-
1
-
-
77956850818
-
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
-
Mackenzie IR, Rademakers R, Neumann M (2010) TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 9: 995-1007
-
(2010)
Lancet Neurol
, vol.9
, pp. 995-1007
-
-
MacKenzie, I.R.1
Rademakers, R.2
Neumann, M.3
-
2
-
-
79960835044
-
Neuropathological background of phenotypical variability in frontotemporal dementia
-
Josephs KA, Hodges JR, Snowden JS, Mackenzie IR, Neumann M, Mann DM, Dickson DW (2011) Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 122: 137-153
-
(2011)
Acta Neuropathol
, vol.122
, pp. 137-153
-
-
Josephs, K.A.1
Hodges, J.R.2
Snowden, J.S.3
MacKenzie, I.R.4
Neumann, M.5
Mann, D.M.6
Dickson, D.W.7
-
3
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance C et al (2009) Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 323: 1208-1211
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
-
4
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski TJ Jr. et al (2009) Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 323: 1205-1208
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski Jr., T.J.1
-
5
-
-
82955236089
-
RNA targets of wild-type and mutant FET family proteins
-
Hoell JI et al (2011) RNA targets of wild-type and mutant FET family proteins. Nat Struct Mol Biol 18: 1428-1431
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1428-1431
-
-
Hoell, J.I.1
-
6
-
-
0344407006
-
Protooncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins
-
Meissner M, Lopato S, Gotzmann J, Sauermann G, Barta A (2003) Protooncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins. Exp Cell Res 283: 184-195
-
(2003)
Exp Cell Res
, vol.283
, pp. 184-195
-
-
Meissner, M.1
Lopato, S.2
Gotzmann, J.3
Sauermann, G.4
Barta, A.5
-
7
-
-
77955792022
-
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
-
Dormann D et al (2010) ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. EMBO J 29: 2841-2857
-
(2010)
EMBO J
, vol.29
, pp. 2841-2857
-
-
Dormann, D.1
-
8
-
-
0034605045
-
Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes
-
Takei Y, Teng J, Harada A, Hirokawa N (2000) Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes. J Cell Biol 150: 989-1000
-
(2000)
J Cell Biol
, vol.150
, pp. 989-1000
-
-
Takei, Y.1
Teng, J.2
Harada, A.3
Hirokawa, N.4
-
10
-
-
10944272640
-
Tau gene alternative splicing: Expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases
-
Andreadis A (2005) Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases. Biochim Biophys Acta 1739: 91-103
-
(2005)
Biochim Biophys Acta
, vol.1739
, pp. 91-103
-
-
Andreadis, A.1
-
11
-
-
0026729767
-
Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons
-
Chen J, Kanai Y, Cowan NJ, Hirokawa N (1992) Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature 360: 674-677
-
(1992)
Nature
, vol.360
, pp. 674-677
-
-
Chen, J.1
Kanai, Y.2
Cowan, N.J.3
Hirokawa, N.4
-
13
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M et al (1998) Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393: 702-705
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
-
14
-
-
49149083015
-
Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments
-
Brunden KR, Trojanowski JQ, Lee VM (2008) Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments. J Alzheimers Dis 14: 393-399
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 393-399
-
-
Brunden, K.R.1
Trojanowski, J.Q.2
Lee, V.M.3
-
15
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
de Calignon A, Fox LM, Pitstick R, Carlson GA, Bacskai BJ, Spires-Jones TL, Hyman BT (2010) Caspase activation precedes and leads to tangles. Nature 464: 1201-1204
-
(2010)
Nature
, vol.464
, pp. 1201-1204
-
-
De Calignon, A.1
Fox, L.M.2
Pitstick, R.3
Carlson, G.A.4
Bacskai, B.J.5
Spires-Jones, T.L.6
Hyman, B.T.7
-
16
-
-
48249102700
-
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: The GenePD Study
-
Tobin JE et al (2008) Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology 71: 28-34
-
(2008)
Neurology
, vol.71
, pp. 28-34
-
-
Tobin, J.E.1
-
17
-
-
33845361007
-
Haplotype-specific expression of exon 10 at the human MAPT locus
-
Caffrey TM, Joachim C, Paracchini S, Esiri MM, Wade-Martins R (2006) Haplotype-specific expression of exon 10 at the human MAPT locus. Hum Mol Genet 15: 3529-3537
-
(2006)
Hum Mol Genet
, vol.15
, pp. 3529-3537
-
-
Caffrey, T.M.1
Joachim, C.2
Paracchini, S.3
Esiri, M.M.4
Wade-Martins, R.5
-
18
-
-
79953185674
-
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
-
Polymenidou M et al (2011) Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nat Neurosci 14: 459-468
-
(2011)
Nat Neurosci
, vol.14
, pp. 459-468
-
-
Polymenidou, M.1
-
19
-
-
75649135319
-
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
-
Fiesel FC et al (2010) Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J 29: 209-221
-
(2010)
EMBO J
, vol.29
, pp. 209-221
-
-
Fiesel, F.C.1
-
20
-
-
0029835019
-
A spatial gradient of tau protein phosphorylation in nascent axons
-
Mandell JW, Banker GA (1996) A spatial gradient of tau protein phosphorylation in nascent axons. J Neurosci 16: 5727-5740
-
(1996)
J Neurosci
, vol.16
, pp. 5727-5740
-
-
Mandell, J.W.1
Banker, G.A.2
-
21
-
-
70350641659
-
The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort
-
Williams-Gray CH et al (2009) The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort. Brain 132: 2958-2969
-
(2009)
Brain
, vol.132
, pp. 2958-2969
-
-
Williams-Gray, C.H.1
-
22
-
-
53149130215
-
Neuronal gene expression correlates of Parkinson's disease with dementia
-
Stamper C et al (2008) Neuronal gene expression correlates of Parkinson's disease with dementia. Mov Disord 23: 1588-1595
-
(2008)
Mov Disord
, vol.23
, pp. 1588-1595
-
-
Stamper, C.1
-
23
-
-
33847406346
-
Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia
-
Sundar PD et al (2007) Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia. Hum Mol Genet 16: 295-306
-
(2007)
Hum Mol Genet
, vol.16
, pp. 295-306
-
-
Sundar, P.D.1
-
24
-
-
15744378126
-
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology
-
Fujii R, Okabe S, Urushido T, Inoue K, Yoshimura A, Tachibana T, Nishikawa T, Hicks GG, Takumi T (2005) The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. Curr Biol 15: 587-593
-
(2005)
Curr Biol
, vol.15
, pp. 587-593
-
-
Fujii, R.1
Okabe, S.2
Urushido, T.3
Inoue, K.4
Yoshimura, A.5
Tachibana, T.6
Nishikawa, T.7
Hicks, G.G.8
Takumi, T.9
-
25
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
Ittner LM et al (2010) Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell 142: 387-397
-
(2010)
Cell
, vol.142
, pp. 387-397
-
-
Ittner, L.M.1
-
26
-
-
75949101467
-
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132
-
Edbauer D et al (2010) Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron 65: 373-384
-
(2010)
Neuron
, vol.65
, pp. 373-384
-
-
Edbauer, D.1
-
27
-
-
34548864370
-
Culturing hippocampal neurons
-
Kaech S, Banker G (2006) Culturing hippocampal neurons. Nat Protoc 1: 2406-2415
-
(2006)
Nat Protoc
, vol.1
, pp. 2406-2415
-
-
Kaech, S.1
Banker, G.2
|