Inhibition of poly(ADP-ribose) polymerase activation attenuates β-lapachone-induced necrotic cell death in human osteosarcoma cells

Toxicology and Applied Pharmacology

Volumn 182, Issue 2, 2002, Pages 116-125

  Liu, Tcho Jen ^a   Lin, Sheng Yi ^a   Chau, Yat Pang ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

ATP; NAD; Necrosis; PARP; lapachone

Indexed keywords

3 AMINOBENZAMIDE; ADENOSINE TRIPHOSPHATE; BETA LAPACHONE; CASPASE; CYCLOSPORIN A; CYTOCHROME C; ENZYME INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADP RIBOSE)POLYMERASE INHIBITOR; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CONTROLLED STUDY; DEPLETION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NECROSIS; OSTEOSARCOMA; OXIDATIVE STRESS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 0036353076     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2002.9438     Document Type: Article

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