Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations

Acta Neuropathologica

Volumn 124, Issue 5, 2012, Pages 705-716

  Neumann, Manuela ^a,b   Valori, Chiara F ^a   Ansorge, Olaf ^c   Kretzschmar, Hans A ^d   Munoz, David G ^e   Kusaka, Hirofumi ^f   Yokota, Osamu ^g   Ishihara, Kenji ^h   Ang, Lee Cyn ⁱ   Bilbao, Juan M ^j   MacKenzie, Ian R A ^k  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF MUNICH   (Germany)

^e ST MICHAEL'S HOSPITAL   (Canada)

^f KANSAI MEDICAL UNIVERSITY   (Japan)

^g OKAYAMA UNIVERSITY   (Japan)

^h SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ LONDON HEALTH SCIENCES CENTRE   (Canada)

^j SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^k UNIVERSITY OF BRITISH COLUMBIA   (Canada)

more..

Author keywords

Amyotrophic lateral sclerosis; EWS; Frontotemporal dementia; FUS; TAF15; Transportin

Indexed keywords

CARRIER PROTEIN; DNA BINDING PROTEIN; FET PROTEIN; FUSED IN SARCOMA PROTEIN; HEXIM1 PROTEIN; HNRNP A0 PROTEIN; HNRNP A1 PROTEIN; HNRNP A2 PROTEIN; HNRNP B1 PROTEIN; HNRNP D PROTEIN; HNRNP M3 PROTEIN; HNRNP M4 PROTEIN; HUR PROTEIN; ISOPROTEIN; PABPN1 PROTEIN; PBQP 1 PROTEIN; PROTEIN SAM68; RBM39 PROTEIN; RNA BINDING PROTEIN; SLM 2 PROTEIN; TATA BINDING PROTEIN RELATED FACTOR 15; TRANSPORTIN 1; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BIOCHEMISTRY; BRAIN CORTEX; CELL INCLUSION; CLINICAL ARTICLE; CONTROLLED STUDY; EWING SARCOMA; FRONTOTEMPORAL DEMENTIA; FUS GENE; GENE MUTATION; GENETIC ASSOCIATION; GLIA CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NERVE CELL; NEUROPATHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SPINAL CORD; SUBCORTEX; TAUOPATHY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMYOTROPHIC LATERAL SCLEROSIS; BETA KARYOPHERINS; BRAIN; DNA-BINDING PROTEINS; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; GENE EXPRESSION REGULATION; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; INCLUSION BODIES; MALE; MUTATION; POLY(A)-BINDING PROTEIN I; RNA-BINDING PROTEIN EWS; RNA-BINDING PROTEIN FUS; RNA-BINDING PROTEINS; TATA-BINDING PROTEIN ASSOCIATED FACTORS;

EID: 84871019907     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-1020-6     Document Type: Article

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