An ALS-associated mutation in the FUS 3′2-UTR disrupts a microRNA-FUS regulatory circuitry

Nature Communications

Volumn 5, Issue , 2014, Pages

  Dini Modigliani, Stefano ^a   Morlando, Mariangela ^b   Errichelli, Lorenzo ^a,b   Sabatelli, Mario ^c   Bozzoni, Irene ^a,b,d  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 141; MICRORNA 200A; RNA BINDING PROTEIN; SMALL INTERFERING RNA; 3' UNTRANSLATED REGION; HOMEODOMAIN PROTEIN; MIRN141 MICRORNA, HUMAN; MIRN200 MICRORNA, HUMAN; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN;

DISEASE SEVERITY; FUNCTIONAL ROLE; GENE EXPRESSION; GENETIC ANALYSIS; HOMINID; MUTATION; NERVOUS SYSTEM DISORDER; NEUROLOGY; PATHOLOGY; PHYSIOLOGY; PROTEIN; RNA;

3' UNTRANSLATED REGION; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL CULTURE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE MUTATION; HUMAN; IN VITRO STUDY; INTRACELLULAR SPACE; LUCIFERASE ASSAY; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLASMID; POINT MUTATION; PROTEIN EXPRESSION; WESTERN BLOTTING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION;

3' UNTRANSLATED REGIONS; AMYOTROPHIC LATERAL SCLEROSIS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; MICRORNAS; MUTATION; RNA-BINDING PROTEIN FUS; TRANSCRIPTION FACTORS;

EID: 84904195219     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5335     Document Type: Article

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