In vivo imaging of human cholinergic nerve terminals with (-)-5- 18F-fluoroethoxybenzovesamicol: Biodistribution, dosimetry, and tracer kinetic analyses

Journal of Nuclear Medicine

Volumn 55, Issue 3, 2014, Pages 396-404

  Petrou, Myria ^a   Frey, Kirk A ^a   Kilbourn, Michael R ^a   Scott, Peter J H ^a   Raffel, David M ^a   Bohnen, Nicolaas I ^a,b   Müller, Martijn L T M ^a   Albin, Roger L ^a,b   Koeppe, Robert A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VAAAHS   (United States)

Author keywords

Dementia; PET; VAChT

Indexed keywords

FLUOROETHOXYBENZOVESAMICOL F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VESICULAR ACETYLCHOLINE TRANSPORTER; DIAGNOSTIC AGENT; FLUOROETHOXY BENZOVESAMICOL; FLUOROETHOXY-BENZOVESAMICOL; PIPERIDINE DERIVATIVE; TRACER;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; BOLUS INJECTION; CEREBELLUM; CHOLINERGIC NERVE; CHROMATOGRAPHY; CONTROLLED STUDY; CORPUS STRIATUM; DOSIMETRY; DRUG DISTRIBUTION; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; MALE; MOTOR CORTEX; NORMAL HUMAN; PET SCANNER; PRIORITY JOURNAL; RADIATION DOSE; THALAMUS; TISSUE DISTRIBUTION; 18F-FEOBV; ADOLESCENT; BRAIN; CHOLINERGIC NERVE CELL; CLINICAL TRIAL; CYTOLOGY; DEMENTIA; KINETICS; METABOLISM; METHODOLOGY; MIDDLE AGED; PET; POSITRON EMISSION TOMOGRAPHY; RADIOMETRY; SAFETY; SCINTISCANNING; YOUNG ADULT;

18F-FEOBV; DEMENTIA; PET; VACHT;

ADOLESCENT; ADULT; AGED; BRAIN; CHOLINERGIC NEURONS; FEMALE; HUMANS; KINETICS; MALE; MIDDLE AGED; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RADIOMETRY; SAFETY; TISSUE DISTRIBUTION; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS; YOUNG ADULT;

EID: 84899490091     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.124792     Document Type: Article

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