메뉴 건너뛰기




Volumn 45, Issue , 2014, Pages 495-517

On the nature and evolutionary impact of phenotypic robustness mechanisms

Author keywords

canalization; conditional neutrality; cryptic genetic variation; epistasis; genotype networks; macroenvironmental variation; microenvironmental variation; mutational robustness; phenotypic plasticity

Indexed keywords

CANALIZATION (BIOLOGY); CRYPSIS; EPISTASIS; EVOLUTIONARY BIOLOGY; GENETIC VARIATION; PHENOTYPE; PHENOTYPIC PLASTICITY; PHYSIOLOGY;

EID: 84913536210     PISSN: 1543592X     EISSN: 15452069     Source Type: Book Series    
DOI: 10.1146/annurev-ecolsys-120213-091705     Document Type: Article
Times cited : (59)

References (129)
  • 1
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: Theory and experimental approaches
    • Alon U. 2007. Network motifs: theory and experimental approaches. Nat. Rev. Genet. 8:450-61
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 450-461
    • Alon, U.1
  • 2
    • 0034667684 scopus 로고    scopus 로고
    • Plasticity, evolvability, and modularity in RNA
    • Ancel LW, FontanaW. 2000. Plasticity, evolvability, and modularity in RNA. J. Exp. Zool. 288:242-83
    • (2000) J. Exp. Zool. , vol.288 , pp. 242-283
    • Ancel, L.W.1    Fontana, W.2
  • 3
    • 0001410750 scopus 로고
    • A new factor in evolution
    • Baldwin JM. 1896. A new factor in evolution. Am. Nat. 30:441-51
    • (1896) Am. Nat. , vol.30 , pp. 441-451
    • Baldwin, J.M.1
  • 4
    • 33745287724 scopus 로고    scopus 로고
    • Noise in protein expression scales with natural protein abundance
    • Bar-Even A, Paulsson J,Maheshri N, Carmi M, O'Shea E, et al. 2006. Noise in protein expression scales with natural protein abundance. Nat. Genet. 38:636-43
    • (2006) Nat. Genet. , vol.38 , pp. 636-643
    • Bar-Even, A.1    Paulsson Jmaheshri, N.2    Carmi, M.3    O'Shea, E.4
  • 5
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • Becskei A, Serrano L. 2000. Engineering stability in gene networks by autoregulation. Nature 405:590-93
    • (2000) Nature , vol.405 , pp. 590-593
    • Becskei, A.1    Serrano, L.2
  • 6
    • 0344120676 scopus 로고    scopus 로고
    • Phenotypic plasticity can potentiate rapid evolutionary change
    • Behera N, Nanjundiah V. 2004. Phenotypic plasticity can potentiate rapid evolutionary change. J. Theor. Biol. 226:177-84
    • (2004) J. Theor. Biol. , vol.226 , pp. 177-184
    • Behera, N.1    Nanjundiah, V.2
  • 7
    • 60749101583 scopus 로고    scopus 로고
    • A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning
    • Benazet JD, Bischofberger M, Tiecke E, Goncalves A, Martin JF, et al. 2009. A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning. Science 323:1050-53
    • (2009) Science , vol.323 , pp. 1050-1053
    • Benazet, J.D.1    Bischofberger, M.2    Tiecke, E.3    Goncalves, A.4    Martin, J.F.5
  • 8
    • 0042154192 scopus 로고    scopus 로고
    • Evolutionary capacitance as a general feature of complex gene networks
    • Bergman A, SiegalML. 2003. Evolutionary capacitance as a general feature of complex gene networks. Nature 424:549-52
    • (2003) Nature , vol.424 , pp. 549-552
    • Bergman, A.1    Siegal, M.L.2
  • 11
    • 34447537179 scopus 로고    scopus 로고
    • Evolution favors protein mutational robustness in sufficiently large populations
    • Bloom JD, Lu Z, Chen D, Raval A, Venturelli OS, Arnold FH. 2007. Evolution favors protein mutational robustness in sufficiently large populations. BMC Biol. 5:29
    • (2007) BMC Biol. , vol.5 , pp. 29
    • Bloom, J.D.1    Lu, Z.2    Chen, D.3    Raval, A.4    Venturelli, O.S.5    Arnold, F.H.6
  • 12
    • 33646240072 scopus 로고    scopus 로고
    • Direct evolution of genetic robustness inmicroRNA
    • Borenstein E, Ruppin E. 2006. Direct evolution of genetic robustness inmicroRNA. Proc. Natl. Acad. Sci. USA 103:6593-98
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6593-6598
    • Borenstein, E.1    Ruppin, E.2
  • 13
    • 3142755598 scopus 로고    scopus 로고
    • Epistasis and its relationship to canalization in the RNA virus6
    • Burch CL, Chao L. 2004. Epistasis and its relationship to canalization in the RNA virus6. Genetics 167:559-67
    • (2004) Genetics , vol.167 , pp. 559-567
    • Burch, C.L.1    Chao, L.2
  • 14
    • 84876991257 scopus 로고    scopus 로고
    • Promoter sequence determines the relationship between expression level and noise
    • Carey LB, vanDijkD, Sloot PM, Kaandorp JA, Segal E. 2013. Promoter sequence determines the relationship between expression level and noise. PLOS Biol. 11:e1001528
    • (2013) PLOS Biol. , vol.11 , pp. e1001528
    • Carey, L.B.1    Van Dijk, D.2    Sloot, P.M.3    Kaandorp, J.A.4    Segal, E.5
  • 15
    • 84894515914 scopus 로고    scopus 로고
    • MiR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor
    • Cassidy JJ, Jha AR, Posadas DM, Giri R, Venken KJ, et al. 2013. miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor. Cell 155:1556-67
    • (2013) Cell , vol.155 , pp. 1556-1567
    • Cassidy, J.J.1    Jha, A.R.2    Posadas, D.M.3    Giri, R.4    Venken, K.J.5
  • 16
    • 0031590454 scopus 로고    scopus 로고
    • A molecular aspect of symbiotic interactions between the weevil Sitophilus oryzae and its endosymbiotic bacteria: Over-expression of a chaperonin
    • Charles H, Heddi A, Guillaud J, Nardon C, Nardon P. 1997. A molecular aspect of symbiotic interactions between the weevil Sitophilus oryzae and its endosymbiotic bacteria: over-expression of a chaperonin. Biochem. Biophys. Res. Commun. 239:769-74
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 769-774
    • Charles, H.1    Heddi, A.2    Guillaud, J.3    Nardon, C.4    Nardon, P.5
  • 17
    • 84857424416 scopus 로고    scopus 로고
    • Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations
    • Chen B, Wagner A. 2012. Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations. BMC Evol. Biol. 12:25
    • (2012) BMC Evol. Biol. , vol.12 , pp. 25
    • Chen, B.1    Wagner, A.2
  • 18
    • 84859551640 scopus 로고    scopus 로고
    • Evolutionary rate covariation reveals shared functionality and coexpression of genes
    • Clark NL, Alani E, Aquadro CF. 2012. Evolutionary rate covariation reveals shared functionality and coexpression of genes. Genome Res. 22:714-20
    • (2012) Genome Res. , vol.22 , pp. 714-720
    • Clark, N.L.1    Alani, E.2    Aquadro, C.F.3
  • 19
    • 33749392167 scopus 로고    scopus 로고
    • Effect of random and hub gene disruptions on environmental and mutational robustness in Escherichia coli
    • Cooper TF, Morby AP, Gunn A, Schneider D. 2006. Effect of random and hub gene disruptions on environmental and mutational robustness in Escherichia coli. BMC Genomics 7:237
    • (2006) BMC Genomics , vol.7 , pp. 237
    • Cooper, T.F.1    Morby, A.P.2    Gunn, A.3    Schneider, D.4
  • 20
    • 84857950781 scopus 로고    scopus 로고
    • Negative feedback confers mutational robustness in yeast transcription factor regulation
    • Denby CM, Im JH, Yu RC, Pesce CG, Brem RB. 2012. Negative feedback confers mutational robustness in yeast transcription factor regulation. Proc. Natl. Acad. Sci. USA 109:3874-78
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 3874-3878
    • Denby, C.M.1    Im, J.H.2    Yu, R.C.3    Pesce, C.G.4    Brem, R.B.5
  • 22
    • 0033529041 scopus 로고    scopus 로고
    • Cause and effect in evolution
    • DickinsonWJ, Seger J. 1999. Cause and effect in evolution. Nature 399:30
    • (1999) Nature , vol.399 , pp. 30
    • Dickinson, W.J.1    Seger, J.2
  • 24
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Proj. Consort
    • ENCODE Proj. Consort., Bernstein BE, Birney E, Dunham I, Green ED, et al. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature 489:57-74
    • (2012) Nature , vol.489 , pp. 57-74
    • Bernstein, B.E.1    Birney, E.2    Dunham, I.3    Green, E.D.4
  • 25
    • 4143121171 scopus 로고    scopus 로고
    • GroEL and the maintenance of bacterial endosymbiosis
    • Fares MA, Moya A, Barrio E. 2004. GroEL and the maintenance of bacterial endosymbiosis. Trends Genet. 20:413-16
    • (2004) Trends Genet. , vol.20 , pp. 413-416
    • Fares, M.A.1    Moya, A.2    Barrio, E.3
  • 27
    • 78649761770 scopus 로고    scopus 로고
    • Evolutionary innovations and the organization of protein functions in genotype space
    • Ferrada E, Wagner A. 2010. Evolutionary innovations and the organization of protein functions in genotype space. PLOS ONE 5:e14172
    • (2010) PLOS ONE , vol.5 , pp. e14172
    • Ferrada, E.1    Wagner, A.2
  • 28
    • 84859919548 scopus 로고    scopus 로고
    • A comparison of genotype-phenotype maps for RNA and proteins
    • Ferrada E, Wagner A. 2012. A comparison of genotype-phenotype maps for RNA and proteins. Biophys. J. 102:1916-25
    • (2012) Biophys. J. , vol.102 , pp. 1916-1925
    • Ferrada, E.1    Wagner, A.2
  • 29
    • 62449123034 scopus 로고    scopus 로고
    • A chance at survival: Gene expression noise and phenotypic diversification strategies
    • Fraser D, Kærn M. 2009. A chance at survival: gene expression noise and phenotypic diversification strategies. Mol. Microbiol. 71:1333-40
    • (2009) Mol. Microbiol. , vol.71 , pp. 1333-1340
    • Fraser, D.1    Kærn, M.2
  • 31
    • 77649168145 scopus 로고    scopus 로고
    • The quantitative genetics of phenotypic robustness
    • Fraser HB, Schadt EE. 2010. The quantitative genetics of phenotypic robustness. PLOS ONE 5:e8635
    • (2010) PLOS ONE , vol.5 , pp. e8635
    • Fraser, H.B.1    Schadt, E.E.2
  • 32
    • 0034676456 scopus 로고    scopus 로고
    • Feedback control of intercellular signalling in development
    • Freeman M. 2000. Feedback control of intercellular signalling in development. Nature 408:313-19
    • (2000) Nature , vol.408 , pp. 313-319
    • Freeman, M.1
  • 33
    • 79251560849 scopus 로고    scopus 로고
    • Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation
    • Gangaraju VK, Yin H, Weiner MM, Wang J, Huang XA, Lin H. 2011. Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation. Nat. Genet. 43:153-58
    • (2011) Nat. Genet. , Issue.43 , pp. 153-158
    • Gangaraju, V.K.1    Yin, H.2    Weiner, M.M.3    Wang, J.4    Huang, X.A.5    Lin, H.6
  • 35
    • 58549096683 scopus 로고    scopus 로고
    • Decanalization and the origin of complex disease
    • Gibson G. 2009. Decanalization and the origin of complex disease. Nat. Rev. Genet. 10:134-40
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 134-140
    • Gibson, G.1
  • 36
    • 65549084298 scopus 로고    scopus 로고
    • Potential role of phenotypic mutations in the evolution of protein expression and stability
    • Goldsmith M, Tawfik DS. 2009. Potential role of phenotypic mutations in the evolution of protein expression and stability. Proc. Natl. Acad. Sci. USA 106:6197-202
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 6197-6202
    • Goldsmith, M.1    Tawfik, D.S.2
  • 37
    • 67651230677 scopus 로고    scopus 로고
    • Complex adaptations can drive the evolution of the capacitor [PSI+], even with realistic rates of yeast sex
    • Griswold CK, Masel J. 2009. Complex adaptations can drive the evolution of the capacitor [PSI+], even with realistic rates of yeast sex. PLOS Genet. 5:e1000517
    • (2009) PLOS Genet. , vol.5 , pp. e1000517
    • Griswold, C.K.1    Masel, J.2
  • 38
    • 0022410121 scopus 로고
    • Limits of adaptation: The evolution of selective neutrality
    • HartlDL, DykhuizenDE, Dean AM. 1985. Limits of adaptation: the evolution of selective neutrality. Genetics 111:655-74
    • (1985) Genetics , vol.111 , pp. 655-674
    • Hartl, D.L.1    Dykhuizen, D.E.2    Dean, A.M.3
  • 39
    • 79957944389 scopus 로고    scopus 로고
    • Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme
    • Hayden EJ, Ferrada E, Wagner A. 2011. Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme. Nature 474:92-95
    • (2011) Nature , vol.474 , pp. 92-95
    • Hayden, E.J.1    Ferrada, E.2    Wagner, A.3
  • 40
    • 11244329008 scopus 로고    scopus 로고
    • The population genetic theory of hidden variation and genetic robustness
    • Hermisson J, Wagner GP. 2004. The population genetic theory of hidden variation and genetic robustness. Genetics 168:2271-84
    • (2004) Genetics , vol.168 , pp. 2271-2284
    • Hermisson, J.1    Wagner, G.P.2
  • 42
    • 77954697226 scopus 로고    scopus 로고
    • Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis
    • Hilgers V, Bushati N, Cohen SM. 2010. Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. PLOS Biol. 8:e1000396
    • (2010) PLOS Biol. , vol.8 , pp. e1000396
    • Hilgers, V.1    Bushati, N.2    Cohen, S.M.3
  • 43
    • 84984765621 scopus 로고    scopus 로고
    • Canalization of development by microRNAs
    • Hornstein E, Shomron N. 2006. Canalization of development by microRNAs. Nat. Genet. 38(Suppl.):S20-24
    • (2006) Nat. Genet. , vol.38 , pp. S20-24
    • Hornstein, E.1    Shomron, N.2
  • 45
    • 84876090882 scopus 로고    scopus 로고
    • Hsp90 regulates nongenetic variation in response to environmental stress
    • Hsieh YY, Hung PH, Leu JY. 2013. Hsp90 regulates nongenetic variation in response to environmental stress. Mol. Cell 50:82-92
    • (2013) Mol. Cell , vol.50 , pp. 82-92
    • Hsieh, Y.Y.1    Hung, P.H.2    Leu, J.Y.3
  • 46
    • 78650644709 scopus 로고    scopus 로고
    • Hsp90 and environmental stress transform the adaptive value of natural genetic variation
    • Jarosz DF, Lindquist S. 2010. Hsp90 and environmental stress transform the adaptive value of natural genetic variation. Science 330:1820-24
    • (2010) Science , vol.330 , pp. 1820-1824
    • Jarosz, D.F.1    Lindquist, S.2
  • 47
    • 78149452881 scopus 로고    scopus 로고
    • Protein homeostasis and the phenotypic manifestation of genetic diversity: Principles and mechanisms
    • Jarosz DF, Taipale M, Lindquist S. 2010. Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms. Annu. Rev. Genet. 44:189-216
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 189-216
    • Jarosz, D.F.1    Taipale, M.2    Lindquist, S.3
  • 48
    • 0019869334 scopus 로고
    • The molecular basis of dominance
    • Kacser H, Burns JA. 1981. The molecular basis of dominance. Genetics 97:639-66
    • (1981) Genetics , vol.97 , pp. 639-666
    • Kacser, H.1    Burns, J.A.2
  • 49
    • 0034076018 scopus 로고    scopus 로고
    • The evolution of genetic canalization under fluctuating selection
    • Kawecki TJ. 2000. The evolution of genetic canalization under fluctuating selection. Evolution 54:1-12
    • (2000) Evolution , vol.54 , pp. 1-12
    • Kawecki, T.J.1
  • 50
    • 1942452749 scopus 로고    scopus 로고
    • Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae
    • Kellis M, Birren BW, Lander ES. 2004. Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae. Nature 428:617-24
    • (2004) Nature , vol.428 , pp. 617-624
    • Kellis, M.1    Birren, B.W.2    Lander, E.S.3
  • 51
    • 77749271373 scopus 로고    scopus 로고
    • The spontaneous appearance rate of the yeast prion [PSI+] and its implications for the evolution of the evolvability properties of the [PSI+] system
    • Lancaster AK, Bardill JP, True HL, Masel J. 2010. The spontaneous appearance rate of the yeast prion [PSI+] and its implications for the evolution of the evolvability properties of the [PSI+] system. Genetics 184:393-400
    • (2010) Genetics , vol.184 , pp. 393-400
    • Lancaster, A.K.1    Bardill, J.P.2    True, H.L.3    Masel, J.4
  • 52
    • 84866780561 scopus 로고    scopus 로고
    • The genotype-phenotype maps of systems biology and quantitative genetics: Distinct and complementary
    • Landry CR, Rifkin SA. 2012. The genotype-phenotype maps of systems biology and quantitative genetics: distinct and complementary. Adv. Exp. Med. Biol. 751:371-98
    • (2012) Adv. Exp. Med. Biol. , vol.751 , pp. 371-398
    • Landry, C.R.1    Rifkin, S.A.2
  • 53
    • 84876406925 scopus 로고    scopus 로고
    • The role of mutational robustness in RNA virus evolution
    • Lauring AS, Frydman J, Andino R. 2013. The role of mutational robustness in RNA virus evolution. Nat. Rev. Microbiol. 11:327-36
    • (2013) Nat. Rev. Microbiol. , vol.11 , pp. 327-336
    • Lauring, A.S.1    Frydman, J.2    Andino, R.3
  • 54
    • 77949386270 scopus 로고    scopus 로고
    • Genes confer similar robustness to environmental, stochastic, and genetic perturbations in yeast
    • Lehner B. 2010. Genes confer similar robustness to environmental, stochastic, and genetic perturbations in yeast. PLOS ONE 5:e9035
    • (2010) PLOS ONE , vol.5 , pp. e9035
    • Lehner, B.1
  • 55
    • 56849091295 scopus 로고    scopus 로고
    • Network hubs buffer environmental variation in Saccharomyces cerevisiae
    • Levy SF, Siegal ML. 2008. Network hubs buffer environmental variation in Saccharomyces cerevisiae. PLOS Biol. 6:e264
    • (2008) PLOS Biol. , vol.6 , pp. e264
    • Levy, S.F.1    Siegal, M.L.2
  • 57
    • 84861544417 scopus 로고    scopus 로고
    • Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant
    • Levy SF, Ziv N, Siegal ML. 2012. Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant. PLOS Biol. 10:e1001325
    • (2012) PLOS Biol. , vol.10 , pp. e1001325
    • Levy, S.F.1    Ziv, N.2    Siegal, M.L.3
  • 58
    • 64249144494 scopus 로고    scopus 로고
    • A microRNA imparts robustness against environmental fluctuation during development
    • Li X, Cassidy JJ, Reinke CA, Fischboeck S, Carthew RW. 2009. A microRNA imparts robustness against environmental fluctuation during development. Cell 137:273-82
    • (2009) Cell , vol.137 , pp. 273-282
    • Li, X.1    Cassidy, J.J.2    Reinke, C.A.3    Fischboeck, S.4    Carthew, R.W.5
  • 59
    • 68149131144 scopus 로고    scopus 로고
    • Plasticity versus environmental canalization: Population differences in thermal responses along a latitudinal gradient in Drosophila serrata
    • Liefting M, Hoffmann AA, Ellers J. 2009. Plasticity versus environmental canalization: population differences in thermal responses along a latitudinal gradient in Drosophila serrata. Evolution 63:1954-63
    • (2009) Evolution , vol.63 , pp. 1954-1963
    • Liefting, M.1    Hoffmann, A.A.2    Ellers, J.3
  • 60
    • 79953886457 scopus 로고    scopus 로고
    • Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression
    • Macneil LT, Walhout AJ. 2011. Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression. Genome Res. 21:645-57
    • (2011) Genome Res. , vol.21 , pp. 645-657
    • MacNeil, L.T.1    Walhout, A.J.2
  • 62
    • 23344432509 scopus 로고    scopus 로고
    • Evolutionary capacitance may be favored by natural selection
    • Masel J. 2005. Evolutionary capacitance may be favored by natural selection. Genetics 170:1359-71
    • (2005) Genetics , vol.170 , pp. 1359-1371
    • Masel, J.1
  • 63
    • 33645232390 scopus 로고    scopus 로고
    • Cryptic genetic variation is enriched for potential adaptations
    • Masel J. 2006. Cryptic genetic variation is enriched for potential adaptations. Genetics 172:1985-91
    • (2006) Genetics , vol.172 , pp. 1985-1991
    • Masel, J.1
  • 64
    • 84884972869 scopus 로고    scopus 로고
    • Q&A: Evolutionary capacitance
    • Masel J. 2013. Qamp;A: evolutionary capacitance. BMC Biol. 11:103
    • (2013) BMC Biol. , vol.11 , pp. 103
    • Masel, J.1
  • 65
    • 0042031465 scopus 로고    scopus 로고
    • The evolution of the evolvability properties of the yeast prion [PSI+]
    • Masel J, Bergman A. 2003. The evolution of the evolvability properties of the yeast prion [PSI+]. Evolution 57:1498-512
    • (2003) Evolution , vol.57 , pp. 1498-1512
    • Masel, J.1    Bergman, A.2
  • 66
    • 69449106377 scopus 로고    scopus 로고
    • Robustness: Mechanisms and consequences
    • Masel J, Siegal ML. 2009. Robustness: mechanisms and consequences. Trends Genet. 25:395-403
    • (2009) Trends Genet. , vol.25 , pp. 395-403
    • Masel, J.1    Siegal, M.L.2
  • 67
    • 50049135016 scopus 로고    scopus 로고
    • Robustness promotes evolvability of thermotolerance in an RNA virus
    • McBride RC, Ogbunugafor CB, Turner PE. 2008. Robustness promotes evolvability of thermotolerance in an RNA virus. BMC Evol. Biol. 8:231
    • (2008) BMC Evol. Biol. , vol.8 , pp. 231
    • McBride, R.C.1    Ogbunugafor, C.B.2    Turner, P.E.3
  • 69
    • 55749086858 scopus 로고    scopus 로고
    • Intraspecific evolution of the intercellular signaling network underlying a robust developmental system
    • Milloz J, Duveau F, Nuez I, Felix MA. 2008. Intraspecific evolution of the intercellular signaling network underlying a robust developmental system. Genes Dev. 22:3064-75
    • (2008) Genes Dev. , vol.22 , pp. 3064-3075
    • Milloz, J.1    Duveau, F.2    Nuez, I.3    Felix, M.A.4
  • 71
    • 0026591963 scopus 로고
    • The evolutionary maintenance of alternative phenotypes
    • Moran NA. 1992. The evolutionary maintenance of alternative phenotypes. Am. Nat. 139:971-89
    • (1992) Am. Nat. , vol.139 , pp. 971-989
    • Moran, N.A.1
  • 72
    • 33745220278 scopus 로고    scopus 로고
    • Single-cell proteomic analysis of S. Cerevisiae reveals the architecture of biological noise
    • Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, et al. 2006. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature 441:840-46
    • (2006) Nature , vol.441 , pp. 840-846
    • Newman, J.R.1    Ghaemmaghami, S.2    Ihmels, J.3    Breslow, D.K.4    Noble, M.5
  • 73
    • 79952302623 scopus 로고    scopus 로고
    • The role of incoherent microRNA-mediated feedforward loops in noise buffering
    • Osella M, Bosia C, Cora D, Caselle M. 2011. The role of incoherent microRNA-mediated feedforward loops in noise buffering. PLOS Comput. Biol. 7:e1001101
    • (2011) PLOS Comput. Biol. , vol.7 , pp. e1001101
    • Osella, M.1    Bosia, C.2    Cora, D.3    Caselle, M.4
  • 75
    • 84899452541 scopus 로고    scopus 로고
    • Cryptic genetic variation: Evolution's hidden substrate
    • Paaby AB, Rockman MV. 2014. Cryptic genetic variation: evolution's hidden substrate. Nat. Rev. Genet. 15:247-58
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 247-258
    • Paaby, A.B.1    Rockman, M.V.2
  • 76
    • 79960003271 scopus 로고    scopus 로고
    • Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development
    • Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C. 2011. Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc. Natl. Acad. Sci. USA 108:10202-7
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 10202-10207
    • Paulsen, M.1    Legewie, S.2    Eils, R.3    Karaulanov, E.4    Niehrs, C.5
  • 77
    • 84857400300 scopus 로고    scopus 로고
    • Biological robustness and the role of microRNAs: A network perspective
    • PelaezN, Carthew RW. 2012. Biological robustness and the role of microRNAs: a network perspective. Curr. Top. Dev. Biol. 99:237-55
    • (2012) Curr. Top. Dev. Biol. , vol.99 , pp. 237-255
    • Pelaezn Carthew, R.W.1
  • 79
    • 54149088214 scopus 로고    scopus 로고
    • Epistasis-The essential role of gene interactions in the structure and evolution of genetic systems
    • Phillips PC. 2008. Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems. Nat. Rev. Genet. 9:855-67
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 855-867
    • Phillips, P.C.1
  • 80
    • 0038133117 scopus 로고    scopus 로고
    • Codon bias and frequency-dependent selection on the hemagglutinin epitopes of influenza A virus
    • Plotkin JB, Dushoff J. 2003. Codon bias and frequency-dependent selection on the hemagglutinin epitopes of influenza A virus. Proc. Natl. Acad. Sci. USA 100:7152-57
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7152-7157
    • Plotkin, J.B.1    Dushoff, J.2
  • 82
    • 2342423945 scopus 로고    scopus 로고
    • Detecting selection using a single genome sequence of M. Tuberculosis and P. Falciparum
    • Plotkin JB, Dushoff J, Fraser HB. 2004. Detecting selection using a single genome sequence of M. tuberculosis and P. falciparum. Nature 428:942-45
    • (2004) Nature , vol.428 , pp. 942-945
    • Plotkin, J.B.1    Dushoff, J.2    Fraser, H.B.3
  • 84
    • 0038161217 scopus 로고    scopus 로고
    • The role of phenotypic plasticity in driving genetic evolution
    • Price TD,Qvarnstrom A, IrwinDE. 2003. The role of phenotypic plasticity in driving genetic evolution. Proc. R. Soc. B-Biol. Sci. 270:1433-40
    • (2003) Proc. R. Soc. B-Biol. Sci. , vol.270 , pp. 1433-1440
    • Price Tdqvarnstrom, A.1    Irwin, D.E.2
  • 85
    • 33748311990 scopus 로고    scopus 로고
    • Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast
    • Ramsey SA, Smith JJ, Orrell D, Marelli M, Petersen TW, et al. 2006. Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast. Nat. Genet. 38:1082-87
    • (2006) Nat. Genet. , vol.38 , pp. 1082-1087
    • Ramsey, S.A.1    Smith, J.J.2    Orrell, D.3    Marelli, M.4    Petersen, T.W.5
  • 86
    • 2942718723 scopus 로고    scopus 로고
    • Control of stochasticity in eukaryotic gene expression
    • Raser JM, O'Shea EK. 2004. Control of stochasticity in eukaryotic gene expression. Science 304:1811-14
    • (2004) Science , vol.304 , pp. 1811-1814
    • Raser, J.M.1    O'Shea, E.K.2
  • 87
    • 84884644092 scopus 로고    scopus 로고
    • Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations
    • Richardson JB, Uppendahl LD, Traficante MK, Levy SF, Siegal ML. 2013. Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations. PLOS Genet. 9:e1003733
    • (2013) PLOS Genet. , vol.9 , pp. e1003733
    • Richardson, J.B.1    Uppendahl, L.D.2    Traficante, M.K.3    Levy, S.F.4    Siegal, M.L.5
  • 88
    • 84890110060 scopus 로고    scopus 로고
    • Cryptic variation in morphological evolution: HSP90 as a capacitor for loss of eyes in cavefish
    • Rohner N, Jarosz DF, Kowalko JE, YoshizawaM, Jeffery WR, et al. 2013. Cryptic variation in morphological evolution: HSP90 as a capacitor for loss of eyes in cavefish. Science 342:1372-75
    • (2013) Science , vol.342 , pp. 1372-1375
    • Rohner, N.1    Jarosz, D.F.2    Kowalko, J.E.3    Yoshizawa, M.4    Jeffery, W.R.5
  • 89
    • 0034546905 scopus 로고    scopus 로고
    • From genotype to phenotype: Buffering mechanisms and the storage of genetic information
    • Rutherford SL. 2000. From genotype to phenotype: buffering mechanisms and the storage of genetic information. Bioessays 22:1095-105
    • (2000) Bioessays , vol.22 , pp. 1095-1105
    • Rutherford, S.L.1
  • 90
    • 0032569851 scopus 로고    scopus 로고
    • Hsp90 as a capacitor for morphological evolution
    • Rutherford SL, Lindquist S. 1998. Hsp90 as a capacitor for morphological evolution. Nature 396:336-42
    • (1998) Nature , vol.396 , pp. 336-342
    • Rutherford, S.L.1    Lindquist, S.2
  • 91
    • 35748931551 scopus 로고    scopus 로고
    • Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels
    • Sangster TA, Bahrami A, Wilczek A, Watanabe E, Schellenberg K, et al. 2007. Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels. PLOS ONE 2:e648
    • (2007) PLOS ONE , vol.2 , pp. e648
    • Sangster, T.A.1    Bahrami, A.2    Wilczek, A.3    Watanabe, E.4    Schellenberg, K.5
  • 92
    • 1842782331 scopus 로고    scopus 로고
    • Under cover: Causes, effects and implications of Hsp90-mediated genetic capacitance
    • Sangster TA, Lindquist S, Queitsch C. 2004. Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance. Bioessays 26:348-62
    • (2004) Bioessays , vol.26 , pp. 348-362
    • Sangster, T.A.1    Lindquist, S.2    Queitsch, C.3
  • 96
    • 77955347080 scopus 로고    scopus 로고
    • A naturally occurring variant of Hsp90 that is associated with decanalization
    • Sgrò CM, Wegener B, Hoffmann AA. 2010 A naturally occurring variant of Hsp90 that is associated with decanalization. Proc. R. Soc. B-Biol. Sci. 277, 2049-57
    • (2010) Proc. R. Soc. B-Biol. Sci. , vol.277 , pp. 2049-2057
    • Sgrò, C.M.1    Wegener, B.2    Hoffmann, A.A.3
  • 97
    • 84874407310 scopus 로고    scopus 로고
    • Crouching variation revealed
    • Siegal ML. 2013. Crouching variation revealed. Mol. Ecol. 22:1187-89
    • (2013) Mol. Ecol. , vol.22 , pp. 1187-1189
    • Siegal, M.L.1
  • 98
    • 0036678862 scopus 로고    scopus 로고
    • Waddington's canalization revisited: Developmental stability and evolution
    • Siegal ML, Bergman A. 2002. Waddington's canalization revisited: developmental stability and evolution. Proc. Natl. Acad. Sci. USA 99:10528-32
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10528-10532
    • Siegal, M.L.1    Bergman, A.2
  • 99
    • 84857399819 scopus 로고    scopus 로고
    • Hsp90 depletion goes wild
    • Siegal ML, Masel J. 2012. Hsp90 depletion goes wild. BMC Biol. 10:14
    • (2012) BMC Biol. , vol.10 , pp. 14
    • Siegal, M.L.1    Masel, J.2
  • 100
    • 76349117871 scopus 로고    scopus 로고
    • Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons
    • Specchia V, Piacentini L, Tritto P, Fanti L, D'Alessandro R, et al. 2010. Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons. Nature 463:662-65
    • (2010) Nature , vol.463 , pp. 662-665
    • Specchia, V.1    Piacentini, L.2    Tritto, P.3    Fanti, L.4    D'Alessandro, R.5
  • 102
    • 0028980697 scopus 로고
    • The differential genetic and environmental canalization of fitness components in Drosophila melanogaster
    • Stearns SC, Kaiser M, Kawecki TJ. 1995. The differential genetic and environmental canalization of fitness components in Drosophila melanogaster. J. Evol. Biol. 8:539-57
    • (1995) J. Evol. Biol. , vol.8 , pp. 539-557
    • Stearns, S.C.1    Kaiser, M.2    Kawecki, T.J.3
  • 103
    • 0032998243 scopus 로고    scopus 로고
    • Codon bias and mutability in HIV sequences
    • Stephens CR,Waelbroeck H. 1999. Codon bias and mutability in HIV sequences. J. Mol. Evol. 48:390-97
    • (1999) J. Mol. Evol. , vol.48 , pp. 390-397
    • Stephens, C.R.1    Waelbroeck, H.2
  • 104
    • 0036065328 scopus 로고    scopus 로고
    • Metapopulation structure favors plasticity over local adaptation
    • Sultan SE, Spencer HG. 2002. Metapopulation structure favors plasticity over local adaptation. Am. Nat. 160:271-83
    • (2002) Am. Nat. , vol.160 , pp. 271-283
    • Sultan, S.E.1    Spencer, H.G.2
  • 105
    • 34548511143 scopus 로고    scopus 로고
    • New structural variation in evolutionary searches of RNA neutral networks
    • Sumedha, Martin OC, Wagner A. 2007. New structural variation in evolutionary searches of RNA neutral networks. Biosystems 90:475-85
    • (2007) Biosystems , vol.90 , pp. 475-485
    • Sumedha Martin, O.C.1    Wagner, A.2
  • 106
    • 31944434789 scopus 로고    scopus 로고
    • Evolution of a polyphenism by genetic accommodation
    • Suzuki Y, Nijhout HF. 2006. Evolution of a polyphenism by genetic accommodation. Science 311:650-52
    • (2006) Science , vol.311 , pp. 650-652
    • Suzuki, Y.1    Nijhout, H.F.2
  • 107
    • 62349105350 scopus 로고    scopus 로고
    • Congruent evolution of genetic and environmental robustness in micro-RNA
    • Szollosi GJ, Derenyi I. 2009. Congruent evolution of genetic and environmental robustness in micro-RNA. Mol. Biol. Evol. 26:867-74
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 867-874
    • Szollosi, G.J.1    Derenyi, I.2
  • 108
    • 77953916528 scopus 로고    scopus 로고
    • HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
    • Taipale M, Jarosz DF, Lindquist S. 2010. HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat. Rev. Mol. Cell Biol. 11:515-28
    • (2010) Nat. Rev. Mol. Cell Biol. , Issue.11 , pp. 515-528
    • Taipale, M.1    Jarosz, D.F.2    Lindquist, S.3
  • 109
    • 84874403980 scopus 로고    scopus 로고
    • Multiple capacitors for natural genetic variation in Drosophila melanogaster
    • Takahashi KH. 2013. Multiple capacitors for natural genetic variation in Drosophila melanogaster. Mol. Ecol. 22:1356-65
    • (2013) Mol. Ecol. , Issue.22 , pp. 1356-1365
    • Takahashi, K.H.1
  • 110
    • 79955558188 scopus 로고    scopus 로고
    • Environmental stress-dependent effects of deletions encompassing Hsp70Ba on canalization and quantitative trait asymmetry in Drosophila melanogaster
    • Takahashi KH, Daborn PJ, Hoffmann AA, Takano-Shimizu T. 2011a. Environmental stress-dependent effects of deletions encompassing Hsp70Ba on canalization and quantitative trait asymmetry in Drosophila melanogaster. PLOS ONE 6:e17295
    • (2011) PLOS ONE , vol.6 , pp. e17295
    • Takahashi, K.H.1    Daborn, P.J.2    Hoffmann, A.A.3    Takano-Shimizu, T.4
  • 111
    • 79959518707 scopus 로고    scopus 로고
    • Genome-wide deficiency mapping of the regions responsible for temporal canalization of the developmental processes of Drosophila melanogaster
    • Takahashi KH, Okada Y, Teramura K. 2011b. Genome-wide deficiency mapping of the regions responsible for temporal canalization of the developmental processes of Drosophila melanogaster. J. Hered. 102:448-57
    • (2011) J. Hered. , vol.102 , pp. 448-457
    • Takahashi, K.H.1    Okada, Y.2    Teramura, K.3
  • 112
    • 85027924055 scopus 로고    scopus 로고
    • Deficiency screening for genomic regions with effects on environmental sensitivity of the sensory bristles of Drosophila melanogaster
    • Takahashi KH, Okada Y, Teramura K. 2012. Deficiency screening for genomic regions with effects on environmental sensitivity of the sensory bristles of Drosophila melanogaster. Evolution 66:2878-90
    • (2012) Evolution , vol.66 , pp. 2878-2890
    • Takahashi, K.H.1    Okada, Y.2    Teramura, K.3
  • 113
  • 114
    • 78649829305 scopus 로고    scopus 로고
    • Chromatin regulators as capacitors of interspecies variations in gene expression
    • Tirosh I, Reikhav S, Sigal N, Assia Y, Barkai N. 2010. Chromatin regulators as capacitors of interspecies variations in gene expression. Mol. Syst. Biol. 6:435
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 435
    • Tirosh, I.1    Reikhav, S.2    Sigal, N.3    Assia, Y.4    Barkai, N.5
  • 116
    • 0034727077 scopus 로고    scopus 로고
    • A yeast prion provides a mechanism for genetic variation and phenotypic diversity
    • True HL, Lindquist SL. 2000. A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature 407:477-83
    • (2000) Nature , vol.407 , pp. 477-483
    • True, H.L.1    Lindquist, S.L.2
  • 117
    • 0035051264 scopus 로고    scopus 로고
    • Developmental system drift and flexibility in evolutionary trajectories
    • True JR, Haag ES. 2001. Developmental system drift and flexibility in evolutionary trajectories. Evol. Dev. 3:109-19
    • (2001) Evol. Dev. , vol.3 , pp. 109-119
    • True, J.R.1    Haag, E.S.2
  • 118
    • 34249819336 scopus 로고    scopus 로고
    • MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
    • Tsang J, Zhu J, vanOudenaarden A. 2007. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol. Cell 26:753-67
    • (2007) Mol. Cell , vol.26 , pp. 753-767
    • Tsang, J.1    Zhu, J.2    Van Oudenaarden, A.3
  • 120
    • 0034644270 scopus 로고    scopus 로고
    • The segment polarity network is a robust developmental module
    • vonDassowG,Meir E,Munro EM,Odell GM. 2000. The segment polarity network is a robust developmental module. Nature 406:188-92
    • (2000) Nature , vol.406 , pp. 188-192
    • Von Dassow, G.1    Meir, E.2    Munro, E.M.3    Odell, G.M.4
  • 121
    • 51149203927 scopus 로고
    • Canalization of development and the inheritance of acquired characters
    • Waddington CH. 1942. Canalization of development and the inheritance of acquired characters. Nature 150:563-65
    • (1942) Nature , vol.150 , pp. 563-565
    • Waddington, C.H.1
  • 122
    • 0001102269 scopus 로고
    • Genetic assimilation of an acquired character
    • Waddington CH. 1953. Genetic assimilation of an acquired character. Evolution 7:118-26
    • (1953) Evolution , vol.7 , pp. 118-126
    • Waddington, C.H.1
  • 125
    • 80052796317 scopus 로고    scopus 로고
    • The molecular origins of evolutionary innovations
    • Wagner A. 2011. The molecular origins of evolutionary innovations. Trends Genet. 27:397-410
    • (2011) Trends Genet. , vol.27 , pp. 397-410
    • Wagner, A.1
  • 126
    • 84857510399 scopus 로고    scopus 로고
    • The role of robustness in phenotypic adaptation and innovation
    • Wagner A. 2012. The role of robustness in phenotypic adaptation and innovation. Proc. Biol. Sci. 279:1249-58
    • (2012) Proc. Biol. Sci. , vol.279 , pp. 1249-1258
    • Wagner, A.1
  • 128
    • 0035913336 scopus 로고    scopus 로고
    • Evolution of digital organisms at high mutation rates leads to survival of the flattest
    • Wilke CO, Wang JL, Ofria C, Lenski RE, Adami C. 2001. Evolution of digital organisms at high mutation rates leads to survival of the flattest. Nature 412:331-33
    • (2001) Nature , vol.412 , pp. 331-333
    • Wilke, C.O.1    Wang, J.L.2    Ofria, C.3    Lenski, R.E.4    Adami, C.5
  • 129
    • 0031104842 scopus 로고    scopus 로고
    • Canalization: A molecular genetic perspective
    • Wilkins AS. 1997. Canalization: a molecular genetic perspective. Bioessays 19:257-62
    • (1997) Bioessays , vol.19 , pp. 257-262
    • Wilkins, A.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.