Structural re-arrangement and peroxidase activation of cytochrome c by anionic analogues of vitamin E, tocopherol succinate and tocopherol phosphate

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32488-32498

  Yanamala, Naveena ^a   Kapralov, Alexander A ^a   Djukic, Mirjana ^a   Peterson, Jim ^a   Mao, Gaowei ^a   Klein Seetharaman, Judith ^c   Stoyanovsky, Detcho A ^a   Stursa, Jan ^d   Neuzil, Jiri ^e,f   Kagan, Valerian E ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

^e INSTITUTE OF BIOTECHNOLOGY   (Czech Republic)

^f GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION SPECTROSCOPY; CELL DEATH; CHEMICAL ACTIVATION; ENZYME ACTIVITY; FATTY ACIDS; HYDROPHOBICITY; MITOCHONDRIA; PHOSPHOLIPIDS;

COMPUTATIONAL MODEL; ELECTRON SHUTTLING; HYDROPHOBIC CHAINS; INTERMEMBRANE SPACE; PEROXIDASE ACTIVITIES; PHARMACOLOGICAL ACTIVITY; RAT LIVER MITOCHONDRIA; RESPIRATORY COMPLEX;

C (PROGRAMMING LANGUAGE);

ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHEROL PHOSPHATE; ALPHA TOCOPHEROL SUCCINATE; CYTOCHROME C; PEROXIDASE; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ALPHA-TOCOPHEROL PHOSPHATE; PROTEIN BINDING; VITAMIN;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN UNFOLDING; RAT; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BINDING SITE; CELL LINE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; HORSE; KNOCKOUT MOUSE; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN TERTIARY STRUCTURE; SPECTROPHOTOMETRY;

ALPHA-TOCOPHEROL; ANIMALS; APOPTOSIS; BINDING SITES; CELL LINE; CYTOCHROMES C; ENZYME ACTIVATION; HORSES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEROXIDASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SPECTROPHOTOMETRY; VITAMINS;

EID: 84911427050     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.601377     Document Type: Article

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