RNA-binding protein LIN28 is a marker for testicular germ cell tumors

Human Pathology

Volumn 42, Issue 5, 2011, Pages 710-718

  Cao, Dengfeng ^a   Allan, Robert W ^b   Cheng, Liang ^c   Peng, Yan ^d   Guo, Charles C ^e   Dahiya, Neha ^a   Akhi, Shirin ^a   Li, Jianping ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c INDIANA UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

Embryonal carcinomas; LIN28; Seminomas; Testicular germ cell tumors; Yolk sac tumors

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN LIN28; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ADRENAL CORTEX CARCINOMA; ANTIGEN SPECIFICITY; ARTICLE; BILE DUCT CARCINOMA; BREAST CARCINOMA; BURKITT LYMPHOMA; CHORIOCARCINOMA; EMBRYONAL CARCINOMA; ESOPHAGEAL ADENOCARCINOMA; EWING SARCOMA; FIBROSARCOMA; FOLLICULAR LYMPHOMA; GERM CELL TUMOR; GRANULOCYTIC SARCOMA; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARGE CELL LYMPHOMA; LEIOMYOSARCOMA; LIVER CELL CARCINOMA; LYMPHOBLASTOMA; MAJOR CLINICAL STUDY; MALE; MANTLE CELL LYMPHOMA; MARGINAL ZONE LYMPHOMA; METASTASIS; NERVE SHEATH TUMOR; OSTEOSARCOMA; PLASMACYTOMA; RHABDOMYOSARCOMA; STAINING; STOMACH ADENOCARCINOMA; SYNOVIAL SARCOMA; TERATOMA; YOLK SAC TUMOR;

CARCINOMA, EMBRYONAL; ENDODERMAL SINUS TUMOR; HUMANS; MALE; NEOPLASMS, GERM CELL AND EMBRYONAL; RNA-BINDING PROTEINS; SEMINOMA; SENSITIVITY AND SPECIFICITY; SPERMATOZOA; TERATOMA; TESTICULAR NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 79954589258     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2010.09.007     Document Type: Article

References (20)

1. Ambros V., and Horvitz H.R. Heterochronic mutants of the nematode Caenorhabditis elegans Science 226 1984 409 416
2. Viswanathan S.R., and Daley G.Q. Lin28: a microRNA regulator with a macro role Cell 140 2010 445 449
3. Polesskaya A., Cuvellier S., and Naguibneva I. Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency Genes Dev 21 2007 1125 1138 (Pubitemid 46686480)
4. Richards M., Tan S.P., and Tan J.H. The transcriptome profile of human embryonic stem cells as defined by SAGE Stem Cells 22 2004 51 64 (Pubitemid 38018781)
5. Qiu C., Ma Y., Wang J., and Peng S. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells Nucleic Acids Res 38 2010 1240 1248
6. Yu J., Vodyanik M.A., and Smuga-Otto K. Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
7. Zhou Q., Chipperfield H., and Melton D.A. A gene regulatory network in mouse embryonic stem cells Proc Natl Acad Sci USA 104 2007 16438 16443 (Pubitemid 350211036)
8. Jones T.D., Ulbright T.M., and Eble J.N. OCT4 staining in testicular tumors: a sensitive and specific marker for seminoma and embryonal carcinoma Am J Surg Pathol 28 2004 935 940 (Pubitemid 38856851)
9. Santagata S., Ligon K.L., and Hornick J.L. Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors Am J Surg Pathol 31 2007 836 845 (Pubitemid 47165136)
10. West J.A., Viswanathan S.R., and Yabuuchi A. A role for Lin28 in primordial germ-cell development and germ cell malignancy Nature 460 2009 909 913
11. Cao D., Li J., and Guo C.C. SALL4 is a novel diagnostic marker for testicular germ cell tumors Am J Surg Pathol 33 2009 1065 1077
12. Cao D., Humphrey P.A., and Allan R.W. SALL4 is a novel sensitive and specific marker for metastatic germ cell tumors, with particular utility in detection of metastatic yolk sac tumors Cancer 115 2009 2640 2651
13. Melton C., Judson R.L., and Blelloch R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells Nature 463 2010 621 626
14. Balzer B.L., and Ulbright T.M. Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases Am J Surg Pathol 30 2006 858 865 (Pubitemid 44264976)
15. Wang P., Li J., and Allan R.W. Expression of UTF1 in primary and metastatic testicular germ cell tumors Am J Clin Pathol 134 2010 604 612
16. Cao D., Lane Z., and Allan R.W. TCL1 is a novel diagnostic marker for intratubular germ cell neoplasia and classic seminoma Histopathology 57 2010 152 157
17. Lau S.K., Weiss L.M., and Chu P.G. TCL1 protein expression in testicular germ cell tumors Am J Clin Pathol 133 2010 762 766
18. Liu A., Cheng L., and Du J. Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors Am J Surg Pathol 34 2010 697 706
19. Berney D.M., Shamash J., and Pieroni K. Loss of CD30 expression in metastatic embryonal carcinoma: the effects of chemotherapy? Histopathology 39 2001 382 385 (Pubitemid 32990089)
20. Zheng K., Wu X., and Kaestner K.H. The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse BMC Dev Biol 9 2009 38