Synthesis and binding affinities of methylvesamicol analogs for the acetylcholine transporter and sigma receptor

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 8, 2006, Pages 2620-2626

  Shiba, Kazuhiro ^a   Ogawa, Kazuma ^a   Ishiwata, Kiichi ^b   Yajima, Kazuyoshi ^c   Mori, Hirofumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c Medical and Pharmacological Research Center Foundation   (Japan)

Author keywords

Acetylcholine transporter; Sigma receptor; Vesamicol analogs

Indexed keywords

1 (3,4 DIMETHOXYPHENETHYL) 4 (3 PHENYLPROPYL)PIPERAZINE; 2 METHYLVESAMICOL; 2 TRIMETHYLSTANNYLVESAMICOL; 4 METHYLVESAMICOL; 4 TRIBUTYLSTANNYLVESAMICOL; CHOLINERGIC RECEPTOR; HALOPERIDOL; PENTAZOCINE; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG; VESAMICOL DERIVATIVE;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; LIGAND BINDING; POSITRON EMISSION TOMOGRAPHY; RECEPTOR AFFINITY;

ANIMALS; BRAIN; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PIPERIDINES; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SIGMA; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

OAT MOSAIC VIRUS; PAPAYA MOSAIC VIRUS;

EID: 33644785824     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.11.044     Document Type: Article

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