μ-calpain activation in β-lapachone-mediated apoptosis

Cancer Biology and Therapy

Volumn 2, Issue 2, 2003, Pages 141-152

  Tagliarino, Colleen ^a   Pink, John J ^a   Reinicke, Kathryn E ^a   Simmers, Sara M ^a   Wuerzberger Davis, Shelly M ^a   Boothman, David A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

lapachone; Apoptosis; Breast cancer; Ca2+; Calpain

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; BETA LAPACHONE; BETA-LAPACHONE; CALCIUM; CALCIUM BINDING PROTEIN; CALPAIN; CALPASTATIN; CASPASE; CYSTEINE PROTEINASE INHIBITOR; M CALPAIN; M-CALPAIN; MU CALPAIN; MU-CALPAIN; NAPHTHOQUINONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NQO1 PROTEIN, HUMAN; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

APOPTOSIS; ARTICLE; BREAST TUMOR; CELL CULTURE; CELL NUCLEUS; CLONOGENIC ASSAY; CONFOCAL MICROSCOPY; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; FEMALE; GENETICS; HUMAN; METABOLISM; NICK END LABELING; PATHOLOGY; PROTEIN TRANSPORT; WESTERN BLOTTING;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CALCIUM; CALCIUM-BINDING PROTEINS; CALPAIN; CASPASES; CELL NUCLEUS; COLONY-FORMING UNITS ASSAY; CYSTEINE PROTEINASE INHIBITORS; CYTOSOL; ENZYME ACTIVATION; FEMALE; HUMANS; IN SITU NICK-END LABELING; MICROSCOPY, CONFOCAL; NAD(P)H DEHYDROGENASE (QUINONE); NAPHTHOQUINONES; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0141976410     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.2.2.237     Document Type: Article

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