17-β-estradiol elicits genomic and non-genomic responses in mouse male germ cells

Journal of Cellular Physiology

Volumn 206, Issue 1, 2006, Pages 238-245

  Vicini, Elena ^a   Loiarro, Maria ^b   Di Agostino, Silvia ^b   Corallini, Serena ^a   Capolunghi, Federica ^b   Carsetti, Rita ^b   Chieffi, Paolo ^c   Geremia, Raffaele ^b   Stefanini, Mario ^a   Sette, Claudio ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; ESTRADIOL; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROGESTERONE; STEROID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOMICS; GERM CELL; HORMONAL REGULATION; MALE; MEIOSIS; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPERMATOCYTE; SPERMATOGENESIS; TESTIS;

ANIMALS; APOPTOSIS; CELL LINE; CELLS, CULTURED; ENZYME ACTIVATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENES, REPORTER; GERM CELLS; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; SPERMATOCYTES; TRANS-ACTIVATION (GENETICS);

ANIMALIA;

EID: 28444487151     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20454     Document Type: Article

References (40)

1. Aschim EL, Saether T, Wiger R, Grotmol T, Haugen TB. 2004. Differential distribution of splice variants of estrogen receptor beta in human testicular cells suggests specific functions in spermatogenesis. J Steroid Biochem Mol Biol 92:97-106.
2. Auricchio F, Di Domenico M, Migliaccio A, Castoria G, Bilancio A. 1995. The role of estradiol receptor in the proliferative activity of vanadate on MCF-7 cells. Cell Growth Differ 6:105-113.
3. Carreau S. 2002. The testicular aromatase: From gene pto physiological role. Reprod Biol 2:5-12.
4. Castoria G, Migliaccio A, Bilancio A, Di Domenico M, de Falco A, Lombardi M, Fiorentino R, Varricchio L, Barone MV, Auricchio F. 2001. PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J 20:6050-6059.
5. Chieffi P, Kisslinger A, Sinisi AA, Abbondanza C, Tramontano D. 2003. 17beta-estradiol induced activation of ERK1/2 through endogenous androgen receptor-estradiol receptor alpha-Src complex in human prostate cells. Int J Oncol 23: 797-801.
6. Couse JF, Korach KS. 2004. Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract. Toxicology 205:55-63.
7. Couse JF, Hewitt SC, Bunch DO, Sar M, Walker VR, Davis BJ, Korach KS. 1999. Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta. Science 286:2328-2331.
8. Delbes G, Levacher C, Pairault C, Racine C, Duquenne C, Krust A, Habert R. 2004. Estrogen receptor beta-mediated inhibition of male germ cell line development in mice by endogenous estrogens during perinatal life. Endocrinology 145:3395-3403.
9. Di Agostino S, Rossi P, Geremia R, Sette C. 2002. The MAPK pathway triggers activation of Nek2 during chromosome condensation in mouse spermatocytes. Development 129:1715-1727.
10. Di Agostino S, Botti F, Di Carlo A, Sette C, Geremia R. 2004a. Meiotic progression of isolated mouse spermatocytes under simulated microgravity. Reproduction 128:25-32.
11. Di Agostino S, Fedele M, Chieffi P, Fusco A, Rossi P, Geremia R, Sette C. 2004b. Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes. Mol Biol Cell 15: 1224-1232.
12. Driggers PH, Segars TH. 2002. Estrogen action and cytoplasmic signaling pathways. Part II: The role of growth factors and phosphorylation in estrogen signaling. Trends Endocrinol Metab 13:422-427.
13. Ebling FJ, Brooks AN, Cronin AS, Ford H, Kerr JB. 2000. Estrogenic induction of spermatogenesis in the hypogonadal mouse. Endocrinology 141:2861-2869.
14. Free MJ, Jaffe RA. 1979. Collection of rete testis fluid from rats without previous efferent duct ligation. Biol Reprod 20:269-278.
15. Giguere V. 2002. To ERR in the estrogen pathway. Trends Endocrinol Metab 13: 220-225.
16. Hess RA, Bunick D, Lee KH, Bahr J, Taylor JA, Korach KS, Lubahn DB. 1997. A role for oestrogens in the male reproductive system. Nature 390:509-512.
17. Hewitt SC, Korach KS. 2003. Oestrogen receptor knockout mice: Roles for oestrogen receptors alpha and beta in reproductive tissues. Reproduction 125: 143-149.
18. Hirvonen-Santti SJ, Rannikko A, Santti H, Savolainen S, Nyberg M, Janne OA, Palvimo JJ. 2003. Down-regulation of estrogen receptor beta and transcriptional coregulator SNURF/RNF4 in testicular germ cell cancer. Eur Urol 44: 742-747.
19. Hofmann MC, Narisawa S, Hess RA, Millan JL. 1992. Immortalization of germ cells and somatic testicular cells using the SV40 large T antigen. Exp Cell Res 201:417-435.
20. Honda S, Harada N, Ito S, Takagi Y, Maeda S. 1998. Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene. Biochem Biophys Res Commun 252:445-449.
21. Jefferson WN, Couse JF, Banks EP, Korach KS, Newbold RR. 2000. Expression of estrogen receptor beta is developmentally regulated in reproductive tissues of male and female mice. Biol Reprod 62:310-317.
22. Meistrich M.L. 1977. Separation of spermatogenic cells and nuclei from rodent testes. Methods Cell Biol 15:15-54.
23. Migliaccio A, Castoria G, Di Domenico M, de Falco A, Bilancio A, Lombardi M, Barone MV, Ametrano D, Zannini MS, Abbondanza C, Auricchio F. 2000. Steroid-induced androgen receptoroestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J 19:5406-5417.
24. Migliaccio A, Castoria G, Di Domenico M, De Falco A, Bilancio A, Lombardi M, Bottero D, Varricchio L, Nanayakkara M, Rotondi A, Auricchio F. 2004. Sex steroid hormones act as growth factors. J Steroid Biochem Mol Biol 83:31-35.
25. Mishra DP, Shaha C. 2005. Estrogen-induced spermatogenic cell apoptosis occurs via the mitochondrial pathway: Role of superoxide and nitric oxide. J Biol Chem 280:6181-6196.
26. Murata Y, Robertson KM, Jones ME, Simpson ER. 2002. Effect of estrogen deficiency in the male: The ArKO mouse model. Mol Cell Endocrinol 193:7-12.
27. Newbold R. 1995. Cellular and molecular effects of developmental exposure to diethylstilbestrol: Implications for other environmental estrogens. Environ Health Perspect 103 Suppl 7:83-87.
28. O'Lone R, Frith MC, Karlsson EK, Hansen U. 2004. Genomic targets of nuclear estrogen receptors. Mol Endocrinol 18:1859-1875.
29. Pais V, Leav I, Lau KM, Jiang Z, Ho SM. 2003. Estrogen receptor-beta expression in human testicular germ cell tumors. Clin Cancer Res 9:4475-4482.
30. Robertson KM, O'Donnell L, Jones ME, Meachem SJ, Boon WC, Fisher CR, Graves KH, McLachlan RI, Simpson ER. 1999. Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. Proc Natl Acad Sci USA 96:7986-7991.
31. Rossi P, Dolci S, Albanesi C, Grimaldi P, Ricca R, Geremia R. 1993. Follicle-stimulating hormone induction of steel factor (SLF) mRNA in mouse Sertoli cells and stimulation of DNA synthesis in spermatogonia by soluble SLF. Dev Biol 155:68-74.
32. Rossi P, Dolci S, Sette C, Capolunghi F, Pellegrini M, Loiarro M, Di Agostino S, Paronetto MP, Grimaldi P, Merico D, Martegani E, Geremia R. 2004. Analysis of the gene expression profile of mouse male meiotic germ cells. Gene Expr Patterns 4:267-281.
33. Schlecht U, Demougin P, Koch R, Hermida L, Wiederkehr C, Descombes P, Pineau C, Jegou B, Primig M. 2004. Expression profiling of mammalian male meiosis and gametogenesis identifies novel candidate genes for roles in the regulation of fertility. Mol Biol Cell 15:1031-1043.
34. Selva DM, Tirado OM, Toran N, Suarez-Quian CA, Reventes J, Munell F. 2004. Estrogen receptor beta expression and apoptosis of spermatocytes of mice overexpressing a rat androgen binding protein transgene. Biol Reprod 71: 1461-1468.
35. Sette C, Barchi M, Bianchini A, Conti M, Rossi P, Geremia R. 1999. Activation of the mitogen-activated protein kinase ERK1 during meiotic progression of mouse pachytene spermatocytes. J Biol Chem 274:33571-33579.
36. Sharpe RM. 1993. Declining sperm counts in men-is there an endocrine cause? J Endocrinol 136:357-360.
37. Sharpe RM. 2003. The Oestrogen hypothesis'-where do we stand now? Int J Androl 26:2-15.
38. Shima JE, McLean DJ, McCarrey JR, Griswold MD. 2004. The murine testicular transcriptome: Characterizing gene expression in the testis during the progression of spermatogenesis. Biol Reprod 71:319-330.
39. Tirado OM, Selva DM, Toran N, Suarez-Quian CA, Jansen M, McDonnell DP, Reventos J, Munell F. 2004. Increased expression of estrogen receptor beta in pachytene spermatocytes after short term methoxyacetic acid administration. J Androl 25:84-94.
40. Weisz A, Bresciani F. 1993. Estrogen regulation of proto-oncogenes coding for nuclear proteins. Crit Rev Oncog 4:361-388.