The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway

Cell Metabolism

Volumn 20, Issue 3, 2014, Pages 512-525

  Vernia, Santiago ^a   Cavanagh Kyros, Julie ^a,b   Garcia Haro, Luisa ^a,d   Sabio, Guadalupe ^c   Barrett, Tamera ^a,b   Jung, Dae Young ^a   Kim, Jason K ^a   Xu, Jia ^a,e   Shulha, Hennady P ^a   Garber, Manuel ^a   Gao, Guangping ^a   Davis, Roger J ^a,b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e KEW Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 21; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN KINASE B; RECEPTOR INTERACTING PROTEIN 140; STRESS ACTIVATED PROTEIN KINASE; FIBROBLAST GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY MASS; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FATTY ACID OXIDATION; FATTY LIVER; GENE EXPRESSION; GLUCOSE TOLERANCE; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; KETOGENESIS; LIVER CELL; LIVER METABOLISM; METABOLIC REGULATION; MITOCHONDRIAL VOLUME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXYGEN CONSUMPTION; PEROXISOME; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; GENE DELETION; GENETICS; LIPID DIET; LIVER; MALE; METABOLISM;

ANIMALS; DIET, HIGH-FAT; FIBROBLAST GROWTH FACTORS; GENE DELETION; INSULIN RESISTANCE; LIVER; MALE; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; OBESITY; PPAR ALPHA;

EID: 84913590552     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.06.010     Document Type: Article

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