PARP1-mediated necrosis is dependent on parallel JNK and Ca2+/calpain pathways

Journal of Cell Science

Volumn 127, Issue 19, 2014, Pages 4134-4145

  Douglas, Diana L ^a   Baines, Christopher P ^a,b,c  

^a UNIVERSITY OF MISSOURI   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c University of Missouri   (United States)

Author keywords

AIF; Calpain; Cell death; JNK; Mitochondria; Necrosis; PARP1

Indexed keywords

APOPTOSIS INDUCING FACTOR; BETA LAPACHONE; CALCIUM ION; CALPAIN; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN; PROTEIN BAX; RECEPTOR INTERACTING PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROBLAST; IMMUNOFLUORESCENCE; IN VITRO STUDY; MITOCHONDRIAL PERMEABILITY; MOUSE; NECROSIS; NONHUMAN; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; 3T3 CELL LINE; ANIMAL; APOPTOSIS; CELL CULTURE TECHNIQUE; CELL DEATH; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

3T3 CELLS; ANIMALS; APOPTOSIS; CALPAIN; CELL CULTURE TECHNIQUES; CELL DEATH; MAP KINASE SIGNALING SYSTEM; MICE; MITOCHONDRIA; NECROSIS; POLY(ADP-RIBOSE) POLYMERASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84913616801     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.128009     Document Type: Article

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