메뉴 건너뛰기




Volumn 25, Issue 4, 1997, Pages 368-380

Imaging of cholinergic terminals using the radiotracer [18F](+)-4- fluorobenzyltrozamicol: In vitro binding studies and positron emission tomography studies in nonhuman primates

Author keywords

cholinergic terminals; positron emission tomography; rhesus monkey; vesamicol receptor

Indexed keywords

4 FLUOROBENZYLTROZAMICOL; ACETYLCHOLINE; FLUORINE 18; TRACER; UNCLASSIFIED DRUG; VESAMICOL;

EID: 0031002932     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199704)25:4<368::AID-SYN8>3.0.CO;2-8     Document Type: Article
Times cited : (54)

References (67)
  • 1
    • 0023820380 scopus 로고
    • 3H]vesamicol binding in brain: Autoradiographic distribution, pharmacology, and effects of cholinergic lesions
    • 3H]vesamicol binding in brain: Autoradiographic distribution, pharmacology, and effects of cholinergic lesions. Synapse, 2:486-493.
    • (1988) Synapse , vol.2 , pp. 486-493
    • Altar, C.A.1    Marien, M.R.2
  • 2
    • 0028984349 scopus 로고
    • L-DOPA is converted in serotonergic fibers of the striatum of the rat: A double-labelingimmunofluorescence study
    • Arai, R., Karasawa, N., Geffard, M., and Nagatsu, I. (1995) L-DOPA is converted in serotonergic fibers of the striatum of the rat: A double-labelingimmunofluorescence study. Neurosci. Lett., 195:195-198.
    • (1995) Neurosci. Lett. , vol.195 , pp. 195-198
    • Arai, R.1    Karasawa, N.2    Geffard, M.3    Nagatsu, I.4
  • 3
    • 0026501148 scopus 로고
    • Comparative alterations of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases
    • Aubert, I., Araujo, D.M., Cecyre, D., Robitaille, Y., Gauthier, S., and Quirion, R. (1992) Comparative alterations of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases. J. Neurochem., 58:529-541.
    • (1992) J. Neurochem. , vol.58 , pp. 529-541
    • Aubert, I.1    Araujo, D.M.2    Cecyre, D.3    Robitaille, Y.4    Gauthier, S.5    Quirion, R.6
  • 4
    • 0017091532 scopus 로고
    • Short-term memory in the rhesus monkey: Disruption from the anti-cholinergic scopolamine
    • Bartus, R.T., and Johnson, H.R. (1976) Short-term memory in the rhesus monkey: Disruption from the anti-cholinergic scopolamine. Pharmacol. Biochem. Behav., 5:39-46.
    • (1976) Pharmacol. Biochem. Behav. , vol.5 , pp. 39-46
    • Bartus, R.T.1    Johnson, H.R.2
  • 5
    • 0017133142 scopus 로고
    • Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies
    • Bowen, D.M., Smith, C.B., White, P., and Davison, A.N. (1976) Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain, 99:459-496.
    • (1976) Brain , vol.99 , pp. 459-496
    • Bowen, D.M.1    Smith, C.B.2    White, P.3    Davison, A.N.4
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0023161657 scopus 로고
    • A receptors in Alzheimer's disease: A quantitative autoradiographic study
    • A receptors in Alzheimer's disease: A quantitative autoradiographic study. Neurology, 37:1454-1459.
    • (1987) Neurology , vol.37 , pp. 1454-1459
    • Chu, D.C.M.1    Penney, J.B.2    Young, A.B.3
  • 11
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies, P., and Maloney, A.J.F. (1976) Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet, 2:1403.
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.J.F.2
  • 12
    • 0023265074 scopus 로고
    • The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system
    • Decker, M.W. (1987) The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain Res. Rev., 12:424-438.
    • (1987) Brain Res. Rev. , vol.12 , pp. 424-438
    • Decker, M.W.1
  • 13
    • 0028875356 scopus 로고
    • Carbon-11-d-threo-Methylphenidate binding to dopamine transporter in baboon brain
    • Ding, Y.-S., Fowler, J.S., Volkow, N.D., Logan, J., Gatley, S.J., and Sugano, Y. (1995) Carbon-11-d-threo-Methylphenidate binding to dopamine transporter in baboon brain. J. Nucl. Med., 36:2298-2305.
    • (1995) J. Nucl. Med. , vol.36 , pp. 2298-2305
    • Ding, Y.-S.1    Fowler, J.S.2    Volkow, N.D.3    Logan, J.4    Gatley, S.J.5    Sugano, Y.6
  • 14
    • 0017652462 scopus 로고
    • Memory and cognitive function in man: Does the cholinergic system have a specific role?
    • Drachman, D.A. (1977) Memory and cognitive function in man: Does the cholinergic system have a specific role? Neurology, 27:783-790.
    • (1977) Neurology , vol.27 , pp. 783-790
    • Drachman, D.A.1
  • 15
    • 0015965912 scopus 로고
    • Human memory and the cholinergic system. A relationship to aging?
    • Drachman, D.A., and Leavitt, J. (1974) Human memory and the cholinergic system. A relationship to aging? Arch. Neurol., 30:113-121.
    • (1974) Arch. Neurol. , vol.30 , pp. 113-121
    • Drachman, D.A.1    Leavitt, J.2
  • 23
    • 0002037940 scopus 로고
    • Cholinergic systems and related neuropathological predilection patterns in Alzheimer disease
    • R.D. Terry, R. Katzman, and K.L. Bick, eds. Raven Press, New York
    • Geula, C., and Mesulam, M.-M. (1994) Cholinergic systems and related neuropathological predilection patterns in Alzheimer disease. In: Alzheimer Disease. R.D. Terry, R. Katzman, and K.L. Bick, eds. Raven Press, New York, pp. 263-291.
    • (1994) Alzheimer Disease , pp. 263-291
    • Geula, C.1    Mesulam, M.-M.2
  • 27
    • 0001247533 scopus 로고
    • PET radioligands for vesicular neurotransmitter transporters
    • Kilbourn, M.R. (1995) PET radioligands for vesicular neurotransmitter transporters. Med. Chem. Res., 5:113-126.
    • (1995) Med. Chem. Res. , vol.5 , pp. 113-126
    • Kilbourn, M.R.1
  • 30
    • 0026675620 scopus 로고
    • Neuroreceptor quantitation in vivo by the steady-state principle using constant infusion or bolus injection of radioactive tracers
    • Lassen, N.A. (1992) Neuroreceptor quantitation in vivo by the steady-state principle using constant infusion or bolus injection of radioactive tracers. J. Cereb. Blood Flow Metab., 12:709-716.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 709-716
    • Lassen, N.A.1
  • 32
    • 0025123674 scopus 로고
    • Cholinergic-dopaminergic interactions in cognitive performance
    • Levin, E.D., McGurk, S.R., Rose, J.E., and Butcher, L.L. (1990) Cholinergic-dopaminergic interactions in cognitive performance. Behav. Neural Biol., 54:271-299.
    • (1990) Behav. Neural Biol. , vol.54 , pp. 271-299
    • Levin, E.D.1    McGurk, S.R.2    Rose, J.E.3    Butcher, L.L.4
  • 37
    • 0021962590 scopus 로고
    • 2 muscarinic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation
    • 2 muscarinic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation. Science, 228:1115-1117.
    • (1985) Science , vol.228 , pp. 1115-1117
    • Mash, D.C.1    Flynn, D.D.2    Potter, L.T.3
  • 39
    • 0028593475 scopus 로고
    • In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog
    • Namba, H., Irie, T., Fukushi, K., and Iyo, M. (1994) In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog. Brain Res., 667:278-282.
    • (1994) Brain Res. , vol.667 , pp. 278-282
    • Namba, H.1    Irie, T.2    Fukushi, K.3    Iyo, M.4
  • 40
    • 77957230582 scopus 로고
    • In vivo diagnostics for Alzheimer's disease based on the acetylcholine transporter
    • Parsons, S.M., and Rogers, G. (1993) In vivo diagnostics for Alzheimer's disease based on the acetylcholine transporter. Ann. Reports Med. Chem., 28:247-255.
    • (1993) Ann. Reports Med. Chem. , vol.28 , pp. 247-255
    • Parsons, S.M.1    Rogers, G.2
  • 43
    • 0021059767 scopus 로고
    • Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase
    • Pearson, R.C.A., Sofroniew, M.V., Cuello, A.C., Powell, T.P.S., Eckenstein, F., Esiri, M.M., and Wilcock, G.K. (1983) Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase. Brain Res., 289:375-379.
    • (1983) Brain Res. , vol.289 , pp. 375-379
    • Pearson, R.C.A.1    Sofroniew, M.V.2    Cuello, A.C.3    Powell, T.P.S.4    Eckenstein, F.5    Esiri, M.M.6    Wilcock, G.K.7
  • 46
    • 0020284775 scopus 로고
    • Extensive loss of choline acetyltransferase is not reflected by neuronal loss in the nucleus of Meynert in Alzheimer's disease
    • Perry, R.H., Candy, J.M., Perry, E.K., Irving, D., Blessed, G., Fairbairn, A.F., and Tomlinson, B.E. (1982) Extensive loss of choline acetyltransferase is not reflected by neuronal loss in the nucleus of Meynert in Alzheimer's disease. Neurosci. Lett., 33:311-315.
    • (1982) Neurosci. Lett. , vol.33 , pp. 311-315
    • Perry, R.H.1    Candy, J.M.2    Perry, E.K.3    Irving, D.4    Blessed, G.5    Fairbairn, A.F.6    Tomlinson, B.E.7
  • 47
    • 0041561438 scopus 로고
    • Characterization and autoradiographic distribution of hemicholium-3 high-affinity choline uptake sites in mammalian brain
    • Quirion, R. (1987) Characterization and autoradiographic distribution of hemicholium-3 high-affinity choline uptake sites in mammalian brain. Synapse, 1:293-303.
    • (1987) Synapse , vol.1 , pp. 293-303
    • Quirion, R.1
  • 50
    • 84886617908 scopus 로고
    • Pre- and postsynaptic neurochemical alterations in Alzheimer's disease
    • Reisine, T.D., Yamamura, H.I., Bird, E.D., Spokes, E., and Enna, S.J. (1978) Pre-and postsynaptic neurochemical alterations in Alzheimer's disease. Brain Res., 159:477-481.
    • (1978) Brain Res. , vol.159 , pp. 477-481
    • Reisine, T.D.1    Yamamura, H.I.2    Bird, E.D.3    Spokes, E.4    Enna, S.J.5
  • 53
    • 0024328329 scopus 로고
    • Synthesis, in vitro acetylcholine-storage-blocking activities, and biological properties of derivatives and analogues of trans-2-(4-phenylpiperidino)cyclohexanol (vesamicol)
    • Rogers, G.A., Parsons, S.M., Anderson, D.C., Nilsson, B.A., Bahr, W.D., Kornreich, R., Kaufman, R., Jacobs, R.S., and Kirtman, B. (1989) Synthesis, in vitro acetylcholine-storage-blocking activities, and biological properties of derivatives and analogues of trans-2-(4-phenylpiperidino)cyclohexanol (vesamicol). J. Med. Chem., 32:1217-1230.
    • (1989) J. Med. Chem. , vol.32 , pp. 1217-1230
    • Rogers, G.A.1    Parsons, S.M.2    Anderson, D.C.3    Nilsson, B.A.4    Bahr, W.D.5    Kornreich, R.6    Kaufman, R.7    Jacobs, R.S.8    Kirtman, B.9
  • 54
    • 0027323936 scopus 로고
    • Kinetic and equilibrium characterization of vesamicol ligand complexes with picomolar dissociation constants
    • Rogers, G.A., Kornreich, W.D., Hand, K., and Parsons, S.M. (1993) Kinetic and equilibrium characterization of vesamicol ligand complexes with picomolar dissociation constants. Mol. Pharmacol., 44:633-641.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 633-641
    • Rogers, G.A.1    Kornreich, W.D.2    Hand, K.3    Parsons, S.M.4
  • 55
    • 0023005998 scopus 로고
    • Post-mortem neurochemical changes in Alzheimer's disease compared with normal ageing
    • Rossor, M., and Mountjoy, C.Q. (1986) Post-mortem neurochemical changes in Alzheimer's disease compared with normal ageing. Can. J. Neurol. Sci., 13:499-502.
    • (1986) Can. J. Neurol. Sci. , vol.13 , pp. 499-502
    • Rossor, M.1    Mountjoy, C.Q.2
  • 56
    • 0025288472 scopus 로고
    • 3H] vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions
    • 3H] vesamicol binding in the temporal cortex of patients with Alzheimer's disease, Parkinson's disease, and rats with basal forebrain lesions. Neuroscience, 35:327-333.
    • (1990) Neuroscience , vol.35 , pp. 327-333
    • Ruberg, M.1    Mayo, W.2    Brice, A.3    Duyckaetrs, C.4    Hauw, J.J.5    Simon, H.6    LeMoal, M.7    Agid, Y.8
  • 57
    • 0026004171 scopus 로고
    • Induction of cognitive impairment by scopolamine and non-cholinergic agents in rhesus monkeys
    • Rupniak, N.M.J., Samson, N.A., Steventon, M.J., and Iversen, S.D. (1991) Induction of cognitive impairment by scopolamine and non-cholinergic agents in rhesus monkeys. Life Sci., 48:893-899.
    • (1991) Life Sci. , vol.48 , pp. 893-899
    • Rupniak, N.M.J.1    Samson, N.A.2    Steventon, M.J.3    Iversen, S.D.4
  • 58
    • 0000372083 scopus 로고    scopus 로고
    • 5-hydroxytryptamine (serotonin) receptor agonists and antagonists
    • J.G. Hardman and L.E. Limbird, eds. McGraw-Hill, New York
    • Sanders-Bush, E., and Mayer, S.E. (1996) 5-hydroxytryptamine (serotonin) receptor agonists and antagonists. In: Goodman & Gilman's Pharmacological Basis of Therapeutics, 9th ed. J.G. Hardman and L.E. Limbird, eds. McGraw-Hill, New York, pp. 249-263.
    • (1996) Goodman & Gilman's Pharmacological Basis of Therapeutics, 9th Ed. , pp. 249-263
    • Sanders-Bush, E.1    Mayer, S.E.2
  • 61
    • 0025607117 scopus 로고
    • Nicotinic acetylcholine receptor subtypes in human frontal cortex: Changes in Alzheimer's disease
    • Sugaya, K., Giacobini, E., and Chiappinelli, V.A. (1990) Nicotinic acetylcholine receptor subtypes in human frontal cortex: Changes in Alzheimer's disease. J. Neurosci. Res., 27:349-359.
    • (1990) J. Neurosci. Res. , vol.27 , pp. 349-359
    • Sugaya, K.1    Giacobini, E.2    Chiappinelli, V.A.3
  • 63
    • 0029056219 scopus 로고
    • Regional distribution of mono-amine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: A postmortem study using tritiated tetrabenazine
    • Thibaut, F., Faucheux, B.A., Marquez, J., Villares, J., Menard, J.F., Agid, Y., and Hirsch, B.C. (1995) Regional distribution of mono-amine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: A postmortem study using tritiated tetrabenazine. Brain Res., 692:233-243.
    • (1995) Brain Res. , vol.692 , pp. 233-243
    • Thibaut, F.1    Faucheux, B.A.2    Marquez, J.3    Villares, J.4    Menard, J.F.5    Agid, Y.6    Hirsch, B.C.7
  • 64
    • 0025942345 scopus 로고
    • A, muscatinic, and β adrenoceptors and neuron degeneration in cingulate cortex in Alzheimer's disease
    • A, muscatinic, and β adrenoceptors and neuron degeneration in cingulate cortex in Alzheimer's disease. J. Neurochem., 57:282-290.
    • (1991) J. Neurochem. , vol.57 , pp. 282-290
    • Vogt, B.A.1    Crino, P.B.2    Volicer, L.3
  • 65
    • 0028195078 scopus 로고
    • Cloning and expression of the vesamicol binding protein from the marine ray Torpedo. Homology with the putative vesicular acetylcholine transporter UNC-17 from Caenorhabditis elegans
    • Varoqui, H., Diebler, M.-F., Meunier, F.-M., Rand, J.B., Usdin, T.B., Bonner, T.I., Eiden, L.E., and Erickson, J.D. (1994) Cloning and expression of the vesamicol binding protein from the marine ray Torpedo. Homology with the putative vesicular acetylcholine transporter UNC-17 from Caenorhabditis elegans. FEBS Lett., 342:97-102.
    • (1994) FEBS Lett. , vol.342 , pp. 97-102
    • Varoqui, H.1    Diebler, M.-F.2    Meunier, F.-M.3    Rand, J.B.4    Usdin, T.B.5    Bonner, T.I.6    Eiden, L.E.7    Erickson, J.D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.