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Volumn 312, Issue , 2014, Pages 79-100

Recent advances in molecular and cell biology of testicular germ-cell tumors

Author keywords

Aurora B; GPR30; HMGA; PATZ1; Seminomas; Testicular germ cell tumors

Indexed keywords

ALPHA FETOPROTEIN; ANGIOGENESIS INHIBITOR; AURORA B KINASE; AURORA KINASE INHIBITOR; BARASERTIB; CHORIONIC GONADOTROPIN; ESTROGEN; ESTROGEN RECEPTOR BETA; G PROTEIN COUPLED RECEPTOR 30; GSK 1070916; HESPERADIN; HIGH MOBILITY GROUP A1A PROTEIN; HIGH MOBILITY GROUP A2 PROTEIN; IMATINIB; MESSENGER RNA; MICRORNA; N [4 [6 METHOXY 7 (3 MORPHOLINOPROPOXY) 4 QUINAZOLINYLAMINO]PHENYL]BENZAMIDE; NEK2 PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER 3; PROTEIN TYROSINE KINASE INHIBITOR; TOZASERTIB; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; TUMOR MARKER; UNCLASSIFIED DRUG; VANDETANIB; TUMOR PROTEIN;

EID: 84913592754     PISSN: 19376448     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800178-3.00003-8     Document Type: Chapter
Times cited : (17)

References (88)
  • 1
    • 3142779194 scopus 로고    scopus 로고
    • Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling
    • Almstrup K., Hoei-Hansen C.E., Wirkner U., Blake J., Schwager C., Ansorge W., et al. Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling. Cancer Res. 2004, 64:4736-4743.
    • (2004) Cancer Res. , vol.64 , pp. 4736-4743
    • Almstrup, K.1    Hoei-Hansen, C.E.2    Wirkner, U.3    Blake, J.4    Schwager, C.5    Ansorge, W.6
  • 2
    • 58049200457 scopus 로고    scopus 로고
    • OCT4 spliced variants are differentially expressed in human pluripotent and non-pluripotent cells
    • Atlasi Y., Mowla S.J., Ziaee S.A., Gokhale P.J., Andrews P.W. OCT4 spliced variants are differentially expressed in human pluripotent and non-pluripotent cells. Stem Cells 2008, 26:3068-3074.
    • (2008) Stem Cells , vol.26 , pp. 3068-3074
    • Atlasi, Y.1    Mowla, S.J.2    Ziaee, S.A.3    Gokhale, P.J.4    Andrews, P.W.5
  • 4
    • 60549086412 scopus 로고    scopus 로고
    • Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas
    • Barbagallo F., Paronetto M.P., Franco R., Chieffi P., Dolci S., Fry A.M., et al. Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas. J. Pathol. 2009, 217:431-441.
    • (2009) J. Pathol. , vol.217 , pp. 431-441
    • Barbagallo, F.1    Paronetto, M.P.2    Franco, R.3    Chieffi, P.4    Dolci, S.5    Fry, A.M.6
  • 6
    • 0020415302 scopus 로고
    • Screening for carcinoma in situ of the contralateral testis in patients with germinal testicular cancer
    • Berthelsen J.G., Skakkebaek N.E., von der Maase H., Sorensen B.L., Mogensen P. Screening for carcinoma in situ of the contralateral testis in patients with germinal testicular cancer. Br. Med. J. 1982, 285:1683-1686.
    • (1982) Br. Med. J. , vol.285 , pp. 1683-1686
    • Berthelsen, J.G.1    Skakkebaek, N.E.2    von der Maase, H.3    Sorensen, B.L.4    Mogensen, P.5
  • 7
    • 0036949568 scopus 로고    scopus 로고
    • Dietary factors and the risk of testicular cancer
    • Bonner M.R., McCann S.E., Moysich K.B. Dietary factors and the risk of testicular cancer. Nutr. Cancer 2002, 44:35-43.
    • (2002) Nutr. Cancer , vol.44 , pp. 35-43
    • Bonner, M.R.1    McCann, S.E.2    Moysich, K.B.3
  • 8
    • 79954589258 scopus 로고    scopus 로고
    • RNA-binding protein LIN28 is a marker for testicular germ cell tumors
    • Cao D., Allan R.W., Cheng L., Peng Y., Guo C.C., Dahiya N., et al. RNA-binding protein LIN28 is a marker for testicular germ cell tumors. Hum. Pathol. 2011, 42:710-718.
    • (2011) Hum. Pathol. , vol.42 , pp. 710-718
    • Cao, D.1    Allan, R.W.2    Cheng, L.3    Peng, Y.4    Guo, C.C.5    Dahiya, N.6
  • 10
    • 0034653701 scopus 로고    scopus 로고
    • Genetics and biology of adult human male germ cell tumors
    • Chaganti R.S., Houldsworth J. Genetics and biology of adult human male germ cell tumors. Cancer Res. 2000, 60:1474-1482.
    • (2000) Cancer Res. , vol.60 , pp. 1474-1482
    • Chaganti, R.S.1    Houldsworth, J.2
  • 11
    • 81055132877 scopus 로고    scopus 로고
    • Chromosome X-encoded cancer/testis antigens show distinctive expression patterns in developing gonads and in testicular seminoma
    • Chen Y.T., Chiu R., Lee P., Beneck D., Jin B., Old L.J. Chromosome X-encoded cancer/testis antigens show distinctive expression patterns in developing gonads and in testicular seminoma. Hum. Reprod. 2011, 26:3232-3243.
    • (2011) Hum. Reprod. , vol.26 , pp. 3232-3243
    • Chen, Y.T.1    Chiu, R.2    Lee, P.3    Beneck, D.4    Jin, B.5    Old, L.J.6
  • 12
    • 84879055302 scopus 로고    scopus 로고
    • Chromosome X-encoded cancer/testis antigens are less frequently expressed in non-seminomatous germ cell tumors than in seminomas
    • Chen Y.T., Cao D., Chiu R., Lee P. Chromosome X-encoded cancer/testis antigens are less frequently expressed in non-seminomatous germ cell tumors than in seminomas. Cancer Immun. 2013, 13:1-10.
    • (2013) Cancer Immun. , vol.13 , pp. 1-10
    • Chen, Y.T.1    Cao, D.2    Chiu, R.3    Lee, P.4
  • 13
    • 34547107302 scopus 로고    scopus 로고
    • Molecular targets for the treatment of testicular germ cell tumors
    • Chieffi P. Molecular targets for the treatment of testicular germ cell tumors. Mini Rev. Med. Chem. 2007, 7:755-759.
    • (2007) Mini Rev. Med. Chem. , vol.7 , pp. 755-759
    • Chieffi, P.1
  • 14
    • 84876700792 scopus 로고    scopus 로고
    • Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumours: an overview
    • Chieffi P., Chieffi S. Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumours: an overview. J. Cell. Physiol. 2013, 228:1641-1646.
    • (2013) J. Cell. Physiol. , vol.228 , pp. 1641-1646
    • Chieffi, P.1    Chieffi, S.2
  • 15
    • 84894781888 scopus 로고    scopus 로고
    • An up-date on the molecular biomarkers as potential therapeutic targets in human testicular germ cell tumours
    • Chieffi P., Chieffi S. An up-date on the molecular biomarkers as potential therapeutic targets in human testicular germ cell tumours. Open Androl. J. 2013, 5:6-9.
    • (2013) Open Androl. J. , vol.5 , pp. 6-9
    • Chieffi, P.1    Chieffi, S.2
  • 16
    • 84904096331 scopus 로고    scopus 로고
    • An up-date on newly discovered immunohistochemical biomarkers for the diagnosis of human testicular germ cell tumors
    • Chieffi P., Chieffi S. An up-date on newly discovered immunohistochemical biomarkers for the diagnosis of human testicular germ cell tumors. Histol. Histopathol 2014, 29:999-1006.
    • (2014) Histol. Histopathol , vol.29 , pp. 999-1006
    • Chieffi, P.1    Chieffi, S.2
  • 17
    • 0033786883 scopus 로고    scopus 로고
    • Estradiol-induced mitogen-activated protein kinase (extracellular signal-regulated kinase 1 and 2) activity in the frog (Rana esculenta) testis
    • Chieffi P., Colucci D'Amato G.L., Staibano S., Franco R., Tramontano D. Estradiol-induced mitogen-activated protein kinase (extracellular signal-regulated kinase 1 and 2) activity in the frog (Rana esculenta) testis. J. Endocrinol. 2000, 167:77-84.
    • (2000) J. Endocrinol. , vol.167 , pp. 77-84
    • Chieffi, P.1    Colucci D'Amato, G.L.2    Staibano, S.3    Franco, R.4    Tramontano, D.5
  • 19
    • 0036137838 scopus 로고    scopus 로고
    • 17β-estradiol induces spermatogonial proliferation through mitogen-activated protein kinase (extracellular signal-regulated kinase 1) activity In the lizard (Podarcis s. sicula)
    • Chieffi P., Colucci-D'Amato G.L., Guarino F., Salvatore G., Angelini F. 17β-estradiol induces spermatogonial proliferation through mitogen-activated protein kinase (extracellular signal-regulated kinase 1) activity In the lizard (Podarcis s. sicula). Mol. Reprod. Dev. 2002, 61:218-225.
    • (2002) Mol. Reprod. Dev. , vol.61 , pp. 218-225
    • Chieffi, P.1    Colucci-D'Amato, G.L.2    Guarino, F.3    Salvatore, G.4    Angelini, F.5
  • 21
    • 73349136302 scopus 로고    scopus 로고
    • Molecular and cell biology of testicular germ cell tumors
    • Chieffi P., Franco R., Portella G. Molecular and cell biology of testicular germ cell tumors. Int. Rev. Cell Mol. Biol. 2009, 278:277-308.
    • (2009) Int. Rev. Cell Mol. Biol. , vol.278 , pp. 277-308
    • Chieffi, P.1    Franco, R.2    Portella, G.3
  • 22
    • 84871903216 scopus 로고    scopus 로고
    • Recent advances in the biology of germ cell tumors: implications for the diagnosis and treatment
    • Chieffi P., Chieffi S., Franco R., Sinisi A. Recent advances in the biology of germ cell tumors: implications for the diagnosis and treatment. J. Endocrinol. Invest. 2012, 35:1015-1020.
    • (2012) J. Endocrinol. Invest. , vol.35 , pp. 1015-1020
    • Chieffi, P.1    Chieffi, S.2    Franco, R.3    Sinisi, A.4
  • 23
    • 34047169674 scopus 로고    scopus 로고
    • Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future
    • de Jong J., Looijenga L.H. Stem cell marker OCT3/4 in tumor biology and germ cell tumor diagnostics: history and future. Crit. Rev. Oncog. 2006, 12:171-203.
    • (2006) Crit. Rev. Oncog. , vol.12 , pp. 171-203
    • de Jong, J.1    Looijenga, L.H.2
  • 24
    • 42949173880 scopus 로고    scopus 로고
    • Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications
    • de Jong J., Stoop H., Gillis A.J., van Gurp R.J., van de Geijn G.J., Boer M., et al. Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications. J. Pathol. 2008, 215:21-30.
    • (2008) J. Pathol. , vol.215 , pp. 21-30
    • de Jong, J.1    Stoop, H.2    Gillis, A.J.3    van Gurp, R.J.4    van de Geijn, G.J.5    Boer, M.6
  • 25
    • 1542283801 scopus 로고    scopus 로고
    • Phosphorylation of high mobility group protein A2 by Nek kinase during the first meiotic division in mouse spermatocytes
    • Di Agostino S., Fedele M., Chieffi P., Fusco A., Rossi P., Geremia R., et al. Phosphorylation of high mobility group protein A2 by Nek kinase during the first meiotic division in mouse spermatocytes. Mol. Biol. Cell 2004, 15:1224-1232.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1224-1232
    • Di Agostino, S.1    Fedele, M.2    Chieffi, P.3    Fusco, A.4    Rossi, P.5    Geremia, R.6
  • 26
    • 0036901229 scopus 로고    scopus 로고
    • Is risk of testicular cancer related to body size?
    • Dieckmann K.P., Pichlmeier U. Is risk of testicular cancer related to body size?. Eur. Urol. 2002, 42:564-569.
    • (2002) Eur. Urol. , vol.42 , pp. 564-569
    • Dieckmann, K.P.1    Pichlmeier, U.2
  • 27
    • 0035698447 scopus 로고    scopus 로고
    • How valid is the prenatal estrogen excess hypothesis of testicular germ cell cancer? A case control study on hormone-related factors
    • Dieckmann K.P., Endsin G., Pichlmeier U. How valid is the prenatal estrogen excess hypothesis of testicular germ cell cancer? A case control study on hormone-related factors. Eur. Urol. 2001, 40:677-683.
    • (2001) Eur. Urol. , vol.40 , pp. 677-683
    • Dieckmann, K.P.1    Endsin, G.2    Pichlmeier, U.3
  • 29
    • 20144386807 scopus 로고    scopus 로고
    • Loss of tumour suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors
    • Di Vizio D., Cito L., Boccia A., Chieffi P., Insabato L., Pettinato G., et al. Loss of tumour suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors. Oncogene 2005, 24:1882-1894.
    • (2005) Oncogene , vol.24 , pp. 1882-1894
    • Di Vizio, D.1    Cito, L.2    Boccia, A.3    Chieffi, P.4    Insabato, L.5    Pettinato, G.6
  • 31
    • 79953798790 scopus 로고    scopus 로고
    • Down-regulation of estrogen receptor-β associates with transcriptional coregulator PATZ1 delocalization in human testicular seminomas
    • Esposito F., Boscia F., Franco R., Tornincasa M., Fusco A., Kitazawa S., et al. Down-regulation of estrogen receptor-β associates with transcriptional coregulator PATZ1 delocalization in human testicular seminomas. J. Pathol. 2011, 224:110-120.
    • (2011) J. Pathol. , vol.224 , pp. 110-120
    • Esposito, F.1    Boscia, F.2    Franco, R.3    Tornincasa, M.4    Fusco, A.5    Kitazawa, S.6
  • 32
    • 84865420077 scopus 로고    scopus 로고
    • The high mobility group A1-oestrogen receptor β nuclear interaction is impaired in human testicular seminomas
    • Esposito F., Boscia F., Gigantino V., Tornincasa M., Fusco A., Franco R., et al. The high mobility group A1-oestrogen receptor β nuclear interaction is impaired in human testicular seminomas. J. Cell. Physiol. 2012, 227:3749-3755.
    • (2012) J. Cell. Physiol. , vol.227 , pp. 3749-3755
    • Esposito, F.1    Boscia, F.2    Gigantino, V.3    Tornincasa, M.4    Fusco, A.5    Franco, R.6
  • 34
    • 84866175396 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor promotes invasive behaviour in testicular seminoma cells
    • Ferranti F., Muciaccia B., Ricci G., Dovere L., Canipari R., Magliocca F., et al. Glial cell line-derived neurotrophic factor promotes invasive behaviour in testicular seminoma cells. Int. J. Androl. 2012, 35:758-768.
    • (2012) Int. J. Androl. , vol.35 , pp. 758-768
    • Ferranti, F.1    Muciaccia, B.2    Ricci, G.3    Dovere, L.4    Canipari, R.5    Magliocca, F.6
  • 35
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: basic science and clinical progress
    • Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr. Rev. 2004, 25:581-611.
    • (2004) Endocr. Rev. , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 36
    • 0030500450 scopus 로고    scopus 로고
    • New perspectives in clinical oncology from angiogenesis research
    • Folkman J. New perspectives in clinical oncology from angiogenesis research. Eur. J. Cancer 1996, 32:2534-2539.
    • (1996) Eur. J. Cancer , vol.32 , pp. 2534-2539
    • Folkman, J.1
  • 37
    • 0026585997 scopus 로고
    • Familial testicular cancer: a report of the UK family register, estimation of risk and an HLA class 1 sib-pair analysis
    • Forman D., Oliver R.T., Brett A.R., Marsh S.G., Moses J.H., Bodmer J.G., et al. Familial testicular cancer: a report of the UK family register, estimation of risk and an HLA class 1 sib-pair analysis. Br. J. Cancer 1992, 65:255-262.
    • (1992) Br. J. Cancer , vol.65 , pp. 255-262
    • Forman, D.1    Oliver, R.T.2    Brett, A.R.3    Marsh, S.G.4    Moses, J.H.5    Bodmer, J.G.6
  • 38
    • 38049086953 scopus 로고    scopus 로고
    • Detection of high mobility group proteins A1 and A2 represents a valid diagnostic marker in post-puberal testicular germ cell tumours
    • Franco R., Esposito F., Fedele M., Liguori G., Pierantoni G., Botti G., et al. Detection of high mobility group proteins A1 and A2 represents a valid diagnostic marker in post-puberal testicular germ cell tumours. J. Pathol. 2008, 214:58-64.
    • (2008) J. Pathol. , vol.214 , pp. 58-64
    • Franco, R.1    Esposito, F.2    Fedele, M.3    Liguori, G.4    Pierantoni, G.5    Botti, G.6
  • 42
    • 2342639645 scopus 로고    scopus 로고
    • VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
    • Harrington E.A., Bebbington D., Moore J., Rasmussen R.K., Ajose-Adeogun A.O., Nakayama T., et al. VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo. Nat. Med. 2004, 10:262-267.
    • (2004) Nat. Med. , vol.10 , pp. 262-267
    • Harrington, E.A.1    Bebbington, D.2    Moore, J.3    Rasmussen, R.K.4    Ajose-Adeogun, A.O.5    Nakayama, T.6
  • 43
    • 27644448817 scopus 로고    scopus 로고
    • The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
    • Hart A.H., Hartley L., Parker K., Ibrahim M., Looijenga L.H., Pauchnik M., et al. The pluripotency homeobox gene NANOG is expressed in human germ cell tumors. Cancer 2005, 104:2092-2098.
    • (2005) Cancer , vol.104 , pp. 2092-2098
    • Hart, A.H.1    Hartley, L.2    Parker, K.3    Ibrahim, M.4    Looijenga, L.H.5    Pauchnik, M.6
  • 44
    • 0038746733 scopus 로고    scopus 로고
    • The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore microtubule attachment and in maintaining the spindle assembly checkpoint
    • Hauf S., Cole R.W., LaTerra S., Zimmer C., Schnapp G., Walter L., et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore microtubule attachment and in maintaining the spindle assembly checkpoint. J. Cell Biol. 2003, 161:281-294.
    • (2003) J. Cell Biol. , vol.161 , pp. 281-294
    • Hauf, S.1    Cole, R.W.2    LaTerra, S.3    Zimmer, C.4    Schnapp, G.5    Walter, L.6
  • 45
    • 0037087531 scopus 로고    scopus 로고
    • Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies
    • Heinrich M.C., Blanke C.D., Druker B.J., Corless C.L. Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies. J. Clin. Oncol. 2002, 20:1692-1703.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1692-1703
    • Heinrich, M.C.1    Blanke, C.D.2    Druker, B.J.3    Corless, C.L.4
  • 46
    • 22144446409 scopus 로고    scopus 로고
    • Stem cell pluripotency factor NANOG is expressed inhuman fetal gonocytes, testicular carcinoma in situ and germ cell tumours
    • Hoei-Hansen C.E., Almstrup K., Nielsen J.E., Brask Sonne S., Graem N., Skakkebaek N.E., et al. Stem cell pluripotency factor NANOG is expressed inhuman fetal gonocytes, testicular carcinoma in situ and germ cell tumours. Histopathology 2005, 47:48-56.
    • (2005) Histopathology , vol.47 , pp. 48-56
    • Hoei-Hansen, C.E.1    Almstrup, K.2    Nielsen, J.E.3    Brask Sonne, S.4    Graem, N.5    Skakkebaek, N.E.6
  • 47
    • 0347503602 scopus 로고    scopus 로고
    • Part II: testicular cancer-management of advanced disease
    • Jones R.H., Vasey P.A. Part II: testicular cancer-management of advanced disease. Lancet Oncol. 2003, 4:738-747.
    • (2003) Lancet Oncol. , vol.4 , pp. 738-747
    • Jones, R.H.1    Vasey, P.A.2
  • 49
    • 10344236486 scopus 로고    scopus 로고
    • Aurora-kinase inhibitors as anticancer agents
    • Keen N., Taylor S. Aurora-kinase inhibitors as anticancer agents. Nat. Rev. Cancer 2004, 4:927-936.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 927-936
    • Keen, N.1    Taylor, S.2
  • 51
    • 34547668398 scopus 로고    scopus 로고
    • Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells
    • Kim I., Saunders T.L., Morrison S.J. Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 2007, 130:470-483.
    • (2007) Cell , vol.130 , pp. 470-483
    • Kim, I.1    Saunders, T.L.2    Morrison, S.J.3
  • 52
    • 22044442973 scopus 로고    scopus 로고
    • Tyrosine kinases as targets for cancer therapy
    • Krause D.S., Van Etten R.A. Tyrosine kinases as targets for cancer therapy. N. Engl. J. Med. 2005, 353:172-187.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 172-187
    • Krause, D.S.1    Van Etten, R.A.2
  • 53
    • 35748943852 scopus 로고    scopus 로고
    • Doubts raised over stem-cell marker
    • Ledford H. Doubts raised over stem-cell marker. Nature 2007, 449:647.
    • (2007) Nature , vol.449 , pp. 647
    • Ledford, H.1
  • 54
    • 32044467693 scopus 로고    scopus 로고
    • Phase II data with ZD6474, a small-molecule kinase inhibitor of epidermal growth factor receptor and vascular endothelial growth factor receptor, in previously treated advanced non-small-cell lung cancer
    • Lee D. Phase II data with ZD6474, a small-molecule kinase inhibitor of epidermal growth factor receptor and vascular endothelial growth factor receptor, in previously treated advanced non-small-cell lung cancer. Clin. Lung Cancer 2005, 7:89-91.
    • (2005) Clin. Lung Cancer , vol.7 , pp. 89-91
    • Lee, D.1
  • 56
    • 10744221713 scopus 로고    scopus 로고
    • Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors
    • Looijenga L.H., de Leeuw H., van Oorschot M., van Gurp R.J., Stoop H., Gillis A.J., et al. Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors. Cancer Res. 2003, 63:7674-7678.
    • (2003) Cancer Res. , vol.63 , pp. 7674-7678
    • Looijenga, L.H.1    de Leeuw, H.2    van Oorschot, M.3    van Gurp, R.J.4    Stoop, H.5    Gillis, A.J.6
  • 57
    • 0030975886 scopus 로고    scopus 로고
    • Stem cell factor and c-kit in the mammalian testis: lessons originating from Mother Nature's gene knockouts
    • Loveland K.L., Schlatt S. Stem cell factor and c-kit in the mammalian testis: lessons originating from Mother Nature's gene knockouts. J. Endocrinol. 1997, 153:337-344.
    • (1997) J. Endocrinol. , vol.153 , pp. 337-344
    • Loveland, K.L.1    Schlatt, S.2
  • 60
    • 0025611985 scopus 로고
    • Gonadal expression of c-kit encoded at the W locus of the mouse
    • Manova K., Nocka K., Besmer P., Bachvarova R.F. Gonadal expression of c-kit encoded at the W locus of the mouse. Development 1990, 110:1057-1069.
    • (1990) Development , vol.110 , pp. 1057-1069
    • Manova, K.1    Nocka, K.2    Besmer, P.3    Bachvarova, R.F.4
  • 62
    • 0016852799 scopus 로고
    • A study of the primordial germ cells during their migratory phase in Steel mutant mice
    • McCoshen J.A., McCallion D.J. A study of the primordial germ cells during their migratory phase in Steel mutant mice. Experientia 1975, 31:589-590.
    • (1975) Experientia , vol.31 , pp. 589-590
    • McCoshen, J.A.1    McCallion, D.J.2
  • 64
    • 0035870270 scopus 로고    scopus 로고
    • Promotion of seminomatous tumors by targeted overexpression of glial cell line-derived neurotrophic factor in mouse testis
    • Meng X., de Rooij D.G., Westerdahl K., Saarma M., Sariola H. Promotion of seminomatous tumors by targeted overexpression of glial cell line-derived neurotrophic factor in mouse testis. Cancer Res. 2001, 61:3267-3271.
    • (2001) Cancer Res. , vol.61 , pp. 3267-3271
    • Meng, X.1    de Rooij, D.G.2    Westerdahl, K.3    Saarma, M.4    Sariola, H.5
  • 65
    • 0021206780 scopus 로고
    • Cryptorchidism and testis cancer. A typical infantile germ cells followed by carcinoma in situ and invasive carcinoma in adulthood
    • Muller J., Skakkebaek N.E., Nielsen O.H., Graem N. Cryptorchidism and testis cancer. A typical infantile germ cells followed by carcinoma in situ and invasive carcinoma in adulthood. Cancer 1984, 54:629-634.
    • (1984) Cancer , vol.54 , pp. 629-634
    • Muller, J.1    Skakkebaek, N.E.2    Nielsen, O.H.3    Graem, N.4
  • 67
    • 0016381309 scopus 로고
    • The fine structure of possible carcinoma in-situ in the seminiferous tubules in the testis of four infertile men
    • Nielsen H., Nielsen M., Skakkebaek N.E. The fine structure of possible carcinoma in-situ in the seminiferous tubules in the testis of four infertile men. Acta Pathol. Microbiol. Scand. A 1974, 82:235-248.
    • (1974) Acta Pathol. Microbiol. Scand. A , vol.82 , pp. 235-248
    • Nielsen, H.1    Nielsen, M.2    Skakkebaek, N.E.3
  • 68
    • 14644396631 scopus 로고    scopus 로고
    • Testicular germ-cell tumors in a broader perspective
    • Oosterhuis J.W., Looijenga L.H. Testicular germ-cell tumors in a broader perspective. Nat. Rev. Cancer 2005, 5:210-222.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 210-222
    • Oosterhuis, J.W.1    Looijenga, L.H.2
  • 69
    • 0037105758 scopus 로고    scopus 로고
    • Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability
    • Ota T., Suto S., Katayama H., Han Z.B., Suzuki F., Maeda M., et al. Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability. Cancer Res. 2002, 62:5168-5177.
    • (2002) Cancer Res. , vol.62 , pp. 5168-5177
    • Ota, T.1    Suto, S.2    Katayama, H.3    Han, Z.B.4    Suzuki, F.5    Maeda, M.6
  • 70
    • 0036207724 scopus 로고    scopus 로고
    • Expression of the PDGF alpha-receptor 1.5kb transcript, OCT-4, and c-KIT in human normal and malignant tissues Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms
    • Palumbo C., van Roozendaal K., Gillis A.J., van Gurp R.H., de Munnik H., Oosterhuis J.W., et al. Expression of the PDGF alpha-receptor 1.5kb transcript, OCT-4, and c-KIT in human normal and malignant tissues Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms. J. Pathol. 2002, 196:467-477.
    • (2002) J. Pathol. , vol.196 , pp. 467-477
    • Palumbo, C.1    van Roozendaal, K.2    Gillis, A.J.3    van Gurp, R.H.4    de Munnik, H.5    Oosterhuis, J.W.6
  • 71
    • 0034790175 scopus 로고    scopus 로고
    • RNF4 is a growth inhibitor expressed in germ cells and lost in human testicular tumours
    • Pero R., Lembo F., Di Vizio D., Boccia A., Chieffi P., Fedele M., et al. RNF4 is a growth inhibitor expressed in germ cells and lost in human testicular tumours. Am. J. Pathol. 2001, 159:1225-1230.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1225-1230
    • Pero, R.1    Lembo, F.2    Di Vizio, D.3    Boccia, A.4    Chieffi, P.5    Fedele, M.6
  • 73
    • 79851500882 scopus 로고    scopus 로고
    • Aurora B: a new prognostic marker and therapeutic target in cancer
    • Portella G., Passaro C., Chieffi P. Aurora B: a new prognostic marker and therapeutic target in cancer. Curr. Med. Chem. 2011, 18:482-496.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 482-496
    • Portella, G.1    Passaro, C.2    Chieffi, P.3
  • 74
    • 79960853471 scopus 로고    scopus 로고
    • Pathogenesis of testicular carcinoma in situ and germ cell cancer: still more questions than answers
    • Rajpert-De Meyts E., Skakkebaek N.E. Pathogenesis of testicular carcinoma in situ and germ cell cancer: still more questions than answers. Int. J. Androl. 2011, 34:e2-e6.
    • (2011) Int. J. Androl. , vol.34 , pp. e2-e6
    • Rajpert-De Meyts, E.1    Skakkebaek, N.E.2
  • 75
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic
    • Ranieri G., Patruno R., Ruggirei E., Montemurro S., Valerio P., Ribatti D. Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic. Curr. Med. Chem. 2006, 1:1845-1847.
    • (2006) Curr. Med. Chem. , vol.1 , pp. 1845-1847
    • Ranieri, G.1    Patruno, R.2    Ruggirei, E.3    Montemurro, S.4    Valerio, P.5    Ribatti, D.6
  • 76
    • 84913592964 scopus 로고
    • Possible carcinoma-in-situ of the testis
    • Skakkebaek N.E. Possible carcinoma-in-situ of the testis. Lancet 1972, 2:2516-2517.
    • (1972) Lancet , vol.2 , pp. 2516-2517
    • Skakkebaek, N.E.1
  • 77
    • 0023243854 scopus 로고
    • Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma
    • Skakkebaek N.E., Berthelsen J.G., Giwercman A., Muller J. Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. Int. J. Androl. 1987, 10:19-28.
    • (1987) Int. J. Androl. , vol.10 , pp. 19-28
    • Skakkebaek, N.E.1    Berthelsen, J.G.2    Giwercman, A.3    Muller, J.4
  • 78
    • 0026067317 scopus 로고
    • Expression of the c-kit proto-oncogene in the murine male germ cells
    • Sorrentino V., Giorgi M., Geremia R., Besmer P., Rossi P. Expression of the c-kit proto-oncogene in the murine male germ cells. Oncogene 1991, 6:149-151.
    • (1991) Oncogene , vol.6 , pp. 149-151
    • Sorrentino, V.1    Giorgi, M.2    Geremia, R.3    Besmer, P.4    Rossi, P.5
  • 79
    • 84884919309 scopus 로고    scopus 로고
    • Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors
    • Staibano S., Ilardi G., Leone V., Luise C., Merolla F., Esposito F., et al. Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors. BMC Cancer 2013, 13:433.
    • (2013) BMC Cancer , vol.13 , pp. 433
    • Staibano, S.1    Ilardi, G.2    Leone, V.3    Luise, C.4    Merolla, F.5    Esposito, F.6
  • 81
    • 0032472915 scopus 로고    scopus 로고
    • AIM-1: a mammalian midbody-associated protein required forcytokinesis
    • Terada Y., Tatsuka M., Suzuki F., Yasuda Y., Fujita S., Otsu M.A. AIM-1: a mammalian midbody-associated protein required forcytokinesis. EMBO J. 1998, 17:667-676.
    • (1998) EMBO J. , vol.17 , pp. 667-676
    • Terada, Y.1    Tatsuka, M.2    Suzuki, F.3    Yasuda, Y.4    Fujita, S.5    Otsu, M.A.6
  • 82
    • 13244279497 scopus 로고    scopus 로고
    • Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues
    • Ulbright T.M. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod. Pathol. 2005, 18:S61-S79.
    • (2005) Mod. Pathol. , vol.18 , pp. S61-S79
    • Ulbright, T.M.1
  • 84
    • 0141453090 scopus 로고    scopus 로고
    • Laboratory markers and germ cell tumors
    • von Eyben F.E. Laboratory markers and germ cell tumors. Crit. Rev. Clin. Lab. Sci. 2003, 40:377-427.
    • (2003) Crit. Rev. Clin. Lab. Sci. , vol.40 , pp. 377-427
    • von Eyben, F.E.1
  • 85
    • 33646056975 scopus 로고    scopus 로고
    • A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors
    • Voorhoeve P.M., le Sage C., Schrier M., Gillis A.J., Stoop H., Nagel R., et al. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 2006, 124:1169-1181.
    • (2006) Cell , vol.124 , pp. 1169-1181
    • Voorhoeve, P.M.1    le Sage, C.2    Schrier, M.3    Gillis, A.J.4    Stoop, H.5    Nagel, R.6
  • 86
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: an old idea-a paradigm shift
    • Wicha M.S., Liu S., Dontu G. Cancer stem cells: an old idea-a paradigm shift. Cancer Res. 2006, 66:1883-1890.
    • (2006) Cancer Res. , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 88
    • 27644584796 scopus 로고    scopus 로고
    • Update on angiogenesis inhibitors
    • Zakarija A., Soff G. Update on angiogenesis inhibitors. Curr. Opin. Oncol. 2005, 6:578-583.
    • (2005) Curr. Opin. Oncol. , vol.6 , pp. 578-583
    • Zakarija, A.1    Soff, G.2


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