Kinase Insert Domain Receptor (KDR) Extracellular Immunoglobulin-like Domains 4-7 Contain Structural Features That Block Receptor Dimerization and Vascular Endothelial Growth Factor-induced Signaling

Journal of Biological Chemistry

Volumn 276, Issue 24, 2001, Pages 21916-21923

  Tao, Qi ^a   Backer, Marina V ^b   Backer, Joseph M ^b   Terman, Bruce I ^a,c  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b SIBTECH INC   (United States)

^c Cardiology Division   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; CELLS; ENZYME KINETICS; GROWTH KINETICS; IMMUNOLOGY; MUTAGENESIS; PROTEINS;

CELL DEATH; MUTANT RECEPTORS;

BIOCHEMISTRY;

NEUROPILIN 1; PROTEOHEPARAN SULFATE; RECEPTOR ANTIBODY; RECEPTOR PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR TYROSINE KINASE SUBTYPE KINASE INSERT DOMAIN RECEPTOR; VASCULOTROPIN; ENDOTHELIAL CELL GROWTH FACTOR; GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN; ISOENZYME; LYMPHOKINE; NCK PROTEIN; ONCOPROTEIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PROTEIN TYROSINE KINASE; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; BINDING SITE; CELL SURFACE; CONTROLLED STUDY; DIMERIZATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN LIKE DOMAIN; IMMUNOGLOBULIN LIKE DOMAIN 4-6; IMMUNOGLOBULIN LIKE DOMAIN 4-7; IMMUNOGLOBULIN LIKE DOMAIN 7; KINASE INSERT DOMAIN RECEPTOR EXTRACELLULAR IMMUNOGLOBULIN LIKE DOMAIN 4-7; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; AORTA; CELL CULTURE; CELL LINE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; GENETIC TRANSFECTION; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RADIOASSAY; SWINE; VASCULAR ENDOTHELIUM;

ANIMALIA; SUIDAE;

ANIMALS; AORTA; BINDING SITES; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; DIMERIZATION; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; IMMUNOGLOBULINS; ISOENZYMES; KINETICS; LYMPHOKINES; ONCOGENE PROTEINS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; RADIOLIGAND ASSAY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT PROTEINS; SWINE; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035877708     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100763200     Document Type: Article

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