Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase

Metabolic Engineering

Volumn 27, Issue , 2015, Pages 65-75

  Ignea, Codruta ^a   Trikka, Fotini A ^b   Nikolaidis, Alexandros K ^b   Georgantea, Panagiota ^c   Ioannou, Efstathia ^c   Loupassaki, Sofia ^a   Kefalas, Panagiotis ^a   Kanellis, Angelos K ^d   Roussis, Vassilios ^c   Makris, Antonios M ^b   Kampranis, Sotirios C ^a,e  

^a MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA   (Greece)

^b INFORMATION TECHNOLOGIES INSTITUTE   (Greece)

^c UNIVERSITY OF ATHENS   (Greece)

^d ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^e UNIVERSITY OF CRETE   (Greece)

Author keywords

Geranylgeranyl diphosphate; Isoprenoid; Protein engineering; Terpene synthase; Yeast

Indexed keywords

ESSENTIAL OILS; GENETIC ENGINEERING; LIPIDS; OLEFINS; PRODUCTION PLATFORMS; PROTEINS; TERPENES;

BIOSYNTHETIC PATHWAY; FARNESYL DIPHOSPHATE SYNTHASE; GERANYLGERANYL DIPHOSPHATE; ISOPRENOIDS; MODULAR STRUCTURES; PROTEIN ENGINEERING; SESQUITERPENES; SYNTHASES;

YEAST;

ABIENOL; ABIETADIENE; BETA CAROTENE; DITERPENE; FARNESYL TRANS TRANSFERASE; GERANYLGERANYL PYROPHOSPHATE; ISOPRENOID; SCLAREOL; TERPENE; UNCLASSIFIED DRUG; DITERPENES; GERANYLTRANSTRANSFERASE; POLYISOPRENYL PHOSPHATES; SACCHAROMYCES CEREVISIAE PROTEINS;

ARTICLE; BIOSYNTHESIS; GENETIC ENGINEERING; NONHUMAN; PROTEIN ENGINEERING; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; YEAST; ENZYMOLOGY; GENETICS; METABOLIC ENGINEERING; METABOLISM;

DITERPENES; GERANYLTRANSTRANSFERASE; METABOLIC ENGINEERING; POLYISOPRENYL PHOSPHATES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84912120800     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.10.008     Document Type: Article

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