Structural analysis of vascular endothelial growth factor receptor-2/ligand complexes by small-angle X-ray solution scattering

FASEB Journal

Volumn 25, Issue 9, 2011, Pages 2980-2986

  Kisko, Kaisa ^a   Brozzo, Maurice S ^a   Missimer, John ^a   Schleier, Thomas ^a   Menzel, Andreas ^a   Leppan̈en, Veli Matti ^b   Alitalo, Kari ^b   Walzthoeni, Thomas ^c,d   Aebersold, Ruedi ^c,d   Ballmer Hofer, Kurt ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c ETH ZURICH   (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cross linking; Mass spectrometry; Receptor tyrosine kinase; SAXS; VEGF

Indexed keywords

IMMUNOGLOBULIN; LIGAND; PROTEIN TYROSINE KINASE; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BINDING SITE; CELLS AND CELL COMPONENTS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTALLIZATION; EXTRACELLULAR DOMAIN; INTRACELLULAR DOMAIN; LIGAND BINDING; LYMPH VESSEL; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN PURIFICATION; RECEPTOR BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; LIGANDS; MASS SPECTROMETRY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; X-RAY DIFFRACTION;

EID: 80052675879     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-185397     Document Type: Article

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