Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation

FASEB Journal

Volumn 28, Issue 11, 2014, Pages 4914-4923

  Manni, Sandro ^a   Kisko, Kaisa ^a   Schleier, Thomas ^a   Missimer, Jack ^a   Ballmer Hofer, Kurt ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

Activation; Phosphorylation; SAXS; Tyrosine kinase receptor

Indexed keywords

LIGAND; PHOSPHOTRANSFERASE; RECOMBINANT PROTEIN; VASCULOTROPIN RECEPTOR 2; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2, HUMAN;

ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; DISSOCIATION CONSTANT; EMBRYO; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; GEL PERMEATION CHROMATOGRAPHY; GENE MUTATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYDRODYNAMICS; INSECT CELL; KINASE INSERT DOMAIN; LIGAND BINDING; LIGHT SCATTERING; MOLECULAR WEIGHT; NONHUMAN; PROTEIN DOMAIN; RECEPTOR BINDING; SEDIMENTATION; SIGNAL TRANSDUCTION; ULTRACENTRIFUGATION; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; ENDOTHELIUM CELL; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84912044850     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-256206     Document Type: Article

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