem 107: 100-107.
35. Priya Darsini DT, Maheshu V, Vishnupriya M, Nishaa S, Sasikumar JM (2013) Antioxidant potential and amino acid analysis of underutilized tropical fruit Limonia acidissima L. Free Radical and Antioxidants 3: 62-69.
36. Adebiyi AO, Koekemoer T, Adebiyi AP, Smith N, Baxter E, et al. (2009) Antimicrobial and antioxidant activities of crude extracts of two Nigerian chewing sticks. Pharm. Biol 47(4): 320-327.
37. Chandini SK., Ganesan P, Bhaskar N (2008) In vitro antioxidant activities of three selected brown seaweeds of India. Food Chem 107: 707-713.
38. Gallegos-Tintoré S, Torres-Fuentes C, Martínez-Ayala AL, Solorza-Feria J, Alaiz M, et al. (2011) Antioxidant and chelating activity ofJatropha curcas L. protein hydrolysates. J. Sci. Food Agric 91: 1618-1624.
39. Goze I, Alim A, Tepe AS, Sokmen M, Sevgi K, et al. (2009) Screening of the antioxidant activity of essential oil and various extracts of Origanum rotundifolium Boiss. from Turkey. J. Med. Plant Res 3: 246-254.
40. Aksoy L, Kolay E, Agilonu Y, Aslan Z, Kargioglu M (2013) Free radical scavenging activity, total phenolic content, total antioxidant status, and total oxidant status of endemic Thermopsis turcica. Saudi J. Biol. Sci 20: 235-239.
41. Javanmardi J, Stushnoff C, Locke E, Vivanco JM (2003) Antioxidant activity and total phenolic content of Iranian Ocimum accessions. Food Chem 83: 547-550.
42. Skotti E, Anastasaki E, Kanellou G, Polissiou M, Taratilis PA (2014) Total phenolic content, antioxidant activity and toxicity of aqueous extracts from selected Greek medicinal and aromatic plants. Ind. Crops Prod 53: 46-54.
43. Jang HD, Chang KS, Huang YS, Hsu CL, Lee SH, et al. (2007) Principal phenolic phytochemicals and antioxidant activities of three Chinese medicial plants. Food Chem 103: 749-756.
44. Mori T, Koyama N, Guillot-Sestier MV, Tan J, Town T (2013) Ferulic acid is a nutraceutical b-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice. PLoS ONE 8: e55774.
45. Roy S, Metya SK., Sannigrahi S, Rahaman N, Ahmed F (2013) Treatment with ferulic acid to rats with streptozotocin-induced diabetes: effects on oxidative stress, pro-inflammatory cytokines, and apoptosis in the pancreatic b cell. Endocrine 44: 369-379.
46. Saija A, Tomaino A, Trombetta D, De Pasquale A, Uccella N, et al. (2000) In vitro and in vivo evaluation of caffeic and ferulic acids as topical photoprotective agents. Int. J. Pharm 199: 39-47.
47. Borges A, Ferreira C, Saavedra MJ, Simoes M (2013) Antibacterial activity and mode of action of ferulic and gallic acids against pathogenic bacteria. Microb. Drug Resis 19: 256-265.
48. Ou S, Kwok KC (2004) Ferulic acid: pharmaceutical functions, preparation and applications in foods. J. Sci Food Agr 84: 1261-1269
49. Oksana S, Marian B, Mahendra R, Bo SH (2012) Plant phenolic compounds for food, pharmaceuticaland cosmetics production. J. Med. Plant Res 6: 2526-2539.
50. Shahwar D, Rahman S, Raza MA (2010) Acetyl cholinesterase inhibition potential and antioxidant activities of ferulic acid isolated from Impatiens bicolor Linn. J. Med. Plants Res 4: 260-266.
51. Vladimir-Knežević S, Blažeković B, Kindl M, Vladić J, Lower-Nedza AD, et al. (2014) Acetylcholinesterase Inhibitory, Antioxidant and phytochemical properties of selected medicinal plants of the Lamiaceae family. Molecules 19: 767-782.
52. Higdon JV, Frei B (2003) Tea catechins and polyphenols: Health effects, metabolism, and antioxidant functions. Crit. Rev. Food Sci 43: 89-143.
53. Mamiya T, Kise M, Morikawa K (2008) Ferulic acid attenuated cognitive deficits and increase in carbonyl proteins induced by buthionine-sulfoximine in mice. Neurosci. Lett 430: 115-118.
54. Dalar A, Konczak I (2013) Phenolic contents, antioxidant capacities and inhibitory activities against key metabolic syndrome relevant enzymes of herbal teas from Eastern Anatolia. Ind. Crop Prod 44: 383-390.
55. Ranilla LG, Kwon YI, Apostolidis E, Shetty K (2010) Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresou. Technol 101: 4676-4689.
56. Edenharder R, Van Petersdorf I, Rauscher V (1993) Antimutagenic effects of flavonoids, chalcones and structurally related compounds on the activity of 2-amino-3-methylimidazol (4, 5-f) quinoline (IQ) and other heterocyclic amine mutagens from cooked food. Mutat. Res 287: 261-274.
57. Buening MK, Chang RL, Huang MT, Fortner JG, Wood AW, et al. (1981) Activation and inhibition of benzo(a) pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occuring flavonoids. Cancer Res 41: 67-72.
58. Kappus H (1986) Overview of enzyme systems involved in bioreduction of drugs and in redox cycling, Biochem. Pharmacol 35: 1-6.
59. Parke DV, Ioannides C, Lewis DF (1991) The 1990 Pharmaceutical Manufacturers Association of Canada keynote lecture. The role of the cytochromes P450 in the detoxication and activation of drugs and other chemicals. Can. J. Physiol. Pharmacol 69: 537-549.
60. Mitscher AL, Telikepalli H, Mcghee E, Shankel DM (1996) Natural antimutagenic agents. Mutat. Res 350: 143-152.
61. Horn RC, Vargas VMF (2003) Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay, Mutagenesis 18: 113-118.