Insights into the role of Asp792.50 in β2 adrenergic receptor activation from molecular dynamics simulations

Biochemistry

Volumn 53, Issue 46, 2014, Pages 7283-7296

  Ranganathan, Anirudh ^a,b   Dror, Ron O ^c   Carlsson, Jens ^a,b  

^a SCIENCE FOR LIFE LABORATORY   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CRYSTAL ATOMIC STRUCTURE; FREE ENERGY; MOLECULAR DYNAMICS; PROTONATION;

ADRENERGIC RECEPTORS; FREE-ENERGY CALCULATIONS; G-PROTEIN COUPLED RECEPTORS; HIGH RESOLUTION CRYSTAL STRUCTURE; MOLECULAR DYNAMICS SIMULATIONS; PROTONATION STATE; RECEPTOR SIGNALING; STRUCTURAL BIOLOGY;

ACTIVATION ANALYSIS;

ASPARTIC ACID; BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; SODIUM CHLORIDE; PROTON;

ALGORITHM; ARTICLE; CALCULATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; IONIZATION; LIPID BILAYER; MOLECULAR DYNAMICS; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTON TRANSPORT; SIMULATION; STATIC ELECTRICITY; ANIMAL; CHEMISTRY; ENZYME ACTIVE SITE; METABOLISM; PROTEIN CONFORMATION; PROTEIN DATABASE; THERMODYNAMICS;

ANIMALS; CATALYTIC DOMAIN; DATABASES, PROTEIN; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTONS; RECEPTORS, ADRENERGIC, BETA-2; THERMODYNAMICS;

EID: 84913603703     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi5008723     Document Type: Article

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