FUS-NLS/Transportin 1 Complex Structure Provides Insights into the Nuclear Targeting Mechanism of FUS and the Implications in ALS

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Niu, Chunyan ^a   Zhang, Jiayu ^b   Gao, Feng ^a   Yang, Liuqing ^b   Jia, Minze ^a   Zhu, Haining ^b   Gong, Weimin ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; FUSED IN SARCOMA PROTEIN; MUTANT PROTEIN; TRANSPORTIN 1; UNCLASSIFIED DRUG;

ALPHA HELIX; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOLOGY; DISEASE ASSOCIATION; DISEASE DURATION; DNA RNA HYBRIDIZATION; GENE MUTATION; HUMAN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PATHOGENESIS; PROTEIN DNA INTERACTION; PROTEIN FOLDING; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; BETA KARYOPHERINS; HUMANS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RNA-BINDING PROTEIN FUS; SEQUENCE HOMOLOGY, AMINO ACID; SURFACE PLASMON RESONANCE;

EID: 84867290759     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047056     Document Type: Article

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