Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila

Neurobiology of Disease

Volumn 74, Issue , 2015, Pages 76-88

  Jäckel, Sandra ^a,b   Summerer, Anna K ^b   Thömmes, Catherine M ^b   Pan, Xia ^c   Voigt, Aaron ^c   Schulz, Jörg B ^c   Rasse, Tobias M ^b   Dormann, Dorothee ^d   Haass, Christian ^a,d   Kahle, Philipp J ^a,b  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

Author keywords

ALS; Caz; Drosophila; FTLD; FUS; PRMT; Transportin

Indexed keywords

ARGININE METHYLTRANSFERASE 1; CARRIER PROTEIN; FUSED IN SARCOMA PROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; TRANSPORTIN; UNCLASSIFIED DRUG; CABEZA PROTEIN, DROSOPHILA; DART1 PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; FUS PROTEIN, HUMAN; KARYOPHERIN; METHYLTRANSFERASE; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR IID; TRANSPORTIN PROTEIN, DROSOPHILA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; DROSOPHILA; MALE; MOTONEURON; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN TRANSPORT; ACTIVE TRANSPORT; ANIMAL; DEGENERATIVE DISEASE; DISEASE MODEL; DNA METHYLATION; DROSOPHILA MELANOGASTER; EYE; GENE SILENCING; GENETICS; HUMAN; METABOLISM; MOTOR DYSFUNCTION; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RNA INTERFERENCE; TRANSGENIC ANIMAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DNA METHYLATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE; GENE KNOCKDOWN TECHNIQUES; HUMANS; KARYOPHERINS; METHYLTRANSFERASES; MOTOR NEURONS; MOVEMENT DISORDERS; MUTATION; NEURODEGENERATIVE DISEASES; RNA INTERFERENCE; RNA-BINDING PROTEIN FUS; RNA-BINDING PROTEINS; TRANSCRIPTION FACTOR TFIID;

EID: 84912050990     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.11.003     Document Type: Article

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