In Vitro and In Vivo Characterization of Two C-11-Labeled PET Tracers for Vesicular Acetylcholine Transporter

Molecular Imaging and Biology

Volumn 16, Issue 6, 2014, Pages 773-780

  Padakanti, Prashanth K ^a   Zhang, Xiang ^a   Jin, Hongjun ^a   Cui, Jinquan ^a   Wang, Ruike ^a   Li, Junfeng ^a   Flores, Hubert P ^a   Parsons, Stanley M ^b   Perlmutter, Joel S ^a   Tu, Zhude ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer s disease; PET imaging; Radiotracer; VAChT; Vesamicol

Indexed keywords

ACETYLCHOLINESTERASE; BIOLOGICAL MARKER; CARBON 11; HALOPERIDOL; RADIOLIGAND; SIGMA OPIATE RECEPTOR; TRACER; VESAMICOL; VESICULAR ACETYLCHOLINE TRANSPORTER; CARBON; RADIOPHARMACEUTICAL AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BLOOD BRAIN BARRIER; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ACCUMULATION; DRUG METABOLISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG UPTAKE; ENANTIOMER; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MACACA FASCICULARIS; MALE; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MOLECULAR STABILITY; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DISTRIBUTION; RAT; RECEPTOR BINDING; RECEPTOR BINDING ASSAY; ANIMAL; BRAIN; BRAIN CHEMISTRY; CHEMISTRY; METABOLISM; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ANIMALS; AUTORADIOGRAPHY; BRAIN; BRAIN CHEMISTRY; CARBON ISOTOPES; MACACA FASCICULARIS; MALE; RADIOACTIVE TRACERS; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 84911976960     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-014-0749-9     Document Type: Article

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