The single transmembrane domains of human receptor tyrosine kinases encode self-interactions

Science Signaling

Volumn 2, Issue 89, 2009, Pages

  Finger, Carmen ^a   Escher, Claudia ^a   Schneider, Dirk ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; HYBRID PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL MEMBRANE; CONTROLLED STUDY; DIMERIZATION; ENZYME STRUCTURE; HUMAN; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; BINDING SITE; BIOLOGICAL MODEL; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; ESCHERICHIA COLI; GENETICS; IN VITRO STUDY; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CELL MEMBRANE; DIMERIZATION; ESCHERICHIA COLI; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 73349087177     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2000547     Document Type: Article

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69. We thank D. M. Engelman for providing the TOXCAT system. This work was supported by a grant from the Deutsche Forschungsgemeinschaft (SCHN 690/2-3). Financial support from the Ministry of Science, Research, and Arts of Baden-Württemberg is also gratefully acknowledged. C.F. is supported by a Schlieben-Lange fellowship of the Ministry of Science, Research, and Arts of Baden-Württemberg. We thank E. Salfelder for technical support.